Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07739784Recruiting
Personality and side effects of glaucoma eye drops
This study looks at whether your personality affects how you experience side effects from glaucoma eye drops. The results may help doctors choose the best treatment for you and provide more personalized care.
Montreal, QuebecAges 18 years+ - NCT07738874Recruiting
Eye imaging study for premature infants at risk of retinopathy
This study looks at the tiny blood vessels in the back of the eye (retina) of premature infants who are at risk for retinopathy of prematurity, a condition that can harm vision. It aims to improve care and monitoring by using advanced eye imaging to see more detail than current methods.
Durham, North CarolinaAges birth–9 months - NCT07734064RecruitingPhase 1
Safety of one eye injection for Stargardt vision loss
This study tests a single injection of ASP2020 in the eye to see if it is safe and if it can help improve vision for people with Stargardt disease or similar inherited eye conditions.
Phoenix, ArizonaAges 6 years+ - NCT07737743RecruitingPhase 2
Testing DDY391 for Sjögren's disease
This study tests an experimental drug called DDY391 for people with Sjögren's disease. The goal is to see if it can reduce symptoms and improve quality of life, and to check for side effects.
Clearwater, FloridaAges 18–100 - NCT07734844RecruitingPhase 3
New vs existing treatment for diabetic macular edema
This study compares a new medication, tabirafusp tedromer, to an existing treatment, aflibercept, for people with diabetic macular edema (swelling in the back of the eye from diabetes). It may help if your DME hasn't improved or you're looking for a new option.
Glendale, CaliforniaAges 18 years+ - NCT06625749Recruiting
AccuraSee lens implant to improve near vision after cataract surgery
This trial tests an artificial lens (AccuraSee IOPCL) placed inside your eye to help you see better up close and at intermediate distances after having cataract surgery. It is for people who still need reading glasses and have a specific type of monofocal lens already in their eye.
Cleveland, OhioAges 22 years+ - NCT06624826Recruiting
Extended depth of focus lens for cataract surgery
This study tests a new type of lens implant that helps you see clearly at multiple distances after cataract surgery. It compares two ways to set the lens: one aiming for perfect distance vision in both eyes, and another that leaves one eye slightly nearsighted to improve reading vision.
Vienna, AustriaAges 21–105 - NCT07729137RecruitingPhase 2
Eye cell therapy for corneal swelling
This trial tests an investigational cell therapy called EO2002 for people with corneal edema (swelling of the clear front part of the eye) caused by endothelial dysfunction, which can happen with Fuchs dystrophy or after cataract surgery. The treatment aims to restore the inner layer of the cornea to reduce swelling and improve vision.
Torrance, CaliforniaAges 21 years+ - NCT07731984Recruiting
Comparing two eye measurement methods in silicone oil eyes
This study compares two ways to measure eye length in people having surgery for retinal detachment with silicone oil. The goal is to find out which measurement method works better for eyes filled with silicone oil.
SohagAges 18–70 - NCT07732010RecruitingPhase 4
Tryptophan for dry eye disease
This trial tests whether a dietary supplement called TRYPTYR can improve dry eye symptoms. You may qualify if you have moderate dry eye with certain signs, like short tear breakup time and staining on your eye surface.
New York, New YorkAges 18 years+ - NCT07729982Recruiting
Study tracking vision changes in OPA1 optic atrophy
This study follows people with a genetic form of optic atrophy over time to understand how vision changes. It does not test a treatment but helps doctors learn more about the condition to improve care.
Munich, BavariaAges Any age - NCT05832723Recruiting
Red light eye therapy for children with mild focusing error
This study tests whether low-intensity red light at 650 nm can help children and teens with mild problems focusing their eyes. It is designed to see if the treatment is safe and useful for the right type of refractive error.
Beijing, Beijing MunicipalityAges 7–18 - NCT07722546RecruitingPhase 2
Felzartamab for Graves' disease in adults
This study tests an investigational drug called felzartamab to see if it can help control thyroid function in adults with Graves' disease. It may offer a new option if you are still having symptoms despite anti-thyroid medication.
Glendale, ArizonaAges 18–75 - NCT07715695Enrolling by invitation
Coping with vision loss: an educational program
This trial tests a scalable educational program to help people adjust and cope with vision loss. It's for those who have visited a low-vision rehabilitation clinic and can engage with the audiovisual materials.
Boston, MassachusettsAges 18–89 - NCT07722910Recruiting
Iris blood flow in diabetic neovascular glaucoma
This study uses a special camera (OCTA) to look at blood flow in the iris of people with or without type 2 diabetes and diabetic neovascular glaucoma. The goal is to understand how blood flow changes in this eye condition.
Jinan, ShandongAges 18 years+ - NCT07721779Recruiting
Steam mask vs. warm compresses for kids' eyelid lumps
This trial tests whether a special steam mask helps treat chalazion (a small lump on the eyelid) in children, compared to the usual warm compress. It's a simple home treatment that may be easier and more effective for kids.
SheffieldAges 5–16 - NCT07716397Recruiting
MRI study for thyroid eye disease diagnosis and care
This study uses MRI scans of the eye area to better understand and classify thyroid eye disease (TED). It aims to help doctors predict outcomes and personalize treatment. You may be eligible if you have stable TED or are a healthy volunteer.
Shanghai, Huangpu DistrictAges 18–75 - NCT07721714RecruitingPhase 4
Comparing two types of laser eye surgery for nearsightedness
This trial compares two laser vision correction methods: SMILE surgery in one eye and LASIK surgery in the other eye. It is designed for people with mild to moderate nearsightedness and astigmatism to see which approach works better.
Palo Alto, CaliforniaAges 22–59 - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT07715864RecruitingPhase 2
Cannabis compounds for brain protection after concussion
This trial tests whether natural cannabis compounds can help protect the brain after a concussion in male contact-sport athletes. It requires you to be healthy, not a regular cannabis user, and free of certain medical conditions.
Regina, SaskatchewanAges 19–35 - NCT07722247Recruiting
Eye stiffness and healing in cataract surgery with PEX
This study looks at how your eye's outer layer (cornea) heals and changes shape after cataract surgery, specifically comparing people who have pseudoexfoliation syndrome (PEX) with those who do not. The goal is to see if PEX affects the final vision result after cataract removal.
Split, Splitsko-dalmatinska CountyAges 50–85 - NCT05278715RecruitingPhase 2
New treatment plan for optic pathway glioma in children
This Phase 2 trial tests a modified chemotherapy treatment plan for children and young people with optic pathway glioma, aiming to shrink tumor and improve eye/brain symptoms. You may be able to join if your diagnosis is confirmed and your body can safely handle treatment.
BeijingAges 3 months–21 years - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06054542Recruiting
Digital eye strain questionnaire Turkish study
This study tests a Turkish version of a questionnaire about digital eye strain. It is for people aged 18–65 who use digital devices for at least two hours a day.
AntalyaAges 18–65
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.