Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06197503Recruiting
Comparing two types of heart pacing after TAVI
This trial compares two ways to pace the heart after a TAVI procedure for people who need a pacemaker. It aims to find which pacing method works better for preserving heart function.
BarcelonaAges 18 years+ - NCT06199401Recruiting
Testing a new surgery for type A aortic tear
This trial tests a new surgical method (XJ-Procedure) for people with an acute tear in the upper part of the main artery from the heart (type A aortic dissection). It may offer a safer option for those needing 'Sun's procedure' surgery.
Xi'an, ShaanxiAges 18–70 - NCT06200753Recruiting
Late stroke treatment study for large vessel blockages
This study looks at patients who had an ischemic stroke (a type of stroke caused by a blood clot) more than 24 hours ago and have a blockage in a large brain artery. It compares outcomes for those who get a procedure to remove the clot versus those who get only medical treatment.
Tianjin, Tianjin MunicipalityAges Any age - NCT06200311Recruiting
Atrial fibrillation ablation to prevent heart damage in women and men
This trial tests whether a procedure called AF ablation (which treats irregular heartbeats) can stop further damage to the heart muscle caused by atrial fibrillation. It may help people with both atrial fibrillation and early signs of heart muscle weakening.
GroningenAges 65–80 - NCT06201598Recruiting
Treatment for brain aneurysms with flow-diverter stents
This study is testing if a type of stent called a flow-diverter is safe and effective for treating brain aneurysms. It may help patients who have an aneurysm that was found by chance, is causing symptoms, or has already ruptured.
A CoruñaAges 18 years+ - NCT06202638Recruiting
Predicting low blood pressure during lung surgery
This study tests a new tool that warns doctors when your blood pressure might drop during lung surgery. If it works well, it could help prevent complications and keep you safer during the operation.
AthensAges 18 years+ - NCT06202755RecruitingPhase 3
Comparing ticagrelor and cilostazol for large-vessel stroke
This trial compares two antiplatelet drugs (ticagrelor and cilostazol) to see which is better at preventing another stroke in people who have had a large-vessel ischemic stroke. Both drugs help keep blood clots from forming, and the study aims to find the safest and most effective option for patients who cannot receive clot-busting medication.
Kafr ash ShaykhAges 18–75 - NCT06202846Recruiting
Looking for Y chromosome in Turner syndrome blood
This study looks for a tiny piece of the Y chromosome (a sex chromosome normally found in males) in a blood sample. It may help doctors better understand Turner syndrome and find hidden Y chromosome material that could affect health.
LyonAges 2–74 - NCT06203847Recruiting
Prehospital drug combo for cardiac arrest
This trial tests whether a combination of three medications (epinephrine, vasopressin, and a steroid) given by paramedics before arriving at the hospital can improve survival for adults who have a cardiac arrest outside of a hospital. It is only for patients who are treated by specially trained paramedics and meet specific medical criteria.
TaipeiAges 18 years+ - NCT06203860Recruiting
Heart-focused clinic for diabetes and heart disease
This study is testing whether a special heart-focused clinic can help people with type 2 diabetes who also have heart or blood vessel problems. If you have both diabetes and a heart condition like prior heart attack, stroke, heart failure, or hard-to-control high blood pressure, this program may support your health.
Svendborg, Region SyddanmarkAges 19 years+ - NCT06203873Recruiting
Comparing biodegradable vs. metal heart-hole closures for migraine
This trial compares two types of devices (biodegradable vs. metal) to close a small hole in the heart (PFO) in people who have migraine not controlled by usual treatments. It aims to see which device works better to reduce migraine attacks.
Beijing, Beijing MunicipalityAges 18–65 - NCT06204237RecruitingEarly Phase 1
PET imaging safety study for leg artery disease patients and healthy volunteers
This study tests whether a new radioactive tracer called APAC is safe and can be seen in PET/CT scans. It is for people with blocked leg arteries (PAOD/CLI) and for healthy volunteers. The goal is to see where the tracer goes in the body and how the body tolerates it.
