Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable4,687
- Phase 21,190
- Phase 1566
- Phase 3457
- Phase 1/Phase 2368
- Phase 4229
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer480
- Pancreatic Cancer289
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer147
- Crohn Disease134
- Ulcerative Colitis129
- Colon Cancer114
- Hepatocellular Carcinoma (HCC)112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Ovarian Cancer90
- Pancreas Cancer90
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis76
Leading sponsors
- Fudan University100
- Sun Yat-sen University85
- Mayo Clinic75
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- Chinese University of Hong Kong55
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)50
- National Taiwan University Hospital45
Where studies are running
- California443
- Arizona189
- Texas140
- Alabama129
- Florida127
- Massachusetts120
- New York120
- Maryland88
- Ohio80
- Illinois69
Recruiting studies7,607 total
- NCT07775352Recruiting
Ultrasound-guided care for inflammatory bowel disease
This study tests whether using ultrasound to guide treatment can help manage inflammatory bowel disease. You may join if you are having an endoscopy to assess your disease.
BangkokAges 18 years+ - NCT07770113RecruitingPhase 2
Combination treatment for advanced stomach cancer after first-line therapy
This study tests a new combination of drugs (apatinib, nab-paclitaxel, and possibly adebrelimab) for advanced stomach or gastroesophageal junction cancer that has progressed after initial treatment. The goal is to see if this combination can help control the cancer.
Zhengzhou, HenanAges 18–80 - NCT07768384Recruiting
At-home rehabilitation after complex pancreatic surgery
This study tests a 4-week intensive rehabilitation program for people who develop serious complications after surgery to remove part or all of the pancreas. The program combines exercise and nutrition to help you recover better at home after leaving the hospital.
MilanAges 18 years+ - NCT07769437Recruiting
Sweetener study for adults with Crohn's disease
This study looks at how non-nutritive sweeteners (sugar substitutes) might affect people with Crohn's disease. It involves tracking what you eat and answering daily surveys to see if these sweeteners impact your condition.
Chagrin Falls, OhioAges 18–70 - NCT07774143Recruiting
How fasting time before banding affects bleeding risk
This study looks at whether the length of time you fast before a procedure to treat varices (enlarged veins in the esophagus) affects the chance of bleeding after the procedure. The procedure, called banding, places small rubber bands around the veins to stop or prevent bleeding.
AnyangAges 18 years+ - NCT07770425Recruiting
Measuring lesion size during gastrointestinal endoscopy
This study tests a new way to measure the size of abnormal areas found during a routine endoscopy procedure. It may help doctors make more accurate measurements, which could improve diagnosis and treatment planning.
Montreal, QuebecAges 18 years+ - NCT07769346Recruiting
Appendix cancer patient registry for natural history study
This study collects health information from people diagnosed with appendix cancer to better understand the disease over time. Joining helps researchers learn more about appendix cancer and may lead to better treatments in the future.
Springfield, PennsylvaniaAges Any age - NCT07769216Recruiting
Online feeding education for fathers of young children
This study offers an online program to help fathers learn how to support their children with feeding problems. It aims to improve mealtime behaviors and reduce stress for families.
Ankara, AnkaraAges Any age - NCT07767227Recruiting
Blood and fluid study for people having pancreatic cyst surgery
This study collects blood and cystic fluid samples from people who are already scheduled for surgery to remove a worrisome pancreatic cyst. The goal is to learn more about these cysts and possibly improve future diagnosis and treatment.
Newport Beach, CaliforniaAges 18 years+ - NCT07767370RecruitingEarly Phase 1
Two experimental drugs for chronic inflammatory diarrhea
This study tests two experimental capsules, ND-12 and H-6, given together to adults with long-term diarrhea caused by inflammation in the gut, such as active ulcerative colitis. It aims to see if the combination is safe and helps reduce diarrhea and inflammation.
Nanjing, JiangsuAges 18–75 - NCT07769892Recruiting
Blood and stool test for digestive tract cancer screening
This study is testing a new way to screen for cancers of the digestive tract using a simple blood and stool test. It is for people who are already scheduled to have a digestive tract endoscopy, and it may help find cancers earlier without extra invasive procedures.
