Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,406 recruiting studies in this area right now.
By phase
- Not applicable9,740
- Phase 2783
- Phase 1576
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3124
Top conditions
- Stroke841
- Parkinson Disease427
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke201
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia154
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California681
- Massachusetts299
- New York292
- Florida275
- Texas265
- Maryland246
- Arizona212
- Alabama210
- Illinois188
- Pennsylvania177
Recruiting studies12,404 total
- NCT06230783Recruiting
Speech test for early Alzheimer's detection
This trial uses speech pattern analysis to detect early signs of Alzheimer's. If you're already in a Wisconsin Alzheimer's study, you may help test if your voice can reveal memory changes.
Madison, WisconsinAges 40–80 - NCT06693752RecruitingPhase 2
Ultrasound test for fluid on the brain in babies
This trial uses a special ultrasound with contrast to study fluid on the brain (hydrocephalus) in newborn babies. The aim is to learn more about the condition and improve treatment options.
Philadelphia, PennsylvaniaAges 1 minute–1.5 years - NCT07293546Enrolling by invitationPhase 1/Phase 2
Gene therapy trial for FOXG1 syndrome
This trial tests a gene therapy called FRF-001 for people with FOXG1 syndrome. It aims to see if the treatment is safe and can help improve symptoms.
Houston, TexasAges 2–20 - NCT06608680Recruiting
Brain stimulation study for young adult readers
This study uses a non-invasive brain stimulation technique called theta-burst stimulation to understand how it affects reading and language networks. It may help researchers learn more about how the brain processes reading in healthy young adults.
Atlanta, GeorgiaAges 18–30 - NCT06123182Recruiting
Guided future thinking for exercise and brain health
This study tests whether a technique called 'guided episodic future thinking' (imagining positive future events) can help you stick with a physical activity program and support healthy brain aging. You'll be asked to exercise on a stepper machine and have MRI scans and blood draws.
Kansas City, KansasAges 45–65 - NCT07582367Recruiting
How Foot Arches Affect Walking and Thinking in Older Adults
This study looks at whether the shape of your foot arches—how high or flat your arches are—affects how you walk and your thinking and memory skills. Researchers want to understand if foot structure plays a role in these abilities as we age.
Balıkesir, BigadiçAges 65 years+ - NCT07531511Recruiting
Understanding SLC6A1 Genetic Disorder in Children
This study tracks how children with SLC6A1 genetic mutations develop over time. Researchers will collect information about seizures, development, and daily functioning to better understand the condition and help guide future treatments.
New York, New YorkAges Up to 17 years - NCT06414499RecruitingPhase 3
Tenecteplase for mild stroke within 4.5 hours
This trial tests a clot-busting drug called tenecteplase for patients having a mild stroke (with weakness on one side or trouble speaking) who can get treatment within 4.5 hours. The goal is to see if this drug helps improve blood flow and reduces disability.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06792396Recruiting
Study of children with a certain sleep-related seizure pattern
This research looks back at records of children (up to age 16) who were treated for a condition called electrical status epilepticus in sleep (ESES) or a related brain disorder with sleep-triggered abnormal brain waves. The goal is to learn more about these conditions to improve care.
ColchesterAges 1–16 - NCT06834685Recruiting
Laser therapy for nerve pain after chemotherapy
This study tests a special laser treatment (photobiomodulation) to reduce nerve pain caused by chemotherapy in cancer patients. If you have had nerve pain for at least 3 months after chemo and can attend twice-weekly sessions, this may help ease your pain.
Mougins, Alpes MaritimesAges 18 years+ - NCT07221539Recruiting
Waking the brain with ultrasound during sedation
This study uses focused ultrasound to stimulate a deep brain region and see if it can help people wake up faster from anesthesia. Healthy volunteers will be sedated and monitored while the ultrasound is applied.
Ann Arbor, MichiganAges 18–40 - NCT07317349Recruiting
A study on how a daily time shift affects body rhythms in couples
This study looks at how a small, consistent delay in your daily schedule affects your body's internal clock. It involves you and your partner staying together in a lab for five days.
AarhusAges 23–45 - NCT06111430Recruiting
Long-term effects of radiation on brain and blood vessels
This study looks at long-term effects of radiation therapy on the brain and blood vessels in people who have had head and neck cancer. It aims to understand how radiation may affect your health years later.
TaipeiAges 20–100 - NCT05345483Recruiting
Rescue stent after failed clot removal in brain arteries
This trial looks at using a special stent device to reopen a blocked brain artery when a standard clot-removal procedure did not work. It may help restore blood flow and reduce damage, especially when the stroke area on scans is small enough and the symptoms started within 24 hours.
AschaffenburgAges 18 years+ - NCT06690398RecruitingPhase 3
Study of Lumateperone for Autism-Related Irritability in Teens
This study tests a new medication called Lumateperone to see if it can reduce irritability in children and teens with autism. It's a 3-month trial that compares the study drug to a placebo (a pill with no active medicine) to find out if it helps with mood and behavior.
Dothan, AlabamaAges 5–17 - NCT07726251Recruiting
Heart changes during jaw surgery
This study looks at how your heart and blood pressure change during a type of jaw surgery called bimaxillary orthognathic surgery. It will help doctors understand a reflex that can affect your heart rate during the procedure.
Kirikkale, KırıkkaleAges 18–40 - NCT07040904Recruiting
Mindfulness to help older Latino adults stay mentally sharp
This study tests whether mindfulness training can help older Latino adults stay sharp as they age. Researchers will measure changes in thinking skills and brain health.
St Louis, MissouriAges 65 years+ - NCT06163833RecruitingPhase 2
Stem cell treatment for severe traumatic brain injury
This study tests whether a treatment made from donor stem cells (called mesenchymal stromal cells) can help people recover from a severe traumatic brain injury. The cells are given through a vein within 48 hours of the injury.
Monza, MBAges 18–70 - NCT07724132RecruitingPhase 3
Treatments for sustained response in Alzheimer's disease
This study tests whether a treatment (atomoxetine or metformin) can help people with Alzheimer's disease maintain an improved state for at least 18 months. It may help you or a loved one stabilize symptoms and slow disease progression.
CambridgeAges 55 years+ - NCT06639802Recruiting
Therapy for balance and coordination in ataxic cerebral palsy
This trial tests a hand-arm and leg therapy program to improve balance and coordination in children with ataxic cerebral palsy. It may help your child move more steadily and confidently.
RawalpindiAges 6–15 - NCT07028528RecruitingPhase 2
Study of Levagen+ for diabetic nerve pain
This trial tests if Levagen+ (a supplement) can reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have significant nerve pain in their feet or legs.
Fortitude Valley, QueenslandAges 18–75 - NCT07720609Recruiting
Home versus clinic therapy for arm function after stroke
This trial compares video-based therapy at home to in-clinic therapy for improving arm and hand movement in people who have had a stroke more than six months ago. It may help you regain function in your affected arm.
Lahore, Punjab ProvinceAges 35–75 - NCT07182019Recruiting
Connecting families to fight loneliness in dementia
This study tests a program that helps people with dementia and their loved ones stay in touch through video calls. It aims to reduce social isolation and improve well-being.
Edmonton, AlbertaAges 65 years+ - NCT06137339Recruiting
Daily avocado and cognition in older adults
This study tests whether eating one avocado daily for 6 months can help keep your thinking and memory sharp as you age. You must not currently eat many avocados or vegetables, and be willing to change your diet.
Kansas City, KansasAges 65–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,406 recruiting neurology studies from the U.S. registry right now, out of 19,323 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.