Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3132
- Phase 2121
- Phase 1121
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California142
- Arizona65
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT02077894Recruiting
Genetic testing to help identify inherited eye conditions
This study uses whole exome and whole genome genetic tests to look for DNA changes linked to inherited or congenital eye problems. It may help families and doctors better understand the cause of the eye condition and guide future care.
Bethesda, MarylandAges 1 day–120 years - NCT01432847Recruiting
Collecting eye-related samples to study eye diseases
This study collects samples like blood and a small skin biopsy (and sometimes urine, hair, or saliva) to better understand causes of eye diseases. The goal is to study eye conditions and may help researchers build better tests or treatments.
Bethesda, MarylandAges 1 day–120 years - NCT00001373Recruiting
Understanding the genetics of autoinflammatory diseases
This study collects genetic samples and medical histories from people with autoinflammatory diseases (like Familial Mediterranean Fever), their relatives, and healthy volunteers to understand how these conditions run in families and what causes them. Participation mainly involves providing a mail-in DNA sample.
Washington D.C., District of ColumbiaAges 2 months–115 years - NCT06967051Recruiting
Smartphone test of pupil response after cannabis use
This study uses a smartphone app to measure how your pupils react to light after using cannabis. It aims to see if the app can detect recent cannabis use, which could help develop a quick, non-invasive test.
London, OntarioAges 21 years+ - NCT05986864RecruitingPhase 1/Phase 2
Gene therapy injection for wet AMD
This study tests a new gene therapy injection called SKG0106 for people with wet AMD. The treatment is given as an injection into the eye and aims to reduce the need for frequent anti-VEGF shots.
St. Petersburg, FloridaAges 50 years+ - NCT07790211RecruitingPhase 4
Eye drop for tear film stability
This study tests an eye drop to help stabilize the natural tear film on the surface of the eye. It may help people who have normal tear production but could benefit from better tear film stability.
Sioux Falls, South DakotaAges 18 years+ - NCT07404111RecruitingPhase 1/Phase 2
Study of VV-14305 for thyroid eye disease
This study tests an investigational medication for thyroid eye disease, which causes bulging eyes and discomfort. The treatment is given as an injection near the eye, and the study will last about 12 months to see how safe and effective it is.
Livonia, MichiganAges 18–80 - NCT06882356Recruiting
AI eye screening for diabetic retinopathy
This study uses an AI-based system to check for diabetic retinopathy during regular eye exams at primary care clinics. It may help catch vision problems early if you have diabetes.
Boston, MassachusettsAges 40 years+ - NCT07790185RecruitingPhase 4
LASIK for nearsightedness: measuring vision and satisfaction
This study tests how well a new type of LASIK (called ray-tracing-guided) improves vision in low light and how satisfied patients are with the results. It is for people with mild to moderate nearsightedness who want to stop wearing glasses or contacts.
Sioux Falls, South DakotaAges 18–45 - NCT07592273RecruitingPhase 2/Phase 3
Gene therapy for diabetic eye disease without macular swelling
This trial tests a gene therapy injection into the eye to treat diabetic retinopathy (eye damage from diabetes) before it progresses. The goal is to slow or prevent vision loss and potentially delay the need for laser treatment or other injections.
Phoenix, ArizonaAges 18 years+ - NCT07734064RecruitingPhase 1
Safety of one eye injection for Stargardt vision loss
This study tests a single injection of ASP2020 in the eye to see if it is safe and if it can help improve vision for people with Stargardt disease or similar inherited eye conditions.
Phoenix, ArizonaAges 6 years+ - NCT07404865RecruitingPhase 3
Telitacicept for active primary Sjögren's disease
This study tests an investigational drug called telitacicept for people with active primary Sjögren's disease. The goal is to see if it can reduce symptoms like joint pain, fatigue, and swelling better than a placebo.
Chandler, ArizonaAges 18–75 - NCT07484555Recruiting
Posture rehab for vision problems in forward head posture
This study tests whether special posture exercises can improve mild vision problems in people with forward head posture. It may help if you're a young adult with this posture and some blurry vision.
Islamabad, CapitalAges 18–30 - NCT07499791RecruitingPhase 2
Absorbable stent for recurrent tear duct infection
This trial tests a new type of dissolvable stent that slowly releases medicine to treat chronic tear duct infections that have come back after previous surgery. It may help people who need another treatment option.
Beijing, Beijing MunicipalityAges 18–65 - NCT07174687RecruitingPhase 2
SGLT2 inhibitor for geographic atrophy
This study tests an SGLT2 inhibitor (dapagliflozin) as a possible treatment for geographic atrophy, a progressive form of dry age-related macular degeneration that causes vision loss. It is for people who meet specific eye and health criteria.
St Louis, MissouriAges 50 years+ - NCT06659445RecruitingPhase 2
Study of ONL1204 for geographic atrophy in dry AMD
This study tests an investigational medicine called ONL1204 given as an injection into the eye for people with a form of advanced dry age-related macular degeneration called geographic atrophy. The goal is to see if it can slow vision loss.
Gilbert, ArizonaAges 55 years+ - NCT07338461Recruiting
High-resolution eye imaging study for healthy and eye disease volunteers
This study uses a special, high-resolution camera to take detailed pictures of the back of the eye. It is testing the camera's ability to see changes in the retina for people who are healthy or have age-related macular degeneration, diabetic retinopathy, or other conditions that affect autofluorescence patterns.
MilanAges 18 years+ - NCT05856786Recruiting
Study how eye focusing surgery changes OCT measurements
This study looks at how refractive (vision-focusing) surgery affects OCT test images inside the eye. It may help doctors measure and track eye changes more accurately after surgery.
Omaha, NebraskaAges 19 years+ - NCT07419334RecruitingPhase 3
Study of a new drug for Stargardt disease
This trial tests a new drug, ALK-001, to see if it can slow down vision loss from Stargardt disease. It is for people who have a confirmed genetic diagnosis and are between 8 and 45 years old.
Phoenix, ArizonaAges 8–45 - NCT06662162Recruiting
Microcurrent therapy for dry age-related macular degeneration
This trial tests a new type of electrical stimulation, called microcurrent therapy, to see if it can help people with a certain form of age-related macular degeneration (AMD) that is not the "wet" kind. The treatment is delivered through an eye patch-like device and may slow vision loss or improve function.
Poway, CaliforniaAges 60 years+ - NCT07721714RecruitingPhase 4
Comparing two types of laser eye surgery for nearsightedness
This trial compares two laser vision correction methods: SMILE surgery in one eye and LASIK surgery in the other eye. It is designed for people with mild to moderate nearsightedness and astigmatism to see which approach works better.
Palo Alto, CaliforniaAges 22–59 - NCT06933693Recruiting
Exploring How We Find Objects in Visual Searches
This study compares different types of visual search tasks to learn how people find objects. You will complete four unique tasks on a computer to see how your brain processes visual information.
Boston, MassachusettsAges 18 years+ - NCT07784842Recruiting
Comparing two eye muscle surgeries for large outward deviation
This study compares two surgical techniques for correcting large-angle outward eye deviation (exotropia). It aims to see which method is more effective and better maintains eye alignment when looking sideways.
Minya, Minya GovernorateAges Any age - NCT07780916Recruiting
Long-term results of trabectome surgery for glaucoma
This study looks at the long-term results of a specific glaucoma surgery (trabectome) done at one hospital. If you had this surgery there between 2019 and 2021, researchers want to check your eye health now to see how well it worked.
Würzburg, BavariaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,904 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.