Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT07073937Enrolling by invitation
Three-year results of combined microstent and canaloplasty surgery
This trial is checking how well a combined eye surgery (Hydrus microstent plus canaloplasty plus cataract surgery) works over 3 years. It looks at long-term safety and effect on eye pressure. It's for people with open-angle glaucoma who already had that specific combination of procedures.
Salt Lake City, UtahAges 18 years+ - NCT07073521Recruiting
Cognitive therapy for adjusting to vision loss
This study tests new ways to help people adjust to vision loss using thinking and coping strategies. If you are an adult with vision loss and willing to share feedback, this may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT06984549Recruiting
Dry eye detection via smartphone camera
This study tests if a smartphone can take clear pictures and videos of your eyes to help doctors check for dry eye disease. It may be a simpler way to evaluate dryness from home.
Wenzhou, ZhejiangAges 18 years+ - NCT03870230Recruiting
Study of eye blood-flow signals in glaucoma and healthy eyes
This study compares eye blood-flow/brain-eye communication signals in people with glaucoma (or high eye pressure) versus people with normal eye tests. It may help researchers understand how glaucoma develops and progresses.
ViennaAges 18 years+ - NCT03423758Recruiting
Genetic study of eye diseases: PXF, angle-closure and open glaucoma
This study looks at blood or DNA-related factors that may explain why certain glaucoma and related eye conditions happen. It may help researchers understand risk and causes across different glaucoma types.
ViennaAges 21–105 - NCT03552562Recruiting
Eye blood-flow study in adults with type 2 diabetes
This study measures blood flow and oxygen use in the retina (the light-sensing layer at the back of your eye) in adults with type 2 diabetes and in healthy adults. It may help researchers better understand how diabetes affects the eye.
ViennaAges 18–99 - NCT02585414Recruiting
Eye scans to study dry eye in adults
This study uses a special eye scan (OCT) to measure the tear film in healthy adults and in people with dry eye. It may help researchers understand what’s different in dry eye and how well the scan reflects dry eye symptoms.
ViennaAges 18 years+ - NCT03401879Recruiting
Study eye blood-flow changes in multiple sclerosis
This study measures how blood flow in the eye changes in people with relapsing-remitting multiple sclerosis (RRMS) who previously had optic neuritis. The goal is to understand eye/brain blood-flow signals and how they may relate to MS.
Vienna, AustriaAges 18 years+ - NCT07063719Recruiting
Finding cell markers for rare eye diseases in adults
This study looks for biological markers in the blood or eye samples of people with rare eye diseases compared to healthy volunteers. It aims to better understand and diagnose these conditions.
ParisAges 18 years+ - NCT07059754Recruiting
Cooling treatment for chronic eye surface pain
This trial tests a cooling treatment (EyeCool) for people with long-term pain on the eye's surface. It looks at how the treatment affects the eye's surface structure and inflammation after standard care hasn't worked well enough.
Melbourne, VictoriaAges 22–90 - NCT07063251RecruitingEarly Phase 1
Gene therapy safety study for Stargardt disease in teens
This study tests a new gene therapy called HG005 for Stargardt disease in young people aged 6 to 17. It aims to see if the treatment is safe and tolerable, and how well it works.
ShanghaiAges 6–17 - NCT07062523RecruitingPhase 1/Phase 2
FAPI PET scan for Sjögren's syndrome inflammation
This study uses a special PET scan (FAPI PET) to look at inflammation in people with Sjögren's syndrome. It helps doctors understand how active the disease is. You may join if you have Sjögren's syndrome or a solid tumor that needs this scan, and you are not on certain medications.
BeijingAges 18–80 - NCT07063030RecruitingEarly Phase 1
Gene therapy trial for AIPL1-related eye disease
This trial tests a gene therapy called LX107 for people with vision loss caused by changes in the AIPL1 gene. It aims to see if the treatment is safe and can improve vision.
ShanghaiAges 4 years+ - NCT07063875RecruitingPhase 1/Phase 2
Adding IL-2 to tebentafusp for advanced eye cancer
This trial tests if adding another drug called IL-2 to tebentafusp can help stop cancer from growing in people with advanced melanoma that started in the eye (uveal melanoma). It is for those whose cancer got worse while on tebentafusp alone.
Sydney, New South WalesAges 18 years+ - NCT07059507Recruiting
Thyroid cancer in Graves' disease patients having thyroid surgery
This study looks at how often thyroid cancer is found by accident in people with Graves' disease who have their thyroid removed. It helps doctors understand who might be at higher risk so they can plan better care.
Minya, Minya GovernorateAges 18–75 - NCT07063537Recruiting
Virtual reality eye test for glaucoma patients
This trial tests whether a virtual reality device can accurately measure your field of vision compared to standard tests. If you have primary open-angle glaucoma and can perform a visual field test, you may be able to participate.
Halifax, Nova ScotiaAges 18 years+ - NCT07056738Enrolling by invitation
Ganglion Cell Loss Study in Retinitis Pigmentosa
This study looks at whether a type of retinal cell (ganglion cells) degenerates in people with retinitis pigmentosa. The goal is to learn more about the progression of the disease over time.
GöttingenAges 18 years+ - NCT07046546Recruiting
Thyroid nodule embolization pilot trial
This trial tests a minimally invasive procedure that blocks blood flow to large thyroid nodules, which can shrink them and relieve symptoms like trouble swallowing or cosmetic concerns. It's an option for people with benign nodules or Graves disease who want to avoid surgery or other treatments.
ReadingAges 18 years+ - NCT07046065Recruiting
Eye test study for children ages 6 to 12
This study tests a new computer-assisted method for measuring eyeglass prescriptions in children. It may help make the eye exam process faster and more accurate.
Vila Nova de FamalicãoAges 6–12 - NCT07050095Recruiting
Virtual reality vs. medication for anxiety before eye surgery
This trial compares using a virtual reality headset against a standard anti-anxiety medication (midazolam) to help patients relax before dacryocystorhinostomy (tear duct) surgery. It aims to find a non-drug way to reduce anxiety.
CairoAges 18–65 - NCT07050498Recruiting
Can virtual reality reduce anxiety before eye surgery?
This study tests if watching a virtual reality experience can help lower anxiety in adults about to have refractive (vision-correcting) surgery. If you're feeling nervous before your procedure, this simple, drug-free approach might help you relax.
MarseilleAges 18 years+ - NCT07051720Recruiting
Comparing advanced lenses for cataract surgery
This study compares five different advanced lenses (that give a range of focus) with a standard single-focus lens for cataract surgery. It aims to see which lens provides the best overall vision.
Ahaus, North Rhine-WestphaliaAges 22–85 - NCT07048106Recruiting
Study on eye changes in people with PXE
This study uses special eye imaging to track changes caused by PXE, a rare genetic condition. It may help researchers understand how PXE affects the eyes over time.
Bonn, North Rhine-WestphaliaAges Any age - NCT07053358RecruitingEarly Phase 1
Gene therapy for wet AMD
This trial tests a new gene therapy (LX111) for people with wet age-related macular degeneration (AMD) who have already been helped by standard anti-VEGF injections. The goal is to see if one dose of LX111 can reduce the need for frequent eye injections.
ShanghaiAges 50 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.