Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06569758RecruitingPhase 1
A study of GenSci098 for active thyroid eye disease
This study tests a new medication called GenSci098 for people with active thyroid eye disease. It aims to reduce eye symptoms like redness, swelling, and bulging, and improve quality of life.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06581406RecruitingPhase 2/Phase 3
RP2 with nivolumab for untreated uveal melanoma
This clinical trial tests a new treatment called RP2 (a virus that attacks cancer cells) combined with nivolumab (an immunotherapy drug) for people with metastatic uveal melanoma who have never had immunotherapy before. It aims to see if this combination can shrink tumors and improve outcomes.
Scottsdale, ArizonaAges Any age - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06557460RecruitingPhase 2
Cell implant for advanced dry age-related macular degeneration
This trial tests a patch of retinal cells implanted under the retina to see if it can slow or stop vision loss from advanced dry AMD (geographic atrophy). It may help people whose central vision is already affected.
Huntington Beach, CaliforniaAges 55–90 - NCT06555289Recruiting
New lens implant after prior laser vision correction
This study tests a new type of artificial lens (Clareon PanOptix Pro) for people who have had LASIK or PRK in the past and now need cataract surgery. It aims to see how well the lens works for these patients, potentially improving vision after surgery.
Albuquerque, New MexicoAges 45 years+ - NCT06565572Enrolling by invitationEarly Phase 1
Antisense drug for PCARP disease caused by FLVCR1 mutation
This trial tests a new drug called an antisense oligonucleotide (a type of genetic medicine) for people with a specific form of inherited eye disease called PCARP, which is caused by changes in the FLVCR1 gene. The goal is to see if the drug can slow or stop vision loss.
Aurora, ColoradoAges Any age - NCT06566339Recruiting
Robotic eye scan for emergency room patients
This study tests a new robotic device that uses light scans (OCT) to look at the front part of your eye. It may help find problems like redness or a foreign body without needing traditional exams.
Durham, North CarolinaAges 18 years+ - NCT06550674Recruiting
Genetic study for uveal melanoma risk
This study looks for new inherited genes linked to uveal melanoma (an eye cancer). If you have this cancer and don't already have a known genetic cause, you may be able to help find new genes that affect cancer risk.
Clermont-Ferrand, Puy-de-DômeAges 18 years+ - NCT04424719Recruiting
Follow-up study for high-risk eye melanoma after treatment
This study follows people with high-risk uveal (eye) melanoma after their initial treatment to better understand relapse risk. It may help your care team track you more closely using scheduled visits and blood tests.
ParisAges 18 years+ - NCT06549023Recruiting
One session vs multiple sessions of laser for diabetic eye disease
This study compares having laser treatment for diabetic eye disease in one session versus spreading it over multiple sessions. The goal is to find out if one approach is better for your eyes and easier for you.
MölndalAges 18 years+ - NCT06548607RecruitingEarly Phase 1
CAR-T therapy for autoimmune diseases
This early-phase trial tests a new CAR-T cell therapy that targets CD19 or both CD19 and BCMA to treat several autoimmune diseases like lupus, scleroderma, and vasculitis. It aims to calm the overactive immune system with a single infusion of your own engineered cells.
Bengbu, AnhuiAges 18–70 - NCT06541704RecruitingPhase 3
Study of pozelimab with cemdisiran for geographic atrophy
This trial tests a combination of two study drugs (pozelimab and cemdisiran) given as a shot under the skin to slow the progression of geographic atrophy, a type of advanced dry age-related macular degeneration that causes blind spots in central vision.
Chandler, ArizonaAges 50–85 - NCT06536062Recruiting
Cord blood and platelet plasma for dry macular degeneration
This trial tests if a treatment made from umbilical cord blood and platelet-rich plasma can help people with dry age-related macular degeneration. The treatment is given as an injection into the eye, and the goal is to see if it slows vision loss or improves sight.
Rome, RomeAges 65 years+ - NCT06527326Recruiting
Gut bacteria and central serous chorioretinopathy study
This study looks at the link between gut bacteria and central serous chorioretinopathy (CSC), a condition where fluid builds up under the retina. It may help us understand why some people get CSC and find better ways to treat it.
Hanzhou, ZhejiangAges Any age - NCT06524882RecruitingPhase 3
Special glasses for lazy eye in children 8 to 12 years old
This trial tests if special movies or games viewed through a headset can improve vision in children with lazy eye (amblyopia). It compares these treatments to wearing glasses alone.
Birmingham, AlabamaAges 8–12 - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06523504RecruitingPhase 1/Phase 2
Atropine Drops with Special Glasses for Myopia in Children
This trial tests whether a combination of low-dose atropine eye drops (0.02% or 0.04%) and special glasses (called DIMS) can slow down the worsening of moderate to high myopia in children aged 6 to 12.
Tianjin, Tianjin MunicipalityAges 6–12 - NCT06514612RecruitingPhase 3
Eye drop study for droopy eyelids in adults
This study tests a new eye drop (oxymetazoline) to see if it can help lift droopy eyelids in adults. To join, you must have a certain amount of eyelid droop and some vision loss in your upper field of view, and you should feel that the droop bothers you enough to want treatment.
PardubiceAges 18–75 - NCT05676580Recruiting
Study of risk factors and vision changes in keratoconus
This study looks at what leads to keratoconus and how it progresses over time. It may help doctors better predict worsening vision and plan earlier care.
Montpellier, OccitanieAges 10–40 - NCT06511700Enrolling by invitation
Nurse-led eye injections: a new care approach
This trial tests whether specially trained nurses can safely give eye injections instead of doctors. It may make treatment quicker and easier for people who need regular injections for eye conditions.
Sabadell, BarcelonaAges 18 years+ - NCT06502015Recruiting
Biomarkers in nervous system autoimmune diseases
This study looks for biomarkers (biological clues) in people with autoimmune diseases of the nervous system. It aims to discover better ways to diagnose and treat these conditions.
WuhanAges 18 years+ - NCT03760432Recruiting
Cornea strengthening study for keratoconus using collagen cross-linking
This trial studies collagen cross-linking, a procedure meant to strengthen a weakened cornea in people with keratoconus. It may help slow the bulging/weakening of the cornea and improve vision, and the study also uses special imaging to check changes over time.
Portland, OregonAges 18 years+ - NCT03504800Recruiting
Using OCT scans to diagnose irregular corneas
This study tests whether a special eye scan called OCT can better identify causes of irregular cornea shape. Results may help doctors sort out different cornea problems so treatment choices, like certain procedures, can be more targeted.
Portland, OregonAges 14–85 - NCT03809585Recruiting
Study of iris tumors and healthy eyes
This observational study looks at eyes with iris tumors and compares them to eyes without iris problems. The goal is to better understand how iris circulation and related eye measurements differ, which may help future care.
Portland, OregonAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.