Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT04225611RecruitingPhase 1/Phase 2
Drug-delivering contact lens for recurrent macular swelling
This study tests a special contact lens that slowly delivers anti-inflammatory/steroid medicine to the back of the eye. It aims to treat cystoid macular edema that keeps coming back and may improve vision for people who respond to steroid treatment.
Boston, MassachusettsAges 18–85 - NCT04232982Recruiting
Cyclophotocoagulation during Boston keratoprosthesis eye surgery
This trial looks at whether a specific eye laser treatment done through the white of the eye (called transscleral cyclophotocoagulation) works well and is safe for people getting a Boston keratoprosthesis. It may help improve comfort and vision outcomes for selected patients needing this type of cornea/eye replacement surgery.
Montreal, QuebecAges 18–80 - NCT04240652Recruiting
Diabetes eye screening and prevention program for eye disease
This program aims to screen people for diabetic eye problems early and help prevent vision loss over time. It may help you if you have type 2 diabetes (or you’ve been invited as a diabetes/non-diabetes participant) and can safely take part in the study activities.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04251143Recruiting
Study for corneal disease and corneal thinning
This study looks at people with corneal disease, especially corneal thinning that can change how the eye focuses light. It may help researchers understand treatments and care plans for these conditions.
Dresden, SaxonyAges 18–65 - NCT04252989Recruiting
Atropine eye drops for slowing worsening nearsightedness in kids
This trial studies using low-dose atropine eye drops to help slow worsening nearsightedness (myopia) in children. It may help kids whose myopia is actively getting worse, depending on how consistently the drops are used.
Saint-EtienneAges Up to 18 years - NCT04258787Recruiting
Eye drop treatment for Fuchs corneal swelling
This trial studies a treatment for people with Fuchs’ dystrophy that affects the clear layer at the back of the cornea. It may help improve how clear your vision is after the cornea can no longer pump fluid out properly.
Portland, OregonAges 18 years+ - NCT04278131RecruitingPhase 1/Phase 2
Test eye gene therapy for retinitis pigmentosa
This Phase 1/2 study tests a gene therapy treatment (BS01) in people with retinitis pigmentosa to try to improve or preserve vision. You may be a candidate if your vision in at least one eye is quite limited and you haven’t had certain gene therapies before.
Teaneck, New JerseyAges 18 years+ - NCT04289571RecruitingPhase 1
Virtual reality vision testing for people with retinal disease
This early-stage study uses virtual reality tasks to check how well a person can move and function using their eyesight. It may help researchers measure vision abilities in a way that could guide future care for retinal disease.
Bethesda, MarylandAges 5–120 - NCT04292080RecruitingPhase 2
Tecfidera trial to slow worsening geographic atrophy
This Phase 2 study tests dimethyl fumarate (Tecfidera) to slow the growth of geographic atrophy, a form of age-related macular degeneration that affects central vision. You may be asked to take the study medicine and attend regular eye scans over about 2 years to see if it helps.
Créteil, Val De MarneAges 55–85 - NCT04310241Recruiting
Test eye alignment and vision changes in lazy eye patients
This study looks at vision problems in children with lazy eye (amblyopia) and eye misalignment (strabismus), and whether they improve with treatment. It may help researchers understand what visual changes to expect and which patients respond best.
Cleveland, OhioAges 6 months–90 years - NCT04319848RecruitingPhase 1
Tissue-engineered cornea transplant for specific eye swelling conditions
This Phase 1 trial tests a new, lab-made tissue transplant to improve corneal clarity in people with certain types of corneal endothelium failure (eye swelling) caused by specific conditions. The main goal is to check safety and see if vision and corneal health improve.
SingaporeAges 21–80 - NCT04334031Recruiting
Hospital follow-up study for immune-related disease
This is a study that follows people with an immune-related illness at Lille University Hospital to better understand their care needs over time. By collecting information regularly, the study may help improve how future patients are monitored and treated.
LilleAges 18 years+ - NCT04339764RecruitingPhase 1/Phase 2
iPS cell eye transplant for dry macular degeneration
This early-phase study tests whether transplanting lab-made retinal cells from your own body can slow vision loss from geographic atrophy caused by dry age-related macular degeneration. It involves eye surgery and frequent follow-up to check safety and early signs of benefit.
Baltimore, MarylandAges 55–95 - NCT04353960Recruiting
Study of heart rate response during eye muscle surgery
This study looks at how the heart rate changes when eye doctors move the eye muscles during strabismus (eye alignment) surgery. It may help doctors better understand and manage this normal reflex during surgery.
Anchorage, AlaskaAges 1 month–100 years - NCT04354545Recruiting
Testing treatments for eye discomfort in glaucoma
This trial studies how to treat eye surface discomfort in people who have glaucoma and are already using multiple eye drops. It may help reduce symptoms like irritation while keeping glaucoma treatment on track.
Fountain Valley, CaliforniaAges Any age - NCT04378790RecruitingPhase 3
Patch one eye by itself or together with glasses
This study tests whether children with amblyopia (lazy eye) should start patching one eye after glasses first, or start patching at the same time as glasses. The goal is to find the best approach to improve vision.
Birmingham, AlabamaAges 3–13 - NCT04396002Recruiting
Study of life movement and vision loss in older adults
This study looks at whether how far and how much you move around each day is linked to glaucoma and vision field loss in older adults. It may help researchers understand what affects vision changes over time.
Birmingham, AlabamaAges 18–100 - NCT04402086Recruiting
Rheumatology patient and skin sample registry study at Yale
This study builds a health record and blood/skin sample collection for people with rheumatic autoimmune diseases who are getting care at Yale. It may help researchers understand these conditions and develop better tests or treatments over time.
New Haven, ConnecticutAges 18–99 - NCT04416724Recruiting
Surgery versus laser for early pseudoexfoliation glaucoma
This trial compares cataract surgery (phacoemulsification) versus a laser treatment (SLT) as the first treatment for pseudoexfoliation glaucoma. It aims to find which approach lowers eye pressure and helps prevent progression for people with early disease and cataracts.
Halifax, Nova ScotiaAges 50 years+ - NCT04420156Recruiting
Study to understand eye disease risk in premature babies
This study looks at newborn eye exams and genetic information to better understand why some premature infants develop a serious vision problem called ROP. You may be invited because your baby needs routine eye screening or is being moved for specialized eye care.
Palo Alto, CaliforniaAges Up to 1 year - NCT04424719Recruiting
Follow-up study for high-risk eye melanoma after treatment
This study follows people with high-risk uveal (eye) melanoma after their initial treatment to better understand relapse risk. It may help your care team track you more closely using scheduled visits and blood tests.
ParisAges 18 years+ - NCT04424979Recruiting
Testing prism glasses for certain types of visual field loss
This study checks whether different prism “glass” settings are feasible and helpful for people with certain types of vision field loss. You would attend testing sessions lasting about 2–4 hours to see how well the prism glasses can be used safely.
Boston, MassachusettsAges 7–80 - NCT04425434Recruiting
Treatment plan study for children with retinoblastoma
This trial looks at care recommendations for children with retinoblastoma (a childhood eye cancer). It may help standardize the best treatment approach for different patterns of tumor spread.
OuagadougouAges Up to 18 years - NCT04439552Recruiting
MRI study during cornea cross-linking for keratoconus
This trial uses an MRI scan (and a close-up eye scan) to study what happens in the cornea during treatment for keratoconus. It may help doctors better understand how treatment works and who benefits most.
Boston, MassachusettsAges 8–35
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.