Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT05372861Recruiting
Eye test using nanopore sequencing for endophthalmitis
This trial studies endophthalmitis, an infection inside the eye, using a genetic test to better understand what’s causing it. It may help doctors learn more about the infection and guide treatment decisions in the future.
Graz, StyriaAges 18–99 - NCT06246149RecruitingPhase 3
Tebentafusp after treatment for high-risk eye melanoma
This trial tests a new drug called tebentafusp given after standard treatment (surgery or radiation) for high-risk uveal melanoma that hasn't spread. The goal is to see if it helps prevent the cancer from coming back.
Lake Success, New YorkAges 18 years+ - NCT06246136Recruiting
Laser treatment for glaucoma during cataract surgery
This study tests a new laser treatment (ELIOS) for people with open-angle glaucoma who also need cataract surgery. It aims to see if the laser is safe and effective at lowering eye pressure while removing the cataract.
LeuvenAges 40 years+ - NCT06235567Enrolling by invitationPhase 1/Phase 2
Eye drop vs. insert for recovery after cornea crosslinking
This trial compares two ways to manage inflammation after corneal crosslinking for keratoconus: a tiny steroid insert placed in the tear duct versus standard steroid eye drops. It aims to see which option is easier and works just as well.
San Francisco, CaliforniaAges 13–64 - NCT06237127Recruiting
Goji berries vs. fiber for age-related macular degeneration
This study compares the effects of eating goji berries versus taking fiber wafers on age-related macular degeneration (AMD). It looks at whether goji berries or fiber can help slow down the eye condition, especially for people with a family history of AMD.
Sacramento, CaliforniaAges 65–95 - NCT06232616Enrolling by invitation
Eye surgery with steroid implant for membrane-related swelling
This study tests combining vitrectomy (surgery to remove the membrane from the retina) with a dexamethasone implant (a tiny steroid that is placed inside the eye to reduce swelling) for people with a specific type of eye membrane and fluid buildup in the center of the retina.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT06241209Recruiting
Vision rehab for hemianopsia after stroke or brain injury
This study tests a vision rehabilitation program for people who lost part of their vision on the same side in both eyes after a stroke or brain injury. The program uses flashing lights to help retrain your brain, so it is important that you do not have seizures triggered by lights.
Edmonton, AlbertaAges 18 years+ - NCT06227962Enrolling by invitation
Thinking and quality of life in retinoblastoma survivors
This study looks at how retinoblastoma and its treatment affect thinking skills and quality of life over time. It may help doctors better support survivors and their families.
Amsterdam, North HollandAges 6 months–35 years - NCT06221592Enrolling by invitation
New glasses for slowing myopia in children
This study is testing the safety and comfort of new glasses with special lenses designed to slow down nearsightedness in children. It compares differences between the new lenses and regular lenses, and the child will wear them for a period of time to see how they feel and if there are any concerns.
Shanghai, Shanghai MunicipalityAges 6–14 - NCT06227299Enrolling by invitation
Long-term study of glaucoma surgeries and lasers
This study follows patients over time to see how well different glaucoma treatments (medications, laser, or surgery) work. It may help doctors learn which treatments are best for managing glaucoma and high eye pressure.
Lausanne, Canton of VaudAges 18 years+ - NCT06227611Recruiting
Testing vision grids for glaucoma patients
This trial compares different visual field test patterns to detect central vision loss in glaucoma patients who already show thinning of retinal cells. The goal is to find which test pattern works best for early detection.
RomeAges 18 years+ - NCT06220474Recruiting
Radiofrequency treatment for stubborn dry eye
This trial tests a non-invasive radiofrequency treatment for people with meibomian gland dysfunction (a type of dry eye) that hasn't improved with standard treatments. It aims to see if this therapy can safely help your eyes feel better.
Hong KongAges 18 years+ - NCT06213649RecruitingPhase 3
Ulcer treatment trial for active eye infection
This trial tests a new treatment for people who still have eye inflammation after 1 month of standard treatment for a parasitic eye infection (acanthamoeba keratitis). It aims to find a better way to control the infection and reduce inflammation.
Irvine, CaliforniaAges 8 years+ - NCT05847387Recruiting
Checking endothelial cell health before corneal transplant
This study tests how well a patient’s corneal lining cells are preserved before corneal transplantation, and uses that to guide the transplant approach. It may help improve transplant planning and outcomes for people who need treatment for conditions like keratoconus or Fuchs endothelial dystrophy.
EdegemAges 18 years+ - NCT06191094Enrolling by invitationPhase 4
Vabysmo before eye surgery for bleeding in diabetes
This trial tests if an injection of Vabysmo (faricimab) given before surgery can help people with eye bleeding from diabetic retinopathy. It aims to reduce blood in the eye and improve surgery outcomes.
Aurora, ColoradoAges 18 years+ - NCT06204926Recruiting
AI predicts SMILE surgery results and risks
This trial tests if an AI program can predict complications and recovery after SMILE eye surgery for nearsightedness. It may help you understand your risks if you are a candidate for this surgery.
Nanchang, JiangxiAges 18–45 - NCT06190301Recruiting
Comparing injection vs. radiation for eye lymphoma
This trial compares two treatments for a slow-growing eye lymphoma called MALT lymphoma: a targeted injection (rituximab) directly into the tumor versus low-dose radiation. The goal is to see which is safer and works better, while avoiding whole-body side effects.
Guangzhou, GuangdongAges 18–75 - NCT06190626Recruiting
A study of eye disease in Zellweger spectrum disorder over time
This study follows people with Zellweger spectrum disorder (ZSD) to understand how their eye condition develops over time. It aims to help doctors treat the disease better in the future.
Rochester, New YorkAges Any age - NCT03713268Recruiting
Using a scan to guide eye surgery in real time
This trial tests whether a special eye scan (OCT) can help guide eye surgery during the operation. It may improve how surgeons see and target the exact eye structures they need to treat.
Durham, North CarolinaAges 4 weeks+ - NCT05716945RecruitingPhase 4
OPTIMISE Study for patients getting cornea transplant surgery
This trial looks at how to manage medicine around DMEK corneal transplant surgery to improve eye outcomes and safety. It may help people having this specific type of cornea transplant by testing an approach in the time after surgery.
Apeldoorn, GelderlandAges 21 years+ - NCT06163989Recruiting
Eye drops for gamers with dry eyes
This trial tests whether lubricating eye drops can help keep gamers' eyes comfortable and healthy. If you play games for 2+ hours a day and have dry eyes, you might be able to join.
Birmingham, West MidlandsAges 18 years+ - NCT06167642Enrolling by invitation
Retinal health and nerve markers in MS patients taking ofatumumab
This study looks at how ofatumumab (Kesimpta) affects the back of the eye (retina) and certain nerve proteins in the blood in people with relapsing multiple sclerosis. It may help doctors understand how well the medication is protecting the eyes and nerves.
Baltimore, MarylandAges 18–70 - NCT06134219Recruiting
Course for brain fatigue after Graves' disease
This study tests a course designed to help with brain fatigue (mental tiredness) that can happen after Graves' disease. It is for people whose thyroid levels are stable but who still struggle with fatigue.
GothenburgAges 18–72 - NCT06139523Recruiting
Improving eye imaging in adults and children
This study aims to improve how we take pictures of the back of the eye (called OCT imaging) in both healthy adults and children. It will help doctors get better images to diagnose and manage eye conditions.
Durham, North CarolinaAges Any age
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.