Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06686472RecruitingPhase 2
Testing TL-925 eye drops for allergic conjunctivitis
This trial tests an investigational eye drop called TL-925 to see if it can treat allergic conjunctivitis (eye allergies). If you have a history of eye allergies and a positive allergy skin test, you may be able to join.
Memphis, TennesseeAges 18 years+ - NCT06687356Recruiting
Using OCT during lens surgery for better results
This study uses a special imaging technique called optical coherence tomography (OCT) during lens surgery to help doctors see inside your eye more clearly. It may be a good option if you need surgery for a cataract or a lens that is out of place.
Hangzhou, ZhejiangAges 18 years+ - NCT06691555Recruiting
Long-term safety of a silicone tube eye implant
This study follows up with people who have previously received a special silicone tube implant in their eye to see how they are doing over time. It aims to check the long-term safety and how well the implant is working.
TbilisiAges 40–90 - NCT06694051Recruiting
Light treatment to mark astigmatism axis
This trial uses a special laser treatment to mark the exact axis of astigmatism for better correction. It might help patients with astigmatism get more precise treatment.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06694103Recruiting
Two ways to reduce pain during a baby's eye exam
This study tests two drug-free methods to help reduce pain when premature babies get a special eye exam for retinopathy of prematurity. It may help your baby feel more comfortable during the procedure.
Izmir, MenemenAges 6 months–8 months - NCT06694272Recruiting
Visual function tests for early age-related macular degeneration
This study looks at how well the eyes function in people with early or intermediate age-related macular degeneration (AMD). It uses imaging and vision tests to help doctors better understand the condition.
ParisAges 18 years+ - NCT06696625Recruiting
Nerve stimulation for dry eye relief
This trial tests if mild electrical pulses on the ear can reduce dry eye symptoms. If you have had dry eye for at least 6 months and meet certain eye test results, this non-drug treatment might help.
Beijing, Beijing MunicipalityAges 18–65 - NCT06697535RecruitingPhase 2
Study of JYP0061 for acute NMOSD attacks
This trial tests a new medication called JYP0061 for people with NMOSD who are currently experiencing a sudden worsening of symptoms (acute attack). It aims to see if the drug can help control the attack and improve outcomes.
Changsha, HunanAges 18–65 - NCT07512089Recruiting
Blended Vision vs. Monovision LASIK for Reading Age
This study compares two laser eye surgery approaches for people over 40 who need reading glasses. Both methods use LASIK to reduce or eliminate your need for glasses, but they work differently—one eye may be set for distance and one for close-up (monovision), or both eyes may be adjusted for mixed vision (blended vision).
Guangzhou, GuangdongAges 40–55 - NCT07512102Recruiting
Eye Surgery Approach for Nearsightedness With Specific Eye Alignment
This study compares two different computer-guided surgical techniques for correcting nearsightedness using a laser eye procedure called SMILE. The research tests whether adjusting for your eye's natural alignment during surgery affects your vision results.
Guangzhou, GuangdongAges 18–40 - NCT04439708Recruiting
Biomarkers for abnormal eye blood vessels
This study is looking for biomarkers (clues in your body) related to abnormal blood vessels in the eye. It may help researchers understand and treat conditions like macular degeneration.
ParisAges 18–90 - NCT07512115Recruiting
Eye Surgery Alignment Study for Nearsightedness
This study tests whether a small adjustment during laser eye surgery for nearsightedness improves your vision outcomes. You'll be randomly assigned to receive either standard surgery or surgery with a minor compensation adjustment, and researchers will compare how well you see afterward.
Guangzhou, GuangdongAges 18–40 - NCT07354477RecruitingPhase 2
New eye drop for glaucoma and diabetic retinopathy
This trial tests a new eye drop (QLS-111) to see if it improves blood flow in the back of the eye. It may help people with mild to moderate glaucoma or stable diabetic retinopathy by reducing pressure inside the eye and nourishing the optic nerve.
Palo Alto, CaliforniaAges 18 years+ - NCT06374264Enrolling by invitation
Music-based walking therapy for NMOSD
This trial tests a music-based walking therapy (called MR-C-014) to see if it is safe and well-tolerated for people with NMOSD who have trouble walking. It may help improve your walking pattern and strength.
Atlanta, GeorgiaAges 18–70 - NCT07587515RecruitingPhase 1/Phase 2
New Eye Drop Treatment for Wet Age-Related Macular Degeneration
This study tests a new experimental eye drop (EYC-0305) for wet AMD, a common cause of vision loss in older adults. The goal is to see if it can slow or prevent further damage to central vision.
Beverly Hills, CaliforniaAges 50 years+ - NCT07100990RecruitingPhase 3
Early plasma exchange for optic neuritis or myelitis
This trial tests if getting plasma exchange early, along with high-dose steroids, helps people with severe optic neuritis or transverse myelitis recover better than waiting to see if steroids alone work. It aims to find out if faster treatment can prevent lasting vision loss or disability.
Scottsdale, ArizonaAges 18 years+ - NCT06789445RecruitingPhase 1/Phase 2
Cell therapy for inherited retinal disease (CLARICO)
This study tests a new cell therapy (OpCT-001) for adults with inherited retinal diseases that affect the light-sensing cells. It aims to see if the treatment is safe and possibly helps improve vision.
Los Angeles, CaliforniaAges 18 years+ - NCT06984627RecruitingPhase 2
Study of Rilzabrutinib for Adults with Graves' Disease
This study tests an experimental pill called rilzabrutinib for people with Graves' disease, a condition where the immune system attacks the thyroid. It aims to see if the drug can help control the overactive thyroid and any related eye problems.
Calgary, AlbertaAges 18–75 - NCT06708156RecruitingPhase 3
Low-dose atropine drops to slow childhood nearsightedness
This trial tests two low-dose atropine eye drops (0.01% and 0.02%) to see if they can safely slow down the worsening of nearsightedness (myopia) in children. Your child would receive either one of these drops or a placebo (an inactive drop) once daily for up to 2 years.
Hefei, AnhuiAges 6–12 - NCT06709339RecruitingPhase 4
Study of faricimab for Caucasian patients with polypoidal choroidal vasculopathy
This trial tests a drug called faricimab for a type of wet age-related macular degeneration called polypoidal choroidal vasculopathy (PCV). It aims to see if the drug is safe, works well, and how long the effects last in patients who have not been treated before.
MilanAges 50–90 - NCT06712758Recruiting
Cataract surgery with new technique for glaucoma patients
This trial tests a newer, gentler cataract surgery method in people who have both glaucoma and cataracts. It aims to lower eye pressure safely during the procedure.
GeelAges Any age - NCT06712849Recruiting
Brain stimulation for adult lazy eye
This trial tests a gentle, noninvasive brain stimulation technique (called TMS) to see if it can improve vision in adults with lazy eye. It is a noninvasive approach that does not involve surgery or drugs.
Downers Grove, IllinoisAges 18–55 - NCT06713720Recruiting
Arm Cuff Therapy for Early Diabetic Eye Disease
This study tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to one arm using a special cuff) can help slow down early-stage diabetic eye disease in people with type 2 diabetes. You join the study to potentially prevent your retinopathy from getting worse.
Beijing, Beijing MunicipalityAges 40–80 - NCT06717048Recruiting
Finding the best red light therapy for myopia in children
This study tests whether a special red light therapy can help slow down the progression of nearsightedness in children. It compares different amounts of light and how often it is used to find the best way to keep myopia from getting worse.
Shanghai, Shanghai MunicipalityAges 8–10
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.