Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT06755060Recruiting
AI-assisted eye care study
This trial tests how artificial intelligence can help doctors make better decisions about eye diseases. It may be a good fit if you have an eye condition and can share your medical records and images.
Zhuhai, GuangdongAges Any age - NCT07695207RecruitingPhase 3
Testing SMZ1 with ranibizumab for wet macular degeneration
This trial tests a new medicine called SMZ1 combined with ranibizumab (a standard treatment) for people with wet macular degeneration. It may help improve vision by targeting the cause of the disease more effectively.
Seoul, SeoulAges 50 years+ - NCT07695298RecruitingPhase 4
Testing faricimab for a rare eye disease linked to histoplasmosis
This trial tests a drug called faricimab (brand name Vabysmo) for treating abnormal blood vessel growth in the back of the eye, caused by a past infection with histoplasmosis. The goal is to see if it helps improve vision over 52 weeks.
Cincinnati, OhioAges 18 years+ - NCT07208838Enrolling by invitation
Testing a new digital eye chart for vision in Bulgaria
This study checks if a new digital eye chart (DDIVAT) works as well as traditional paper charts for measuring distance vision. It includes Bulgarian-speaking adults and healthy volunteers.
PlovdivAges 18 years+ - NCT07053358RecruitingEarly Phase 1
Gene therapy for wet AMD
This trial tests a new gene therapy (LX111) for people with wet age-related macular degeneration (AMD) who have already been helped by standard anti-VEGF injections. The goal is to see if one dose of LX111 can reduce the need for frequent eye injections.
ShanghaiAges 50 years+ - NCT05797298Recruiting
Toric lens implant surgery for cataracts
This trial studies implanting a special “toric” lens to improve vision for people with cataracts. It may help reduce the need for glasses for some people, depending on their eye measurements.
Shanghai, ChinaAges Any age - NCT06503276RecruitingPhase 2
Orelabrutinib and radiation for a type of eye lymphoma
This trial tests a combination of a targeted drug (Orelabrutinib) and radiation therapy for adults newly diagnosed with a slow-growing lymphoma around the eye. The goal is to see if this approach works well and is safe for people who have not had treatment before.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07189169RecruitingPhase 3
Testing QA108 for intermediate AMD
This trial tests an investigational medicine (QA108) for people with intermediate age-related macular degeneration (AMD). It aims to slow or prevent progression of the disease by treating the deposits (drusen) in the center of the retina.
BeijingAges 45–85 - NCT07561398RecruitingPhase 4
Insulin drops vs amniotic membrane for stubborn corneal sores
This trial compares two treatments for persistent corneal surface wounds that haven't healed with standard care. You'll receive either insulin eye drops or a special tissue graft to help your cornea heal.
Rawalpindi, Punjab ProvinceAges 16–70 - NCT07154121Recruiting
5-FU added to tear duct surgery for small tear sacs
This study tests if adding a medicine called 5-FU to standard tear duct surgery helps people with a small tear drainage sac get better results. It might be an option if you have a blocked tear duct and a very small sac.
Guangzhou, GuangdongAges 18 years+ - NCT07084545Recruiting
Cataract surgery lens for people with prior laser vision correction
This trial tests a special lens (CT LUCIA) for people who had laser vision correction in the past and now need cataract surgery. It aims to see how well the lens works in these patients.
Sugar Land, TexasAges 18 years+ - NCT07571330Recruiting
Upper Tear Drain Plug for Dry Eye After Lower Plug
This trial tests whether adding a plug to your upper tear drain (in addition to an existing lower plug) helps severe dry eye. It may improve comfort by reducing tear loss.
Monterrey, Nuevo LeónAges 18 years+ - NCT07568730RecruitingPhase 2
Testing Lacripep eye drops for neurotrophic keratitis
This trial tests whether a new eye drop called Lacripep can help treat neurotrophic keratitis, a rare eye condition where the cornea loses sensation and can become damaged. The study compares Lacripep to a placebo (inactive) drop to see if it improves corneal healing and vision.
Carmel, IndianaAges 18 years+ - NCT07081139Recruiting
Visual screening study for children with special needs
This study uses a video-based eye-tracking system to test how well children with special needs and typical preschoolers can see. It aims to find a friendly way to screen vision without asking children to read letters.
TaipeiAges birth–70 years - NCT07458061RecruitingPhase 1/Phase 2
Kamuvudine-9 for diabetic macular edema
This trial tests a new drug, Kamuvudine-9 (K9), to treat diabetic macular edema (swelling in the back of the eye caused by diabetes). It may help improve vision in people with diabetes who have not yet needed major treatments.
Roanoke, VirginiaAges 18 years+ - NCT06718816Recruiting
Long-term follow-up of AL-001 eye injection for wet AMD
This trial is a long-term follow-up for people who already received the AL-001 eye injection for wet age-related macular degeneration (wet AMD) in an earlier study. It will check how you are doing over time.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07549711Enrolling by invitation
Understanding Long Anterior Zonule Eye Condition and Genes
This research study examines a rare eye condition called long anterior zonule (LAZ) that affects the structures supporting the lens. Researchers will compare people with this condition to those without it, and study families where LAZ runs in the family, to understand how genes and physical eye changes relate to this condition.
Fuzhou, FujianAges 18 years+ - NCT07566234Recruiting
Contact Lenses and Myopia Study for Children
This study tests whether special contact lenses can help slow down nearsightedness (myopia) in children ages 8–10. Researchers want to see if wearing these lenses daily can help your child's eyes develop more normally and reduce the need for stronger glasses over time.
ShanghaiAges 8–10 - NCT05828251Recruiting
Treating a fresh macular hole sooner or later
This study looks at how to manage a full-thickness macular hole that started recently, comparing different timing (“subacute” care) to see which approach helps vision best. You may be considered if your hole is small and new, and you can follow required eye positioning after treatment.
Glostrup Municipality, CopenhagenAges 18 years+ - NCT07539831Recruiting
Menstrual cycle effects during minimally invasive gynecology surgery
This study examines how the menstrual cycle may affect pressure in the optic nerve (the nerve connected to your eye) during laparoscopic gynecologic surgery. Researchers want to understand if the timing of surgery within your cycle matters for eye and brain safety.
KonyaAges 18–45 - NCT06077253Recruiting
Preventing angle closure glaucoma in Danish patients
This trial tests a laser treatment to prevent a type of glaucoma called angle closure. It is for people who have a narrow drainage angle in the eye but do not yet have glaucoma or other serious eye conditions.
AalborgAges 40–80 - NCT06035887Recruiting
New eye test for hydroxychloroquine damage
This trial tests a new type of eye test (ERG) to detect early damage from hydroxychloroquine, a drug used for conditions like lupus and rheumatoid arthritis. If you take hydroxychloroquine or have never taken it, you might help find better ways to protect your vision.
London, LondonAges 18 years+ - NCT07535749RecruitingPhase 3
Contact Lenses to Slow Nearsightedness in Chinese Children
This study tests special contact lenses designed to slow the progression of nearsightedness (myopia) in Chinese children. If the lenses work as hoped, they could help reduce how quickly a child's eyesight worsens over time.
AucklandAges 7–11 - NCT07595432Recruiting
Vision Technique for Cataract Lens Implant Patients
This study tests a new way to measure and optimize vision in patients who have already had cataract surgery with a lens implant. Researchers want to see if this technique helps patients see as clearly as possible.
ManilaAges 21 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.