Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,764 recruiting studies in this area right now.
By phase
- Not applicable1,204
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- National Taiwan University Hospital16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona68
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,764 total
- NCT07758582Recruiting
Artificial intelligence for detecting diabetic retinopathy from eye photos
This study tests an AI system that automatically detects signs of diabetic retinopathy from eye photos. It aims to see if the AI can accurately identify these signs to help with early detection.
AlexandroupoliAges 18 years+ - NCT07761949Recruiting
How streetscape views affect children's perception
This study uses eye-tracking glasses to see how children with and without myopia (nearsightedness) look at outdoor scenes from streets and neighborhoods. The results may help design environments that support healthy vision in children.
Guangzhou, GuangdongAges 6–18 - NCT06487897RecruitingPhase 3
Presbyopia correction with the VIS Opti-K system
This trial tests a new treatment called the VIS Opti-K™ System to help people with presbyopia (age-related trouble seeing up close) see better without glasses. It uses a special lens to improve near vision in one eye while keeping distance vision clear.
Boca Raton, FloridaAges 40 years+ - NCT05888987Recruiting
New test for severe corneal infection diagnosis
This study tests a new method for identifying bacteria causing severe corneal infections. It may help doctors choose the right treatment faster by improving how the infection is identified from corneal samples.
ReimsAges 18 years+ - NCT07756385Recruiting
Comparing two cataract surgery systems
This study compares two different machines used for cataract surgery (phacoemulsification) to see if one is better. If you're having cataract surgery on both eyes, this trial might help improve your treatment.
ZagrebAges 18 years+ - NCT07755748Recruiting
Glaucoma screening survey response study
This study tests different ways to encourage people to respond to a survey about glaucoma screening. It aims to improve how we reach and screen people at risk for glaucoma in California.
Oakland, CaliforniaAges 50 years+ - NCT07752433Recruiting
Combining brain stimulation and eye exercises for adult lazy eye
This study combines two non-invasive treatments for adult lazy eye (amblyopia): gentle brain stimulation and a special eye exercise using augmented reality. The goal is to improve vision in the weaker eye, offering a non-surgical option for adults with this condition.
Coimbra, Coimbra DistrictAges 18–40 - NCT07755761Recruiting
Tube surgery for hard-to-treat glaucoma
This study tests a new tube-based surgery to lower eye pressure in people with advanced or difficult-to-treat open-angle glaucoma. The goal is to see if this surgery works better than standard care for controlling pressure and preserving vision.
BanhāAges 18 years+ - NCT07753603RecruitingPhase 3
Linsitinib for active moderate to severe thyroid eye disease
This study tests an experimental pill (linsitinib) for people with active thyroid eye disease. Participation may help reduce eye bulging and other symptoms, especially if other treatments haven't worked.
Las Vegas, NevadaAges 18 years+ - NCT06474520Recruiting
Bovine gallstone extract for inflammatory brain disease
This trial tests a natural substance called Calculus Bovis Sativus (CBS) to see if it helps people with certain inflammatory brain conditions like multiple sclerosis, neuromyelitis optica, MOGAD, or ADEM. The goal is to find out if it is safe and effective.
Wuhan, HubeiAges 18 years+ - NCT06394232RecruitingPhase 1/Phase 2
Testing a cell therapy for advanced dry AMD with geographic atrophy
This trial tests a new treatment called Eyecyte-RPE™, made from special cells that support the retina. It is given as a single injection under the retina during eye surgery. The study aims to see if it can help people with advanced dry age-related macular degeneration (AMD) who have large areas of damage (geographic atrophy) in the center of their vision.
Jālna, MaharashtraAges 50–100 - NCT07748936Recruiting
Eye imaging and blood vessel changes in ultra-trail runners
This study looks at how the back of the eye (retina and blood vessels) changes in people doing an ultra-trail race. It compares them to active people who are not doing the race, to see if intense running affects eye health.
