Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT06753916RecruitingPhase 2
Trial of a new treatment for high-risk cornea transplants
This study tests a new approach to help prevent cornea transplant failure in people with high-risk conditions, such as blood vessels growing into the cornea. It aims to see if this treatment can improve transplant success.
Irvine, CaliforniaAges 18 years+ - NCT07713979Recruiting
VisionWay Accessibility study for people with vision loss
This study tests a new system called VisionWay to help people with severe vision loss or blindness navigate safely. Researchers want to see if it works better than a cane or guide dog alone.
Orono, MaineAges 18 years+ - NCT07711561RecruitingPhase 1
Cell therapy for cornea swelling after cataract surgery
This trial tests a simple cell treatment for a swollen cornea caused by cataract surgery. It aims to help your cornea become clear again without a full transplant.
Hyderabad, TelanganaAges 18–80 - NCT07708740Recruiting
Two doses of ketamine for preventing slow heart rate during eye surgery
This study tests whether two doses of ketamine (a medicine given through a vein) can reduce a reflex that slows the heart during eye surgery. If you are having eye surgery that involves moving the eye muscles, you may be eligible.
CairoAges 18–65 - NCT07708142RecruitingPhase 3
Testing a new injection for swelling after retinal vein blockage
This trial tests a new medicine called SMO1 for people with vision loss and swelling in the eye caused by a blocked vein in the retina. It involves regular eye injections to see if the medicine can reduce swelling and improve vision.
Seoul, Gangdong-guAges 19 years+ - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT06708260RecruitingPhase 2
Study of ENN0403 for diabetic macular edema
This trial tests a new eye drop or injection called ENN0403 for people with diabetic macular edema (swelling in the back of the eye due to diabetes). The goal is to see if it can improve vision and reduce swelling.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07688538Recruiting
Mapping vision system development in embryos
This trial studies embryos to understand how the visual system develops normally and abnormally. It compares tissues from embryos with developmental problems to healthy ones, aiming to create a detailed map of early vision system growth.
Guangzhou, GuangdongAges Any age - NCT07241169RecruitingEarly Phase 1
Gene therapy trial for ABCA4-related retinal disease
This trial tests a new gene therapy called ZVS106e for people with inherited retinal degeneration caused by changes in both copies of the ABCA4 gene. The therapy aims to slow or stop vision loss, and the study will check if it is safe and if it works.
Beijing, Beijing MunicipalityAges 8 years+ - NCT07675616Recruiting
Comparing two drugs for numbing the eye before tear-duct surgery
This trial tests whether adding dexmedetomidine or magnesium sulfate to lidocaine makes numbing the eye more effective for tear-duct surgery. The goal is to find which combination provides better pain control during surgery.
CairoAges 18 years+ - NCT07516132RecruitingPhase 3
Long-term safety study of axitinib implant for wet macular degeneration
This study follows people who completed an earlier 2-year trial of OTX-TKI, a small implant placed in the eye to treat wet age-related macular degeneration (a condition causing vision loss). Researchers want to make sure the treatment remains safe over time.
Bakersfield, CaliforniaAges 50 years+ - NCT06474442RecruitingPhase 2
BD111 gene therapy for herpes simplex virus eye infection
This trial tests a new gene therapy called BD111 for people with a herpes simplex virus infection in the cornea (the clear front part of the eye). It aims to see if the treatment is safe and can help clear the virus, possibly improving vision.
Wenzhou, ZhejiangAges 18–70 - NCT04600570Recruiting
Ultrasound measurement of the eye nerve in adults
This study uses an ultrasound scan to measure the space around the optic nerve in healthy adults. It helps researchers better understand normal ultrasound measurements for comparison in future eye or brain-related conditions.
TaipeiAges 20 years+ - NCT04591483Recruiting
Test study for ELOVL4-related Stargardt-like vision loss
This trial is for people with a specific genetic cause of Stargardt-like macular dystrophy due to ELOVL4 mutations. It uses regular eye tests and imaging to see how the condition is affected and whether the study approach might help.
Bethesda, MarylandAges 10–100 - NCT07489131RecruitingPhase 3
Comparing a new macular edema treatment to Eylea HD
This study tests whether a new drug (AVT29) is as safe and effective as the standard treatment Eylea HD for people with diabetic macular edema (DME) — a condition where fluid builds up in the back of the eye due to diabetes. If you have vision loss from DME and haven't had anti-VEGF injections before, you may be able to join.
BudapestAges 18 years+ - NCT06999733RecruitingPhase 1/Phase 2
Testing KB801 for stage 2 or 3 neurotrophic keratitis
This trial tests whether KB801 can help heal persistent corneal defects better than a placebo. It is for people with neurotrophic keratitis (a condition where the cornea loses sensation) that has not improved with standard care.
Irvine, CaliforniaAges 18 years+ - NCT05476523Recruiting
Eye-tracking tests for adults to study vision and brain signals
This trial uses an eye-tracking camera or software to measure how your eyes move while you do simple tasks. It’s meant to test whether the eye-tracking system can reliably collect useful movement data in people like you.
Wilmington, DelawareAges 18–90 - NCT07691463Recruiting
How light-sensitive cells help your eye focus
This trial studies how different types of light-sensitive cells in your eye work to help you focus. It involves sitting still and looking at lights while measurements are taken.
Rochester, New YorkAges Up to 35 years - NCT07462897Recruiting
New lens to slow nearsightedness in children
This trial tests a special eyeglass lens designed to slow down the worsening of nearsightedness (myopia) in children ages 6 to 14. It aims to keep their eyesight from getting worse quickly.
ParisAges 6–14 - NCT06141460RecruitingPhase 1/Phase 2
Gene therapy trial for wet age-related macular degeneration
This trial tests a new gene therapy called RRG001 for people with the 'wet' form of age-related macular degeneration. It aims to treat leaky blood vessels in the eye that can cause vision loss, possibly reducing the need for frequent eye injections.
Tianjin, Tianjin MunicipalityAges 50 years+ - NCT07456488RecruitingPhase 2
Atropine eye drops for nearsighted children
This study tests if low-dose atropine eye drops can slow down worsening nearsightedness in children. Children in the study receive either the drops or no treatment, and their vision changes are tracked over time.
Karachi, SindhAges 4–16 - NCT06454955RecruitingEarly Phase 1
PET scan imaging study for solid tumors using a new probe
This trial tests a new imaging agent that targets a protein called B7-H3 found on many solid tumors. It uses PET/CT to help doctors see and stage tumors more clearly.
Beijing, Beijing MunicipalityAges 18–75 - NCT07120178Recruiting
Imaging and outlook for colored eye growths in children
This study looks at how colored growths on the front of the eye (called pigmented tumors) are imaged and how they change over time in children. Researchers want to understand these growths better to improve care.
Saint-EtienneAges Up to 18 years - NCT06975748RecruitingPhase 2
Eye Drop for Nerve-Damaged Corneas
This trial tests an experimental eye drop (STSP-0902) for a condition called neurotrophic keratitis, where the cornea (the clear front part of the eye) gets scratches or sores because nerves are damaged. The drop contains a growth factor to help the eye heal. You might be eligible if you have a persistent scratch or sore on your cornea that has not improved for at least a week.
Jinan, ShandongAges 18–85
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.