Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,819 recruiting studies in this area right now.
By phase
- Not applicable1,253
- Phase 3132
- Phase 2121
- Phase 1120
- Phase 492
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract89
- Myopia89
- Diabetic Retinopathy52
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Ocular Hypertension22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California141
- Arizona66
- Texas41
- Maryland39
- Massachusetts34
- New York34
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania20
Recruiting studies1,819 total
- NCT06522867Recruiting
Measuring eye pressure after vitreoretinal surgery
This study compares three different devices (Goldmann, Icare, and Accupen) to measure eye pressure after vitreoretinal surgery. It aims to find the most accurate and comfortable method for patients.
Québec, QuebecAges 18 years+ - NCT07447973Recruiting
AI eye test for multiple eye diseases
This trial uses artificial intelligence to analyze eye images and help diagnose and prioritize eye conditions. It could help find the right treatment faster.
Guangzhou, GuangdongAges 18 years+ - NCT06498206Recruiting
Augmented reality training vs patching for lazy eye
This study compares using a special augmented reality (AR) headset versus wearing a classic eye patch to treat lazy eye (amblyopia). It is for people ages 5–55 whose weaker eye still has room to improve even after wearing glasses.
ShanghaiAges 5–55 - NCT06465056RecruitingPhase 2
Botox for eyebrow lift scar healing
This study tests whether injecting Botulinum Toxin A (Botox) into the scar from an eyebrow lift surgery helps the scar heal better. Participants will be people who are already planning to have a direct eyebrow lift.
São PauloAges 18 years+ - NCT06322433Recruiting
Follow-up study for severe nearsightedness
This study follows people with high myopia over time to monitor their eye health. It aims to better understand how very nearsighted eyes change.
MilanAges 18 years+ - NCT06450470RecruitingPhase 3
Amniotic membrane after crosslinking for progressive keratoconus
This trial tests if placing a special freeze-dried amniotic membrane on the eye after crosslinking surgery helps improve healing and comfort for people with progressive keratoconus, a condition where the cornea thins and bulges.
BrestAges 18–65 - NCT06429969Recruiting
Vitreous fluid chemicals in eye diseases
This study looks at the chemicals in the fluid inside your eye (vitreous) using a special scan. It aims to find patterns that might help doctors understand certain eye diseases better.
Wuhan, HubeiAges 40–90 - NCT05728476Recruiting
Compare eye surgery plus peeling versus anti-VEGF injections
This trial compares a minimally invasive eye procedure (vitrectomy with peeling) versus anti-VEGF injections to treat new diabetic macular edema in people who have not had treatment yet. It looks at which option improves vision and eye swelling for people with diabetes.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT03666052Enrolling by invitation
Study for kids with severe nearsightedness in Shanghai
This study registers children and teens in Shanghai who have significant nearsightedness, to better track eye health over time. It may help researchers understand why high myopia develops and how to prevent or monitor complications.
Shanghai, Shanghai MunicipalityAges 4–18 - NCT07679477Enrolling by invitation
Myopia control study for university students with special glasses
This study tests whether special spectacle lenses (called DIMS-TED) can slow down the progression of myopia (nearsightedness) in university students. It is for students whose eyes are still growing and who are willing to wear the glasses as assigned.
Bradford, West YorkshireAges 18–23 - NCT06448468Recruiting
Eye microbes in dry eye after LASIK
This study looks at the bacteria and other microbes on the eye's surface in people who develop dry eye after LASIK surgery. It aims to understand how these microbes change and may help improve future treatments for dry eye after LASIK.
Nanchang, JiangxiAges 18–45 - NCT06213038RecruitingPhase 1
Study of SKG0106 for wet age-related macular degeneration
This study tests a new medicine called SKG0106, given as an injection into the eye, for people with wet age-related macular degeneration (AMD). It aims to see if it is safe and effective in treating the leaky blood vessels that cause vision loss.