DijonAges 18 years+ - NCT07746752Recruiting
School program to prevent nearsightedness in kids with good eye reserve
This study tests whether a school-based program can help prevent nearsightedness (myopia) in children who currently have good distance vision and enough 'eye reserve' (hyperopic reserve) to potentially avoid becoming nearsighted. It focuses on early elementary students to see if simple activities can keep their eyes healthy.
Shanghai, Shanghai MunicipalityAges 6–11 - NCT07746778Recruiting
School program to slow nearsightedness in children
This study tests whether a school-based program can help slow the progression of nearsightedness (myopia) in children who are either already nearsighted or at risk of becoming nearsighted. It may help reduce the need for stronger glasses in the future.
Shanghai, Shanghai MunicipalityAges 6–11 - NCT07746804Recruiting
School program to prevent nearsightedness in children
This study tests a school-based program to help prevent nearsightedness (myopia) in children who are not yet nearsighted but have a higher risk of developing it. It uses a simple, non-invasive method called auricular acupressure, which involves placing small seeds on the ear, to see if it can keep eyes healthy and reduce the chance of needing glasses.
Shanghai, Shanghai MunicipalityAges 6–11 - NCT07747428Recruiting
Eye imaging study for diabetic retinopathy
This study uses a special eye imaging test called OCT angiography to look at tiny blood vessels in the back of the eye. It aims to understand changes caused by diabetic retinopathy, which could help improve how we monitor and treat this condition.
SohagAges 18–80 - NCT07747662Enrolling by invitation
Eye imaging study for early geographic atrophy
This study uses special eye imaging to look closely at areas of damage in the back of the eye (geographic atrophy) caused by age-related macular degeneration. It will help doctors understand early-stage disease better and may guide future treatments.
Madison, WisconsinAges 50 years+ - NCT07745062RecruitingPhase 4
Comparing two eye drops for mild to moderate dry eye
This study tests two types of preservative-free eye drops to see which is more effective for people with mild to moderate dry eye disease. You will use one of the drops as directed, and the study will monitor your symptoms and eye health over time.
La Jolla, CaliforniaAges 18 years+ - NCT03131726RecruitingPhase 3
Simvastatin for Graves eye disease in mild-to-moderate cases
This trial tests whether simvastatin (a cholesterol medicine) can improve eye symptoms from Graves’ eye disease. It is aimed at people with active mild-to-moderate disease and will also check safety with blood tests, heart/skin tolerance, and stomach health.
MalmöAges 18–70 - NCT06613555Recruiting
Eye blood vessel scan study for systemic disease
This study uses an advanced eye scan (OCT-A) to look at tiny blood vessels in the back of the eye. It compares people with systemic blood vessel conditions (like high blood pressure or inflammatory disease) to healthy volunteers, to see if the eye scan can help predict or understand these diseases.
DijonAges 18 years+ - NCT06522867Recruiting
Measuring eye pressure after vitreoretinal surgery
This study compares three different devices (Goldmann, Icare, and Accupen) to measure eye pressure after vitreoretinal surgery. It aims to find the most accurate and comfortable method for patients.
Québec, QuebecAges 18 years+ - NCT03063216Recruiting
Study of treatment outcomes for children with cataracts
This study looks at children who have cataracts (clouding of the eye lens) and how well treatments and eye care go. You may be able to take part if your child can cooperate with eye exams and does not have certain mental or learning conditions that affect participation.
Shanghai, Shanghai MunicipalityAges 2 months–20 years - NCT07732855Recruiting
Treating eye surface inflammation
This study tests a treatment for inflammation on the eye's surface, specifically keratitis (cornea inflammation), to see if it can help calm the redness, pain, or irritation.
Budapest, Pest CountyAges 4–60 - NCT07740590Recruiting
Comparing artificial lenses for cataract surgery and quality of life
This study compares different types of artificial lenses (IOLs) placed during cataract surgery to see which helps your eyes adapt and improves your quality of life best. It is for people having cataract surgery on both eyes who have very little natural corneal curve (astigmatism).
ChengduAges 18–100
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,764 recruiting ophthalmology studies from the U.S. registry right now, out of 2,747 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.