Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,762 recruiting studies in this area right now.
By phase
- Not applicable1,201
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- New York36
- Massachusetts35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,762 total
- NCT06161415RecruitingPhase 1
Laquinimod eye drops before vitrectomy: safety study
This trial tests a new eye drop called Laquinimod for people who are already scheduled for a vitrectomy. The drops are given before surgery to see if they are safe and how they spread in the eye.
Palo Alto, CaliforniaAges 18 years+ - NCT06294847RecruitingPhase 3
Ursodeoxycholic acid for better recovery after retinal detachment surgery
This trial tests if adding ursodeoxycholic acid (a bile acid medication) to standard surgery can protect the retina and improve vision after a retinal detachment. It's for people who need vitrectomy surgery and have a detached retina involving the macula.
ParisAges 18 years+ - NCT06219252Recruiting
Comparing lens power methods during cataract surgery
This study compares two ways to choose the right lens power during cataract surgery: one uses a special measurement during surgery, the other uses standard pre-surgery measurements. The goal is to see which method gives you better vision after surgery.
Mexico City, CuauhtemocAges 40 years+ - NCT06963684Recruiting
Glaucoma laser stability and sustainability study
This study tests whether a laser treatment helps keep eye pressure stable in people with early glaucoma or high eye pressure who have not used any eye drops or medications before. It may be a good option if you are looking for a treatment that doesn't require daily eye drops.
Coon Rapids, MinnesotaAges 40 years+ - NCT06963099Recruiting
INTACS for high astigmatism in healthy corneas
This trial tests a procedure called INTACS, which uses small plastic rings to reshape the cornea and reduce high astigmatism. It is for people whose corneas are healthy and not bulging or thinning.
SohagAges 18–60 - NCT06242379RecruitingPhase 1/Phase 2
Testing stem cell particles for retinitis pigmentosa
This trial tests whether tiny particles from stem cells, called extracellular vesicles, can help people with retinitis pigmentosa. It aims to see if these particles are safe and can improve vision.
Bangkok Noi, BangkokAges 18 years+ - NCT05502900RecruitingPhase 3
Melatonin after eye melanoma to lower spread risk
This Phase 3 study tests whether taking melatonin after treatment for uveal melanoma can reduce the chance that the cancer returns or spreads to other parts of the body. It is aimed at people with higher-risk eye melanoma features.
Stockholm, Stockholm CountyAges 18 years+ - NCT05675150Recruiting
Art-based program for adults with age-related vision loss
This trial tests whether an expressive arts-based program can help adults who have age-related macular degeneration (a common cause of vision loss) by supporting wellbeing and daily functioning. If you meet the language, vision, and health requirements, participating may help you benefit from a structured arts intervention.
Hong KongAges 50–80 - NCT06182605Recruiting
New tools for cataract surgery
This trial is testing special tools to help doctors perform cataract surgery more safely and easily. It is for people who need cataract surgery and do not have eye inflammation, high eye pressure, or other serious health issues.
Hangzhou, ZhejiangAges 18–80 - NCT07092124Recruiting
Virtual reality test for low vision rehabilitation
This study is testing a virtual reality test to help people with low vision who are starting or have started rehabilitation. The goal is to see how well the test works for different types of vision loss.
AngersAges 18 years+ - NCT06351670Recruiting
Monitoring early to moderate age-related macular degeneration with AI
This study uses artificial intelligence to track changes in the eyes of people with early or intermediate age-related macular degeneration (AMD). It aims to better understand how the disease progresses and may help doctors personalize care.
ViennaAges 55–99 - NCT07091825Recruiting
Lubricating drops for rigid gas permeable contact lens wearers
This trial tests a new lubricating eye drop for people who wear rigid gas permeable (RGP) contact lenses. The drops are meant to make wearing the lenses more comfortable and less dry.
Beijing, Beijing MunicipalityAges 8 years+ - NCT06351657Recruiting
Monitoring macular degeneration with AI to detect progression
This trial uses artificial intelligence to track changes in the eyes of people with advanced age-related macular degeneration (AMD) that has caused a specific type of damage (atrophy) in the retina. The goal is to see if AI can help detect when the disease gets worse, so doctors can personalize monitoring for each patient.
ViennaAges 55–99 - NCT07088705Enrolling by invitation
Subthreshold laser for retinitis pigmentosa
This trial tests a gentle laser treatment (SML) for people with retinitis pigmentosa (RP), an inherited eye disease that slowly causes vision loss. The goal is to see if the laser can help slow or improve vision problems like night blindness and tunnel vision.
SzczecinAges 18–70 - NCT06883123RecruitingPhase 4
Comparing two glaucoma drop combinations
This study compares two different pairs of glaucoma eye drops to see which works better. If you are currently using Cosopt and Latanoprost, you may be able to switch to Simbrinza and Rocklatan or stay on your current drops.
Springfield, IllinoisAges 18 years+ - NCT06972602RecruitingEarly Phase 1
High-dose topotecan for retinoblastoma with vitreous seeds
This trial tests a high dose of a chemotherapy drug called topotecan given directly into the eye (intravitreal injection) for children with retinoblastoma that has come back or not responded to treatment and has seeds floating in the vitreous. The goal is to save the eye when removal is the only other option.
Shanghai, ChinaAges 1–12 - NCT06973278Recruiting
SMILE vs SMILE Xtra for high myopia
This study compares two types of laser eye surgery (SMILE and SMILE Xtra) to see which works better for people with high myopia. It aims to help you understand which option might give you the best vision correction.
Shanghai, Shanghai MunicipalityAges 18–50 - NCT03821467Recruiting
Eye scan study to test a new imaging method in healthy adults
This study checks whether a specific eye-scanning technology gives consistent, repeatable results. It enrolls healthy adults to see if the test works reliably before being used more broadly.
Vienna, State of ViennaAges 18–35 - NCT03921931Recruiting
Test retinal responses to light in healthy eyes or eye disease
This is a small pilot study that measures how parts of the retina change before and after light stimulation. It may help researchers understand eye function in people with normal vision or specific eye conditions like glaucoma or dry age-related macular degeneration (AMD).
Vienna, State of ViennaAges 18 years+ - NCT05724641Recruiting
MRI test of eye blood flow in specific optic nerve conditions
This study uses a special MRI scan to measure blood flow to the eye and check how consistently the results match over time. It may help doctors better assess certain optic nerve problems, especially in people without major cardiovascular risk factors.
Brussels, Brussels CapitalAges 18 years+ - NCT06967792Recruiting
Safety of Terahertz Eye Scan for Blind Eyes
This trial tests a new scanning system that uses safe terahertz waves to look at the cornea. It's for people who are blind in one eye but have a healthy cornea, to see if the scan is safe.
Singapore, SingaporeAges 21 years+ - NCT07084883Recruiting
AI system for early AMD detection
This trial tests an AI system designed to catch early signs of late age-related macular degeneration (AMD) before it's diagnosed. It's for people who haven't yet been diagnosed with AMD or treated for retinal disease.
Richmond Hill, New YorkAges 50 years+ - NCT07085533Recruiting
A Study of Inherited Retinal Diseases
This study is looking at how inherited retinal diseases affect color vision over time. It may help researchers understand these conditions better and is a good fit for people with a known diagnosis who can describe what they see.
WuhanAges Any age - NCT07084545Recruiting
Cataract surgery lens for people with prior laser vision correction
This trial tests a special lens (CT LUCIA) for people who had laser vision correction in the past and now need cataract surgery. It aims to see how well the lens works in these patients.
Sugar Land, TexasAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,762 recruiting ophthalmology studies from the U.S. registry right now, out of 2,751 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.