Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07333079Recruiting
Rehabilitation with biofeedback for stroke recovery
This study tests if adding biofeedback to standard rehabilitation improves hand and arm function after a stroke. Biofeedback uses sensors to show you how your muscles are working, helping you regain movement.
RzeszówAges 45–80 - NCT02662751Recruiting
Low-dose whole-body scan after stroke or TIA
This study looks at whether a low-dose whole-body imaging scan soon after a stroke or TIA (sometimes called a “mini-stroke”) can help doctors evaluate you. It also includes long follow-up to see how patients do over time.
MontpellierAges 18–89 - NCT04933136Recruiting
Check how to stop bleeding after wrist artery catheter
This study tests two ways to control bleeding after a heart/blood-vessel procedure done through the wrist (or elbow) artery. It may help make the procedure safer and improve how well the artery is managed during healing.
Chicoutimi, QuebecAges 18 years+ - NCT03559569Recruiting
Study blood changes in people with circulatory shock
This study looks at how blood vessel and white blood cell aging changes during circulatory shock. Your participation may help doctors better understand what’s happening in the body during shock.
StrasbourgAges 18 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT05426408Recruiting
Test study for heart attacks without blocked arteries
This study looks at people who may have MINOCA (heart attack symptoms with no major artery blockage) or takotsubo syndrome (a temporary stress-related heart condition). The goal is to better understand these causes and how they should be diagnosed and treated.
StockholmAges 35–79 - NCT06844227Recruiting
Virtual Visit to Manage Blood Thinners Around Surgery
This study looks at whether a virtual visit can safely manage your blood thinners around the time of a planned surgery. You would stop your medication before the procedure and restart it after, but all instructions and check-ins happen remotely (phone or video).
Evanston, IllinoisAges 18–100 - NCT06666361Recruiting
Blood pressure support for older adults in rural areas
This trial tests whether text messages or mobile health tools can help middle-aged and older adults with high blood pressure manage their condition better. It may be a good fit if you have had high blood pressure for at least a year, take medication for it, and are comfortable using a smartphone.
Tainan, TaiwanAges 45 years+ - NCT06866769Recruiting
Comparing imaging tests for aneurysm follow-up after EVAR
This study compares two imaging methods (CTA and CEUS) plus blood biomarkers to see which works best for monitoring your aneurysm after EVAR repair.
Valencia, ValenciaAges 18 years+ - NCT06866912Recruiting
Observational study of amyloidosis and TTR gene carriers
This study is observing people with amyloidosis or those who carry a specific gene mutation (transthyretin) to learn more about the condition. It does not test any new treatment, but may help researchers understand how the disease affects people.
BolognaAges 18–99 - NCT06866535Recruiting
Vascular infection study for patients 18 and older
This trial is studying patients with infections in blood vessels, whether natural or from a graft, to better understand and treat them.
BordeauxAges 18 years+ - NCT05347069RecruitingPhase 4
Aspirin study for people with stable heart artery disease
This trial tests whether daily aspirin is safe and effective for people who have stable (chronic) coronary artery disease but cannot have procedures to open blocked arteries. It may help reduce future heart problems, while also checking for side effects and risks from aspirin.
KyotoAges 20 years+ - NCT03186391Recruiting
Exercise testing for leg artery disease symptoms
This study tests how well people with peripheral artery disease can use a treadmill for exercise testing. It may help doctors better understand exercise limits and guide safer care.
RennesAges 1.5 years+ - NCT05389878Recruiting
Stroke patient registry for people within 6 months of stroke
This trial sets up a registry (a secure database) to better track and understand adults who have had an ischemic or hemorrhagic stroke within the last 6 months. Being listed may help researchers learn what care works best for different types and stages of stroke.
FlorenceAges 18 years+ - NCT05166343RecruitingPhase 2/Phase 3
Testing a shot of epinephrine during out-of-hospital CPR
This trial studies whether giving a medicine shot (epinephrine) into the muscle helps children who have a cardiac arrest outside the hospital. It’s meant for emergency situations where CPR is started right away by trained responders.
London, OntarioAges 1 day–17 years - NCT06156813Recruiting
Turkish lower limb movement log for stroke patients
This study aims to adapt a questionnaire that measures how well stroke survivors can use their legs in daily life. It may help doctors better understand your recovery and guide your rehabilitation.
GaziantepAges 18–80 - NCT06337227Recruiting
Studying sirtuins as biomarkers for artery or heart valve disease
This study tests whether proteins called sirtuins can be used as biomarkers (biological clues) to better understand patients with hardened arteries (atherosclerosis) or calcified heart valve disease (calcific aortic stenosis), especially if you also have diabetes. It may help doctors develop better ways to diagnose or monitor these conditions.
NaplesAges 18 years+ - NCT06443580Recruiting
A mind-body program for pulmonary hypertension
This trial tests a program that helps you notice and manage body signals (like breathlessness) to improve how you feel day-to-day. It is designed for people with any type of pulmonary hypertension.
Glasgow, ClydebankAges 18 years+ - NCT06610994Recruiting
Vibration therapy for stroke recovery
This study tests if a short, local vibration treatment can help stroke patients with leg spasticity (tightness in the calf muscle) improve walking. If you have had a stroke and have mild to moderate spasticity in your lower leg, you may be able to join.
KirikkaleAges 45–75 - NCT06765265RecruitingPhase 4
Comparing two statins' effect on vitamin D after heart attack
This study compares two common statins (atorvastatin and rosuvastatin) to see how they affect vitamin D levels in people who have recently had a heart attack or unstable angina. It may help doctors choose the best statin for your heart and vitamin D health.
Lahore, Punjab ProvinceAges 18–65 - NCT06863350Recruiting
Closing a heart hole to treat drug-resistant epilepsy
This trial tests if closing a small hole in the heart (called a PFO) can reduce seizures in people whose epilepsy isn't controlled by medication. It might offer a new treatment option for those who have both drug-resistant epilepsy and this heart condition.
Chengdu, SichuanAges 18–60 - NCT06847568RecruitingPhase 3
Adrenaline during heart artery procedure to prevent poor blood flow
This study tests whether giving adrenaline (a medicine that helps blood vessels relax) directly into the heart artery during a procedure to open a blocked artery can prevent a complication called 'no reflow' (where blood still doesn't flow well after the blockage is cleared). It is for people having a specific type of heart attack (STEMI) and being treated within 12 hours.
CairoAges 18 years+ - NCT07320703Recruiting
Diagnosing breathlessness in primary care
This project tests whether a tool called "Breathlessness Diagnostics in a Box" helps doctors find the cause of breathlessness more quickly. If you have unexplained or ongoing trouble breathing, this study may help improve your care.
GroningenAges 18 years+ - NCT07323667Enrolling by invitation
Study of a first responder system for cardiac arrest in Zug
This trial is studying a new system where trained volunteers respond quickly to help people whose heart stops outside of a hospital in Zug, Switzerland. The goal is to see if this system improves survival and recovery.
Zug, Canton of ZugAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.