Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT07249216Recruiting
Eye fluid study for wet AMD treatment response
This study looks at eye fluid from people with untreated wet AMD to find out why some don't respond well to standard injections. The goal is to improve future treatments.
SingaporeAges 50 years+ - NCT07250139Recruiting
Comparing Ziplyft vs. eyelid surgery for upper eyelid rejuvenation
This study compares a new non-surgical treatment called Ziplyft with traditional eyelid surgery (blepharoplasty) to reduce extra skin on the upper eyelids. It may be a good option for people who want to refresh their eyes without a full surgery.
Oxford, North CarolinaAges 35 years+ - NCT05463289Recruiting
AI helps children with diabetes get eye exams
This study tests an AI-based way to help check children’s eyes for signs of diabetic retinopathy (diabetes-related eye disease). It may improve how quickly and consistently eye screening is done for kids with diabetes.
Baltimore, MarylandAges 8–21 - NCT06701721RecruitingPhase 1
Study of THN391 eye injection for diabetic macular edema
This trial tests an experimental eye injection called THN391 for people with diabetic macular edema, a condition that causes vision loss due to swelling in the back of the eye. The study aims to see if the treatment is safe and may help improve vision.
Parramatta, New South WalesAges 18–80 - NCT04401982RecruitingPhase 4
Testing eye drops for blood flow in high eye pressure and glaucoma
This study tests whether three different eye drop treatments (netarsudil, latanoprost, or both together) can improve blood flow to the white part of the eye and the retina. It may help people with high eye pressure or who are glaucoma suspects better understand how these treatments work.
Baltimore, MarylandAges 18 years+ - NCT07680244Recruiting
Testing a new tool to see retina in eye scans
This trial is testing a new software tool that helps doctors see and assess different parts of the retina in eye scans. It aims to see how well the tool works in people with and without certain retina conditions.
Tucson, ArizonaAges 18 years+ - NCT05726058Recruiting
Imaging eye blood flow to assess glaucoma
This study uses special imaging to look at blood flow in the eye to help assess or better understand glaucoma. You may be eligible if you’re an adult with eye exams that fit the study’s specific eye-health and imaging requirements.
Baltimore, MarylandAges 18–88 - NCT07682025Enrolling by invitation
Imaging and eye model for PVR study
This study uses eye scans and computer models to better understand and predict a condition called proliferative vitreoretinopathy (PVR), which can cause vision problems after eye surgery. If you already took part in specific studies that collected your eye images, this trial may analyze those images with artificial intelligence (AI).
LondonAges 18 years+ - NCT07255859Recruiting
Home monitoring for wet AMD using a webcam
This study tests a home monitoring system using a webcam to check for signs of wet AMD returning. It may help you manage your condition between doctor visits and catch problems early.
SingaporeAges 50–99 - NCT07257172Recruiting
New way to fix a shifted lens using iris hooks
This trial tests a special technique to reposition and secure the eye's lens without stitches. It uses small hooks on the iris to hold the lens in place, which may help people with a partially dislocated lens avoid more complex surgery.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07257185RecruitingPhase 3
MHB018A for Chronic Thyroid Eye Disease
This study tests a new medication called MHB018A for people with chronic Thyroid Eye Disease (TED) that is moderate to severe. It aims to see if the drug can help improve symptoms and quality of life over time.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07259928RecruitingPhase 2
Testing ANXV for diabetic retinopathy or retinal vein occlusion
This trial tests a new drug called ANXV (Annexin A5) to see if it is safe and can help people with diabetic retinopathy or a recent retinal vein occlusion. The goal is to reduce eye damage and improve vision.
LondonAges 18 years+ - NCT07260695RecruitingPhase 4
Odyssey Lens Study for Post-LASIK Cataract Patients
This trial tests a new type of lens implant (Odyssey IOL) for people who have had LASIK surgery and now have cataracts. It aims to see how well the lens works after cataract surgery in both eyes.
Venice, FloridaAges 50 years+ - NCT07261345RecruitingEarly Phase 1
CAR-T cell therapy for hard-to-treat Graves' disease
This early-phase trial tests whether specially engineered immune cells (called CAR-T) can treat Graves' disease that hasn't responded to standard medication. It's for people with active, hard-to-control Graves' who have the TRAb antibody.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07262476RecruitingPhase 3
Extension study of MHB018A for thyroid eye disease
This study tests a longer-term use of MHB018A for people with thyroid eye disease who did not fully respond to treatment in a previous study. It aims to see if further treatment can help improve eye bulging and other symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07265388Recruiting
Testing a scoring system for Fuchs dystrophy and cataract surgery
This study tests a scoring system to predict how well people with Fuchs dystrophy do after cataract surgery. It may help doctors plan better treatment for your cornea and lens.
Madrid, MadridAges 40 years+ - NCT07266948RecruitingPhase 4
How TRYPTYR eye drops affect dry eye symptoms and daily life
This study tests a new eye drop called TRYPTYR to see if it can improve quality of life and daily tasks for people with dry eye disease who are unhappy with their current treatment, Restasis. Participants will stop using Restasis and switch to TRYPTYR for about 4 weeks.
Pittsburg, KansasAges 18–75 - NCT07275021Recruiting
Brain Injury & Vision Screening in Newborns
This study looks for early signs of vision problems in babies who had brain injuries around the time of birth. It aims to help doctors better identify and predict these issues.
Boston, MassachusettsAges 7 months–10 months - NCT07276087Recruiting
Physical and Mental Health in Takayasu Arteritis and Behçet's Disease
This study compares physical and mental health in people with Takayasu arteritis or Behçet's disease to healthy volunteers. It aims to better understand how these conditions affect day-to-day life and well-being.
Denizli, DenizliAges 18 years+ - NCT07276217Recruiting
Cataract surgery lens registry study
This trial is a registry for people having cataract surgery in both eyes. It collects information on different types of artificial lenses used to improve vision, and follows up to see how well they work.
WarsawAges 18 years+ - NCT07276386RecruitingPhase 2
Combination therapy for metastatic uveal melanoma
This trial tests a two-part treatment for uveal melanoma that has spread to the liver. First, you get a liver-directed chemotherapy (melphalan) through a special procedure called PHP, then you receive an immunotherapy drug (tebentafusp) that helps your immune system attack the cancer.
Tampa, FloridaAges 18 years+ - NCT07278843Recruiting
Understanding vision loss in Usher syndrome type 1B
This study follows people with Usher syndrome type 1B over time to learn how vision loss progresses. It also tests new ways to measure functional vision, which may help design future treatments.
Paris, Île-de-France RegionAges 3–75 - NCT07281456RecruitingPhase 2
Testing a new oral drug for Sjögren's disease safety
This study tests the safety of a daily pill called Tofacitinib for adults with mild-to-moderate Sjögren's disease. It aims to see if this drug helps manage symptoms when other treatments haven't worked well.
Bethesda, MarylandAges 18–75 - NCT07281742Recruiting
Amblyopia treatment for children aged 8 to 12
This trial tests a new treatment for children aged 8 to 12 with lazy eye (amblyopia) who have stopped standard treatments. The goal is to see if this therapy can improve vision in the weaker eye.
Dallas, TexasAges 8–12
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.