Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,371 recruiting studies in this area right now.
By phase
- Not applicable978
- Phase 2168
- Phase 399
- Phase 146
- Phase 434
- Phase 1/Phase 232
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma80
- Dysphagia73
- Hearing Loss61
- Tinnitus31
- Hearing Loss, Sensorineural25
- Nasopharyngeal Carcinoma (NPC)24
- Allergic Rhinitis23
- Head and Neck Cancer22
- Oropharynx Cancer21
- Stroke20
- Sensorineural Hearing Loss18
- Nasopharyngeal Cancinoma (NPC)17
- Chronic Rhinosinusitis With Nasal Polyps15
- Oropharyngeal Cancer15
- Nasopharyngeal Cancer14
- Vestibular Schwannoma14
- Head and Neck Squamous Cell Carcinoma13
- Chronic Rhinosinusitis (CRS)12
Leading sponsors
- Sun Yat-sen University59
- Eye & ENT Hospital of Fudan University17
- Cairo University15
- Assistance Publique - Hôpitaux de Paris14
- NYU Langone Health14
- Mayo Clinic12
- National Cancer Institute (NCI)12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Cochlear9
Where studies are running
- California62
- Maryland37
- New York35
- Florida30
- Massachusetts21
- Illinois20
- Texas18
- Arizona17
- Colorado16
- Alabama15
Recruiting studies1,371 total
- NCT07678086Recruiting
Breathing tube pressure and sore throat in children's appendix surgery
This trial tests whether carefully managing the pressure in the breathing tube during surgery can help prevent a sore throat in children after they have their appendix removed by keyhole surgery. It may help your child have a more comfortable recovery.
Ankara, YenimahalleAges 6–18 - NCT06788002RecruitingPhase 2
Low-dose radiation and chemoimmunotherapy for NPC with liver spread
This trial tests a combination of low-dose radiation, chemotherapy, and immunotherapy for nasopharyngeal cancer that has spread to the liver. It aims to see if this approach can help shrink tumors and improve outcomes.
Changsha, HunanAges 18–70 - NCT07039435Recruiting
Perceptual adaptation after cochlear implant
This study looks at how people adapt to hearing with a cochlear implant. It's for adults who are getting one implant in one ear while the other ear has normal or near-normal hearing.
New York, New YorkAges 18 years+ - NCT07451028Recruiting
Mouth training device for swallowing problems after stroke
This trial tests a device that strengthens mouth muscles to help people who have trouble swallowing after their first stroke. It may improve your ability to swallow safely.
Hammel, JutlandAges 18 years+ - NCT06789445RecruitingPhase 1/Phase 2
Cell therapy for inherited retinal disease (CLARICO)
This study tests a new cell therapy (OpCT-001) for adults with inherited retinal diseases that affect the light-sensing cells. It aims to see if the treatment is safe and possibly helps improve vision.
Los Angeles, CaliforniaAges 18 years+ - NCT06709092Recruiting
Testing Lupatadine for dust mite allergies
This study tests a new tablet (Lupatadine Fumarate) for people with nasal allergies caused by dust mites. It looks at how well the medicine works and what it does in the body.
Nanjing, JiangsuAges 18–65 - NCT06713265Recruiting
Parkinson's: freezing while walking and swallowing
This study looks at a possible link between two specific Parkinson's symptoms: freezing while walking and freezing of the throat muscles during swallowing. It aims to understand if people who have one type of freezing are more likely to have the other, which may guide future therapies.
Saint-Sébastien-de-MorsentAges 18 years+ - NCT06714149Recruiting
How nitrogen pollution affects pollen allergies
This study looks at how pollution from nitrogen in the environment affects pollen allergies in Belgium. It may help explain why your allergy symptoms change depending on where you live.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06716125Recruiting
Lifestyle changes for obese men with sexual and hearing issues
This trial tests whether lifestyle changes can help obese men who have both sexual difficulties and ringing in the ears. It might improve your overall health and these symptoms.
Dokki, Giza GovernorateAges 35–45 - NCT06722170Recruiting
Gene therapy study for hearing loss caused by OTOF gene mutation
This trial tests a gene therapy called EH002 for people with severe or profound hearing loss due to changes in the OTOF gene. The treatment aims to help the ear hear better by replacing the faulty gene.
Zhengzhou, HenanAges 6 months+ - NCT06723262Recruiting
Testing a new sound tuning for cochlear implant users
This trial studies a new way to adjust a cochlear implant's sound settings based on how the ear naturally processes pitches. It may help improve speech understanding over 6 months compared to standard settings.
