Otolaryngology
Ear, nose & throat clinical trials
Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We’re tracking 1,269 recruiting studies in this area right now.
By phase
- Not applicable890
- Phase 2154
- Phase 3103
- Phase 147
- Phase 431
- Phase 1/Phase 230
- Phase 2/Phase 314
Top conditions
- Nasopharyngeal Carcinoma73
- Dysphagia66
- Hearing Loss61
- Tinnitus29
- Hearing Loss, Sensorineural24
- Nasopharyngeal Carcinoma (NPC)24
- Head and Neck Cancer23
- Allergic Rhinitis22
- Oropharynx Cancer21
- Nasopharyngeal Cancinoma (NPC)18
- Sensorineural Hearing Loss18
- Stroke17
- Oropharyngeal Cancer14
- Vestibular Schwannoma14
- Chronic Rhinosinusitis With Nasal Polyps13
- Deafness13
- Head and Neck Squamous Cell Carcinoma13
- Nasopharyngeal Cancer13
Leading sponsors
- Sun Yat-sen University57
- Assistance Publique - Hôpitaux de Paris14
- Eye & ENT Hospital of Fudan University14
- National Cancer Institute (NCI)14
- Cairo University13
- NYU Langone Health13
- Mayo Clinic12
- Johns Hopkins University11
- Ming-Yuan Chen11
- Massachusetts Eye and Ear Infirmary10
Where studies are running
- California61
- Maryland38
- Florida32
- New York32
- Massachusetts24
- Illinois20
- Texas20
- Alabama15
- Arizona15
- Colorado15
Recruiting studies1,269 total
- NCT06305676Recruiting
A study for early detection of HPV throat cancer
This study looks for early signs of HPV-related throat cancer. If you've just been diagnosed and haven't started treatment, your blood or saliva samples may help improve future screening tests.
Tampa, FloridaAges 18 years+ - NCT06305039Enrolling by invitation
Better hearing with two cochlear implants
This study tests how well people with two cochlear implants (or one cochlear implant and one hearing ear) can hear in complex, noisy settings. It aims to improve how these devices help in everyday listening situations.
Bethesda, MarylandAges 18–85 - NCT06309225Recruiting
Adjusted Chemoradiation for HPV Throat Cancer in Older Adults
This trial tests adjusting the dose of chemotherapy and radiation for older adults (65+) with HPV-related throat cancer. The goal is to find a treatment that is effective but gentler on the body.
Jacksonville, FloridaAges 65–99 - NCT03751566Recruiting
Acupuncture to ease short-term side effects of head and neck radiation
This trial studies whether adding acupuncture to standard radiation care can reduce short-term side effects from radiation for head and neck tumors. You might qualify if you are having treatment with the goal of cure or after-surgery prevention and can reliably complete symptom/side-effect tracking.
BrnoAges 18 years+ - NCT06282601Recruiting
Music and language study for older adults with hearing loss
This study tests whether listening to rhythmic or non-rhythmic music can help improve sentence understanding in older adults with age-related hearing loss. It aims to see if music patterns can boost language skills.
DijonAges 70 years+ - NCT06287034Recruiting
Free flap surgery after total laryngectomy for laryngeal cancer
This trial tests whether using a free or pedicled tissue flap during total laryngectomy reduces the risk of a pharyngocutaneous fistula (an abnormal opening between the throat and skin). It is for people whose laryngeal cancer came back after radiation or chemoradiation.
Rome, RomeAges 18 years+ - NCT06277050RecruitingPhase 3
Toripalimab and capecitabine after chemo-radiation for high-risk nasopharyngeal cancer
This trial tests whether adding the immunotherapy drug toripalimab to the chemotherapy pill capecitabine after standard treatment helps prevent nasopharyngeal cancer from coming back. It is for people with high-risk features who have already had chemo and radiation.
Ganzhou, JiangxiAges 18–70 - NCT06291402Recruiting
Nasal packing duration and sore throat after nose surgery
This study compares how long nasal packing stays in place after septorhinoplasty surgery and whether it affects sore throat. It may help doctors choose the best packing duration to reduce discomfort.
Tanta, EgyptAges 20–40 - NCT05956587RecruitingPhase 2
Testing two study drugs for advanced lung cancer and other tumors
This Phase 2 study tests a combination of two experimental medicines in people with advanced or metastatic solid cancers, including non-small cell lung cancer and nasopharyngeal cancer. It aims to see whether the drugs can shrink tumors and improve outcomes, while carefully checking safety and eligibility.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06259292Recruiting
HHT patient registry tracking long-term outcomes
This registry collects health information from people with HHT over time to better understand the disease and improve care. Joining does not involve any experimental treatment, but your data will help researchers learn more about HHT.
