Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT04258787Recruiting
Eye drop treatment for Fuchs corneal swelling
This trial studies a treatment for people with Fuchs’ dystrophy that affects the clear layer at the back of the cornea. It may help improve how clear your vision is after the cornea can no longer pump fluid out properly.
Portland, OregonAges 18 years+ - NCT04570020Recruiting
Check how well wide-view scans guide scleral lens fitting
This study tests whether a special wide-area eye scan (OCT) can help fit scleral contact lenses more accurately. It may help people who need scleral lenses because of certain cornea shape problems or after past eye surgeries.
Portland, OregonAges 18 years+ - NCT06491615Recruiting
eyeGENE study: genetics of rare eye diseases
This study collects DNA samples and medical information from people with rare inherited eye diseases and their close relatives. The goal is to learn more about the genetic causes of these conditions and improve diagnosis and care.
Bethesda, MarylandAges 1 day–120 years - NCT06489873Recruiting
Lutein, Zeaxanthin, and Fish Oil for Macular Health
This study tests whether taking daily supplements of lutein, zeaxanthin, and fish oil can improve the protective pigment in your eyes. It may help people with low macular pigment and good vision who are not already taking high doses of these nutrients.
College Station, TexasAges 18–45 - NCT06492538Recruiting
Eye changes after glaucoma angle surgery
This study looks at how your eye's drainage angle changes after glaucoma surgery. It helps doctors understand what happens to the front part of your eye after procedures like laser or surgery to open the drainage area.
Guangzhou, GuangdongAges 30–85 - NCT06467344RecruitingPhase 1/Phase 2
Testing ACDN-01 for ABCA4 Stargardt eye disease
This trial tests an experimental medicine called ACDN-01 for people with Stargardt retinopathy caused by ABCA4 gene mutations. The goal is to see if it can slow or stop vision loss in an eye with already damaged central vision.
San Francisco, CaliforniaAges 12 years+ - NCT06468397Recruiting
New device for sudden retinal detachment repair
This trial tests a new device for repairing a sudden retinal detachment that affects the central vision. It compares this system to standard surgery, and may be an option if you have a specific type of retinal tear in the upper part of your eye.
East Melbourne, VictoriaAges 50 years+ - NCT06475651Recruiting
DNA patterns in rare prenatal diseases
This study looks at DNA patterns in fetuses or children with rare genetic conditions. It aims to better understand how these patterns relate to diseases that start before birth, which could help with diagnosis and future care.
ParisAges birth–18 years - NCT06446817Recruiting
High-add lens implant study for cataract patients
This study tests a new type of lens implant designed to help with both distance and near vision after cataract surgery. It is for people aged 50 and older with cataracts in both eyes who have not had any prior eye surgery.
MarseilleAges 50 years+ - NCT06452316RecruitingPhase 1
Eye drop study for limbal stem cell deficiency
This study tests a new eye drop called CSB-001 for people with limbal stem cell deficiency (LSCD), a condition that damages the cornea. The goal is to see if the drops can help improve the health of the cornea and reduce inflammation.
Loma Linda, CaliforniaAges 18 years+ - NCT06445322Recruiting
Finding people with Stargardt disease for ACDN-01
This prescreening study looks for people with a specific genetic eye condition called Stargardt disease to see if they might be able to join a future trial for a new treatment called ACDN-01.
San Francisco, CaliforniaAges 5 years+ - NCT06451718Recruiting
A new implant for keratoconus to avoid corneal transplant
This trial tests a small metal implant placed in the cornea to treat keratoconus, a condition where the cornea thins and bulges. The goal is to see if the implant can safely improve vision and prevent the need for a corneal transplant.
Roma, RomaAges 18 years+ - NCT04319848RecruitingPhase 1
Tissue-engineered cornea transplant for specific eye swelling conditions
This Phase 1 trial tests a new, lab-made tissue transplant to improve corneal clarity in people with certain types of corneal endothelium failure (eye swelling) caused by specific conditions. The main goal is to check safety and see if vision and corneal health improve.
SingaporeAges 21–80 - NCT04396002Recruiting
Study of life movement and vision loss in older adults
This study looks at whether how far and how much you move around each day is linked to glaucoma and vision field loss in older adults. It may help researchers understand what affects vision changes over time.
Birmingham, AlabamaAges 18–100 - NCT06138509Recruiting
Serotonin levels in children with albinism
This study measures blood serotonin levels in children with albinism compared to children without the condition. It aims to learn if serotonin plays a role in albinism, which could help future treatments.
ParisAges 2–17 - NCT06450392RecruitingPhase 4
Tranexamic acid for less swelling and bruising after eye socket surgery
This study tests whether giving tranexamic acid (a medicine that helps blood clot) locally or through an IV can reduce swelling and bruising after eye socket surgery.
The Bronx, New YorkAges 18 years+ - NCT06453694RecruitingPhase 2
Efgartigimod for first-time optic neuritis
This trial tests a drug called efgartigimod for people having their first episode of optic neuritis (inflammation of the optic nerve). The goal is to see if it can help protect your vision better than standard treatment alone.
Boston, MassachusettsAges 18 years+ - NCT06455384Recruiting
Studying a digital tool for genetic testing services
This trial tests a new online tool called the Genetics Navigator, which helps people access genetic testing services more easily. If you or your child have been referred for genetic testing at Mount Sinai Hospital or SickKids in Toronto, this study may help you manage the process online.
Toronto, OntarioAges 18 years+ - NCT06429280Recruiting
Lazy Eye Treatment Registry for Luminopia Users
This registry collects information from people with lazy eye who have used Luminopia treatment for at least 12 weeks. It helps researchers learn more about how the treatment works in real life.
San Ramon, CaliforniaAges Any age - NCT05432336Recruiting
Testing better lab diagnosis for serious eye infections
This study looks at how doctors collect and test eye infection samples to get more accurate results, especially in serious cases like corneal abscess or deep eye infection. If you have signs of a complex eye infection and a sample is needed, this trial may help improve the way diagnosis is done for patients like you.
Paris, IDFAges 18 years+ - NCT06433284Recruiting
Comparing two treatments for large macular holes
This study compares two surgical methods for repairing large macular holes, a condition that affects the center of the retina and can blur vision. The goal is to see which technique works better for closing the hole and improving eyesight.
Nakhon Si Thammarat, ThasalaAges 18 years+ - NCT06429527Enrolling by invitation
Smartphone app for follow-up after cataract surgery
This trial tests whether checking your vision at home with a smartphone app (WHOeyes) and answering a few questions can safely replace a one-week in-person visit after cataract surgery. If you qualify, you'll help doctors see if app-based follow-up is convenient and reliable.
Guangzhou, GuangdongAges 50–80 - NCT06426498Recruiting
Ultrasound and temporary blind spot study
This study tests whether a focused ultrasound technique can create a temporary blind spot in the vision. Researchers hope this will help them find the right ultrasound dose for each person, with the goal of treating certain brain conditions.
Charleston, South CarolinaAges 18–70 - NCT06435000Recruiting
A study tracking Stargardt disease progression
This study follows people with Stargardt disease (a genetic eye condition that causes vision loss) over time. It aims to learn more about how the disease progresses and does not test any treatment.
San Diego, CaliforniaAges 12–65
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.