Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT06595355RecruitingPhase 2/Phase 3
Study of eye injections with or without curcumin for diabetic eye swelling
This trial tests whether adding oral curcumin (a natural supplement) to standard eye injections (bevacizumab) improves treatment for diabetic macular edema, a swelling in the back of the eye that can affect vision.
Isfahan, Isfahan University of Medical SciencesAges 40 years+ - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06596733Recruiting
Testing a new eye ointment for dry eyes (Vit-A-Vision)
This trial tests a medical device eye ointment called Vit-A-Vision for people with dry eye disease. It aims to see if the ointment can improve symptoms and tear film stability over about a month.
CologneAges 18 years+ - NCT06598423Recruiting
Wavelength lenses for nearsighted kids
This study tests a special contact lens called 'Wavelength' to slow down nearsightedness (myopia) in kids. If your child already wears contacts and has certain levels of nearsightedness, they might be able to join.
Birmingham, AlabamaAges 7–12 - NCT07679048Recruiting
Eye focus test after close-up screen time
This study measures how quickly your eyes refocus after looking at close-up images or videos for a while. It may help researchers understand eye strain from screens.
Rochester, New YorkAges 18–35 - NCT07690813Recruiting
AI model to predict nearsightedness with a non-dilated eye exam
This study uses an AI model to predict your nearsightedness prescription using a quick, non-dilated eye exam instead of the usual dilated exam. If you are between 18 and 60, have nearsightedness, and no major eye surgeries or conditions, you may be a good fit.
JiangxiAges 18–47 - NCT03848663Recruiting
Training with visual remapping to help reading with central vision loss
This study tests whether a computer-based visual training method (“remapping”) can help people read better even when they have reduced central vision. You may benefit if your eye condition is stable and your eyes can reliably track the training on an eye-tracker.
Minneapolis, MinnesotaAges 16 years+ - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+ - NCT07468409Recruiting
JASPER Robotic System for Cataract Surgery
This trial is testing a new robotic system called JASPER to help perform cataract surgery. It looks at how well and safely the robot assists during the operation, which may help improve precision and recovery.
Makati City, National Capital RegionAges 55–80 - NCT06601101RecruitingPhase 3
Insulin drops for faster healing after corneal crosslinking
This trial tests whether insulin eye drops can help the cornea heal faster after corneal crosslinking, a procedure to treat keratoconus. It is for people with keratoconus who do not have diabetes, severe dry eye, or certain other eye conditions.
Campinas, São PauloAges 14 years+ - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06607705Recruiting
Eye pressure changes after iStent surgery with a contact lens sensor
This study tests a tiny implant (iStent inject W) that helps lower eye pressure in people with open-angle glaucoma. A special contact lens sensor will monitor your eye pressure after surgery. The goal is to see how well the implant works and how it changes your eye pressure throughout the day.
Barcelona, SpainAges 18 years+ - NCT06607848Recruiting
Comparing two new types of extended vision lens implants
This trial compares two different types of advanced lens implants that help you see at multiple distances after cataract surgery. It aims to find which one offers better vision for daily life.
Vienna, AustriaAges 21–105 - NCT06610747Recruiting
Home versus hospital care for diabetic eye swelling
This study tests whether receiving anti-VEGF injections for diabetic macular edema (DME) at home is as safe and effective as getting them in the hospital. You would use a home device to check your vision and eye scans, and a nurse would visit for injections.
Dongguan, GuangdongAges 18 years+ - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+ - NCT06616506Recruiting
AI for cataracts in high myopia
This trial uses artificial intelligence to study cataracts in people with high myopia (very nearsighted). It aims to improve diagnosis and treatment planning for cataract surgery.
Shanghai, Shanghai MunicipalityAges Any age - NCT06620809RecruitingPhase 1
Safety and efficacy of NouvSoma001 for NMOSD
This trial tests a new treatment called NouvSoma001 for neuromyelitis optica spectrum disorder (NMOSD), a condition where the immune system attacks the optic nerves and spinal cord. It looks at whether the drug is safe and helps people who have had a recent attack with severe pain, trouble walking, or bladder/bowel problems.
Wuhan, HubeiAges 18–65 - NCT06622044Recruiting
Vision therapy vs prism for small-angle eye turn
This trial compares two non-surgical treatments—vision therapy exercises and prism glasses—for people with a recent, constant inward eye turn (esotropia) of a small angle. The goal is to see which approach works better to straighten the eyes.
ShanghaiAges 10–40 - NCT06624826Recruiting
Extended depth of focus lens for cataract surgery
This study tests a new type of lens implant that helps you see clearly at multiple distances after cataract surgery. It compares two ways to set the lens: one aiming for perfect distance vision in both eyes, and another that leaves one eye slightly nearsighted to improve reading vision.
Vienna, AustriaAges 21–105 - NCT06625749Recruiting
AccuraSee lens implant to improve near vision after cataract surgery
This trial tests an artificial lens (AccuraSee IOPCL) placed inside your eye to help you see better up close and at intermediate distances after having cataract surgery. It is for people who still need reading glasses and have a specific type of monofocal lens already in their eye.
Cleveland, OhioAges 22 years+ - NCT06626516RecruitingPhase 1/Phase 2
Tebentafusp and LDT for metastatic uveal melanoma
This trial tests a combination of two drugs (tebentafusp and a liver-directed treatment called LDT) for people with uveal melanoma that has spread to the liver. The goal is to see if this combination helps shrink tumors and improve outcomes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06627244RecruitingPhase 2
Study of tebentafusp and radioembolization for uveal melanoma that spread to the liver
This trial tests whether combining a drug called tebentafusp with a procedure called radioembolization can help control uveal melanoma that has spread mainly to the liver. Radioembolization delivers tiny radioactive beads to the liver, and tebentafusp helps your immune system attack the cancer.
Miami, FloridaAges 18 years+ - NCT06628947RecruitingPhase 2
Testing KIO-301 eye injections for advanced retinitis pigmentosa
This trial tests an eye injection called KIO-301 for people with late-stage retinitis pigmentosa (a genetic eye disease that causes vision loss). The goal is to see if it can improve vision or slow further vision loss.
Sydney, New South WalesAges 18 years+ - NCT06629649Recruiting
AI-based glaucoma screening at health centers
This trial uses an AI tool to screen for glaucoma at community health centers. If you qualify, you will get a free eye check to catch glaucoma early and help researchers improve screening for high-risk groups.
Birmingham, AlabamaAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.