Zhaoqing, GuangdongAges 45–74 - NCT07770100RecruitingPhase 2
Matching immunotherapy and targeted radiation for advanced cancer
This trial tests combining immunotherapy (a treatment that boosts your immune system to fight cancer) with a targeted type of radiation called SBRT, which precisely delivers high-dose radiation to multiple cancer spots. The main goal is to see if this combination helps control metastatic cancer (cancer that has spread) better than standard care.
Lexington, KentuckyAges 18–99 - NCT07770126Recruiting
Stomach bacteria study for gastric conditions and precancer
This study looks for certain stomach bacteria (other than the common H. pylori) that might be linked to stomach diseases or early signs of cancer. If you have a stomach condition, your participation could help doctors understand these bacteria better.
EdegemAges 18 years+ - NCT07775209Enrolling by invitationPhase 2
Shorter radiation and chemo for anal cancer
This trial tests a shorter course of radiation therapy given with chemotherapy for people with high-risk anal cancer. The goal is to see if the shorter treatment is just as effective but causes fewer side effects and is more convenient.
Burlington, VermontAges 18 years+ - NCT07772362Recruiting
Plant chemical study for people with an ileostomy
This study looks at how plant chemicals (called polyphenols) are absorbed in people with an ileostomy. It aims to understand digestion and could help guide future nutrition advice for ileostomy patients.
ColeraineAges 18–75 - NCT06185556RecruitingPhase 2/Phase 3
New treatments for liver tumors near blood vessels or bile ducts
This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.
Amsterdam, North HollandAges 18 years+ - NCT04498767Recruiting
Radiation to treat a few metastatic spots in rare cancers
This trial studies whether stereotactic (high-precision) radiation given in a few sessions can control rare cancers that have spread to a small number of sites. It aims to help by treating all known spots while keeping side effects manageable.
AnderlechtAges 18 years+ - NCT06569524RecruitingPhase 2
A new drug for NASH with liver scarring
This study tests a new injected drug (TQA2225/AP025) that may help reduce liver fat and inflammation in people with NASH (a type of fatty liver disease with scarring). It’s for adults who have had a recent liver biopsy and MRI confirming NASH and moderate liver fat.
Lu'an, AnhuiAges 18–75 - NCT06505395RecruitingPhase 2
Octreotide injection for advanced neuroendocrine tumors
This trial is testing an injectable medicine called octreotide for people with advanced neuroendocrine tumors of the digestive system or pancreas. It aims to see if the medicine can help control the tumor.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06041477RecruitingPhase 3
Combining treatments for liver cancer before surgery
This study tests whether giving targeted therapy and immunotherapy at the same time or one after the other is better for shrinking liver tumors that can't be removed right now but might be removable after treatment.
Guangzhou, GuangdongAges 18–75 - NCT07763652RecruitingPhase 1
Study of BL-ARC002 for advanced gastrointestinal and other solid tumors
This trial tests an investigational drug called BL-ARC002 for people with advanced or metastatic cancers of the esophagus, stomach, colon, rectum, or other solid tumors. The goal is to see if it is safe and effective in treating these cancers.
Guangzhou, GuangdongAges 18 years+ - NCT07763015RecruitingPhase 2
Resmetirom for children with metabolic liver disease
This study tests a daily pill, resmetirom, to see if it can reduce fat and scarring in the livers of children and teens with MASH, a type of fatty liver disease. It may help improve liver health and prevent further damage.
Indianapolis, IndianaAges 6–17 - NCT07765004Recruiting
Probiotic supplement for constipation relief
This study tests whether a probiotic supplement can improve constipation symptoms like infrequent bowel movements or hard stools. It might help you have more regular, softer stools.
Suzhou, JiangsuAges 18–65 - NCT07766395Recruiting
Daily powder for women's wellness and fitness
This trial tests a daily powder supplement designed to support lean muscle, hormone balance, digestion, and skin, hair, and nail health. If you're an active woman with some common wellness concerns, this study may help you see if the supplement makes a difference.
Las Vegas, NevadaAges 21–45
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting gastroenterology studies from the U.S. registry right now, out of 11,926 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.