Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,599 recruiting studies in this area right now.
By phase
- Not applicable4,683
- Phase 21,187
- Phase 1568
- Phase 3457
- Phase 1/Phase 2366
- Phase 4228
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer478
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Colon Cancer114
- Hepatocellular Carcinoma (HCC)112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- Chinese University of Hong Kong55
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona189
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,599 total
- NCT07588633Recruiting
Fiber Supplement to Help Constipation During Pregnancy
This study tests whether a fiber supplement (Materna® Opti-fiber) can safely relieve constipation in pregnant women. If you're experiencing constipation during pregnancy, this trial may help determine if this supplement is effective for you.
Osasco, São PauloAges 21 years+ - NCT07588880Recruiting
Tracking Odevixibat Safety and Outcomes in PFIC Patients
This study follows patients with PFIC (a rare liver disease affecting bile flow) who are taking or planning to take odevixibat (Bylvay), a medication that helps manage the condition. Researchers will track how well the medication works, any side effects, and long-term health outcomes in Chinese patients.
BeijingAges 6 months+ - NCT06032273Recruiting
Lung Transplant Study for CF Patients and Their Caregivers
This study looks at a website-based program to support people with cystic fibrosis (CF) and their caregivers, helping them prepare for a possible lung transplant. It aims to ease stress, provide information, and improve the transplant journey.
Seattle, WashingtonAges 18 years+ - NCT06719596RecruitingPhase 1/Phase 2
Probiotics and nutrition after pancreas surgery
This trial tests whether taking probiotics with a special liquid nutrition feed after pancreatic surgery can lower the chance of getting an infection. If you are scheduled for this surgery, you may be able to join.
Nanjing, JiangsuAges 18 years+ - NCT06148298Recruiting
Using a blood test to find pancreatic cancer
This study is testing a new blood test that looks for DNA changes to help find pancreatic cancer. It may lead to a way to find cancer earlier.
Orlando, FloridaAges 18 years+ - NCT07591207Recruiting
Pain relief patch after laparoscopic abdominal surgery
This trial tests whether a pain-relief patch (loxoprofen) works well and safely to reduce pain after common laparoscopic surgeries like gallbladder, appendix, or hernia repair. If it works, it could offer patients a non-invasive way to manage post-surgery pain.
Beijing, Beijing MunicipalityAges 18–64 - NCT07589985Recruiting
Hepatitis B and Liver Health Study in Zambia
This research study follows people with hepatitis B (a liver infection) in Zambia to understand how their bodies respond to treatment and what happens to the virus over time. It includes people with hepatitis B alone, those also living with HIV, and those whose hepatitis B has cleared.
LusakaAges 18 years+ - NCT07594925RecruitingPhase 2
Short-course radiation plus immunotherapy and chemotherapy for rectal cancer
This trial tests a combination of brief radiation therapy followed by immunotherapy and chemotherapy for locally advanced rectal cancer that hasn't spread. The goal is to see if this approach helps patients avoid or reduce surgery while controlling their cancer.
TianjinAges 18–75 - NCT07587216Recruiting
Liver Cancer Patient Database Study
This study builds a database of information from liver cancer patients treated at Tongji Hospital. Researchers will collect your medical records and treatment information to better understand liver cancer diagnosis and care over time.
Wuhan, HubeiAges 18 years+ - NCT07591571Recruiting
Digital support program for newly diagnosed pancreatic cancer
This study tests a digital support program led by community health workers for people recently diagnosed with pancreatic adenocarcinoma (a type of pancreatic cancer). The program aims to help patients navigate their diagnosis and treatment.
Loma Linda, CaliforniaAges 1.5 years+ - NCT07592962Recruiting
Long-term Health Study of Lishui City Residents
This study follows healthy adults in Lishui City over time to understand how people stay healthy and live longer. Researchers will collect health information and track your wellbeing to identify factors that contribute to a long, healthy life.
Lishui, ZhejiangAges 30–80 - NCT07594626RecruitingPhase 1/Phase 2
BMS-986504 and Pemetrexed for Advanced Tumors With MTAP Loss
This trial tests a new drug (BMS-986504) combined with an existing chemotherapy (pemetrexed) for advanced solid cancers that have a specific genetic change called MTAP deletion. The trial aims to see if this combination can slow or stop tumor growth in patients whose cancer has progressed despite prior treatment.
