Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06162247Recruiting
Registry study for heart patients in intensive care
This study tracks patients with sudden heart problems admitted to a special heart intensive care unit. It helps doctors learn more about these conditions to improve future care.
NaplesAges 18 years+ - NCT06162780Recruiting
Clip repair for severe mitral valve leak
This trial tests a clip-based procedure (TEER) to fix a severe leak in the mitral valve for people who have symptoms or heart changes but are at low to medium risk for surgery. The goal is to see if this less invasive option works well and is safe.
Guangzhou, GuangdongAges 18 years+ - NCT06163547Recruiting
Brain artery treatment for chronic subdural hematoma
This study tests a new way to treat chronic subdural hematomas (a type of bleeding on the brain) by using a very thin tube to seal off a small artery inside the head. This may help the blood clot shrink without needing a traditional surgery.
GenevaAges 18–100 - NCT06164262Recruiting
Dementia risk study for people with small vessel disease
This study tracks people ages 30 to 60 who have signs of small vessel disease on brain MRI. It aims to understand the risk of dementia over the next 10 years, so you can get early monitoring and care.
Hangzhou, ZhejiangAges 30–60 - NCT06164457Recruiting
Using patient reports to improve heart disease care
This trial tests whether asking patients to report their own symptoms and quality of life during routine heart check-ups helps doctors better care for people with coronary artery disease. You may be eligible if you are 40 or older, have known or suspected heart artery problems, and have an upcoming visit with a cardiologist.
Calgary, AlbertaAges 40 years+ - NCT06164808Recruiting
Comparing a wearable heart monitor to a standard Holter monitor
This study compares a new wearable heart monitor (HeartWatch) that you wear on your left bicep to the standard Holter monitor. It aims to see if the HeartWatch is as good at recording your heart's rhythm over 24-48 hours, so you might have a more comfortable option for heart monitoring.
Calgary, AlbertaAges 22 years+ - NCT06165510Recruiting
Convergent ablation and left atrial appendage isolation for persistent AF
This trial tests a two-step procedure for persistent atrial fibrillation that combines a heart ablation with isolation of a small heart pouch. It aims to see if this approach is more effective than standard care.
LondonAges 18–80 - NCT06166277Recruiting
Ablation for fainting and slow heartbeat registry
This study tests a procedure called cardioneuroablation for people whose fainting or very slow heartbeat doesn't improve with other treatments. If you are under 60, have no other major heart conditions, and have not had ablation before, it might be an option to reduce or stop your fainting spells.
Chicago, IllinoisAges 18–60 - NCT06166329Recruiting
Chair lift test for pulmonary embolism prognosis
This study checks if a simple chair lift test can help predict recovery in patients with a blood clot in the lung (pulmonary embolism) who are not critically ill. It aims to find out if this test can help doctors decide on the best follow-up care.
RouenAges 18 years+ - NCT06166537Recruiting
Compression Stockings for Blood Clot Prevention After Surgery
This study tests if wearing compression stockings after surgery can help prevent blood clots in people who already need to take blood thinners for an extended period. The stockings are used in addition to the blood thinners.
BristolAges 18 years+ - NCT06168123Recruiting
Future care for aortic stenosis
This research study is a registry that collects information about people with aortic stenosis, a condition where a heart valve becomes narrow. The goal is to learn more about how this condition is managed and to improve future care.
NieuwegeinAges 18–110 - NCT06168370Recruiting
Personalized blood thinners after TAVI vs. standard care
This trial tests whether a personalized plan for blood thinners after TAVI can reduce the risk of stroke or bleeding better than the current standard of one daily blood thinner. If you've had a successful TAVI and don't need specific other blood thinners, you might be able to join.
NieuwegeinAges 18–110 - NCT06168422Recruiting
Stent study for elderly with severe artery calcium
This study tests a way to open severely hardened arteries in people aged 60 and older using a special tube (stent). It may help if you have complex blockages and are a candidate for angioplasty.
Zhengzhou, HenanAges 60 years+ - NCT06169241RecruitingEarly Phase 1
Nitrate supplement for resistant hypertension
This trial tests whether a natural nitrate supplement (like beetroot juice) can help lower blood pressure and improve blood vessel function in people with resistant hypertension. If you have resistant hypertension and your medications have been stable for at least 30 days, you may be eligible.
Rio de JaneiroAges 18–75 - NCT06170541Recruiting
Comparing heart artery scans for coronary disease
This study tests whether a newer CT scan method can better detect coronary heart disease. You may qualify if your doctor referred you for a heart CT scan.
Baltimore, MarylandAges 21–85 - NCT06170944Recruiting
Stroke recovery: Testing blood flow boost therapy
This study tests a simple, non-invasive treatment called remote ischemic preconditioning. It uses a blood pressure cuff on your arm to temporarily restrict blood flow, which may help improve blood flow to the brain after a stroke. The goal is to see if this can strengthen the brain's backup blood vessels and aid recovery.
ShenyangAges 40 years+ - NCT06170736Recruiting
Radiofrequency vs. doppler-guided surgery for hemorrhoids
This study compares two minimally invasive procedures for treating symptomatic grade 2 or 3 hemorrhoids: radiofrequency ablation and doppler-guided hemorrhoidal artery ligation. The goal is to see which one works better and is safer.
AmiensAges 18–80 - NCT06172101Recruiting
Fat flap surgery for recurrent thoracic outlet syndrome
This trial tests whether using a free fat flap during repeat surgery for neurogenic thoracic outlet syndrome can improve outcomes. It may help patients who have had symptoms come back after their first surgery.
NantesAges 18 years+ - NCT06173115Recruiting
One vs two stitch devices for TAVR valve replacement
This study compares using one versus two special stitch devices to close the artery after a TAVR procedure. It helps doctors learn which way works better to prevent bleeding or complications.
Bengbu, AnhuiAges 65 years+ - NCT06174103Recruiting
BiVACOR total artificial heart early feasibility study
This study tests a new total artificial heart called BiVACOR for people with severe heart failure that cannot be helped by standard pumps. It is designed to keep you alive while you wait for a heart transplant.
Phoenix, ArizonaAges 18–70 - NCT06174220RecruitingPhase 2
Tideglusib for genetic arrhythmogenic cardiomyopathy
This trial tests a medication called tideglusib to see if it can reduce extra heartbeats in people with a genetic form of arrhythmogenic cardiomyopathy. It may help stabilize the heart's rhythm and slow disease progression.
Calgary, AlbertaAges 18 years+ - NCT06174597RecruitingEarly Phase 1
Stem cells for critical limb ischemia treatment
This trial tests whether stem cells from umbilical cord arteries can help people with severe leg pain or ulcers due to blocked arteries. It is for those who cannot have surgery or other procedures.
Nanjing, JiangsuAges 18–80 - NCT06174506Recruiting
Predicting atrial fibrillation in pacemaker patients
This study is looking at whether two blood tests (hs Troponin I and NT-proBNP) can help predict if people with a permanent pacemaker will develop atrial fibrillation, a common heart rhythm problem. If you need a pacemaker, you may be able to join and help researchers learn more.
Ho Chi Minh City, None SelectedAges 18 years+ - NCT06174753RecruitingPhase 3
Dapagliflozin for large heart attacks (STEMI)
This trial tests whether a diabetes drug called dapagliflozin can help people recover from a major heart attack (STEMI). You may qualify if you had a large heart attack within the last 12 hours and have not had a heart attack before.
Ottawa, OntarioAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.