Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT05472844Recruiting
Study of cataracts in children under 18
This is a research study that follows children with cataracts to learn more about the condition. If your child is under 18 and has a cataract in one or both eyes, this study may be able to include them.
Guangzhou, GuangdongAges Up to 18 years - NCT05474729RecruitingPhase 1/Phase 2
Minocycline for chronic autoimmune eye inflammation
This trial tests whether minocycline, an antibiotic that can also reduce inflammation, helps improve chronic autoimmune uveitis and protect vision. It may help by lowering ongoing immune irritation that damages the eye.
Guangzhou, GuangdongAges 18–70 - NCT05486468RecruitingPhase 3
Two YUTIQ injections versus sham for chronic eye inflammation
This study tests whether receiving two YUTIQ injections works better than a sham (fake) treatment for long-lasting inflammation inside the back part of the eye. It is meant to reduce ongoing “posterior segment” inflammation and improve comfort and eye health when prior steroid treatments have helped but the inflammation keeps coming back.
Plano, TexasAges 18 years+ - NCT05486546Recruiting
Compare two LASIK mapping methods for myopia and astigmatism
This trial compares two ways of mapping your eye to guide LASIK surgery for people with nearsightedness and mild astigmatism. It looks at how well vision (especially best-corrected vision) does after surgery one month later.
Bozeman, MontanaAges 21–38 - NCT05487989Recruiting
Visual pathway study for recent optic neuritis
This study looks at how the eye-to-brain visual pathways work in people who have had optic neuritis symptoms for less than 4 weeks. It may help researchers better understand neuro-inflammatory (nerve inflammation) disorders and improve future care.
LilleAges 18–65 - NCT05500469Recruiting
Test which chamber position protects corneal clarity after glaucoma surgery
This trial studies whether placing a glaucoma drainage device tube in the front part versus the back part of the eye better preserves the cornea’s inner cell layer. You might benefit by using a tube placement that could help keep the cornea clearer for longer after surgery.
RotterdamAges 18–100 - NCT05502900RecruitingPhase 3
Melatonin after eye melanoma to lower spread risk
This Phase 3 study tests whether taking melatonin after treatment for uveal melanoma can reduce the chance that the cancer returns or spreads to other parts of the body. It is aimed at people with higher-risk eye melanoma features.
Stockholm, Stockholm CountyAges 18 years+ - NCT05504291RecruitingPhase 2
Treatment delivered inside the eye for retinoblastoma
This Phase 2 study tests a way to deliver cancer treatment directly inside the eye to treat retinoblastoma. It may help shrink the tumor while limiting treatment to the eye when possible.
Birmingham, AlabamaAges Up to 18 years - NCT05504694RecruitingPhase 1/Phase 2
Ofatumumab for AQP4-positive NMOSD with recent relapses
This trial studies ofatumumab to reduce disease activity in adults with AQP4-IgG positive NMOSD who have had recent relapses. It may help lower the chance of new attacks and help prevent worsening disability over time.
Xi'an, ShaanxiAges 18 years+ - NCT05516004RecruitingPhase 2
Cornea strengthening treatment study for thinning corneas
This Phase 2 study tests whether a procedure called PXL‑Platinum 330 can safely and effectively strengthen corneas that are thinning (such as keratoconus or related conditions). It aims to see if the treatment can help stabilize or improve the cornea’s shape while keeping side effects low.
Boca Raton, FloridaAges 18 years+ - NCT05522972Recruiting
Tests video-game and training therapy for amblyopia
This trial studies whether perceptual learning and video-game style training can improve vision in people with amblyopia (lazy eye). You may be included if you have normal vision or amblyopia, and your eye exam does not show other eye problems that could affect results.
Fort Lauderdale, FloridaAges Any age - NCT05523622Recruiting
Testing a new eye pressure measuring device
This study compares a new device (TonoVera) against other common tools used to measure eye pressure. It may help show whether the new device gives accurate readings and is practical for routine eye exams.