GroningenAges 40–85 - NCT06204549Recruiting
Managing health issues to lower heart risk
This trial checks if treating other health problems during a hospital stay can help lower your risk of heart disease or stroke. It is for people who either have never had a heart event but have several risk factors, or who have already had a major heart event.
MontpellierAges 18 years+ - NCT06204744Recruiting
Home arm and hand exercises after stroke
This trial tests a home-based exercise program for people who have weakness in one arm or hand after their first stroke. It aims to help improve movement and function without needing to go to a clinic.
Chiayi CityAges 20 years+ - NCT06205225Recruiting
Mobile health program for heart failure self-care
This study tests a mobile health program (phone app and coaching) to help people with heart failure better manage their condition at home. It aims to improve self-care and reduce hospital visits.
Chicago, IllinoisAges 18 years+ - NCT06205875Recruiting
High vs. low dose pain block after minimally invasive heart valve surgery
This trial compares two doses of a numbing medicine injected into the chest wall to control pain after heart valve surgery. If you qualify, you will receive either a higher or lower dose of the pain block to see which provides better pain relief and recovery.
Hasselt, LimburgAges 18 years+ - NCT06205810Recruiting
Complete study on heart artery blockages
This trial looks at people with a blockage in a heart artery of 50% or more. It tests a new way to check the blockage using a special CT scan. This could help decide the best treatment to prevent future heart problems.
Aalst, Oost-VlaanderenAges 18 years+ - NCT06206369Recruiting
AI tools to predict blood vessel disease risk and progression
This trial uses artificial intelligence to develop better ways to predict the risk and progression of two blood vessel conditions: abdominal aortic aneurysm (a bulging in the main belly artery) and peripheral artery disease (narrowed arteries in the legs). If you have one of these conditions, researchers want to learn from your data to improve future care.
HelsinkiAges 40–90 - NCT06207318Recruiting
Acceptance and commitment therapy before and after bypass surgery
This study tests if Acceptance and Commitment Therapy (ACT), a type of counseling that helps you handle difficult emotions and thoughts, can improve recovery after coronary artery bypass graft (CABG) surgery. It is for people who are scheduled for bypass surgery and can attend video or phone sessions.
Iowa City, IowaAges 18–80 - NCT06207383Recruiting
Comparing heart treatments for atrial fibrillation and heart failure
This study compares two treatments for people with atrial fibrillation and heart failure: one is a procedure to fix the irregular heartbeat (AF ablation), and the other involves a different type of pacing for the heart. It aims to find which approach helps you feel better and stay out of the hospital.
GrazAges 60 years+ - NCT06207552RecruitingEarly Phase 1
Gene therapy study for children with Fabry disease
This study tests a new gene therapy for children aged 7 to 17 with Fabry disease. The treatment aims to fix the faulty gene that causes the condition, which may help reduce symptoms and prevent organ damage.
ShanghaiAges 7–18 - NCT06207591Recruiting
Brain implant study for locked-in communication
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
UtrechtAges 18–70 - NCT06207799RecruitingPhase 2
Drug combo before and after transplant for high-risk myeloma
This trial tests a two-step approach for people with newly diagnosed, high-risk multiple myeloma who are eligible for a stem cell transplant. You'll get a drug called elranatamab before transplant to 'purge' the cancer, and then after transplant, you'll get maintenance therapy guided by how well your cancer is controlled. The goal is to see if this reduces the chance of the cancer coming back.
Houston, TexasAges 18–75 - NCT06209606RecruitingEarly Phase 1
Blood test study for multiple myeloma progression
This study is testing whether a blood test that measures a protein called BCMA can help doctors know if your multiple myeloma is getting worse. You may be able to join if your myeloma has come back or not responded to at least two prior treatments, and you have not taken the drug Ruxolitinib before.
West Hollywood, CaliforniaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.