Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06480370Recruiting
Optimizing brain monitoring during surgery
This trial tests a way to improve how signals from the brain are monitored during surgery to protect important areas. It might help ensure the surgery is safer and more precise.
BernAges 18 years+ - NCT06469866Recruiting
Deep muscle relaxation and recovery after hysterectomy
This trial tests whether using a deeper level of muscle relaxation during laparoscopic hysterectomy helps patients recover better after surgery. It aims to find out if this approach can reduce pain and speed up return to normal activities.
Anqing, AnhuiAges 18–65 - NCT06451952Recruiting
Virtual darkness therapy for agitation in dementia
This trial tests whether virtual darkness therapy (sitting in a dim, calming environment) can reduce agitation in people with dementia. It is designed for patients at NKS Olaviken hospital who have significant agitation.
Askøy, ErdalAges 50 years+ - NCT06466642Recruiting
Brain training for memory and thinking with HIV
This study tests if two types of computer-based brain exercises can help improve memory, thinking, and daily function in people living with HIV who have mild mental slowdowns. Participants will do about 10 hours of one brain game and 10 sessions of another over 5 weeks.
Cape Town, Western CapeAges 30–50 - NCT07191327Recruiting
Testing brain stimulation for posterior cortical atrophy
This study tests a noninvasive brain stimulation technique called HD-tDCS to see if it can help people with posterior cortical atrophy (PCA), a condition that affects vision and spatial skills. You would receive personalized stimulation sessions, and the study aims to learn if this treatment improves symptoms.
Ann Arbor, MichiganAges 50 years+ - NCT06451874Recruiting
Exercise for older veterans with memory and walking concerns
This study tests whether personalized exercise programs can help older veterans who walk slowly and have mild memory or thinking concerns. The goal is to improve your physical and mental function.
Boston, MassachusettsAges 65 years+ - NCT05707949Enrolling by invitationPhase 3
Long-term safety study of atogepant for kids with migraine
This trial studies the long-term safety (side effects over time) of atogepant tablets in children and teens with migraine. It may help families understand whether the medicine is safe for longer use in ages 6 to 17.
Huntsville, AlabamaAges 6–17 - NCT06419257Recruiting
Virtual reality driving for dementia patients
This trial tests if a virtual reality driving simulator can help people with dementia living in a special care unit. If you can walk and see well, you may be able to take part.
Winnipeg, ManitobaAges 50 years+ - NCT06548802RecruitingPhase 1/Phase 2
Baricitinib for lung injury after brain bleed
This trial tests a pill called baricitinib to see if it helps people recover from lung injury after a brain bleed. It is for patients who need a breathing machine due to ARDS that started within a week of the bleed.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06406842Recruiting
Brain oxygen and stroke risk in carotid surgery
This study looks at whether monitoring oxygen levels in the brain during carotid artery surgery can help predict or prevent a stroke. If you are having this surgery, researchers want to see if a simple monitor on your forehead can warn the surgical team of trouble.
Beijing, Beijing MunicipalityAges 18–80 - NCT05380349RecruitingEarly Phase 1
Personalized testing of drugs for glioblastoma stem cells
This early trial tries to find which medicines might work best for your specific glioblastoma, by testing drugs on cancer “stem cell” samples. If the test finds promising drug options, it may guide a more personalized treatment approach.
Seattle, WashingtonAges 18 years+ - NCT06389721Recruiting
Preventing nerve damage from breast cancer chemotherapy
This study looks at how certain chemotherapy drugs affect the brain and cause nerve damage (peripheral neuropathy) in people with breast cancer. The goal is to find ways to prevent or reduce these side effects so that treatment can be more comfortable and effective.
Houston, TexasAges 18 years+ - NCT05306327Recruiting
Study nerves and breathing after stopping life support
This trial looks at how a person’s nervous system signals change right after life support is withdrawn. It may help doctors better understand what to expect during end-of-life care and how to monitor the process.
Calgary, AlbertaAges 18 years+ - NCT06380192Recruiting
Genetic Epilepsy and Development: A Natural History Study
This study looks at how a specific type of epilepsy with developmental challenges progresses over time. By reusing medical records, the researchers hope to learn more without extra hospital visits.
AmiensAges Any age - NCT06374433Recruiting
How the brain learns: a brain stimulation study
This study explores how the brain learns and adapts (called brain plasticity) using a non-invasive brain stimulation technique. It may help understand learning and perception in healthy young adults.
MilanAges 18–35 - NCT06974617Recruiting
Nerve block vs. Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (sphenopalatine block) and Botox injections. It aims to see which one works better for reducing headache days.
CairoAges 18–65 - NCT06543992RecruitingPhase 2
Chemotherapy for breast cancer that spread to the brain lining
This trial tests a combination of two chemotherapy drugs (thiotepa and methotrexate) given directly into the fluid around your brain and spine through a small implanted device. It aims to treat breast cancer that has spread to the lining of the brain or spinal cord.
Nanjing, JiangsuAges 18–75 - NCT07186023Recruiting
Mindfulness or brain stimulation for older adults in Taiwan
This study compares two approaches—mindfulness training or brain stimulation—to see which helps older adults in Taiwan feel better. If you qualify, you would join either the mindfulness group or the brain stimulation group.
New Taipei CityAges 55 years+ - NCT06615141Recruiting
Virtual reality for arm recovery after stroke
This trial tests whether a more immersive virtual reality (VR) game or a simpler VR game better helps improve arm movement in people who have had a stroke and still have arm weakness. You will use a VR headset or screen to do exercises, and researchers will see which approach works best.
AjmanAges 28–55 - NCT06336083Recruiting
Study of carotid webs in families using ultrasound
This study looks at whether carotid webs (small flaps in the neck artery that can increase stroke risk) run in families. If you or a close relative has a carotid web, researchers will use a special ultrasound to check family members for the same condition.
ToulouseAges 18–65 - NCT05708729Recruiting
Brain stimulation for nerve pain after stroke
This study tests a type of brain “neuromodulation” to reduce central post-stroke pain (CPSP) and to understand how it works and whether it’s safe. It’s for people whose pain has not improved enough with certain standard pain medicines.
LeuvenAges 18–70 - NCT07473024Recruiting
Brain wave guided anesthesia and child behavior
This trial studies whether special brain wave monitoring during anesthesia can help improve children's behavior after surgery. It is for children ages 3 to 10 having certain types of surgery that last more than an hour.
Istanbul, IstanbulAges 3–10 - NCT06336057Recruiting
Mentalizing in adults with narcolepsy type 1
This study looks at how people with type 1 narcolepsy understand their own and others' thoughts and feelings (called mentalizing). It compares them to people with treated sleep apnea to see if there are differences.
ToulouseAges 18 years+ - NCT07473141Recruiting
Measuring walking problems with wearable sensors
This trial uses small wearable sensors to measure how you walk while you are in the hospital. It can help doctors better understand and treat walking difficulties.
Milan, ItalyAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.