Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07700862Recruiting
Deep brain stimulation for tremor-dominant Parkinson's disease
This trial compares two ways to place electrodes in the brain to reduce tremors. It may help people with Parkinson's disease whose main symptom is shaking.
ShanghaiAges 18–80 - NCT07699562Recruiting
EMG device study in healthy people and ICU patients
This study tests a device that records muscle activity (EMG) in healthy volunteers and critically ill patients in the ICU. It aims to learn how well the device works in different groups, which could help monitor muscle function in the future.
Evanston, IllinoisAges 18–90 - NCT07702968Recruiting
Low-field MRI for stroke patients in the ER
This trial uses a low-field MRI machine to scan the brains of people with suspected stroke who come to the emergency room. It aims to see if this type of MRI can help doctors make faster and better decisions about treatment.
Leiden, South HollandAges 18 years+ - NCT07698249Enrolling by invitation
Headache diary for migraine patients
This trial tests whether a headache diary can help people with migraine track their symptoms and improve their care.
Edison, New JerseyAges 18 years+ - NCT07703462Enrolling by invitationPhase 1/Phase 2
Personalized therapy for TARDBP ALS
This trial offers a custom-made treatment for people with ALS caused by a TARDBP gene mutation. It uses a personalized medicine approach to target the specific genetic cause of the disease.
Philadelphia, PennsylvaniaAges Any age - NCT07699029Recruiting
Clot removal for stroke in the back of the brain after 24 hours
This study tests a procedure to remove blood clots from large arteries in the back of the brain up to 14 days after a stroke starts. It may help people who have had a stroke more than a day ago and still have significant disability.
Wuhan, HubeiAges 18 years+ - NCT07697664Recruiting
Memory and thinking through exercise in aging
This study looks at whether light-to-moderate physical activity (like walking or stretching) can help memory and thinking in middle-aged and older adults. People with normal thinking, mild memory problems, or Parkinson's disease may join if they aren't already very active.
Atlanta, GeorgiaAges 18–79 - NCT07706114Enrolling by invitation
Walking with FES: a daily life study for MS
This trial tests whether daily use of Functional Electrical Stimulation (FES) can improve real-world walking and daily activities for people with multiple sclerosis. FES uses small electrical pulses to help weak leg muscles move.
San Francisco, CaliforniaAges 22–75 - NCT07702643Recruiting
Walking practice at home after stroke
This study tests a home-based walking program for people who have recently had a stroke. It combines behavioral coaching with guided stepping exercises to help improve mobility and confidence when walking after returning home from the hospital.
Calgary, AlbertaAges 50 years+ - NCT07698236Enrolling by invitation
Temporal interference brain stimulation for Parkinson's disease
This trial tests a new non-invasive brain stimulation method called temporal interference to see if it can improve symptoms of Parkinson's disease. It is for people aged 40 to 80 who are on stable Parkinson's medications and have mild to moderate symptoms.
ShanghaiAges 40–80 - NCT07703761Recruiting
AI analysis of brain tumor MRI scans
This trial uses artificial intelligence to analyze MRI scans from people diagnosed with a type of brain tumor called glioma. It aims to better understand the cancer from diagnosis through treatment, which could help guide future care.
TrentoAges 18–60 - NCT06648954Recruiting
Brain stimulation to improve hand movement in chronic stroke
This study tests whether a brain stimulation technique called high-definition transcranial direct current stimulation (HD-tDCS) can help improve hand and arm movement in people who had a stroke more than a year ago. The stimulation targets the parts of the brain that control movement, and the goal is to see if it can boost recovery when combined with standard therapy.
Hong KongAges Any age - NCT05125146Recruiting
Internet CBT for insomnia versus medicines
This study compares an online form of CBT (a structured therapy for sleep) with sleep medicines for adults with insomnia. It may help you see which approach improves how easily you fall asleep and stay asleep.
Kingston, OntarioAges 18 years+ - NCT05914038Recruiting
Personalized brain stimulation to improve arm recovery after stroke
This trial studies whether personalized rTMS (a noninvasive brain stimulation) can help improve arm and hand strength after a recent stroke. It may help people who still have weaker upper-limb movement within the first few months after stroke.
Taipei County, TaipeiAges 20 years+ - NCT06646510Recruiting
Electrical stimulation for resting tremors in Parkinson's
This trial tests whether gentle electrical stimulation to the skin (called sensory electrical stimulation) can help reduce resting tremors in people with Parkinson's disease. Resting tremors are shaking that happens when your muscles are relaxed, like when your hands are in your lap.
GizaAges 45–60 - NCT06533410Recruiting
Testing a new Chinese pain scale for fibromyalgia diagnosis
This study tests a new Chinese questionnaire to help doctors diagnose fibromyalgia more accurately. It is for people with long-lasting, widespread pain who can fill out a simple form.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06197698Recruiting
Parkinson's and gut-brain connection study
This study is looking at how the bacteria in your gut might affect your brain in Parkinson's disease. It involves two types of brain scans to see differences between people with Parkinson's and healthy volunteers.
DouliuAges 20 years+ - NCT05813392Recruiting
Digital CBT for insomnia in breast cancer survivors
This trial tests a phone-based program (digital cognitive behavioral therapy for insomnia) to improve sleep and daytime functioning. It is for people with long-term insomnia who have finished breast cancer treatment and are currently stable.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06650436Recruiting
Stroke, Delirium, and Long-Term Thinking Changes
This study looks at the link between stroke, delirium (sudden confusion), and long-term thinking problems. It tests whether EEG and MRI scans can help predict who may have trouble thinking clearly after a first stroke.
BrusselsAges 18 years+ - NCT06650969Recruiting
Early detection of cognitive decline in type 2 diabetes
This study is looking at ways to catch early thinking and memory changes in people with type 2 diabetes. By joining, you may help doctors learn how to spot problems sooner and find better ways to help.
Nanjing, JiangsuAges 45 years+ - NCT06053671Recruiting
Understanding genetics in focal epilepsy brain tissue
This study is looking at brain tissue from people with a specific type of epilepsy (Focal Cortical Dysplasia Type II). The goal is to understand what causes the seizures and how they develop, which may help improve future treatments.
LondonAges Any age - NCT04800913Recruiting
Imaging tests during left atrial appendage closure
This study looks at how different imaging tests can help guide a procedure that closes off the left atrial appendage to reduce stroke risk. It may help doctors choose the safest approach during the procedure.
BudapestAges 18 years+ - NCT07689305Recruiting
Video Interaction as Comfort for Kids Before Surgery
This trial tests if a live parent-child video chat or a cartoon before surgery can reduce agitation when a child wakes up from anesthesia. It may help children aged 2-6 who are having planned surgery.
Izmir, İzmirAges 2–6 - NCT07694440RecruitingPhase 2
Study of an experimental pill for adults with PKU
This trial tests an experimental medication taken as a pill to see if it can help people with PKU manage their condition. The study will check if the pill is safe and how it affects blood phenylalanine levels.
Oakland, CaliforniaAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.