Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06631339Recruiting
Light therapy to prevent and control nearsightedness in kids
This study tests if optimizing daily light exposure can prevent or slow down nearsightedness (myopia) in children. It involves wearing a light-tracking device and spending time in specially lit classrooms.
SingaporeAges 7–10 - NCT06635148RecruitingPhase 2
Long-term study for geographic atrophy treatment
This study is for people who already took part in a previous trial for geographic atrophy (a late stage of dry age-related macular degeneration) and received the study drug or a sham. It looks at the long-term safety of the treatment over time.
Tucson, ArizonaAges 60 years+ - NCT06638424Recruiting
Cataract surgery effects on eyes in diabetic patients
This study looks at how cataract surgery affects the surface of the eye in people with diabetes. Researchers want to see if the surgery causes changes, so they can better understand and care for diabetic patients.
StrasbourgAges 18 years+ - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT06643338Recruiting
Testing AI to spot eye nerve conditions in the ER
This trial is testing a new computer system that uses photographs of the back of your eye (color fundus photos) to help doctors quickly identify certain nerve or vision problems in the emergency room. If you come to the specific hospital and meet the basic requirements, this study will take pictures of your eyes to see if the AI can spot conditions more accurately.
ParisAges 18 years+ - NCT06643884RecruitingPhase 2
Study of eye injection for cancer that spread to the choroid
This trial tests a new way to deliver treatment directly into the eye (through a thin space near the choroid) for people whose cancer has spread to the eye. It aims to see if this targeted approach can safely shrink the eye tumors.
Palo Alto, CaliforniaAges 18 years+ - NCT06645626Recruiting
Health service use and quality of life in atypical Parkinson's
This study looks at how people with certain rare brain conditions (like progressive supranuclear palsy, corticobasal syndrome, or multiple system atrophy) use healthcare services and how their quality of life is affected. It may help doctors better support patients and their carers.
Southampton, HampshireAges 18 years+ - NCT06647641Recruiting
Genetics study for PSP, CBS, MSA, and related conditions
This study looks at genetic factors in people with PSP, CBS, MSA, or similar brain conditions, and also in their family members. It involves genetic testing to learn more about these diseases and may help find new treatments.
Boston, MassachusettsAges 35 years+ - NCT06652321Recruiting
New laser method for corneal transplant in Fuchs' dystrophy
This trial tests a new way to perform a corneal transplant (DSAEK) using a laser to prepare the donor tissue. It may help people with Fuchs' dystrophy or certain types of corneal swelling, but not those with glaucoma, scarring, or other eye diseases.
GizaAges Any age - NCT06655441RecruitingPhase 4
Trehalose eye drops for dry eye disease
This study tests if a special sugar-based eye drop called trehalose can improve the protective layer of the eye in people with moderate to severe dry eye. It might help strengthen the cornea and reduce discomfort.
Fullerton, CaliforniaAges 18 years+ - NCT06658002RecruitingPhase 3
Testing stronger eye drops for fungal eye infections
This trial tests if adding cyclosporine A to the standard natamycin eye drops can better treat fungal eye infections. It may help people with moderate vision loss from a fungal corneal infection.
San Francisco, CaliforniaAges 18 years+ - NCT06658119Recruiting
Wide-focus lens for cataract surgery: a clinical trial
This study tests a new type of lens implant that gives you a wider range of clear vision after cataract surgery. It uses a special laser to help remove the cataract, and the lens may help you see better at near, far, and in between without glasses.
Hangzhou, ZhejiangAges 40–80 - NCT06659419Recruiting
Cataract surgery registry using Centurion machines
This study collects information from people who had routine cataract surgery with a specific machine (Centurion). It helps doctors learn more about how these surgeries go and improve care.
ParisAges Any age - NCT06662448Recruiting
Light stimulation for nerve damage in the eye
This study tests if a gentle electrical current, like a light flicker, can help people with optic neuropathy (damage to the nerve connecting the eye to the brain). You would attend 30 sessions over 8 weeks. It might improve your vision if you still have some sight left.
New York, New YorkAges 18 years+ - NCT06662994RecruitingPhase 4
High dose aflibercept for diabetic macular edema after vitrectomy
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
Fullerton, CaliforniaAges 21 years+ - NCT06669728Recruiting
ICL eye surgery prediction study using eye images
This study tests if a computer model can look at images of your eye to help predict whether ICL surgery (a type of vision correction) will work well. It may help find the best lens size for people with nearsightedness.
Nanchang, JiangxiAges 18–45 - NCT06672913Recruiting
Skin-to-skin care study for premature babies
This study looks at how holding your baby skin-to-skin affects their health and development, for babies born at 32 weeks or earlier.
AnkaraAges 1 day+ - NCT06679634RecruitingPhase 2
Topotecan eye patch for retinoblastoma
This trial tests a new way to deliver the chemotherapy drug topotecan directly to the eye (via a small patch placed on the eye surface) for children with retinoblastoma that either needs eye removal or has come back after standard treatment. It aims to see if this approach can help save the eye and vision.
New York, New YorkAges Up to 8 years - NCT06680037RecruitingPhase 1
Azer-cel for autoimmune disorders like MS, NMOSD, MG, and CIDP
This trial tests an investigational cell therapy called Azer-cel in people with certain autoimmune diseases that affect the nerves or muscles. It aims to see if the treatment is safe and can help reduce symptoms by targeting the immune system.
La Jolla, CaliforniaAges 18 years+ - NCT06681688RecruitingPhase 1/Phase 2
Comparing two approaches to prevent cataract surgery complications
This study compares two ways to prevent complications after cataract surgery. One group gets a special combination of eye drops and a steroid injection before surgery, and the other group gets standard care. The goal is to see which approach leads to fewer problems after surgery.
Venice, FloridaAges 18 years+ - NCT06682819Recruiting
Looking at eye nerve layers in NOHL gene carriers
This study uses a special eye scan (OCT) to look at the layer of nerve fibers in the retina of people who carry (or don't carry) a specific gene change linked to Leber Hereditary Optic Neuropathy (NOHL). The goal is to find early warning signs in the blood that might show who is at risk of losing vision.
Paris, ParisAges 18–60 - NCT06682962Recruiting
Electrical stimulation for vision loss from glaucoma
This trial tests if a gentle electrical stimulation on the eye can slow or improve vision loss in people with open-angle glaucoma. It uses a device you can use at home after training.
MainzAges 40 years+ - NCT06683651RecruitingPhase 3
Study of a treatment for droopy eyelid in Chinese patients
This study tests a new treatment for Chinese patients whose droopy upper eyelid (acquired blepharoptosis) seriously affects their vision. It may help if your eyelid droops low enough to block part of your sight and you haven't had previous corrective surgery or certain eye conditions.
Hefei, AnhuiAges 18–75 - NCT06685211Recruiting
Electrical stimulation for vision in glaucoma
This trial tests whether gentle electrical stimulation can help improve vision in people with moderate vision loss from glaucoma. It might offer a new way to strengthen remaining vision.
Palo Alto, CaliforniaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.