Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06322654Recruiting
Comparing two types of robotic rehab for spinal muscular atrophy
This study compares two robot-assisted rehabilitation programs to see which one helps children and young adults with spinal muscular atrophy (SMA) improve their movement and function better. You may join if you have SMA (types 1-4), are up to 21 years old, and are already receiving medication for SMA.
PoznanAges Up to 21 years - NCT06322407Recruiting
Ultrasound-guided neck injection for treating chronic migraine
This study tests whether a nerve block injection near the neck (called stellate ganglion block), guided by ultrasound, can reduce chronic migraine pain. It may be a good option if you have chronic migraine and haven't found relief from standard preventive medications.
Beijing, Beijing MunicipalityAges 18–65 - NCT06292598Recruiting
Gut bacteria and sleep disorder study
This study compares gut bacteria and substances from the gut in people with type 1 narcolepsy versus those without. It aims to understand how gut health might be linked to this sleep disorder.
Nîmes, GardAges 10 years+ - NCT06986967Recruiting
Comparing Blood Flow Methods During Aortic Arch Surgery
This study compares two methods of supplying blood to the brain during surgery on the main artery from the heart (aorta) and the aortic arch. It may help determine the safest way to protect the brain during cooling and surgery.
Durham, North CarolinaAges 18 years+ - NCT07209683Recruiting
Near-infrared light therapy for brain function in adults
This study tests whether shining a special near-infrared light on the head can improve how well your brain works and how clearly you think. It is for healthy younger and older adults who want to help find new ways to support brain health.
Oklahoma City, OklahomaAges 21–85 - NCT06989697RecruitingPhase 3
Cilostazol and ginkgo for memory in older adults with diabetes
This trial tests whether a combination of cilostazol (a blood flow medication) and ginkgo (a herbal supplement) can help protect memory and thinking skills in people over 60 with type 2 diabetes. You may join if your memory is slightly below normal but not severely impaired.
Seongnam-siAges 60 years+ - NCT07190781Enrolling by invitation
Building a stent registry for unruptured brain aneurysms
This trial is collecting information from people who already received a specific type of stent (Lattice Flow-Diverting Dense-Mesh Stent) to treat an unruptured brain aneurysm. The goal is to learn how well the stent works and improve future treatments.
Beijing, Beijing MunicipalityAges 18–80 - NCT06243783Recruiting
Stress and Brain Energy: A Healthy Volunteer Study
This study looks at how stress affects your brain's energy use. It involves an MRI scan and is for healthy, right-handed adults aged 18–40.
ViennaAges 18–40 - NCT06554561RecruitingPhase 1/Phase 2
Pomalidomide with rituximab and methotrexate for brain lymphoma
This trial tests a combination of three drugs (pomalidomide, rituximab, and methotrexate) for people who have just been diagnosed with a type of lymphoma that started in the brain or spinal cord. The goal is to see if this drug cocktail is safe and effective as a first treatment.
Hanzhou, ZhejiangAges 18–75 - NCT07301632RecruitingPhase 2
MDMA for severe chronic nerve pain
This trial tests if MDMA, combined with psychotherapy, can help people with severe chronic nerve pain that hasn't improved with standard treatments. You'll receive either MDMA or a placebo to see if it safely reduces pain and improves your quality of life.
Toronto, OntarioAges 18 years+ - NCT04023656Recruiting
Study of prognosis in people with paroxysmal kinesigenic choreoathetosis
This study looks at how paroxysmal kinesigenic choreoathetosis (PKC) typically progresses over time in people in Korea. It may help doctors better predict outcomes and plan care. You may be asked about your diagnosis and results from brain and brain-wave tests.
SeoulAges 18 years+ - NCT07295769Recruiting
Detecting hidden atrial fibrillation after stroke of unknown cause
This study uses a small patch (M.E.M.O. Patch) to continuously monitor your heart rhythm for hidden atrial fibrillation, a treatable cause of stroke. The goal is to see if the patch can find irregular heartbeats that standard tests might miss.