Buffalo, New YorkAges Any age - NCT05540262Recruiting
Edaravone for new anti-AQP4 optic neuritis
This trial tests edaravone, a medicine intended to reduce damage from optic neuritis, in adults whose condition is confirmed by a positive blood test for anti-AQP4 antibodies. It may help people who are in the first month after their first episode to preserve or improve vision.
NanningAges 18–70 - NCT05549258RecruitingPhase 2
Inebilizumab for children with NMOSD who had recent relapses
This trial studies whether inebilizumab can reduce illness activity in children with neuromyelitis optica spectrum disorder (NMOSD), a condition that can cause attacks affecting the eyes and spinal cord. It focuses on kids who have had recent relapses, meaning symptoms came back or worsened.
La Jolla, CaliforniaAges 2–17 - NCT05549713Recruiting
Upper eyelid surgery to improve early vision quality
This study looks at whether upper blepharoplasty (surgery to remove excess upper eyelid skin) improves how clearly you see soon after surgery. It’s mainly for people whose extra upper eyelid skin blocks part of their vision and causes eye opening trouble and headaches.
OsijekAges 45–90 - NCT05558059Recruiting
Scan blood vessels in preemie babies’ eyes with special imaging
This study uses pictures to map the tiny blood vessels in an infant’s retina (the back of the eye). It may help researchers better understand how eye blood vessel growth happens in premature babies who need screening for ROP (retinopathy of prematurity).
Durham, North CarolinaAges Up to 2 months - NCT05561127RecruitingPhase 3
Paclitaxel balloon to treat stubborn non-cancer bowel narrowing
This trial studies a medicine-coated balloon (paclitaxel) placed during endoscopy to keep a non-cancer bowel narrowing (stricture) open longer. It may help reduce repeat procedures if standard balloon dilation hasn’t worked well enough.
Scottsdale, ArizonaAges 22 years+ - NCT05561478Recruiting
Toric versus non-toric cataract lens for clearer vision
This study compares vision outcomes after cataract surgery using two types of intraocular lenses: a toric lens (for astigmatism) versus a standard lens. It aims to see which lens helps people get clearer vision after surgery.
PerpignanAges 50 years+ - NCT05563623Recruiting
Study of people at risk for angle-closure progression
This study follows people who have eye anatomy that suggests a higher risk of angle closure, but who do not currently have high eye pressure or glaucoma damage. It aims to understand how often and how fast this risk can progress, which may help guide earlier monitoring or prevention.
Beijing, BeeijingAges 40–75 - NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+ - NCT05566769Recruiting
Test a phone tool for self-checks in NMOSD
This study tests a digital (phone) tool that helps people with NMOSD do unsupervised self-assessments between clinic visits. It looks at how well the tool works and whether it is safe and understandable for patients.
Los Angeles, CaliforniaAges 18 years+ - NCT05570591Recruiting
Laser treatment for long-lasting central serous eye fluid
This trial tests a low-energy “subthreshold” laser to treat long-lasting fluid under the retina from central serous chorioretinopathy (CSCR). It may help dry up the fluid and improve vision, compared with a sham (placebo) treatment.
East Melbourne, VictoriaAges 18–70 - NCT05573802RecruitingPhase 1/Phase 2
Belantamab and other medicines for new multiple myeloma
This early-phase study tests how safe and effective belantamab mafodotin is when combined with lenalidomide and dexamethasone, plus a medicine called nirogacestat, in people with newly diagnosed multiple myeloma who cannot have stem cell transplant. It may help shrink the cancer and improve outcomes, while doctors track side effects.
AthensAges 18 years+ - NCT05587205RecruitingPhase 1
Tested eye drops for safety in cataract patients with low cornea cells
This Phase 1 study tests how safe and tolerable an investigational treatment (EO2002) is in adults having cataract surgery. It also looks at whether the treatment can be given without causing harmful effects in people with reduced cornea cell counts.
Mexico City, Mexico CityAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.