BeijingAges 50 years+ - NCT04451265Recruiting
MRI test study for suspected anterior optic nerve stroke
This study checks how well a special MRI scan (diffusion-weighted imaging) can identify a specific optic nerve problem called anterior ischemic optic neuropathy (when blood flow to the optic nerve is reduced). If you have symptoms that suggest this condition, the trial compares your MRI findings to doctors’ assessment to see if the scan helps confirm the diagnosis.
Lille, LilleAges 18 years+ - NCT05822089Recruiting
Comparing two cataract lens types in the same person
This study compares two different cataract (intraocular) lens options in each eye of the same person. It aims to see which lens gives better distance vision after standard cataract surgery.
ViennaAges 50–100 - NCT03041883Recruiting
Crosslinking to help a KPro eye resist corneal melting
This trial tests a treatment called corneal collagen crosslinking to strengthen the tissue under a KPro type I (an artificial cornea). It may help reduce the risk of corneal melting in people who need a KPro.
Montreal, QuebecAges 18–80 - NCT06881147Enrolling by invitation
Physiotherapy and Botox for Neck Dystonia
This study tests whether combining physiotherapy with Botox injections can improve neck control in people with cervical dystonia. It also looks at how 'sensory tricks' (like touching your face) help the brain control symptoms, using brain scans to understand why.
Milan, ItaliaAges Any age - NCT06293196Recruiting
Acupoint eye massage trial for healthy people
This study tests whether massaging acupoints around the eyes can improve eye health measurements. It is only for healthy people with no eye problems, recent surgeries, or caffeine before the test.
Wuhan, HubeiAges 18–80 - NCT03608280Recruiting
3D-printed implant vs own bone for rebuilding eye socket
This study compares two ways to rebuild part of the eye socket bone: a 3D-printed implant versus using the patient’s own bone. It may help show which approach works better to restore eye position and symptoms like double vision after an injury or surgery.
Pierre-BéniteAges 18–90 - NCT07640997Recruiting
Real-world study of aflibercept for age-related macular degeneration
This study follows patients receiving aflibercept 8 mg injections in the eye to treat wet age-related macular degeneration (nAMD), a condition that blurs central vision. The goal is to understand how well this treatment works and its safety in routine medical practice.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07609628Recruiting
Silicon Oil's Effect on Retinal Nerve Function
This study examines how silicon oil (a clear liquid sometimes used to repair detached retinas) affects the electrical function of the retina. Researchers will use special eye tests to measure how well the retina responds to light after treatment.
Minya, Minya GovernorateAges 18–70 - NCT03400137Recruiting
Eye pressure and vision test study in healthy and glaucoma-suspect people
This study measures how eye pressure and standard eye-function tests perform in people with normal eyes, higher eye pressure, or early signs of glaucoma. It may help researchers understand who is at risk and how best to monitor eye health before or during glaucoma.
New York, New YorkAges 18–90 - NCT07717918RecruitingPhase 1
Testing a new eye drop for capsaicin-induced eye pain
This trial tests whether a new eye drop, BL1332, can reduce eye pain caused by capsaicin (the compound that makes chili peppers spicy). If you are a healthy adult and have no eye problems, this study could help see if the drop is safe and works.
Newport Beach, CaliforniaAges 18–65 - NCT07515079RecruitingPhase 3
Testing BAT5906 vs Lucentis for diabetic vision swelling
This study compares two injectable medicines (BAT5906 and Lucentis) to treat diabetic macular edema—swelling in the back of the eye that blurs vision. Both drugs block a protein that causes abnormal blood vessel leakage, and this trial will show which works better.
Beijing, Beijing MunicipalityAges 18–80 - NCT07625358Recruiting
How Caffeine and Alcohol Affect Your Eyes
This study measures how caffeine and alcohol change the size of your pupils (the dark circles in your eyes). Researchers want to understand how these common substances affect your eye's natural responses, which could help with vision and neurological research.
SingaporeAges 30–50
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,819 recruiting ophthalmology studies from the U.S. registry right now, out of 2,909 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.