Seoul, Songpa-guAges 19 years+ - NCT07284472RecruitingPhase 2/Phase 3
Testing drugs for agitation in Alzheimer's disease
This trial tests two new drugs (EXV-802 and EXV-801) to see if they can safely reduce moderate to severe agitation in people with Alzheimer's dementia. If you or a loved one has Alzheimer's and has been experiencing significant agitation for at least two weeks, this study may be an option.
Murrieta, CaliforniaAges 55–90 - NCT06192745Recruiting
Sleep and screen time study for kids 8 to 11
This study looks at how screen time in the evening affects sleep and body clocks in children. It may help families understand how to create healthier bedtime habits.
Houston, TexasAges 8–11 - NCT07287215Recruiting
Motor imagery and daily function in diplegic cerebral palsy
This study tests whether imagining movements (motor imagery) can help improve everyday skills like walking and playing in children with diplegic cerebral palsy. It compares the effects of motor imagery training with standard physical therapy.
BingoelAges 5–18 - NCT07003386RecruitingPhase 2/Phase 3
Galantamine for recent ischemic stroke
This trial tests a plant-based medicine called galantamine, given within 3 days of an ischemic stroke, to see if it helps recovery. It combines Western and Traditional Chinese Medicine approaches and aims to understand how the treatment works.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06162403Recruiting
Nerve stimulation for chemo-related leg pain
This study tests whether a small device that sends gentle electrical pulses to nerves in your leg can relieve pain caused by chemotherapy. If you have ongoing nerve pain in your legs from past chemo, this treatment might offer a new way to manage it.
Houston, TexasAges 18–85 - NCT07219472Recruiting
Scrambler therapy for nerve pain from chemotherapy
This trial tests a non-invasive treatment called Scrambler Therapy for pain caused by nerve damage from chemotherapy. If you have had this kind of pain for at least 3 months, this therapy might help reduce it without using more drugs.
Cleveland, OhioAges 18 years+ - NCT07292415Recruiting
Nerve repair using Matriderm for finger nerve injuries
This trial tests a special material called Matriderm to help repair damaged nerves in fingers or palms after an injury. It compares Matriderm to standard nerve repair to see if it leads to better recovery.
Nice, Alpes MaritimesAges 16–75 - NCT07388043Recruiting
AP-Brain for memory in older adults with memory concerns
This trial tests a supplement called AP-Brain to see if it helps with memory and thinking in healthy middle-aged and older adults who notice memory problems. You would take different doses of the supplement or a placebo for several weeks and complete memory tests.
London, OntarioAges 40–79 - NCT06139458Recruiting
Cooling therapy to prevent nerve damage from chemo
This trial tests if cooling sleeves and gloves during chemotherapy can help prevent nerve damage (peripheral neuropathy) in people with gynecologic cancers. If you are receiving a common chemo drug called paclitaxel, this approach might reduce side effects like numbness or pain in your hands and feet.
Hartford, ConnecticutAges 18 years+ - NCT06132698RecruitingPhase 2
Immunotherapy injected into spinal fluid for lung cancer that has spread to the brain lining
This trial tests giving an immunotherapy drug directly into the spinal fluid for people with non-small cell lung cancer that has spread to the lining of the brain or spinal cord. The goal is to see if this approach can help control the cancer while allowing you to continue other treatments you may already be taking.
Chengdu, SichuanAges 18–75 - NCT06127667Recruiting
Balance, brain health, and aging
This study looks at how your brain and blood vessels work together to keep you balanced as you age. It may help researchers understand why some people stay steady on their feet and others don't.
Minneapolis, MinnesotaAges 21–95 - NCT06130371Recruiting
Stress, Inflammation & Brain in Depression vs. Severe PMS
This study looks at how stress and inflammation affect the brain in women with major depression compared to women with severe PMS (PMDD). It could help find better ways to understand and treat these mood disorders.
Tübingen, Baden-WurttembergAges 18–40
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.