Medical genetics
Genetic & congenital clinical trials
Inherited and congenital conditions present from birth or written into the genes. We’re tracking 3,858 recruiting studies in this area right now.
By phase
- Not applicable2,771
- Phase 2283
- Phase 1235
- Phase 3216
- Phase 1/Phase 2204
- Phase 497
- Phase 2/Phase 352
Top conditions
- Sickle Cell Disease140
- Atopic Dermatitis128
- Congenital Heart Disease86
- Cystic Fibrosis78
- Down Syndrome54
- Genetic Disease42
- Duchenne Muscular Dystrophy39
- Fabry Disease38
- Hemophilia A38
- Cystic Fibrosis (CF)37
- Cardiac Amyloidosis35
- Huntington Disease32
- Lynch Syndrome32
- Heart Failure31
- Retinitis Pigmentosa31
- Bronchopulmonary Dysplasia30
- Congenital Diaphragmatic Hernia29
- Duchenne Muscular Dystrophy (DMD)27
Leading sponsors
- Assistance Publique - Hôpitaux de Paris62
- Boston Children's Hospital42
- National Institute of Allergy and Infectious Diseases (NIAID)38
- Mayo Clinic37
- Children's Hospital Medical Center, Cincinnati33
- Hospices Civils de Lyon32
- IRCCS Azienda Ospedaliero-Universitaria di Bologna32
- Riphah International University26
- Massachusetts General Hospital23
- National Cancer Institute (NCI)23
Where studies are running
- California340
- Maryland161
- Alabama132
- Massachusetts116
- New York84
- Arizona78
- Texas73
- Minnesota67
- Pennsylvania65
- Ohio57
Recruiting studies3,858 total
- NCT06876857Recruiting
UCF Cerebrospinal Fluid Biobank for Adults
This is a research biobank at the University of Central Florida that collects and stores cerebrospinal fluid samples for future studies. It is open to most adults who can give their consent.
Orlando, FloridaAges 18 years+ - NCT06877715Recruiting
Sensory and autism traits in children with Prader-Willi syndrome
This study looks at autism-like symptoms and sensory profiles in children with Prader-Willi syndrome (PWS). It aims to better understand these traits to improve care and support.
ToulouseAges 3–16 - NCT06878742RecruitingPhase 1/Phase 2
Finding the right dose of dobutamine for very preterm infants
This study is for very premature babies (born before 33 weeks) who have low blood flow from the heart. It tests different doses of dobutamine, a medicine that helps the heart pump stronger, to find the safest and most effective dose.
MadridAges Up to 3 days - NCT06878950Recruiting
Early feeding for babies with gastroschisis
This study tests whether starting feedings earlier than usual helps babies born with gastroschisis recover better. It aims to find a safer and more effective feeding plan for these newborns.
Los Angeles, CaliforniaAges birth–1 year - NCT06879431Recruiting
Sleep help before heart surgery for young children
This study tests if helping babies and toddlers with sleep problems sleep better before heart surgery can lower the risk of confusion or agitation after surgery. It is for children aged 0 to 3 years who have trouble sleeping and are scheduled for heart surgery.
BeijingAges 6–12 - NCT06880276RecruitingPhase 3
Studying QLM3003 ointment for mild or moderate eczema
This trial tests if an ointment called QLM3003 is safe and helps adults with mild to moderate atopic dermatitis (eczema). It may be a new treatment option for people whose eczema affects small areas of skin.
ShenyangAges 18–75 - NCT06880653Recruiting
Exercise dose study for arthritis pain
This study looks at how different amounts of exercise affect arthritis symptoms. If you have arthritis or a related condition, you may be asked to try a specific weekly exercise goal to see if it helps your pain and mobility.
Columbia, South CarolinaAges 18 years+ - NCT06881004Recruiting
Biliary Dilation National Cohort Study in China
This study collects health information from people in China who have biliary dilation (widening of the bile ducts). It looks at their medical history and follows some patients over time to learn more about the condition.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT06881771Recruiting
Tracking Fuchs' dystrophy progression and genetics in the UK
This study follows people with Fuchs' endothelial corneal dystrophy over time to see how the condition changes and how it relates to their genes. It aims to help doctors better predict and manage the disease.
LondonAges 18 years+ - NCT06881979Recruiting
High-tech rehab for chronic neuromuscular diseases
This study tests a high-tech rehabilitation program for people with long-term nerve and muscle conditions. It aims to help you improve your walking and daily function using advanced technology.
GenovaAges 18–80 - NCT06882148Recruiting
How long do eczema patients stay on targeted therapies?
