Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05366933RecruitingPhase 1
B-Complex vitamins to protect astronauts during long space missions
This early study tests whether a B-vitamin supplement (called B-Complex) can act as a helpful countermeasure during long stays on the International Space Station. It is only for astronauts assigned to specific 6–12 month missions.
Houston, TexasAges 20–100 - NCT05370287Recruiting
Adaptive-eye imaging for adults with primary open-angle glaucoma
This study uses a special “adaptive optics” camera to take very detailed pictures of the retina (the light-sensing layer at the back of the eye). It is meant for adults with primary open-angle glaucoma to improve how well the images can be captured and studied.
Silver Spring, MarylandAges 21 years+ - NCT05371977Recruiting
Deep sclerectomy or trabeculectomy for normal tension glaucoma
This trial compares two types of glaucoma surgery to lower pressure and protect vision in people with normal tension glaucoma. If your glaucoma is not well controlled on drops, you may be considered to help find which surgery works better and more safely.
HelsinkiAges 55–100 - NCT05372861Recruiting
Eye test using nanopore sequencing for endophthalmitis
This trial studies endophthalmitis, an infection inside the eye, using a genetic test to better understand what’s causing it. It may help doctors learn more about the infection and guide treatment decisions in the future.
Graz, StyriaAges 18–99 - NCT05379855Recruiting
Eye drops for eye alignment and double-vision control in children
This study tests eye drops to improve how a child’s eyes line up and how well they can use both eyes together. It may help children with certain types of outward eye drifting (intermittent exotropia/exophoria).
ShanghaiAges 5–14 - NCT05390801Recruiting
Congenital aniridia patient survey for adults and families
This trial collects information from people born with congenital aniridia (a rare eye condition) using a questionnaire or survey. It may help researchers better understand patient needs and experiences to improve future care.
ParisAges Any age - NCT05394987Recruiting
Testing new glasses and vision function in amblyopia adults
This study looks at how changing your glasses prescription affects vision and visual function in adults with amblyopia (often called “lazy eye”). It may help researchers understand which optical correction best supports clearer, more balanced vision.
Waterloo, OntarioAges 18–39 - NCT05397873Recruiting
Biofeedback training to improve vision in hemianopia
This trial tests whether guided “biofeedback” training can help people with hemianopia (a vision field loss) improve how they use their remaining vision. You may be asked to complete vision testing and practice exercises while receiving feedback based on your responses.
Toronto, OntarioAges 18–90 - NCT05401357RecruitingPhase 3
Test eye drops for glaucoma or high eye pressure in both eyes
This Phase 3 study compares two versions of the same glaucoma eye-drop medicine (bimatoprost 0.01%) to see how similarly they work and their effect on eye pressure. It may help people with chronic open-angle glaucoma or ocular hypertension who need treatment in both eyes.
Newport Beach, CaliforniaAges 18 years+ - NCT05400590Recruiting
Test blood-based eye drops to help cornea healing
This study compares two types of blood-derived treatments (a growth-factor enriched plasma product versus your own serum) to see which helps corneal cells heal better in people with aniridia. It may be helpful if you need improved cornea healing, but you must meet blood-safety and eye-sample requirements.
ParisAges 18 years+ - NCT05405868RecruitingPhase 3
Nicotinamide for early to moderate open-angle glaucoma
This trial tests whether nicotinamide (a form of vitamin B3) can slow vision changes from open-angle glaucoma. It compares nicotinamide versus a placebo (inactive pill) in adults with early to moderate disease.
Belfast, Northern IrelandAges 18 years+ - NCT05414994Recruiting
Study eye bacteria in healthy and eye disease
This study compares the tiny living organisms (“ocular microbiome,” meaning eye-surface bacteria) in different eye conditions. It may help researchers understand how these eye bacteria relate to diseases and why some people develop problems with vision.
Nashville, TennesseeAges 18 years+ - NCT05426044RecruitingPhase 2
Metformin to protect the optic nerve in glaucoma
This study tests whether metformin can slow damage to the optic nerve in people with glaucoma. It uses eye scans and vision tests to look for changes over time, aiming to help preserve sight.
Wong Chuk HangAges 18 years+ - NCT05432336Recruiting
Testing better lab diagnosis for serious eye infections
This study looks at how doctors collect and test eye infection samples to get more accurate results, especially in serious cases like corneal abscess or deep eye infection. If you have signs of a complex eye infection and a sample is needed, this trial may help improve the way diagnosis is done for patients like you.
Paris, IDFAges 18 years+ - NCT05436665Recruiting
Cornea transplant surgery for damaged corneal lining in adults
This study looks at a specific type of cornea transplant (called endothelial lamellar transplant) for people with Fuchs disease or other causes of corneal swelling that affect vision. It aims to see whether this surgical approach improves outcomes and quality of life after surgery.
Edegem, AntwerpAges 18 years+ - NCT05438732Recruiting
Test of an implanted eye device plus vision training for AMD
This study tests a device that is surgically implanted in the eye of people with late-stage age-related macular degeneration (AMD). It also uses vision training with a telescope-like tool to see if the treatment can improve day-to-day vision.
Loma Linda, CaliforniaAges 65 years+ - NCT05439161Recruiting
XEN gel stent compared with trabeculectomy for open-angle glaucoma
This trial compares two glaucoma operations to see which works better at lowering eye pressure and keeping the eye stable. It’s for adults with open-angle glaucoma who are eligible for either surgery and can attend follow-up visits.
SalzburgAges 18 years+ - NCT05439200Recruiting
Video-based treatment for lazy eye in young children
This trial tests whether a video treatment can improve “lazy eye” (amblyopia) in children ages 3–7. It may help if your child’s vision difference is present despite glasses worn consistently, and you’re able to skip the usual patching during the study.
Dallas, TexasAges 3–7 - NCT05440448Recruiting
Patch-free therapy for lazy eye in children
This study tests a patch-free treatment approach for “lazy eye” (amblyopia) in children. It may help some kids improve vision without using traditional eye patches, but it requires a willingness to skip standard patching during the study.
Dallas, TexasAges 3–12 - NCT05445063RecruitingPhase 1
iPSC eye-cell transplant for late dry macular degeneration
This Phase 1 study tests an experimental transplant made from your own cells to try to improve vision in people with advanced “late dry” age-related macular degeneration (AMD). It focuses first on safety, and may help some participants with limited central vision.
Beijing, Beijing MunicipalityAges 50–75 - NCT05454124Recruiting
Study of brain-eye learning changes in macular degeneration
This study looks at how the eye’s “central vision” area and connected brain learning/adjustment work in people with advanced macular degeneration. You may be asked to do vision testing using special eye-scanning equipment and follow study procedures that could help researchers better understand the disease.
Birmingham, AlabamaAges 18–89 - NCT05458323Recruiting
Vision testing and glasses change to improve thinking
This study checks whether better distance and near vision (through eye exams and correct glasses) can improve thinking and memory. You may be randomly assigned to receive eye care, and your ability to see and think will be measured.
Hyderabad, TelanganaAges 60 years+ - NCT05461820RecruitingPhase 4
Testing treatment options for Graves’ disease and its relapse
This study compares different treatment plans to see how well they control Graves’ disease and whether it comes back. It may help by identifying which approach works best to prevent relapse.
NanjingAges 18–65 - NCT05465252Recruiting
Omega-3 supplement to slow early dry macular degeneration
This trial studies whether taking omega-3 fatty acids can slow the worsening of dry age-related macular degeneration (AMD) in people with early or intermediate disease. It may help by testing if omega-3 changes how the retina changes over time.
ShanghaiAges 50–85
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.