Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07481487Recruiting
Cataract and vision correction surgery outcomes
This trial looks at results after cataract or vision correction surgery, like lasik or lens implants. It helps doctors improve care.
Bristol, EnglandAges 18 years+ - NCT06775561Recruiting
Study of hidden DNA causes for rare neuromuscular and epilepsy diseases
This study is for people with a neuromuscular disease or epilepsy whose genetic testing hasn't found a clear answer. It uses advanced techniques to look at parts of the DNA that don't code for proteins, to find hidden causes and help guide future treatments.
BolognaAges Any age - NCT06781970Recruiting
Vitamin C for eye cell protection during cataract surgery
This trial tests whether taking vitamin C before and after cataract surgery can help protect the inner layer of the eye. It is for people aged 60 or older with hard, age-related cataracts who are having phacoemulsification surgery.
Jakarta, DKI JakartaAges 60 years+ - NCT06771427Recruiting
Exosomes for Sjogren's and Dry Eye
This study looks at tiny particles called exosomes in tears to find new ways to diagnose or treat Sjogren's syndrome and dry eye disease. It may help people with these conditions by learning more about what causes them.
Taipei, TaiwanAges 20–75 - NCT07480343Enrolling by invitation
Five-year follow-up after CREST glaucoma study
This study follows up with people who finished the CREST study to check how their eyes are doing 5 years later. It looks at the long-term results of a prior glaucoma treatment.
Newport Beach, CaliforniaAges Any age - NCT07472231Recruiting
Game-based therapy for children with lazy eye
This trial tests if a fun, game-based training program can improve vision in children with lazy eye caused by a difference in glasses prescription between the two eyes. It is designed for children ages 4 to 7 who can participate in vision exercises.
Shanghai, Shanghai MunicipalityAges 4–7 - NCT07480720Recruiting
Thyroid autoimmunity and eye changes in Graves disease
This study looks at how inflammation and thyroid autoimmunity in Graves disease may cause changes in the retina at the back of the eye. It uses a special eye scan (OCT) to measure those changes and compares results between people with Graves disease and healthy volunteers.
Elâzığ, ElaziğAges 18 years+ - NCT07476053Recruiting
How light exposure affects migraine and sleep
This study looks at how office lighting and sleep quality affect migraine. You'll track your headaches and light exposure. The goal is to find ways to improve sleep and reduce migraine attacks.
Tempe, ArizonaAges 18 years+ - NCT06659419Recruiting
Cataract surgery registry using Centurion machines
This study collects information from people who had routine cataract surgery with a specific machine (Centurion). It helps doctors learn more about how these surgeries go and improve care.
ParisAges Any age - NCT07468409Recruiting
JASPER Robotic System for Cataract Surgery
This trial is testing a new robotic system called JASPER to help perform cataract surgery. It looks at how well and safely the robot assists during the operation, which may help improve precision and recovery.
Makati City, National Capital RegionAges 55–80 - NCT07462897Recruiting
New lens to slow nearsightedness in children
This trial tests a special eyeglass lens designed to slow down the worsening of nearsightedness (myopia) in children ages 6 to 14. It aims to keep their eyesight from getting worse quickly.
ParisAges 6–14 - NCT07471295RecruitingPhase 4
Study of a toric lens for cataract with astigmatism
This study tests a special lens implant (toric lens) for people having cataract surgery who also have astigmatism. The lens corrects both the cataract and the astigmatism, potentially giving you clearer distance vision without glasses.
Prague, PragueAges 18 years+ - NCT06788418Recruiting
Comparing SMILE, ICL, and Alcon Lasers for Nearsightedness
This study compares three different methods to correct nearsightedness: SMILE laser, ICL implantable lenses, and Wavelight Plus laser. The goal is to find which works best for you.
BeijingAges 18–40 - NCT07465913RecruitingPhase 4
Rocklatan vs Latanoprost after DSLT laser
This study compares two eye drops—Rocklatan and latanoprost—for people with open-angle glaucoma who have already had a laser treatment (DSLT). It tests whether one drop works better than the other at lowering eye pressure after the laser.
Beaumont, TexasAges 18 years+ - NCT07468058Recruiting
Diabetic eye disease study in Da Nang
This study looks at how common diabetic retinopathy is and what factors increase the risk. It may help find better ways to prevent vision loss in people with diabetes.
Da NangAges 18 years+ - NCT07468877Recruiting
Comparing two cataract surgery systems for bilateral cataract removal
This trial compares two machines used during cataract surgery to see which one uses less energy and ultrasound time. If you are healthy and need cataract surgery in both eyes, this study might help determine the best approach.
Los Angeles, CaliforniaAges 18 years+ - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+ - NCT06791226Recruiting
Testing FAPI PET/CT for eye socket tumors
This study tests whether a new type of PET/CT scan (FAPI) can provide better images of tumors in the eye socket than the standard FDG scan. If you have a suspected or newly diagnosed orbital tumor, joining could help doctors see your tumor more clearly.
Beijing, Beijing MunicipalityAges 3–80 - NCT06792422RecruitingPhase 4
Oral semaglutide for open-angle glaucoma
This trial tests if an oral medication called semaglutide can help people with open-angle glaucoma. It aims to see if it can protect the optic nerve and manage eye pressure.
Glostrup MunicipalityAges 45 years+ - NCT07453888RecruitingPhase 3
Nose spray for sudden vision loss from optic nerve damage
This trial tests a nose spray medication (cenegermin) for people who recently lost vision due to a specific type of optic nerve damage (NAION). The goal is to see if it can help restore sight when started within two weeks of vision loss.
Los Angeles, CaliforniaAges 50–80 - NCT07456826Enrolling by invitationPhase 4
Comparing two eye numbing gels for shots
This trial tests a new eye-numbing gel against the standard numbing method to see which works better for patients getting regular anti-VEGF injections in the eye.
Tyler, TexasAges 18 years+ - NCT07460557Recruiting
Link between jaw shape and vision
This study looks at how the shape of your jaw and face might relate to your eyesight. Healthy young adults aged 21 to 25 are needed to see if there is a connection.
ZagrebAges 21–25 - NCT07458516Recruiting
Observing eye disease progression in type 2 diabetes
This study closely follows people with type 2 diabetes who have early signs of diabetic retinopathy (damage to the retina from diabetes) to see how the condition changes over time. It does not test a new treatment but monitors the eye's health closely. It may be a good fit if you have diabetic retinopathy that does not need immediate treatment.
CoimbraAges 35–80 - NCT07461441RecruitingPhase 3
Personalized faricimab for new polypoidal choroidal vasculopathy
This study tests a personalized treatment plan using an investigational drug called faricimab for people who have a specific type of wet age-related macular degeneration known as polypoidal choroidal vasculopathy. The goal is to see if adjusting the time between injections based on your individual needs can safely dry up fluid in the retina and improve vision.
Daegu, NamguAges 50 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.