Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07320339Recruiting
Blood pressure measurement differences in women of reproductive age
This study compares two ways of measuring blood pressure in women ages 18-40—one done exactly by guidelines and one done as usual in clinics. The goal is to see if the regular way gives different readings, which could affect diagnosis and treatment.
Hadera, IsraelAges 18–40 - NCT07320677Enrolling by invitation
Finding Heart Failure in People Taking Water Pills
This study is for people who take a type of water pill called a loop diuretic, but do not yet have a diagnosis of heart failure. The study will check a blood test to see if undiagnosed heart failure might be present.
Saint HelierAges 18 years+ - NCT07318103RecruitingPhase 2
Study of HRS-9057 for fluid retention in heart failure
This trial tests an investigational drug, HRS-9057, in people hospitalized with heart failure who still have fluid buildup despite taking standard diuretics. The goal is to see if HRS-9057 helps remove excess fluid better than current treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07324031Recruiting
Study of a new under-the-skin defibrillator (the Parasternal EV-ICD)
This study tests a new type of defibrillator that goes underneath the skin, near your breastbone, to protect against dangerous heart rhythms. It may be an option if you need an ICD but haven't had certain prior chest surgeries or devices.
Scottsdale, ArizonaAges 18 years+ - NCT07322913Recruiting
Study of Intervascular blood vessel grafts and patches
This study is collecting information from patients who have already had surgery to repair or replace blood vessels using Intervascular grafts or patches. Researchers will look at past medical records to see how well these devices work over time.
Hershey, PennsylvaniaAges 18 years+ - NCT07321899Recruiting
Study of a new tricuspid valve replacement device for severe leakage
This trial tests a new device called the Medtronic Intrepid TTVR system to replace the tricuspid valve in people with severe tricuspid regurgitation (leaky valve). It aims to see if the device can safely and effectively fix the leak and improve symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07318155RecruitingPhase 2
Study of SRSD107 for chronic heart or leg artery disease
This study tests a new medicine called SRSD107 for people with long-term blockages in heart or leg arteries. It aims to see if the drug can help prevent clots safely.
BeijingAges 18–75 - NCT07318597RecruitingPhase 2
A study of an experimental drug for pulmonary arterial hypertension
This trial tests a new medication called REGN13335 for people with pulmonary arterial hypertension (PAH). It aims to see if the drug can improve symptoms and function compared to standard care alone.
Aurora, ColoradoAges 18 years+ - NCT07324421Recruiting
Ultrasound vs. CT scan for brain blood flow imaging
This study compares a new ultrasound-based method to a standard CT scan for measuring blood flow in the brain. It is designed for people in the ICU or CCU who are already scheduled for a CT scan and could benefit from a simpler, more portable imaging option.
Montpellier, HeraultAges 18 years+ - NCT06869811Recruiting
Stroke prevention after failed blood thinners
This study is for people who had a stroke despite taking blood thinners for atrial fibrillation. It tests if adding a procedure to close the left atrial appendage (a small pouch in the heart) to your blood thinner is better than just taking the blood thinner alone to prevent another stroke.
Barcelona, BarcelonaAges 18–95 - NCT07319897RecruitingPhase 2/Phase 3
BCMA PET scan for multiple myeloma imaging
This trial tests a new type of PET scan that uses a radioactive tracer (68Ga-BCMA) to find active multiple myeloma cells in your body. It may help doctors better detect and monitor the disease.
Beijing, Beijing MunicipalityAges 18–80 - NCT07316452Recruiting
Early heart disease risk study for adults under 45
This study looks at what makes heart disease progress in younger adults (18 to 45). If you have symptoms of heart disease and have had a heart CT scan, joining this research might help doctors better predict and manage your condition.
BeijingAges 18–45 - NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT07317492Recruiting
Hemorrhoids and varicose veins study
This study looks at the connection between hemorrhoids and varicose veins. It may help researchers understand if these conditions are related and how to better treat them.
Aydin, EfelerAges 18 years+ - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT07322237RecruitingPhase 4
Study on heart function drugs for liver cirrhosis patients
This trial tests two heart medications, carvedilol and empagliflozin, to see if they improve heart function in people with cirrhosis (liver scarring). It might help those who have early signs of heart stiffness but normal pumping strength.
ChandigarhAges 18–65 - NCT07316270Recruiting
Catheter ablation for atrial fibrillation after brain bleeding
This trial studies a procedure called catheter ablation to treat atrial fibrillation (an irregular heartbeat) in people who have had a brain hemorrhage. The procedure aims to reduce stroke risk and improve heart rhythm without increasing bleeding risk.
Hefei, AnhuiAges 18 years+ - NCT07319013Recruiting
AI Ultrasound for Early Brain Bleed Detection
This trial uses an AI-assisted ultrasound to quickly detect brain bleeding in people with acute stroke. It may help speed up diagnosis and treatment.
Barcelona, CataloniaAges 18 years+ - NCT07319039Recruiting
Brain scan study of breathlessness in cancer, COPD, and heart failure
This study uses a brain scan (fMRI) to learn how the brain processes shortness of breath in people with advanced heart failure, COPD, or lung cancer. It aims to help doctors better understand and treat breathlessness.
Geneva, Canton of GenevaAges 18 years+ - NCT07324278Recruiting
Arm rehab with mirror exercises after stroke
This study tests a new kind of arm exercise that uses a mirror to help your brain recover movement after a stroke. It may help you improve arm function if you have some movement already.
Kaohsiung City, Yanchao DistrictAges 20–80 - NCT07317323Recruiting
Norwegian study on spontaneous coronary artery dissection
This trial is for people who have had a spontaneous coronary artery dissection (SCAD), a tear in a heart artery. It aims to learn more about this condition and how to treat it.
BergenAges 18 years+ - NCT07316855Recruiting
Iron-based covered stent for aortic narrowing
This trial tests a new type of stent made from iron that slowly dissolves in the body. It is designed to treat narrowing of the aorta (CoA) or narrowing that happens after CoA surgery. The goal is to see if the stent is safe and works well over one year.
Zhengzhou, HenanAges 1–60 - NCT07322133RecruitingPhase 4
Comparing two blood pressure medicines for newborns with lung hypertension
This trial compares two medicines (dopamine and norepinephrine) to see which works better for raising blood pressure in newborns who have both low blood pressure and high blood pressure in the lungs. Both medicines are given through a vein to help stabilize your baby's blood pressure.
Sacramento, CaliforniaAges Up to 4 weeks - NCT07320625RecruitingPhase 3
Montelukast for heart attack patients getting emergency artery opening
This trial tests if montelukast, a medicine used for asthma, can help people having a certain type of heart attack (anterior STEMI) recover better. You may qualify if you are having this heart attack and getting a procedure to open the artery within 12 hours.
Dalian, LiaoningAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.