Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT03648814Recruiting
Bevacizumab eye injections for neovascular glaucoma
This study compares two ways of giving the medicine bevacizumab in the eye: into the front part (intracameral) versus deeper inside (intravitreal). It aims to see which approach better controls neovascular glaucoma and helps vision, especially when surgery (trabeculectomy) is needed.
Hat Yai, Changwat SongkhlaAges 18 years+ - NCT03655912Recruiting
Video games and eye therapy for lazy eye
This study tests whether binocular (two-eye) visual therapy using video games can improve “lazy eye” vision. It’s aimed at people with certain types of lazy eye and who have not had previous amblyopia treatment.
Monterrey, Nuevo LeónAges 4–10 - NCT03680794Recruiting
Testing a blood and eye-fluid marker in retinal disease
This study looks at a specific lab marker (sCD160) in blood and eye fluids to see how it relates to poor blood flow in the retina. You may be asked for samples taken during eye surgery to help doctors understand the disease better.
ReimsAges 18 years+ - NCT03686124RecruitingPhase 1/Phase 2
Tested immune therapy for certain HLA-A2 positive solid tumors
This trial studies an immune-based cancer treatment (IMA203/IMA203CD8) either alone or with nivolumab in people whose solid tumors have come back or will not respond to standard care. It may help by training the immune system to recognize and attack tumor cells that match the trial’s test requirements.
Stanford, CaliforniaAges 18 years+ - NCT03694626Recruiting
Test a light-response study to measure and track light sensitivity
This study aims to objectively measure how your pupils respond to light and how your eye muscles react using recording tests. It may help confirm the cause of light sensitivity (especially after a brain injury) and better track how it responds to care.
Iowa City, IowaAges 18–80 - NCT03708627RecruitingEarly Phase 1
Bimatoprost for eye swelling in Graves’ orbitopathy
This early study tests whether bimatoprost (eye drops) can reduce signs of Graves’ orbitopathy, a condition that can cause bulging eyes. It may help improve eye symptoms for people whose Graves-related eye problems are present.
Seattle, WashingtonAges 18 years+ - NCT03713268Recruiting
Using a scan to guide eye surgery in real time
This trial tests whether a special eye scan (OCT) can help guide eye surgery during the operation. It may improve how surgeons see and target the exact eye structures they need to treat.
Durham, North CarolinaAges 4 weeks+ - NCT03752840Recruiting
Community eye-worker program in Nepal
This trial tests a village-based approach to bring eye care closer to older community members. If you live in the right area and are willing to participate, it may help improve access to eye screening and services.
San Francisco, CaliforniaAges 60 years+ - NCT03760432Recruiting
Cornea strengthening study for keratoconus using collagen cross-linking
This trial studies collagen cross-linking, a procedure meant to strengthen a weakened cornea in people with keratoconus. It may help slow the bulging/weakening of the cornea and improve vision, and the study also uses special imaging to check changes over time.
Portland, OregonAges 18 years+ - NCT03767530Recruiting
Warm or heat devices for eyelid oil gland blockage
This study tests heated devices to see if they improve dry eye caused by blocked meibomian (eyelid oil) glands. It may help if warm compresses and gentle eyelid massage didn’t work for you.
Monterrey, Nuevo LeónAges 18 years+ - NCT03803852Recruiting
Testing different toric lens types during cataract surgery
This study compares different types of artificial lens implants (including toric lenses that correct astigmatism) during cataract surgery. It may help find which lens options work best for your vision and astigmatism correction.
Vienna, State of ViennaAges 45–95 - NCT03809585Recruiting
Study of iris tumors and healthy eyes
This observational study looks at eyes with iris tumors and compares them to eyes without iris problems. The goal is to better understand how iris circulation and related eye measurements differ, which may help future care.
Portland, OregonAges 18 years+ - NCT03812016Recruiting
Feedback device for temporary eyelid droop treatment
This study tests a special device that uses feedback to temporarily manage blepharoptosis, which means a droopy upper eyelid. It may help improve eyelid position without permanent surgery, but you must be able to follow the study steps.
Kaohsiung CityAges 18–85 - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Birmingham, AlabamaAges 18 years+ - NCT03870230Recruiting
Study of eye blood-flow signals in glaucoma and healthy eyes
This study compares eye blood-flow/brain-eye communication signals in people with glaucoma (or high eye pressure) versus people with normal eye tests. It may help researchers understand how glaucoma develops and progresses.
ViennaAges 18 years+ - NCT03872102Recruiting
Brain imaging study to track Parkinson-related disease changes
This study uses brain scans and clinical check-ins to better diagnose and predict how Parkinson-related conditions may progress over time. It may help researchers find markers that explain why symptoms change, and could improve future care.
Dallas, TexasAges Any age - NCT03900221Recruiting
Pregnancy monitoring registry for multiple sclerosis in France
This study follows people who are pregnant and have multiple sclerosis (or related conditions) to better understand what happens during pregnancy. It does not appear to test a new treatment; it mainly collects health and pregnancy information.
AmiensAges Any age - NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT03921931Recruiting
Test retinal responses to light in healthy eyes or eye disease
This is a small pilot study that measures how parts of the retina change before and after light stimulation. It may help researchers understand eye function in people with normal vision or specific eye conditions like glaucoma or dry age-related macular degeneration (AMD).
Vienna, State of ViennaAges 18 years+ - NCT03922542RecruitingPhase 2/Phase 3
Compare faster versus standard corneal strengthening
This trial compares two ways to strengthen the cornea (the clear front surface of your eye) in people with keratoconus or corneal weakening after laser vision surgery. It may help determine whether an accelerated (faster) approach works as well and with acceptable safety.
Indianapolis, IndianaAges 10 years+ - NCT03923101Recruiting
Study for people with keratoconus at a specialty eye clinic
This trial is for people who have keratoconus (a cornea condition that can blur vision). It involves receiving care or evaluation at the Homburg Keratoconus Center, and it may help by improving how keratoconus patients are managed.
Homburg, SaarlandAges Any age - NCT03932786Recruiting
Study of health and wellbeing after retinoblastoma treatment
This study looks at long-term health outcomes—how patients are doing physically and in daily life—after treatment for retinoblastoma. It may help doctors understand what support or follow-up care could be most helpful after treatment.
Chicago, IllinoisAges Any age - NCT03933631RecruitingPhase 3
Pilocarpine eye drops after glaucoma drainage surgery
This trial tests whether pilocarpine eye drops work better after a specific glaucoma surgery called Kahook goniotomy done at the same time as cataract surgery. It may help lower eye pressure and support better glaucoma control after surgery.
The Bronx, New YorkAges 30–100 - NCT03947385RecruitingPhase 1/Phase 2
First drug test for metastatic uveal melanoma with specific gene changes
This Phase 1/2 trial studies IDE196 in adults with metastatic uveal melanoma that has certain gene mutations or fusions. It’s mainly testing safety and correct dosing, and may help shrink tumors in patients matched to the tumor’s genetic changes.
Los Angeles, CaliforniaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.