Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06187311RecruitingPhase 4
Rivaroxaban for atrial fibrillation patients
This trial tests two doses of rivaroxaban (15mg and 20mg) to see how well they prevent strokes in people with non-valvular atrial fibrillation, a type of irregular heartbeat not caused by a heart valve problem. It may be an option if you need blood thinners to lower your stroke risk.
SeoulAges 19–99 - NCT06187467Recruiting
Understanding balance and walking after a first stroke
This study tracks how balance and walking change over time after a first stroke, using simple tests and wearable sensors. It may help find better ways to help you recover your ability to walk safely.
Singapore, SingaporeAges 21–85 - NCT06187441RecruitingPhase 3
Testing a treatment break in multiple myeloma
This trial is for people with multiple myeloma who have already completed 12 cycles of a standard treatment (daratumumab, lenalidomide, and dexamethasone) and are doing well. It tests whether taking a break from treatment is safe and effective, instead of continuing without a break.
's-HertogenboschAges 18 years+ - NCT06189092Recruiting
Electrosclerotherapy for low-flow venous malformations
This study is testing a treatment called electrosclerotherapy for low-flow venous malformations. It uses a medicine (bleomycin) injected into the abnormal blood vessels to shrink them. The goal is to see how well it works and how safe it is.
Bologna, Emilia-RomagnaAges 16 years+ - NCT06189950Recruiting
Testing a new stent for wide-necked brain aneurysms
This trial is testing a new stent (a small mesh tube) designed to treat wide-necked brain aneurysms. If you have this type of aneurysm, the stent helps hold coils in place to block blood flow and prevent rupture.
Zhengzhou, HenanAges 18–80 - NCT06189976Recruiting
Can a quick heart pacing test after TAVI predict pacemaker need?
This study checks if a short, controlled heart pacing procedure right after your TAVI (a valve replacement) can tell doctors whether you might need a permanent pacemaker later. It aims to help avoid unnecessary pacemakers.
BrusselsAges 18 years+ - NCT06190210Recruiting
Brain blood flow study in infants with heart defects
This study measures how well blood flows to the brain in infants with serious heart defects. The results may help doctors understand and protect brain development before and after heart surgery.
Leuven, Vlaams-BrabantAges Up to 6 months - NCT06190834Recruiting
HDL subtypes and heart disease outlook study
This study looks at how different subtypes of HDL (the 'good' cholesterol) relate to the outlook for people with coronary artery disease. If you have heart artery blockages and your HDL subtypes have been checked, this trial might help understand your prognosis better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06192251Recruiting
Lifestyle medicine program for chronic conditions
This trial tests a complete lifestyle medicine program to help people with conditions like prediabetes, diabetes, high blood pressure, heart disease, high cholesterol, or being overweight. The program aims to improve your overall health through diet, exercise, and other lifestyle changes.
Parry Sound, OntarioAges 18 years+ - NCT06192953Recruiting
Early movement therapy after stroke
This trial tests a type of therapy that uses gentle movements and pressure to help your brain and body recover after a stroke. It's for people who recently had a stroke and have weakness on one side, and you will be asked to do special exercises guided by a therapist.
NiceAges 18–100 - NCT06193928Recruiting
Long-term safety study of Livmarli in ALGS or PFIC
This study is following patients who are already taking Livmarli (maralixibat) for Alagille syndrome or PFIC to see how safe and effective it is over the long term.
Los Angeles, CaliforniaAges Any age - NCT06194409Recruiting
Heart infection in drug users vs. non-users
This study looks at how infective endocarditis (a serious heart infection) differs between people who use intravenous drugs and those who do not. It aims to understand patterns, symptoms, and outcomes to help improve care.
AsyutAges 18 years+ - NCT06194617Recruiting
Rivaroxaban for older Chinese patients with blood clots in lungs
This trial tests whether a blood thinner called rivaroxaban (a pill) works well for older Chinese patients who have had a blood clot in their lungs and are now on long-term treatment. It aims to see if it's safe and effective for this group.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06194591Recruiting
Ultrasound treatment for high blood pressure with kidney disease
This trial tests a new ultrasound treatment on the kidney arteries to see if it can safely lower blood pressure in people with high blood pressure and chronic kidney disease. It may help avoid more invasive procedures.
Lausanne, Canton of VaudAges 18–82 - NCT06194669Recruiting
VHL disease and kidney tumor risk study
This study looks at how early changes in kidney cells can lead to tumors in people with VHL disease. It may help understand why some people develop kidney cancer and how to prevent it.
MilanAges 18 years+ - NCT06194968Recruiting
Stroke treatment with urokinase in real-world settings
This study looks at how well the clot-busting drug urokinase works for treating acute ischemic stroke in everyday medical practice. It may help if you have had a stroke and are eligible for clot-dissolving medication.
Lanzhou, GansuAges 18 years+ - NCT06195267Recruiting
Sivelestat for lung protection during emergency aortic surgery
This study tests whether a drug called sivelestat can protect your lungs and other organs during emergency surgery for a very serious aortic tear. If you qualify, you would receive the drug or a placebo right before and after surgery.
BeijingAges 18–90 - NCT06195345Recruiting
Brain oxygen study for children having an MRI
This study looks at oxygen levels in the brains of children and young adults (birth to 18 years) during a standard MRI. The goal is to learn more about how the brain works, and it only adds a few minutes to your child's regular MRI scan.
Los Angeles, CaliforniaAges 1 minute–18 years - NCT06195501Recruiting
Swallowing after heart ultrasound in acute stroke: follow-up study
This study follows stroke patients who get a TEE (a heart ultrasound through the mouth) to see how often swallowing problems occur after the procedure. If you qualify, researchers will check your swallowing to better understand and manage any risks.
Giessen, HesseAges 18 years+ - NCT06195540RecruitingPhase 3
Rivaroxaban versus LMWH for leg injuries needing a cast
This trial compares two blood thinners (rivaroxaban pills versus LMWH shots) to see which is better at preventing blood clots in people with leg injuries that require a cast or brace. If you qualify, you can receive one of these treatments while your leg heals.
AgenAges 18 years+ - NCT06196047RecruitingPhase 3
Ticagrelor vs cilostazol for minor stroke or TIA
This study compares two blood thinner medicines, ticagrelor and cilostazol, to see which is better at preventing another stroke in people who have just had a minor stroke or TIA (a mini-stroke). It is for people who started treatment within 24 hours of their symptoms.
Kafr ash ShaykhAges 18–75 - NCT06196255RecruitingPhase 1/Phase 2
CAR-T cell therapy for resistant or relapsed multiple myeloma
This trial tests a new CAR-T cell therapy that targets FcRL5 on myeloma cells. It's for people whose myeloma has come back or stopped responding to other treatments, including stem cell transplant.
Xuzhou, JiangsuAges 18–70 - NCT06196229Recruiting
Virtual reality video therapy for arm recovery after stroke
This study tests whether watching virtual reality videos of arm movements can help improve arm function after a stroke. It may be a good fit if you have some movement in your affected arm and can follow instructions.
Lahore, Punjab ProvinceAges 40–60 - NCT06197048Recruiting
Nutrition counseling for schizophrenia or bipolar disorder
This study tests whether nutritional counseling can improve body measurements and health markers in people with schizophrenia, psychosis, or bipolar disorder. It may help you manage weight and overall health.
Drammen, AkershusAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.