Chicago, IllinoisAges 18 years+ - NCT07587970Recruiting
Body Position and Oxygen Levels During Sedated Scope Procedures
This study tests whether your body position during recovery from sedated endoscopy (a camera procedure to examine your stomach and colon) affects your oxygen levels. The researchers want to find the best recovery position to keep your oxygen levels stable and safe.
Yinchuan, NingxiaAges 18 years+ - NCT07587229Recruiting
Predicting chemotherapy response in gastric cancer
This research study analyzes tumor tissue samples to understand why some patients respond better to chemotherapy after gastric cancer surgery. By studying how genes are processed in cancer cells, researchers hope to predict which patients will benefit most from treatment.
Duarte, CaliforniaAges 18 years+ - NCT07588854Recruiting
Liver Stiffness Testing and Biopsy for Chronic Liver Disease
This study compares two non-invasive ultrasound methods (EUS-SWQ and FibroScan) with liver biopsy to see how well they detect liver scarring in patients with chronic liver disease. The goal is to improve how doctors diagnose and monitor liver damage from conditions like hepatitis B and fatty liver disease.
ShanghaiAges 18–80 - NCT07591012Recruiting
Probiotic Supplements for Ulcerative Colitis Remission
This trial tests whether taking sodium butyrate (a short-chain fatty acid) and a specific probiotic yeast called Kluyveromyces marxianus can help keep ulcerative colitis in remission and prevent flare-ups. You'd need to be in remission (symptom-free with no active inflammation) when you start.
PadovaAges 18–75 - NCT07592975Recruiting
Food with Fiber and B-Vitamins for Gut Health in Older Adults
This study tests whether adding special fibers (prebiotics) and B-vitamins to food can improve your gut bacteria, reduce inflammation, and support mental health. You'll eat fortified foods for several weeks while researchers track changes in your digestion and wellbeing.
Coleraine, County LondonderryAges 50 years+ - NCT07593820RecruitingPhase 1
CAR-T Cell Study for Advanced HER2-Positive Cancers
This early-stage trial tests a new type of immune cell therapy called CAR-T cells, which are designed to recognize and attack cancer cells that have a protein called HER2. The cells are made from your own immune cells, trained in the laboratory, and given back to you. The study evaluates how safe the treatment is and whether it can shrink tumors.
Barcelona, CataloniaAges 18 years+ - NCT07594340RecruitingPhase 3
Advanced Liver Cancer Treatment Comparison Study
This study compares two treatment approaches for advanced liver cancer that has spread within the liver but not to other parts of the body. Both treatments combine chemotherapy delivered directly to the liver with immunotherapy drugs to help your immune system fight the cancer.
Guangzhou, GuangdongAges 18 years+ - NCT07586813RecruitingPhase 2
Romiplostim N01 Plus ATRA for Low Platelets After Gut Cancer
This trial tests a combination of two medicines (Romiplostim N01 and ATRA) to raise dangerously low platelet counts that sometimes persist after chemotherapy for digestive cancers. If your platelets stay low even after previous platelet-raising treatments, this study may help.
BeijingAges 18 years+ - NCT07586384Recruiting
Single-Port vs Standard Laparoscopic Surgery for Stomach Cancer
This trial compares two minimally invasive surgical approaches for early-stage stomach cancer affecting the upper portion. Researchers want to see if a newer single-port technique (using one small incision) works as well as traditional laparoscopic surgery (using multiple small incisions) and may cause less pain or faster recovery.
Wenzhou, ZhejiangAges 18–80 - NCT07587268Recruiting
Understanding Your Appendiceal Cancer Through Genetic Testing
This research study uses genetic and molecular testing on archived tumor samples to better understand appendiceal cancer and predict how it may progress. The goal is to help doctors personalize treatment plans based on the specific characteristics of your cancer.
Durate, CaliforniaAges 18 years+ - NCT07592013Enrolling by invitation
Ancestry Supplements for Fatty Liver Disease
This study tests whether a special supplement (made from cacao, nopal, and crickets) can help improve fatty liver disease in people with excess body fat. Fatty liver disease happens when fat builds up in the liver, and this trial investigates whether these natural ingredients can reduce that buildup.
Guadalajara, GuadalajaraAges 18–60 - NCT07586462Recruiting
Deep Nerve Block for Abdominal Surgery Pain Relief
This trial tests a nerve block—a targeted numbing injection near abdominal muscles—to help reduce pain after abdominal surgery. Researchers want to see if this technique works well alongside standard anesthesia to help you recover more comfortably.
CrotoneAges Any age
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,599 recruiting gastroenterology studies from the U.S. registry right now, out of 11,991 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.