Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT07378956Recruiting
AI eye screening for diabetes patients
This study uses an artificial intelligence (AI) tool to analyze eye images in people with type 2 diabetes. The goal is to see if the AI can help detect early signs of diabetic eye disease, so you can get the right care sooner.
Incheon, Gyeonggi-doAges 19 years+ - NCT07371468RecruitingPhase 1
Study of an experimental drug for lupus, rheumatoid arthritis, and related conditions
This trial tests a new drug called GSK5926371 for people with certain autoimmune diseases that affect the joints, skin, and other tissues. It aims to see if the drug is safe and how well it works.
Buenos AiresAges 18–70 - NCT04016675Recruiting
Radiation before surgery for cancer of the tear sac
This trial studies giving radiation before surgery for malignant (cancerous) tumors of the tear sac. It may help shrink the tumor and improve how well treatment works when surgery is planned.
ShanghaiAges 18–80 - NCT04903678Recruiting
Chemo into spinal fluid for advanced retinoblastoma spread
This trial studies giving chemotherapy directly into the spinal fluid to treat retinoblastoma that has spread to the central nervous system (brain/spinal cord). It may help by targeting tumor cells that are in the fluid around the brain and spinal cord.
ShanghaiAges Any age - NCT05379855Recruiting
Eye drops for eye alignment and double-vision control in children
This study tests eye drops to improve how a child’s eyes line up and how well they can use both eyes together. It may help children with certain types of outward eye drifting (intermittent exotropia/exophoria).
ShanghaiAges 5–14 - NCT05126147RecruitingPhase 4
Hydroxychloroquine for mild Graves’ eye swelling
This trial studies whether hydroxychloroquine can improve mild Graves’ orbitopathy (swelling and discomfort around the eyes). It’s meant for people with mild symptoms and who haven’t recently used certain eye or immune treatments.
HsinchuAges 18–75 - NCT06112340RecruitingPhase 2/Phase 3
Extension study of linsitinib for thyroid eye disease
This trial tests two doses of an oral medication (linsitinib) for people with active, moderate-to-severe thyroid eye disease who were in a previous study and didn't improve enough or had their bulging come back. It aims to see if continuing treatment can help with eye bulging and other symptoms.
Miami, FloridaAges 18 years+ - NCT06808633Recruiting
Laser treatment for open-angle glaucoma results
This trial tests how well a laser treatment called selective laser trabeculoplasty works in people with open-angle glaucoma. It looks at results over 12 months to see if it helps lower eye pressure.
Madrid, MadridAges 18 years+ - NCT07364708Recruiting
Treating eye membrane detachment after cataract surgery
This trial tests a way to reattach the thin inner layer of the cornea (Descemet's membrane) that can detach after cataract surgery. It may help people who are diagnosed within the first week after surgery.
Minya, None SelectedAges 50 years+ - NCT07363824Recruiting
Tear iron and dry eye severity study
This study looks at how iron levels in tears relate to the severity of dry eye disease. It aims to find a simple way to measure dry eye severity, which could help doctors better understand and treat the condition.
ShanghaiAges 18–70 - NCT07369804Recruiting
Red-light therapy for myopia in adults
This study tests whether a special red-light device can safely slow or stop nearsightedness from getting worse in adults. You'll use the light at home for a few minutes each day, and the team will check your vision over time.
Hong Kong, Hong KongAges 18–50 - NCT07363889Recruiting
Spring syringe removal of silicone oil
This trial uses a special spring-loaded syringe to remove silicone oil from the eye after a previous vitrectomy surgery. It may offer a simpler way to take out the oil for people who don't have certain eye problems.
Sohag, Sohag GovernorateAges 18 years+ - NCT07366944Recruiting
PCOS, eye dryness, and lifestyle changes trial
This trial tests if lifestyle changes can help with eye dryness in women with PCOS and obesity. It looks for improvements in dry eye symptoms.
Giza, DokkiAges 30–40 - NCT07364474Recruiting
Immune response to liver perfusion therapy for eye melanoma
This study tests how well the liver responds to a treatment called percutaneous hepatic perfusion with melphalan (chemotherapy delivered directly to the liver) in people with uveal melanoma that has spread to the liver. The goal is to see how the immune system reacts and if the treatment helps control the disease.
Boston, MassachusettsAges 18 years+ - NCT07362927RecruitingEarly Phase 1
Gene therapy trial for diabetic macular edema
This study tests a new gene therapy called LX111 for diabetic macular edema (DME) that has not improved enough with previous injections. It aims to see if a single treatment can reduce swelling and improve vision.
ShanghaiAges 18 years+ - NCT07364929Recruiting
Glaucoma and its effects on sleep, mood, and thinking
This study looks at how glaucoma affects your body's natural light sensing, which can impact sleep, alertness, mood, and memory. Researchers compare people with glaucoma to healthy volunteers to understand these effects better.
SingaporeAges 45–75 - NCT07369063RecruitingPhase 2
Vitamin D for pediatric Graves' disease
This study tests whether adding vitamin D therapy to the usual Graves' disease treatment (methimazole) can improve thyroid function and lower antibody levels in children. If your child is between 9 and 17 and recently diagnosed, they may be able to participate.
New Hyde Park, New YorkAges 9–17 - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07367282RecruitingPhase 4
Faricimab for newly diagnosed wet age-related macular degeneration
This study tests if faricimab, an injectable eye medication, can improve vision in people with a newly diagnosed form of wet age-related macular degeneration (AMD). It is for patients who have not yet received treatment for this condition.
SeongnamAges 50 years+ - NCT07362043Recruiting
Laser tool for cataract surgery
This study tests a handheld laser device used during cataract surgery to create a precise opening in the lens capsule. It may help surgeons improve accuracy and safety during the procedure.
Saint-HerblainAges 18 years+ - NCT07370584RecruitingPhase 1
Safety study of IVMED-85 eye drops in healthy adults
This phase 1 trial tests the safety of an investigational eye drop called IVMED-85 in healthy adults aged 18-49. Participants will receive the eye drops and be monitored for any side effects over 6 weeks.
Memphis, TennesseeAges 18–49 - NCT02706704RecruitingPhase 2
Adalimumab eye injections vs under-skin shots for uveitis
This trial compares two forms of the same medicine (adalimumab) to treat non-infectious uveitis, an inflammation inside the eye. It aims to see which delivery method works better to control active inflammation and protect vision.
BeirutAges 18 years+ - NCT05540262Recruiting
Edaravone for new anti-AQP4 optic neuritis
This trial tests edaravone, a medicine intended to reduce damage from optic neuritis, in adults whose condition is confirmed by a positive blood test for anti-AQP4 antibodies. It may help people who are in the first month after their first episode to preserve or improve vision.
NanningAges 18–70 - NCT07354945Recruiting
Study of myopia control lenses in children
This study tests how well children adapt to special myopia control lenses. It aims to see if these lenses are comfortable and easy to wear for kids with nearsightedness.
Shanghai, Shanghai MunicipalityAges 6–12
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
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- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.