Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT06309316Recruiting
Person-centered care for Graves' disease
This trial tests if a person-centered care approach improves well-being for people newly diagnosed with Graves' disease. You may receive extra support focused on your personal needs and goals.
GothenburgAges 18–65 - NCT06315556Recruiting
Study of Eylea for preterm babies with retinopathy of prematurity in the UK
This study collects information on how the medicine Eylea is given to preterm babies with retinopathy of prematurity (an eye problem in premature infants) using a special dosing device. The goal is to see how the treatment works in everyday hospital care.
Multiple LocationsAges Up to 1 year - NCT06312644Recruiting
Study of Ultomiris safety during pregnancy
This study looks at the safety of the medication Ultomiris when taken during pregnancy or breastfeeding. If you are pregnant and currently taking Ultomiris for an approved condition, this research will help gather information on how it affects you and your baby.
Boston, MassachusettsAges Any age - NCT06311617Recruiting
Eye Blood Vessel Changes During Pregnancy
This observational study monitors changes in the blood vessels of your retina (the light-sensitive tissue at the back of the eye) during pregnancy. Researchers want to see how pregnancy affects the eyes, which might help better understand overall health.
Nashville, TennesseeAges 18 years+ - NCT06280755Recruiting
AI-assisted MS care study
This study looks at how artificial intelligence (AI) can help doctors care for people with multiple sclerosis (MS) and other similar conditions. It uses existing medical data to see if AI can improve treatment decisions.
Prague, Praha 2Ages 18 years+ - NCT06292650RecruitingEarly Phase 1
Gene therapy ZM-02 for advanced retinitis pigmentosa
This experimental gene therapy (ZM-02) is designed for people with advanced retinitis pigmentosa who have very poor vision (counting fingers or worse). It aims to see if the treatment is safe and can improve vision by replacing a faulty gene in the retina.
Beijing, Beijing MunicipalityAges 18–65 - NCT06294613Recruiting
Robotic eye surgery for vitreoretinal conditions
This study tests a robotic system to assist eye surgery for certain retina and vitreous conditions, such as bleeding in the eye or a wrinkle on the macula. It aims to see if the robot can safely help improve vision.
Ghent, East FlandersAges 18–85 - NCT06275620Enrolling by invitationPhase 2
Testing a gene therapy for X-linked retinitis pigmentosa in males
This trial tests two doses of a gene therapy (AGTC-501) in males who already had one eye treated with a similar gene therapy for X-linked retinitis pigmentosa caused by RPGR mutations. The goal is to see if the treatment is safe and can help preserve or improve vision.
Jacksonville, FloridaAges 12 years+ - NCT06285539RecruitingPhase 2
Testing a drug for rare inflammatory diseases
This trial is testing a new drug (a JAK inhibitor) for people with rare inflammatory diseases like Behçet's, myositis, or IgG4-related disease that hasn't improved with standard treatments. The goal is to see if it can help control symptoms and reduce inflammation.
AmsterdamAges 18–65 - NCT06278974Recruiting
Comparing myopia treatments for kids: glasses vs ortho-k
This study compares three ways to slow down nearsightedness in children: special glasses (defocus lenses), regular glasses, and orthokeratology contact lenses (worn overnight). It aims to find which works best for kids who have never worn glasses before.
Shenyang, LiaoningAges 7–17 - NCT06293196Recruiting
Acupoint eye massage trial for healthy people
This study tests whether massaging acupoints around the eyes can improve eye health measurements. It is only for healthy people with no eye problems, recent surgeries, or caffeine before the test.
Wuhan, HubeiAges 18–80 - NCT06289491Recruiting
Hydrus Microstent vs Goniotomy during cataract surgery
This study compares two procedures done during cataract surgery: placing a tiny stent (Hydrus Microstent) or performing a goniotomy (a small cut in the eye's drainage tissue). Both aim to lower eye pressure in people with mild to moderate open-angle glaucoma.
Boston, MassachusettsAges 40–85 - NCT06293560Recruiting
Genetic study of rare eye conditions in children
This study looks at the genetic causes of rare eye conditions (microphthalmia, anophthalmia, and coloboma). It helps researchers understand why these conditions happen and how they run in families.
Houston, TexasAges Any age - NCT06291818Recruiting
Magnetic device for treating eye exposure
This study tests a new magnetic device that sticks to your eyelid to help protect the eye when you can't fully close it. It may be an option if you have a recent scratch on your eye and trouble closing your eyelids.
Chicago, IllinoisAges 18–80 - NCT04187443RecruitingPhase 1
Drug MS-553 for diabetic eye swelling with reduced vision
This Phase 1 trial tests MS-553 to see how it works and how safely it can be given to people with diabetic retinopathy causing central macular swelling (macular edema). You may be considered if your vision and eye scan results match, and if you can follow frequent study visits.
Changsha, HunanAges 18 years+ - NCT05632887Recruiting
Testing how eyeliner changes eye tears
This study compares how eyeliner affects your tears—like tear makeup, how much your eyes produce, and how long the tear layer stays stable. You might help researchers understand whether eyeliner use impacts eye comfort or dryness.
Wuhan, HubeiAges 20–35 - NCT06257082Recruiting
Video education for diabetic eye screening in Latinx communities
This study tests video-based education to help Latinx people with diabetes get regular eye exams, which can prevent vision loss. You may be able to join if you are Hispanic or Latino and have diabetes.
Madison, WisconsinAges 18 years+ - NCT06274593Recruiting
Eye Imaging Study for Advanced Glaucoma
This study uses a special imaging test (OCT angiography) to look at blood flow around the optic nerve in people with advanced glaucoma. It aims to better understand how glaucoma affects eye circulation, which may help improve future care.
Nantes, NantesAges 18 years+ - NCT06271330Recruiting
Switching older injections to faricimab for wet AMD
This study looks at people with wet AMD who have been getting regular eye injections of either aflibercept or ranibizumab for over a year. The goal is to see what happens when they switch to a newer injection called faricimab.
Nantes, NantesAges 18 years+ - NCT06261346Recruiting
Growth factors in corneal transplant surgery
This study tests whether adding a special growth factor solution to the fluid used during corneal transplant surgery helps the transplant heal better. It is for patients undergoing a specific type of corneal transplant called DSEK or DMEK.
Miami, FloridaAges 18–80 - NCT06273748Recruiting
Study on chronic eye inflammation in children
This study looks at children with long-term eye inflammation that is not caused by an infection. It aims to learn more about the condition and how to better help patients.
Kansas City, KansasAges 1–16 - NCT06258707Recruiting
Testing a new artificial lens for cataract surgery
This study tests a new artificial lens (LuxBoost IOL) designed to safely improve vision after cataract surgery in both eyes. It may be a good option if you have cataracts in both eyes, have healthy eyes with no prior surgery, and need a standard lens power.
MontaubanAges 50 years+ - NCT06257355RecruitingPhase 1
Testing a new eye drop for corneal scars
This trial tests a new eye drop to see if it can safely and effectively reduce corneal scars. It is for people who have a recent corneal injury (within the last month) that resulted in a scar that affects their vision.
Loma Linda, CaliforniaAges 18–80 - NCT04628663Recruiting
Dexmedetomidine and eye pressure during spine surgeries
This study looks at whether a specific anesthesia-related medicine (dexmedetomidine) affects eye pressure during planned spine operations done with the patient lying face-down under general anesthesia. It may help doctors choose safer anesthesia to reduce risks related to eye pressure changes.
Athens, AtticaAges 18–90
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.