Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07502456Recruiting
Clareon TruPlus study for cataract patients with astigmatism
This trial tests a new type of lens (toric IOL) to correct both cataracts and astigmatism in one surgery. It may help you see clearly without glasses if you have cataracts and a mild to moderate astigmatism.
Phoenix, ArizonaAges 22 years+ - NCT06491693Recruiting
Can eye nerve test predict brain complications after carotid surgery?
This trial checks if measuring the nerve sheath in your eye can help doctors predict brain-related problems after carotid artery surgery. It aims to improve safety during the procedure.
IstanbulAges 50–80 - NCT06375239Recruiting
Study of tests for tracking vision in retinal disease
This study will check if certain vision tests work well in people with retinal diseases like retinitis pigmentosa or Stargardt. Results will help design future trials.
Irvine, CaliforniaAges 18 years+ - NCT07505264Recruiting
Comparing two laser platforms for myopia surgery
This trial tests if a newer laser machine (VISUMAX 800) works as well as the current standard (VISUMAX 500) for correcting nearsightedness. It may help decide if the newer technology offers better outcomes for patients.
SingaporeAges 21 years+ - NCT07501117RecruitingPhase 1
Immunotherapy before eye removal for high-risk eye melanoma
This trial tests immunotherapy before surgery for people with high-risk eye melanoma (uveal melanoma). You’ll get treatment to help your immune system fight the cancer, then have your eye removed. After surgery, you’ll be followed to see how well the treatment worked.
Herlev, HerlevAges 18–80 - NCT07502378RecruitingPhase 4
Eye drops for dry eye in early neurotrophic keratopathy
This trial tests a new eye drop (acoltrepon) to see if it helps people with stage 1 neurotrophic keratopathy (a condition where the cornea's nerves are damaged, causing dry eyes and vision problems) and low tear production. It aims to improve signs like corneal staining and symptoms of discomfort.
Tampa, FloridaAges 18 years+ - NCT07500324Recruiting
Searching for new markers in age-related eye diseases
This study looks for proteins in the blood and eye fluids that may help doctors better understand and monitor three common eye conditions: age-related macular degeneration, diabetic retinopathy, and retinal detachment. If you have one of these conditions, or if you are a healthy control with no retinal disease, you may be able to help by giving a small sample of blood or fluid from your eye during a routine procedure.
Roma, ItalyAges 18 years+ - NCT06742268Recruiting
Extension study on a myopia treatment for children
This study is for children who already completed an earlier trial of the experimental treatment SAT-001. Researchers want to see if the treatment is safe over a longer time and if there is any rebound effect after stopping it.
Seoul, Choose One...Ages 5–8 - NCT06162013RecruitingPhase 2
NAD supplement trial for atypical parkinsonism
This trial tests whether a supplement called nicotinamide riboside (NR) can help people with rare forms of parkinsonism (PSP, MSA, or CBS). It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real supplement or a placebo.
Oslo, OsloAges 30–85 - NCT07496957Recruiting
A new glaucoma surgery: Preserflo versus trabeculectomy
This trial compares two types of glaucoma surgery to see which one works better for people with specific kinds of open-angle glaucoma whose eye pressure isn't controlled by eye drops or laser.
Bialystok, PolskaAges 21 years+ - NCT07496359Recruiting
Helping older adults with diabetes and memory concerns
This study tests a program that helps older adults with both diabetes and early memory problems, along with their caregivers, manage their health better together.
Hong KongAges 55 years+ - NCT07495852RecruitingPhase 3
Implant for eye pressure in glaucoma or ocular hypertension
This trial tests a tiny implant that slowly releases medication inside the eye to lower pressure. It is for people with open-angle glaucoma or high eye pressure who have not had certain eye surgeries.
Dothan, AlabamaAges 18 years+ - NCT07496567RecruitingPhase 2/Phase 3
Study of EYE201 for wet age-related macular degeneration
This trial tests a new medicine, EYE201, for people with wet age-related macular degeneration (AMD) that has not been treated before. The study will see if this drug can help improve vision and slow down vision loss.
Gilbert, ArizonaAges 50 years+ - NCT04733950Recruiting
Test how much effort listening takes with cochlear implants
This study measures how your brain and eyes respond when you listen and focus on sounds. It compares people using a cochlear implant with people who have normal hearing, to understand listening effort and attention.
ParisAges 18–80 - NCT06771908Recruiting
Eye drops to prevent infection after eye surgery
This trial tests if an eye drop called Zamidine® can help prevent infections in people who have a history of repeated eye infections (conjunctivitis) and are about to have eye surgery. The goal is to see if it safely reduces the risk of surgery-related eye infections.
RomeAges 18–90 - NCT04985487Recruiting
Safety follow-up for brolucizumab in neovascular AMD
This study tracks the real-world safety of brolucizumab in adults with neovascular age-related macular degeneration (nAMD). If you’re already prescribed this medicine, the study may help confirm it continues to be safe and well-tolerated over time.
Daegu, Dalseo GuAges 18–100 - NCT06601101RecruitingPhase 3
Insulin drops for faster healing after corneal crosslinking
This trial tests whether insulin eye drops can help the cornea heal faster after corneal crosslinking, a procedure to treat keratoconus. It is for people with keratoconus who do not have diabetes, severe dry eye, or certain other eye conditions.
Campinas, São PauloAges 14 years+ - NCT06774651Recruiting
Comparing two laser eye surgery methods for vision correction
This trial compares two types of laser eye surgery (CLEAR and SMILE) to see which works better for nearsightedness and astigmatism. If you are eligible, it could help find the best option for your vision.
SingaporeAges 21–50 - NCT07482176RecruitingPhase 3
Gene therapy trial for wet age-related macular degeneration
This trial tests a one-time gene therapy injection (IXO-vec) for people with wet age-related macular degeneration (nAMD). It aims to reduce the need for frequent eye injections by helping the eye make its own medicine to block the growth of harmful blood vessels.
Mesa, ArizonaAges 50 years+ - NCT07489131RecruitingPhase 3
Comparing a new macular edema treatment to Eylea HD
This study tests whether a new drug (AVT29) is as safe and effective as the standard treatment Eylea HD for people with diabetic macular edema (DME) — a condition where fluid builds up in the back of the eye due to diabetes. If you have vision loss from DME and haven't had anti-VEGF injections before, you may be able to join.
BudapestAges 18 years+ - NCT07489430RecruitingPhase 2
DaxibotulinumtoxinA for eyelid spasms
This trial tests a new botulinum toxin injection for people with disruptive eyelid spasms (blepharospasm). It may offer longer-lasting relief with potentially fewer side effects for those who currently use other botulinum toxin injections.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07484555Recruiting
Posture rehab for vision problems in forward head posture
This study tests whether special posture exercises can improve mild vision problems in people with forward head posture. It may help if you're a young adult with this posture and some blurry vision.
Islamabad, CapitalAges 18–30 - NCT07481487Recruiting
Cataract and vision correction surgery outcomes
This trial looks at results after cataract or vision correction surgery, like lasik or lens implants. It helps doctors improve care.
Bristol, EnglandAges 18 years+ - NCT07482228Recruiting
Long-term outcomes after retinal artery occlusion
This study looks at the long-term health results of people who have a retinal artery occlusion (a blockage in the blood vessels of the eye). It aims to understand what happens over time, which can help guide treatment and care.
Gwangju, GwangjuAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.