Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3130
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07169695RecruitingPhase 2
Comparing a new eye drop to cyclosporine for eye allergy in kids
This study tests a new eye drop (T1695) against cyclosporine for children with moderate to severe vernal keratoconjunctivitis, a type of eye allergy. It aims to see which treatment works better and is safer for reducing symptoms.
Kolkata, West BengalAges 4–17 - NCT07173530Recruiting
Low-level light therapy for dry eye & skin pigmentation
This study tests whether low-level light therapy can improve dry eye symptoms caused by blocked oil glands (Meibomian Gland Dysfunction). It also looks at how the treatment affects skin pigmentation under the eyes.
Houston, TexasAges 18 years+ - NCT07174739Recruiting
Testing a new treatment for nerve pain in the eye
This study tests a new non-invasive treatment (Quantum Molecular Resonance) to see if it can reduce pain and help damaged nerves in the eye heal. It may help people with long-lasting eye pain caused by nerve damage.
SingaporeAges 21 years+ - NCT07175311Recruiting
Eye changes after endophthalmitis recovery
This study looks at how blood vessels in the eye change after endophthalmitis, a severe eye infection. It may help doctors better understand recovery and improve future treatment.
Mexico CityAges 18 years+ - NCT07175909Recruiting
Tear analysis for dry eye diagnosis and management
This study looks at proteins in your tears to better understand and treat dry eye disease. You may qualify if you have dry eye symptoms and certain test results show your eyes are not functioning normally.
Hong KongAges 18–65 - NCT07176416Recruiting
Cataract surgery study using Veritas and laser technology
This study looks at how using the Veritas system during cataract surgery affects surgery time and the health of the inner layer of your cornea. It may help doctors understand how to better protect your eyes during surgery.
‘Aiea, HawaiiAges Any age - NCT07176949Recruiting
Early myopia prevention study for young children
This study tests a program to prevent or slow down early nearsightedness (myopia) in children ages 3 to 6. It aims to find out if certain eye care methods can help keep their vision healthy.
Shanghai, Shanghai MunicipalityAges 3–6 - NCT07178639Recruiting
Comparing three eye drops after cataract surgery
This trial tests three different anti-inflammatory eye drops to see which works best for pain and swelling after cataract surgery. You may join if you are scheduled for cataract surgery only, and you can apply the drops yourself or have help.
KolínAges 18 years+ - NCT07179055RecruitingPhase 2
A study of VSJ-110 for dry eye disease
This trial tests a new eye drop called VSJ-110 to see if it is safe and effective for treating dry eye, compared to a placebo (inactive drops). It lasts 8 weeks and may help if you have dry eye symptoms.
Newport Beach, CaliforniaAges 18 years+ - NCT07183891Recruiting
Testing AI to analyze eye surgery results
This trial tests whether large language models can accurately analyze eye surgery data and predict how well patients see after surgery. It focuses on patients who had good vision and stable lens implants one month after cataract surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07185347RecruitingPhase 3
Fampridine for SCA27B ataxia study
This trial tests if fampridine, a medication, can improve walking and coordination in people with SCA27B, a specific inherited ataxia. It compares fampridine to a placebo over a period of time.
AngersAges 18 years+ - NCT07185256RecruitingPhase 1/Phase 2
Gene therapy for Best disease retinal trial
This trial tests a gene therapy called OPGx-BEST1 injected under the retina to treat vision loss from Best vitelliform macular dystrophy or a related condition. It may help people with advanced disease who have a specific genetic change in the BEST1 gene.
Los Angeles, CaliforniaAges 18 years+ - NCT07185971Recruiting
Vision training system for chronic vision loss after brain injury
This study tests a device called PAVE that may help improve vision in people who have lost part of their sight due to stroke, brain injury, or brain surgery. It is for those with ongoing vision problems, not those with eye diseases.
Cedar Rapids, IowaAges 21–80 - NCT07191847RecruitingPhase 4
Stem cell eye drops for dry eye disease
This trial tests whether stem cell fortified eye drops can improve tear film stability, tear volume, and dry eye symptoms. If you have dry eye disease and haven't had eye surgery or certain other eye conditions, you may be able to join.
GizaAges 18–80 - NCT07201298Recruiting
Comparing laser eye surgery methods for nearsightedness
This study compares a new type of laser surgery (ray-tracing guided) to three other standard laser methods for correcting nearsightedness with or without astigmatism. It aims to see which approach provides the best vision correction.
Draper, UtahAges 22–50 - NCT07202494Recruiting
Brain aging and resilience MRI study
This study uses powerful MRI scans to understand how the brain ages and why some people stay healthy while others develop neurological diseases like multiple sclerosis or Alzheimer's. It compares healthy volunteers to people with certain conditions, and all participants get a detailed brain MRI.
MarseilleAges 18–90 - NCT07203391RecruitingPhase 1
Tebentafusp and roginolisib for uveal melanoma
This trial tests a combination of two drugs, tebentafusp and roginolisib, for people with uveal melanoma that has spread or can't be removed. It aims to improve how long the immune system stays active against the cancer.
Sydney, New South WalesAges 18 years+ - NCT07205887RecruitingPhase 2
Study of EYE103 for wet AMD or macular edema after BRVO
This trial tests an investigational drug called EYE103 injected into the eye to treat two conditions: wet age-related macular degeneration (AMD) or macular edema following a branch retinal vein occlusion (BRVO). It looks at how safe and effective the drug is for people who have not had treatment before or have not responded well to previous treatments.
Scottsdale, ArizonaAges 18 years+ - NCT07206238Recruiting
Orbital blood vessel inflammation in optic nerve disease
This study uses MRI scans to look at inflammation in blood vessels around the eye in two conditions: giant cell arteritis (GCA, a type of blood vessel inflammation) and ischemic optic neuropathy (a condition where the optic nerve doesn't get enough blood). The goal is to better understand how inflammation affects the optic nerve and vision, which could help guide future treatments.
Glostrup MunicipalityAges 50 years+ - NCT07209410RecruitingPhase 4
Eye drops to reduce redness from glaucoma treatment
This trial tests if adding brimonidine eye drops can reduce eye redness caused by the glaucoma drops you are currently taking. It may help if you have been using netarsudil/latanoprost drops and have noticed redness.
Kansas City, MissouriAges 18–65 - NCT07211776RecruitingPhase 3
Study of ZL-1109 for active thyroid eye disease
This trial tests a new drug called ZL-1109 for people with active, moderate to severe thyroid eye disease (TED). It aims to see if the drug can reduce symptoms like bulging eyes and help patients feel better without using steroids.
BeijingAges 18–75 - NCT07217678RecruitingPhase 4
Eye drops and surface damage in glaucoma treatment
This study looks at how certain glaucoma eye drops affect the surface of your eye. It tests a new implant that may reduce damage and improve comfort.
Miami, FloridaAges 18 years+ - NCT07218731Recruiting
Multifocal contact lenses vs reading glasses for presbyopia
This study compares multifocal contact lenses to single vision lenses and reading glasses for people over 40 who need help seeing up close. It aims to find which option provides a better experience for presbyopia (age-related blurry near vision).
Columbus, OhioAges 40 years+ - NCT07218783RecruitingPhase 3
Testing a new glaucoma implant with cataract surgery
This trial tests a new implant that releases medicine for glaucoma while you have cataract surgery. It may help lower eye pressure without using daily drops.
Houston, TexasAges 22 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,919 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.