LimogesAges 18 years+ - NCT06725966Recruiting
Personalized treatment for persistent BPPV
This trial tests a new way to treat a common inner ear condition called BPPV that hasn't improved with standard head maneuvers. It aims to help people whose dizziness keeps coming back.
Santiago de Compostela, A CoruñaAges 18–100 - NCT06726928Recruiting
Stent for pulsatile tinnitus from narrowed head vein
This trial tests a special stent (a small mesh tube) placed in a narrowed vein in the head to stop a bothersome whooshing sound in the ear (pulsatile tinnitus) that hasn't gone away.
ParisAges 18 years+ - NCT06731881Recruiting
Light therapy to prevent infections after sinus or nose surgery
This study tests if a special light therapy can help prevent infections after sinus or nose surgeries. The treatment is given in addition to standard care and might lower the chance of needing more antibiotics.
London, LondonAges 16 years+ - NCT06732414Recruiting
Long-term study of multiple allergic diseases
This study creates a biorepository to collect and store samples (blood, nasal fluid, skin swabs) from people with allergies, asthma, sinus disorders, or immune dysregulation. It aims to better understand these conditions over time, which may help develop better treatments.
Bethesda, MarylandAges 3–100 - NCT06733948RecruitingPhase 2
Dental stent to protect taste during NPC radiation
This trial tests whether a custom-fitted dental stent (like a mouthguard) can help protect your sense of taste during radiation and chemotherapy for nasopharyngeal cancer. If you qualify, you'll receive either standard care or the stent, and your taste changes will be tracked.
SingaporeAges 21–100 - NCT06737185Recruiting
Comparing two ways to set a cochlear implant
This trial tests if a new method for programming cochlear implants helps people understand speech better than the usual method. If you are an adult getting a cochlear implant, this study could help improve how you hear.
DijonAges 18 years+ - NCT06737549RecruitingPhase 4
Electroacupuncture and NGF for swallowing problems after stroke
This study tests whether a specific type of electroacupuncture (a gentle needle therapy with mild electrical pulses) plus a nerve growth factor injection can help people who have trouble swallowing after a recent stroke. The goal is to see if this combination improves swallowing function better than standard care.
Hangzhou, ZhejiangAges 18–80 - NCT06738823Recruiting
Wii Fit vs. Vestibular Rehab for Vertigo Balance
This study compares two types of balance training—Wii Fit exercises and standard vestibular rehab—to see which helps people with BPPV (a common cause of vertigo). If you have moderate BPPV, you may join to help improve your balance.
IslamabadAges 30–60 - NCT06743295Recruiting
AI noise reduction in Phonak hearing aids
This study tests a new AI feature in Phonak hearing aids to reduce background noise. It may help people with hearing loss, whether or not they already use hearing aids, and even those with one cochlear implant.
Rochester, MinnesotaAges 18–110 - NCT06747390RecruitingPhase 1
Lidocaine injection before throat cancer surgery
This early-phase trial tests whether injecting lidocaine (a numbing medicine) into the tumor before surgery can help with pain or other outcomes in people with oropharyngeal cancer. It's for patients who are already scheduled for a scope procedure and surgery at the University of Pennsylvania.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06749899RecruitingPhase 3
Immunotherapy with chemoradiation for advanced nasopharyngeal cancer
This trial tests a combination of a new immunotherapy (QL1706) plus standard chemoradiation for people with advanced nasopharyngeal cancer that hasn't spread to distant organs. The goal is to see if adding this drug helps control the cancer better than standard treatment alone.
Fuzhou, FujianAges 18–65 - NCT06752239RecruitingPhase 3
Optimizing radiation to protect thyroid in nasopharyngeal cancer
This trial tests a way to adjust radiation therapy to better protect the thyroid gland during treatment for nasopharyngeal carcinoma. It aims to reduce thyroid damage while still effectively treating the cancer.
Nanchang, JiangxiAges 18–70 - NCT06763289Recruiting
Comparing new blood tests for early nasopharyngeal cancer
This study is testing if a new blood test can help find nasopharyngeal cancer early. It compares different methods to see which works best. This could help people get diagnosed and treated sooner.
Guangzhou, GuangdongAges 40–75
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,371 recruiting otolaryngology studies from the U.S. registry right now, out of 2,216 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.