Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06150950Recruiting
Exercise rehab for Fontan failure
This trial tests if a supervised exercise program (cardiac rehabilitation) can help people who have had a Fontan procedure and are now experiencing heart failure symptoms. It aims to improve your strength, stamina, and overall well-being.
Stanford, CaliforniaAges 18 years+ - NCT06151730Recruiting
Managing blood pressure and heart risks during BTKi treatment
This study looks at how well blood pressure is managed and whether heart problems can be prevented in people with certain blood cancers who are taking a type of targeted therapy called a BTKi. It aims to help you stay healthier during treatment.
Rochester, MinnesotaAges Any age - NCT06152406Recruiting
Ablate and Pace HIS for atrial fibrillation and heart failure
This study tests a new approach called 'Ablate and Pace HIS' for people with atrial fibrillation and heart failure who haven't improved with other treatments. It combines a heart ablation procedure with a special type of pacing to help your heart pump more efficiently and reduce symptoms.
Leicester, LeicestershireAges 18–100 - NCT06152328Recruiting
Virtual reality mirror therapy for arm recovery after stroke
This study tests whether virtual reality mirror therapy can help people recover arm movement after a stroke. It is for people who had an ischemic stroke a few months ago and still have some arm weakness.
Bolu, MerkezAges 40–80 - NCT06152614Recruiting
Healthy diet and exercise for Black adults with high blood pressure
This study tests a combined eating and exercise program for Black adults with high blood pressure. The MIND-style diet and aerobic training may help lower your blood pressure over time.
Indianapolis, IndianaAges 35–75 - NCT06153147Recruiting
Kidney & blood pressure in childhood cancer survivors
This study looks at kidney health and blood pressure in childhood cancer survivors. If you finished high-risk cancer therapy about 3 years ago, researchers want to see how your kidneys and blood pressure are doing now.
Toronto, OntarioAges Up to 19 years - NCT06153251RecruitingPhase 1
Study of BMS-986453 for Relapsed or Refractory Multiple Myeloma
This study tests a new drug, BMS-986453, for people with multiple myeloma that has come back or stopped responding to previous treatments. The goal is to see if it is safe and works against the cancer.
Birmingham, AlabamaAges 18 years+ - NCT06153407Recruiting
Genetic test for early valve disease in bicuspid aortic valve
This study looks at how genes may affect the risk of calcium buildup in the aortic valve in people with a bicuspid aortic valve. By joining, you help researchers find better ways to predict and manage this heart condition.
SeoulAges 19–80 - NCT06153589Recruiting
Music therapy for leg ulcer pain relief
This trial tests whether listening to music during wound cleaning can reduce pain for people with leg ulcers caused by vein or artery problems. It aims to make the procedure more comfortable.
Fort-de-FranceAges 18 years+ - NCT06154044RecruitingPhase 2
Cell therapy for heart recovery with LVAD support
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
LjubljanaAges 18–65 - NCT06155032Recruiting
Clot Removal for Worsening Mild Stroke
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Fuyang, AnhuiAges 18 years+ - NCT06154915Recruiting
Immune cells in diabetic foot ulcers
This study looks at immune cells in chronic foot ulcers caused by diabetes. It may help researchers understand how these ulcers heal, which could lead to better treatments.
Huddinge, Stockholm CountyAges 18–98 - NCT06156813Recruiting
Turkish lower limb movement log for stroke patients
This study aims to adapt a questionnaire that measures how well stroke survivors can use their legs in daily life. It may help doctors better understand your recovery and guide your rehabilitation.
GaziantepAges 18–80 - NCT06156670Recruiting
A study of closing a PFO to prevent strokes
This trial looks at the safety and results of closing a PFO (a small hole in the heart) in people who have had a stroke or embolism with no other clear cause. If you qualify, doctors will close your PFO using a small tube inserted through a blood vessel and then follow your health over time.
MoscowAges 18–70 - NCT06157437Recruiting
Focal pulse ablation for atrial flutter
This study tests a new device that uses focused pulses of energy to treat a common type of fast heartbeat called typical atrial flutter. It aims to see if this approach is safe and effective for people who have had at least one episode in the past 6 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06157502RecruitingPhase 3
Shuxuening with clot-busting treatment for ischemic stroke
This trial tests if adding the herbal injection Shuxuening to standard clot-busting treatment improves recovery for people having an ischemic stroke. It is for adults within 6 hours of symptom onset who are already receiving a clot-dissolving medication.
Beijing, Beijing MunicipalityAges 18–100 - NCT06158087Recruiting
Stent-assisted coiling for wide-neck brain aneurysms
This trial tests a new stent-assisted coiling procedure for people with wide-neck brain aneurysms. The goal is to see if the treatment is safe and effective, and you might be a good candidate if you haven't had previous aneurysm treatment and are in generally good health.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06158269RecruitingPhase 2
DVRd treatment for newly diagnosed double-hit myeloma
This trial tests a combination of four drugs (daratumumab, bortezomib, lenalidomide, and dexamethasone) for people newly diagnosed with a high-risk form of multiple myeloma called double-hit myeloma. It aims to see if this drug combo can improve outcomes for those with two or more high-risk genetic changes.
TianjinAges 18–70 - NCT06158412RecruitingPhase 2
ATRA plus KPD for relapsed or refractory multiple myeloma
This trial tests a combination of all-trans retinoic acid (a form of vitamin A) with a chemotherapy regimen called KPD for patients whose multiple myeloma has come back or is not responding to standard treatments. The goal is to see if this combination can help control the disease.
Xiamen, FujianAges 18 years+ - NCT06158750Recruiting
Flow diverter for brain aneurysms: safety and effectiveness study
This trial tests a device called a flow modulation device to treat certain brain aneurysms. It aims to see if the device is safe and works well for people with aneurysms that have not burst.
BeijingAges 18–80 - NCT06158698RecruitingPhase 3
Colchicine for heart inflammation with arrhythmias
This trial tests whether the drug colchicine can help people with heart muscle inflammation (myocarditis) that also causes abnormal heart rhythms, a weak heart pump, or high stress markers. Colchicine is an anti-inflammatory medicine that might reduce heart damage and improve symptoms.
Naples, CampaniaAges 18 years+ - NCT06159764Recruiting
Registry of nerve-targeting heart treatment for fainting
This registry tracks people who receive a heart procedure called cardioneuroablation to stop severe fainting spells. The procedure targets nerve signals that cause the heart to pause, and researchers want to learn how well it works in real-world patients.
BronAges 18–100 - NCT06160921Recruiting
Predicting high blood pressure outcomes
This study is building a tool to predict how high blood pressure (primary hypertension) may progress over time. Researchers at Xinjiang Medical University will use health information from patients to create this model, which could help doctors tailor treatment.
Ürümqi, XinjiangAges Any age - NCT06161649Recruiting
Mobile education for heart failure patients
This trial tests a mobile education system designed to help people with heart failure learn more about their condition, build confidence in managing it, and improve their quality of life. You'll use a smartphone app to access helpful information and support.
KeelungAges 20 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.