Birmingham, AlabamaAges Any age - NCT06254911RecruitingPhase 2
Immunotherapy before surgery for HPV-related throat cancer
This trial tests whether giving the drug atezolizumab before surgery can help shrink HPV-related throat cancer and improve outcomes. Atezolizumab helps your immune system fight cancer cells.
Atlanta, GeorgiaAges 18 years+ - NCT06271707RecruitingPhase 4
Nerve block for surgery pain relief
This trial tests a nerve block (stellate ganglion block) to see if it helps reduce pain after surgery to remove part or all of the lung or esophagus. It may be an option for adults aged 18-85 having these procedures.
Minneapolis, MinnesotaAges 18–85 - NCT06258837Recruiting
Personalized surgery for sleep apnea in children with small tonsils
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
Ann Arbor, MichiganAges 2–17 - NCT06268340Recruiting
Hearing preservation with ECochG monitoring during cochlear implant
This trial tests a new technique to help preserve your natural hearing during cochlear implant surgery. It uses a special monitoring method (ECochG) to see if the implant can be placed while keeping your remaining hearing intact.
Ghent, GentAges 18 years+ - NCT06229717Recruiting
Balance and hearing study for children with hearing loss
This study looks at how hearing loss affects balance in children aged 3 to 10. It tests balance and inner ear function to help understand the connection between hearing and balance problems.
HerningAges 3–10 - NCT06229730Recruiting
Normal balance and hearing in Danish children
This study measures normal balance and inner ear function in healthy children aged 6 months to 10 years. It helps doctors understand what is typical for kids, which can improve care for those with balance issues.
HerningAges 6 months–10 years - NCT06237790Recruiting
Gene therapy versus cochlear implants for congenital hearing loss
This study looks at how well gene therapy or cochlear implants help restore hearing in people with severe hearing loss from birth. It compares the outcomes of these two treatments to see which is more effective.
Beijing, Beijing MunicipalityAges 6 months+ - NCT06229704Recruiting
Balance and dizziness study for children aged 6 months to 10 years
This study tests balance and inner-ear function in children who have delays in gross motor skills or dizziness/balance problems. It aims to understand these issues better and may help guide future care.
HerningAges 6 months–10 years - NCT06239727RecruitingPhase 3
Reduced-dose radiotherapy for stage III nasopharyngeal cancer based on response
This trial tests whether a lower dose of radiation can safely treat stage III nasopharyngeal cancer if you have already responded well to initial chemotherapy plus immunotherapy (Camrelizumab). The goal is to reduce side effects while still controlling the cancer.
Fuzhou, FujianAges 18–65 - NCT06123650Recruiting
Magnetic brain stimulation plus therapy for swallowing after stroke
This study tests whether adding a gentle magnetic brain stimulation (called rTMS) to standard swallowing therapy can help prevent pneumonia in people who have trouble swallowing after a stroke. It might reduce the risk of getting a lung infection.
Giza, Giza GovernorateAges 49–65 - NCT06190171Recruiting
Breathing strength training for heart transplant patients
This trial tests whether a special breathing and muscle-strengthening exercise program can help people waiting for a heart transplant. It is designed to improve your respiratory strength and overall conditioning before surgery.
Nashville, TennesseeAges 18–90 - NCT06197776Recruiting
Predicting treatment success for advanced nasopharyngeal cancer
This study uses advanced testing (multi-omics) to predict if combining chemoradiation with immunotherapy works better for nasopharyngeal cancer that has returned or spread. It aims to find the right treatment for each person.
Guangzhou, GuangdongAges 18–70 - NCT06192771Recruiting
Swallowing and speech therapy after tongue cancer surgery
This trial tests whether starting speech and swallowing therapy early after surgery helps people with tongue cancer recover their ability to eat and talk. It is for patients having part of their tongue removed and rebuilt with a tissue flap.
Toronto, OntarioAges 18 years+ - NCT06165536Recruiting
Using voice strategies to reduce vocal fold pressure
This study tests different ways of using your voice to reduce pressure on vocal fold lesions caused by overuse. If you are between 18 and 40, have been diagnosed with such lesions, and are going to voice therapy, you may be able to join.
Los Angeles, CaliforniaAges 18–40
Common questions
- How many ear, nose & throat clinical trials are recruiting?
- Clin2 is tracking 1,269 recruiting otolaryngology studies from the U.S. registry right now, out of 2,074 we cover in this area in total.
- What does “Ear, nose & throat” cover here?
- Hearing, balance, and conditions of the ears, nose, sinuses, and throat. We group each study into ear, nose & throat based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a ear, nose & throat trial near me?
- Use the search to filter ear, nose & throat studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.