Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3131
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California132
- Arizona68
- Florida42
- Maryland39
- Texas38
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT03249337RecruitingPhase 4
Ripasudil drops before Descemet stripping surgery in Fuchs disease
This trial tests whether Glanatec (ripasudil) eye drops help patients with Fuchs endothelial dystrophy get better results from Descemet stripping surgery. It may help improve vision and reduce symptoms for people whose vision problems come mainly from the Fuchs changes in the cornea.
Glenview, IllinoisAges 18–91 - NCT01403402Recruiting
Study of congenital muscle disease patients and their families
This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.
Lakewood, CaliforniaAges Any age - NCT04461444Recruiting
Cohort study for Bardet-Biedl and Alström syndromes
This study follows people with Bardet-Biedl syndrome (BBS) or Alström syndrome (ALMS) to spot early vision, metabolic (body chemistry/energy), and kidney problems. You may be asked to have clinical checks over time to help researchers better understand how these complications develop.
StrasbourgAges 4 months+ - NCT01277419Recruiting
Study of new cases of several spine, joint, and eye diseases
This study enrolls people who have recently been diagnosed with certain inflammatory conditions affecting the spine, joints, or the eye. Researchers are looking to better understand how these illnesses start and how they may be linked, which could help guide future care.
BerlinAges Any age - NCT05080010RecruitingPhase 3
Extra chemo after eye removal for high-risk retinoblastoma
This Phase 3 study tests whether giving chemotherapy after the eye has been removed can lower the chance of retinoblastoma coming back for children with high-risk disease. You may be screened if your child had one eye affected and meet the staging and treatment history requirements.
Guangzhou, GuangdongAges Any age - NCT05136209Recruiting
Surgery for children’s cataracts: with or without vitrectomy
This trial compares two surgical techniques to treat cataracts present since birth in children, to see which approach works better. It may help your child by improving surgical outcomes and recovery.
Guangzhou, GuangdongAges 1 month–18 years - NCT05136950Recruiting
Tracking side effects after secondary lens surgery for cataracts
This study follows children who had congenital cataract surgery to see how often glaucoma-related side effects happen after getting a secondary intraocular lens. It may help doctors better prevent and catch eye pressure problems after these surgeries.
GuangzhouAges 1.5 years–14 years - NCT02194816Recruiting
Online survey study for people with Parkinson’s or Parkinsonism
This study looks at how changing certain factors over time relates to symptoms in Parkinson’s disease and related conditions. You may help researchers by completing longer online surveys every 6 months for 5 years.
Kenmore, WashingtonAges 19 years+ - NCT04420156Recruiting
Study to understand eye disease risk in premature babies
This study looks at newborn eye exams and genetic information to better understand why some premature infants develop a serious vision problem called ROP. You may be invited because your baby needs routine eye screening or is being moved for specialized eye care.
Palo Alto, CaliforniaAges Up to 1 year - NCT03455478Recruiting
Study of adult vision health in Shanghai residents
This study looks at the eye health of adults who live in Shanghai. It may help researchers understand vision problems in the local population and improve future eye care.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT05445063RecruitingPhase 1
iPSC eye-cell transplant for late dry macular degeneration
This Phase 1 study tests an experimental transplant made from your own cells to try to improve vision in people with advanced “late dry” age-related macular degeneration (AMD). It focuses first on safety, and may help some participants with limited central vision.
Beijing, Beijing MunicipalityAges 50–75 - NCT02329210Recruiting
Registry study for people with Bardet-Biedl syndrome
This study is a registry that collects health and genetic information from people with Bardet-Biedl syndrome. It may help researchers better understand the condition and improve future care by building a clear group of eligible patients.
Marshfield, WisconsinAges Any age - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05472844Recruiting
Study of cataracts in children under 18
This is a research study that follows children with cataracts to learn more about the condition. If your child is under 18 and has a cataract in one or both eyes, this study may be able to include them.
Guangzhou, GuangdongAges Up to 18 years - NCT05563623Recruiting
Study of people at risk for angle-closure progression
This study follows people who have eye anatomy that suggests a higher risk of angle closure, but who do not currently have high eye pressure or glaucoma damage. It aims to understand how often and how fast this risk can progress, which may help guide earlier monitoring or prevention.
Beijing, BeeijingAges 40–75 - NCT03321201Recruiting
Glue or cautery for a first pterygium surgery
This study compares two methods used during surgery for a first-time pterygium (a non-cancer growth on the eye surface): using a special glue versus cauterization. It may help determine which method works better to keep the growth from coming back and to heal more smoothly.
SplitAges 18 years+ - NCT05605314Recruiting
Study different types of dry eye in Sjögren’s
This study looks at patients with Sjögren’s-related dry eye to understand how different subtypes affect tear function and eye symptoms. It may help doctors better sort out dry eye types, which can guide more tailored care.
BeijingAges 18–80 - NCT04912843RecruitingPhase 2/Phase 3
Gene therapy for inherited optic nerve vision loss
This trial tests a gene therapy injection into the eye to improve vision in people with a specific type of inherited optic nerve disease called Leber’s hereditary optic neuropathy (LHON). It is aimed at people who have a particular genetic change and a history of vision loss lasting long enough to measure change, while checking for safety first.
BeijingAges 12–75 - NCT05340647Recruiting
Study of micro-invasive glaucoma surgery options
This trial studies outcomes after certain minimally invasive glaucoma surgeries, including the Preserflo microshunt. It may help improve how safely and effectively glaucoma surgery is done, and how patients are followed afterward.
OsloAges 18 years+ - NCT05072262RecruitingPhase 4
Topical anti-inflammatory eye drops after corneal transplant
This study tests whether anti-inflammatory eye drops (nepafenac, an NSAID) can help reduce swelling in the macula (the sharp-vision part of the eye) after certain cornea transplant surgeries. It compares outcomes in adults having DSAEK or DMEK who can safely use the study drops.
OsloAges 18 years+ - NCT03635645Recruiting
Testing stimulation in people with an implanted retinal prosthesis
This study looks at how retinal stimulation works for people who already have an Argus II retinal prosthesis implanted. It may help researchers understand how well the stimulation creates a visual perception and how reliably people can do the required testing.
Ann Arbor, MichiganAges 25–89 - NCT05663684RecruitingPhase 4
Topical numbing drops to reduce pain during tear duct testing
This Phase 4 trial studies whether numbing eye drops (proparacaine 0.5%) can reduce pain during a procedure called probing and irrigation of the tear drainage system. If you need this test for ongoing watery eyes, the trial may help make the procedure more comfortable.
New Orleans, LouisianaAges 18 years+ - NCT05705778Recruiting
Blood biomarker study in children with amblyopia
This trial looks at a blood test (a “biomarker”) in children with amblyopia, a common vision development problem. It may help researchers understand what changes go along with treatment and vision improvement.
Guangzhou, GuangdongAges 3–12 - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,739 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.