Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05470335Recruiting
Nurse-led heart procedure setup for suspected heart artery disease
This study checks whether a nurse-led technique for placing a sheath (a small tube used during a heart test/procedure) works safely in people suspected of blocked heart arteries. If you qualify, your care team will guide the process and compare how it goes with standard approaches.
Roskilde, DanmarkAges 18 years+ - NCT05472337RecruitingPhase 2
Colchicine trial for better heart artery reopening after ACS
This trial tests whether colchicine (a medicine commonly used for inflammation) can improve how well clogged heart arteries reopen after a short-term heart emergency called ACS. You may be eligible if you’re hospitalized with ACS and are planned for a coronary angiogram and possible angioplasty soon.
Santiago, Santiago MetropolitanAges 18 years+ - NCT05472207Recruiting
Risk check study for heart disease patients
This study looks at how to better sort people with heart disease into different risk groups. You may be asked for information about your heart condition and related health to help guide future care.
Innsbruck, TyrolAges 18 years+ - NCT05473637Recruiting
Study causes of small vessel brain disease in stroke and memory issues
This trial looks at people who may have “small vessel” problems in the brain, which can cause stroke, memory trouble, walking changes, movement symptoms, or headaches. It may help researchers better understand the genetic and non-genetic causes, which could improve future diagnosis and treatment.
TaipeiAges 18 years+ - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05473871Recruiting
Help churches deliver low-exercise physical activity programs
This trial tests a program to help churches support people who currently get little exercise to become more active. You may be invited to join activities through your church over the next 18 months.
San Diego, CaliforniaAges 18–65 - NCT05474092Recruiting
Follow-up study for an artificial heart you may receive
This study follows people who are planning to receive the Aeson TAH (total artificial heart) under normal care. It mainly checks outcomes after the device is placed, helping doctors monitor safety and performance over time.
DresdenAges 18 years+ - NCT05476627Recruiting
Study risk factors for kidney disease from metabolic conditions
This study looks at risk factors and body “omics” information (like blood/tissue patterns) to better understand chronic kidney disease caused by metabolic diseases. It may help researchers find better ways to predict or manage kidney problems in people with these conditions.
Beijing, Beijing MunicipalityAges 18–80 - NCT05476913Recruiting
Preventing blood clots after stroke with a leg device
This study checks whether using a special device on the legs can help prevent dangerous blood clots after an acute stroke. You may be eligible if you recently had a stroke and you’re not able to get up and walk to the toilet without help.
Bury St Edmunds, SuffolkAges 18 years+ - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT05477680Recruiting
Measuring brain shift during surgery using navigation
This study tests whether a special brain-navigation method can better measure how the brain moves during surgery for certain brain conditions. If it works, it may help surgeons avoid mistakes caused by brain shifting while you are under anesthesia.
MoscowAges 18–100 - NCT05479305Recruiting
Stent placement for thoracic aorta problems in urgent high-risk patients
This trial studies a new type of stent graft placed in the chest aorta (from the aortic arch into the descending part) to treat aneurysms or dissections in people who are too high-risk for open surgery. It may help by offering a faster, less invasive repair when waiting for a custom stent would be unsafe.
BrestAges 18 years+ - NCT05479006Recruiting
tDCS for arm weakness after stroke
This trial tests whether a targeted, noninvasive brain stimulation (tDCS) can improve arm weakness and movement after stroke. It may help people who have significant trouble moving one arm on the side affected by stroke.
Urbana, IllinoisAges 18–90 - NCT05479461Recruiting
Phone-based blood pressure care vs usual care
This trial tests whether a technology-enabled program (using a smartphone) helps lower blood pressure better than standard care. It may help you manage high blood pressure with guided treatment changes.
Palo Alto, CaliforniaAges 30–90 - NCT05479448Recruiting
Tracking what predicts response in new PMR or GCA
This study looks at people newly diagnosed with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) and uses their health and treatment information to learn what predicts how well treatment works. It may help your care in the future by improving which patients respond best and how.
BaselAges 18 years+ - NCT05479669Recruiting
Testing detailed heart scans in people with heart failure symptoms
This study looks at whether doing very detailed heart testing helps understand and guide care for people with heart failure with preserved pumping strength. You may be eligible if you’re an adult with specific symptom levels, recent heart-failure-related visits, and matching scan and blood test results.
GroningenAges 18 years+ - NCT05480319Recruiting
Testing a cardiac arrest response system in the emergency room
This trial checks whether a new emergency-room system helps respond faster and more consistently when someone has a cardiac arrest. If you are eligible, you may be included while you are treated in the emergency department.
TaipeiAges 20 years+ - NCT05482269Recruiting
Using CT scans to predict outcomes after lung blood clots
This trial uses an artificial intelligence (AI) system to read CT scan images of the lungs and predict outcomes after a pulmonary embolism (a blood clot in the lung). It may help doctors identify who is at higher risk, so treatment decisions can be faster and more accurate.
Shenyang, LiaoningAges 18 years+ - NCT05482945RecruitingPhase 2
Argon treatment for certain out-of-hospital cardiac arrest patients
This Phase 2 trial tests whether breathing “argon” through a breathing device, started soon after successful CPR, can improve recovery in adults who had a witnessed, shockable cardiac arrest. It is for ICU patients who were unconscious right after return of heartbeat and meet specific timing and oxygen level requirements.
Genova, GEAges 18 years+ - NCT05484115Recruiting
EVAR versus a new method for certain aortic aneurysms
This study compares two ways to treat an abdominal aortic aneurysm (a bulge in the lower part of the aorta). It looks at whether the newer approach works as well as standard EVAR in people whose aneurysm has a wider neck that may be harder to treat.
Washington, ArkansasAges 18 years+ - NCT05484245Recruiting
Ultrasound-guided surgery for certain brain mass lesions
This trial looks at using real-time ultrasound to help surgeons remove or treat certain brain growths and bleeding areas. It may help by making the procedure more precise for newly diagnosed cases in the upper part of the brain.
MoscowAges 18–100 - NCT05485376Recruiting
Pulmonary artery catheter use in cardiogenic shock patients
This trial studies whether using a special pressure-monitoring tube in the heart’s main artery (a pulmonary artery catheter) helps people who are in cardiogenic shock from weak heart pumping. If you qualify, the goal is to improve how doctors monitor and treat this dangerous, fast-moving condition.
Boston, MassachusettsAges 18–90 - NCT05486000Recruiting
Testing a device to help chronic left heart failure
This trial studies a small implant (an “atrial shunt” device) to improve symptoms and heart function in people with chronic left heart failure that stays active despite standard medicines. It focuses on whether the implant is safe and can help you feel better and possibly breathe easier.
Nantong, JiangsuAges 18 years+ - NCT05486884Recruiting
Blood pressure goal after out-of-hospital cardiac arrest
This study looks at whether targeting a specific blood pressure after a cardiac arrest can improve outcomes. It is mainly for people who are in intensive care and need a breathing machine because they are in a deep coma.
BrestAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.