This study looks at how long people with moderate to severe eczema stay on newer targeted medicines (biologics or pills). By reviewing medical records, researchers hope to learn which treatments work best over time and how they are used in real life.
RomeAges 18 years+ - NCT06884358Recruiting
Heart and exercise capacity in Fabry disease
This study looks at how Anderson-Fabry disease affects your heart and ability to exercise. Researchers want to understand this better by testing your heart function and how well you can do physical activity.
Brescia, BresciaAges Any age - NCT06885307Recruiting
Building a research network for children with heart conditions
This study is building a network of hospitals across China to help children with congenital heart disease. If your child was born with a heart problem and is under 18, they may be able to join and help improve care for kids like them.
Wuhan, HubeiAges Up to 18 years - NCT06887283Recruiting
Essen Amyloidosis Registry Study
This study collects information from people with suspected or confirmed amyloidosis. The goal is to learn more about the condition and improve patient care.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT06887387Recruiting
Wearable devices to monitor Long QT Syndrome
This study tests whether wearable devices can help monitor Long QT Syndrome, a heart condition. It aims to make tracking your heart easier and more convenient than clinic visits.
LondonAges 18 years+ - NCT06887777RecruitingPhase 2
Testing RAVICTI for PDH deficiency in young people
This study tests if a medicine called Glycerol Phenylbutyrate (RAVICTI) is safe and helpful for children and young adults with a specific type of PDH deficiency, a rare genetic condition affecting energy use. If you qualify, you may get a new treatment option.
Paris, FranceAges 2–25 - NCT06887907Recruiting
Studying megakaryocytes in sickle cell disease
This trial looks at the cells that help make platelets (megakaryocytes) in people with sickle cell disease. By comparing these cells when you are feeling well and during a pain crisis or chest syndrome, researchers hope to learn more about the condition and find better treatments.
Toulouse, FranceAges 18 years+ - NCT06888024Recruiting
Measuring pelvic vein blood flow with MRI
This study uses MRI scans to measure blood flow in the pelvic veins. It’s for people who either have no vein problems, or have symptoms of a compressed left iliac vein, or already have a stent in that vein. The goal is to learn more about how blood flows in these conditions.
Worcester, MassachusettsAges 18–89 - NCT06889454Recruiting
Heart and blood vessel changes in women with PCOS after treatment
This trial looks at how the heart's blood vessels and certain markers change in women with PCOS when they drink a sugary solution (OGTT). It checks these markers before treatment starts and again 6 and 12 months after, to help understand cardiovascular risk in PCOS.
ChaïdáriAges 18–45 - NCT06889480Recruiting
Deep brain stimulation for severe Tourette syndrome
This trial tests a surgical procedure using deep brain stimulation to treat severe Tourette syndrome that hasn't improved with other treatments. It may help reduce tics by targeting specific areas in the brain.
Beijing, Beijing MunicipalityAges 18–60 - NCT06891443RecruitingPhase 3
Study of Sepofarsen for LCA type 10
This study tests an investigational RNA therapy called sepofarsen for people with Leber Congenital Amaurosis (LCA) type 10, a rare inherited eye disease that causes severe vision loss from birth. The goal is to see if it can slow or improve vision loss.
San Francisco, CaliforniaAges 6 years+ - NCT06891885RecruitingPhase 1/Phase 2
Safety study of DSP-3077 for retinitis pigmentosa
This trial tests a new medicine, DSP-3077, given as a single injection into one eye to see if it is safe for people with retinitis pigmentosa. It is for adults with advanced vision loss who have no other major eye diseases.
Boston, MassachusettsAges 18 years+ - NCT06892275Recruiting
Helping high-risk women decide about breast MRI
This study tests a decision aid to help women at high risk for breast cancer decide whether to get a screening MRI. It is designed for Black and Latina women who have had a normal mammogram in the past year.
Washington D.C., District of ColumbiaAges 18–74 - NCT06892964Recruiting
Italian registry and biobank for ML patients
This study creates a national registry and biobank to collect medical information and biological samples from people with any type of ML, helping research into the condition.
RomaAges Up to 100 years
Common questions
- How many genetic & congenital clinical trials are recruiting?
- Clin2 is tracking 3,858 recruiting medical genetics studies from the U.S. registry right now, out of 5,779 we cover in this area in total.
- What does “Genetic & congenital” cover here?
- Inherited and congenital conditions present from birth or written into the genes. We group each study into genetic & congenital based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a genetic & congenital trial near me?
- Use the search to filter genetic & congenital studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.