Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT06749639RecruitingEarly Phase 1
Gene therapy trial for RDH12-related eye disease
This trial tests an injection called PUMCH-E101 for people with vision loss caused by changes in the RDH12 gene. The goal is to see if it is safe and if it can help improve vision.
Beijing, Beijing MunicipalityAges 8–45 - NCT06754358RecruitingPhase 1
Comparing two laser systems for cataract surgery
This study compares two types of femtosecond lasers used during cataract surgery. It is for people of Chinese Han ethnicity who are 40 or older and have age-related cataracts.
Hangzhou, ZhejiangAges 40 years+ - NCT07522242RecruitingPhase 2
Eye Drops to Slow Nearsightedness in Children
This study tests a new eye drop medicine (T10430) to see if it can slow down how fast children's nearsightedness gets worse. The trial will measure whether the drops are safe and effective for kids ages 6–11.
AmmanAges 6–11 - NCT07520175Enrolling by invitation
Bio-Reinforced Canaloplasty for Open-Angle Glaucoma
This study tests a newer surgical procedure called bio-reinforced canaloplasty, which helps fluid drain better from the eye to lower eye pressure in people with open-angle glaucoma. Researchers will follow patients to see how well this procedure works and how safe it is.
Chico, CaliforniaAges Any age - NCT07519902RecruitingPhase 3
Cenegermin Eye Drops for Persistent Corneal Ulcers
This study tests whether cenegermin eye drops help heal stubborn corneal ulcers (open sores on the clear front of the eye) that haven't improved with standard treatments like lubricating drops or contact lenses.
Huntington Beach, CaliforniaAges 18 years+ - NCT06756009Recruiting
Eye scans to check liver disease and transplant outlook
This study uses advanced eye scans to see if your eyes can give clues about your chronic liver disease and how well you might do after a liver transplant. If you have advanced liver disease or cirrhosis, and are maybe waiting for a transplant, you may join.
Guangzhou, GuangdongAges 18 years+ - NCT07520045Recruiting
Eye Injections for Diabetic Vision Loss: Two Treatment Comparison
This study compares two injectable medications (faricimab and biosimilar ranibizumab) used to treat diabetic retinopathy, a serious eye condition that can cause vision loss in people with diabetes. The trial will measure how well each medication works and track specific markers in your eye to understand treatment response.
OsijekAges 18 years+ - NCT07518134Recruiting
Understanding Uveitis in Children Under 18
This study looks at uveitis, a type of eye inflammation, in children. Researchers want to learn more about different types of uveitis and how they affect children, whether the inflammation is new or has been going on for a while.
Boston, MassachusettsAges Up to 17 years - NCT07523139Recruiting
Eye Structure Study in Angle-Closure Glaucoma
This research study uses ultrasound imaging to examine the internal structures of the eye in people with angle-closure glaucoma (a type of increased eye pressure) and compares them to healthy eyes. Understanding these structures may help doctors better diagnose and treat this eye condition.
BeijingAges 30–79 - NCT07517302Recruiting
Dual Blade Surgery for Angle-Closure Glaucoma With Cataracts
This trial tests a new surgical technique called Kahook Dual Blade goniotomy combined with cataract removal in patients with chronic angle-closure glaucoma—a condition where fluid pressure builds up in the eye because drainage channels are blocked. The goal is to lower eye pressure and help preserve vision.
BeijingAges 40 years+ - NCT07509229Enrolling by invitationPhase 1/Phase 2
Algae Extract for Retinitis Pigmentosa
This study tests an extract from a type of algae that is rich in a special form of vitamin A. It may help improve vision for people with retinitis pigmentosa caused by certain gene mutations that affect how the eye processes vitamin A.
Tel LitwinskyAges 18 years+ - NCT07515079RecruitingPhase 3
Testing BAT5906 vs Lucentis for diabetic vision swelling
This study compares two injectable medicines (BAT5906 and Lucentis) to treat diabetic macular edema—swelling in the back of the eye that blurs vision. Both drugs block a protein that causes abnormal blood vessel leakage, and this trial will show which works better.
Beijing, Beijing MunicipalityAges 18–80 - NCT07516132RecruitingPhase 3
Long-term safety study of axitinib implant for wet macular degeneration
This study follows people who completed an earlier 2-year trial of OTX-TKI, a small implant placed in the eye to treat wet age-related macular degeneration (a condition causing vision loss). Researchers want to make sure the treatment remains safe over time.
Bakersfield, CaliforniaAges 50 years+ - NCT07514039Enrolling by invitation
Special Myopia Glasses for Children and Teens
This study tests new glasses with special microscopic patterns designed to slow down myopia (nearsightedness) in children and teenagers. Researchers want to see if wearing these glasses can help prevent myopia from getting worse.
ShanghaiAges 6–14 - NCT07512102Recruiting
Eye Surgery Approach for Nearsightedness With Specific Eye Alignment
This study compares two different computer-guided surgical techniques for correcting nearsightedness using a laser eye procedure called SMILE. The research tests whether adjusting for your eye's natural alignment during surgery affects your vision results.
Guangzhou, GuangdongAges 18–40 - NCT07510620RecruitingPhase 4
Dry eye treatment for contact lens wearers
This trial tests a treatment for dry eye in people who wear contact lenses. It may help if you've tried other dry eye treatments before.
Kingston, PennsylvaniaAges 22 years+ - NCT07512089Recruiting
Blended Vision vs. Monovision LASIK for Reading Age
This study compares two laser eye surgery approaches for people over 40 who need reading glasses. Both methods use LASIK to reduce or eliminate your need for glasses, but they work differently—one eye may be set for distance and one for close-up (monovision), or both eyes may be adjusted for mixed vision (blended vision).
Guangzhou, GuangdongAges 40–55 - NCT07512115Recruiting
Eye Surgery Alignment Study for Nearsightedness
This study tests whether a small adjustment during laser eye surgery for nearsightedness improves your vision outcomes. You'll be randomly assigned to receive either standard surgery or surgery with a minor compensation adjustment, and researchers will compare how well you see afterward.
Guangzhou, GuangdongAges 18–40 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07515521Recruiting
Vision and Imaging Tests for Early and Intermediate AMD
This study tests new ways to measure vision and take detailed eye images in people with age-related macular degeneration (AMD), a common eye condition affecting central vision. The goal is to develop better tools for future AMD treatment trials.
BonnAges 18 years+ - NCT07510087Recruiting
Glaucoma and quality of life study
This study examines how glaucoma affects day-to-day life. It asks people with any type of glaucoma to complete a questionnaire about their quality of life.
Iowa City, IowaAges 18 years+ - NCT06760910Recruiting
tDCS for older teens and adults with lazy eye
This study tests a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) to see if it can help improve vision in older children and young adults with amblyopia (lazy eye).
Tianjin, Tianjin MunicipalityAges 10–30 - NCT07502664Recruiting
A study on vision and navigation in inherited retinal disease
This study is looking at how people with inherited retinal disease that affects peripheral vision see and move around. It will test a new way to measure vision and navigation to see if it can help doctors understand how the disease affects daily life.
Irvine, CaliforniaAges 18 years+ - NCT07502456Recruiting
Clareon TruPlus study for cataract patients with astigmatism
This trial tests a new type of lens (toric IOL) to correct both cataracts and astigmatism in one surgery. It may help you see clearly without glasses if you have cataracts and a mild to moderate astigmatism.
Phoenix, ArizonaAges 22 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.