Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3132
- Phase 2121
- Phase 1121
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California142
- Arizona65
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT07224542Enrolling by invitation
Smart contact lenses to monitor glaucoma
This study tests a smart contact lens that may help monitor glaucoma by measuring eye pressure. It is looking for people with glaucoma (who already use eye-drop medicine) and healthy adults without glaucoma to see if the lens works well over time.
Bloomington, IndianaAges 22 years+ - NCT07018323RecruitingPhase 2
Study of IMVT-1402 for Graves' disease
This trial tests an investigational drug called IMVT-1402 for people with Graves' disease whose thyroid is still overactive even while taking standard antithyroid medication. The goal is to see if the drug can better control thyroid hormone levels.
Tucson, ArizonaAges 18–75 - NCT07425574Recruiting
Study on how Stargardt eye conditions progress in children and adults
This study observes how Stargardt disease and similar eye conditions change over time in children and adults. It aims to learn more about the disease progression to help develop future treatments.
Phoenix, ArizonaAges 6 years+ - NCT07780890Recruiting
Measuring eye hydration with light
This study uses a non-invasive imaging technique called Brillouin hydration mapping to measure hydration levels in different parts of the eye. It aims to help doctors better understand how hydration affects eye health and disease.
Boston, MassachusettsAges 20–79 - NCT07614776RecruitingPhase 3
New Eye Injection Treatment for Age-Related Macular Degeneration
This study tests whether a new eye injection called ABP 938 works as well as or better than the current standard treatment (Eylea) for wet age-related macular degeneration—a condition that causes vision loss in the center of your sight. You would receive injections into your eye every month for a year.
Fullerton, CaliforniaAges 50 years+ - NCT07440225RecruitingPhase 2/Phase 3
Testing a new drug for wet macular degeneration
This trial tests a new medicine called EYE201/MK-8748 for people who have wet age-related macular degeneration (a condition where abnormal blood vessels grow under the retina). It's for those who haven't had treatment before and were diagnosed recently.
Scottsdale, ArizonaAges 50 years+ - NCT05156398RecruitingPhase 3
Rimegepant to prevent migraine attacks in children
This trial studies whether rimegepant can reduce how often migraine attacks happen in children and teens. It also looks at safety and how well the treatment fits day-to-day life and school activities.
Fort Smith, ArkansasAges 6–17 - NCT07571538Recruiting
VisionApp Ghosting Study for People with Mild Nearsightedness
This research study tests an app designed to understand how people with mild nearsightedness experience visual ghosting (blurred or doubled images). Your participation could help improve vision correction technology.
Bloomington, IndianaAges 8 years+ - NCT07305818RecruitingPhase 1
Testing a new drug for Graves' disease
This study tests a new medication called MER511 for adults with Graves' disease. The goal is to see if it is safe and how it works when taken once or multiple times.
Torrance, CaliforniaAges 18–65 - NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT07441642RecruitingPhase 2
Study of FWY003 for geographic atrophy in age-related macular degeneration
This trial tests an investigational drug FWY003 against a placebo to see if it can slow or stop the progression of geographic atrophy, a form of advanced age-related macular degeneration that causes vision loss.
Huntington Beach, CaliforniaAges 50 years+ - NCT07270133Recruiting
Diabetes eye health observation study
This study observes how diabetes affects vision over time in people with diabetes. It helps doctors better understand eye health without any treatment or intervention.
Augusta, GeorgiaAges 18 years+ - NCT05197270RecruitingPhase 1/Phase 2
Gene therapy for wet age-related macular degeneration
This study tests a new gene therapy called 4D-150 for people with wet age-related macular degeneration (AMD). It aims to reduce the need for frequent anti-VEGF injections by delivering a long-lasting treatment into the eye.
Phoenix, ArizonaAges 50 years+ - NCT06847542RecruitingPhase 3
Study of a refillable eye implant for wet AMD
This trial tests a refillable eye implant (PDS) that slowly releases medication to treat wet age-related macular degeneration (nAMD). It aims to see if replacing the implant every 36 weeks works as well as regular eye injections.
InnsbruckAges 50 years+ - NCT07722546RecruitingPhase 2
Felzartamab for Graves' disease in adults
This study tests an investigational drug called felzartamab to see if it can help control thyroid function in adults with Graves' disease. It may offer a new option if you are still having symptoms despite anti-thyroid medication.
Los Angeles, CaliforniaAges 18–75 - NCT07166848Enrolling by invitation
Electrical stimulation study for dry eye from graft vs. host disease
This trial tests if gentle electrical stimulation around the eye can help relieve dry eye symptoms caused by chronic graft versus host disease (a complication after a stem cell or bone marrow transplant). It is for people with moderate to severe dry eye who have not had recent eye surgeries or certain other eye problems.
Boston, MassachusettsAges 18–75 - NCT07648095Recruiting
Lacrifill treatment for dry eyes before cataract surgery
This trial tests whether a treatment called Lacrifill can help improve dry eye symptoms in patients preparing for cataract surgery. Lacrifill is designed to keep the eye surface moist and healthy during the surgical process.
Largo, FloridaAges 40 years+ - NCT07173803RecruitingPhase 2
PSP clinical trial testing new treatments
This trial tests potential new treatments for progressive supranuclear palsy (PSP), a brain disorder affecting movement, balance, and thinking. It aims to see if these treatments are safe and slow the disease. You may be able to join if you have a specific type of PSP and are in fairly good health.
Palo Alto, CaliforniaAges 41–86 - NCT07596849RecruitingPhase 3
Testing a New Injection for Graves' Disease
This study tests efgartigimod, a new medicine given by injection under the skin, to see if it can help control Graves' disease (an overactive thyroid condition). The goal is to reduce the need for other thyroid medications or help people stop taking them.
SurreyAges 18 years+ - NCT06962839RecruitingPhase 2
Study of BI 1815368 for diabetic macular edema
This trial tests an experimental medication (BI 1815368) given as an eye injection for people with diabetic macular edema, a condition where fluid builds up in the center of the retina and blurs vision. The study aims to see if this new treatment can reduce swelling and improve vision.
Phoenix, ArizonaAges 18 years+ - NCT07567040RecruitingPhase 3
Delaying Nearsightedness Onset in Children
This study tests whether low-dose atropine eye drops can prevent or slow down nearsightedness in children ages 6–11 who don't yet need glasses. The goal is to keep children's vision stable and reduce their need for corrective lenses as they grow.
Birmingham, AlabamaAges 6–11 - NCT07734844RecruitingPhase 3
New vs existing treatment for diabetic macular edema
This study compares a new medication, tabirafusp tedromer, to an existing treatment, aflibercept, for people with diabetic macular edema (swelling in the back of the eye from diabetes). It may help if your DME hasn't improved or you're looking for a new option.
Glendale, CaliforniaAges 18 years+ - NCT06360133RecruitingPhase 3
New eye drop for dry eye disease
This study tests a new eye drop (5% VVN001) to treat dry eye disease that hasn't improved enough with artificial tears. It may help people with moderate-to-severe dry eye and low tear production.
Shanghai, Shanghai MunicipalityAges 30–80 - NCT07659626Recruiting
Long-term effects of Acoltremon for dry eye disease
This study tests a new medication called Acoltremon to see if it helps dry eye symptoms over a long period. If you've had dry eye for a while and used artificial tears, this trial might be for you.
Louisville, KentuckyAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,904 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.