Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06658899RecruitingPhase 2
Study of CRD-4730 for CPVT (rare heart rhythm disorder)
This study tests an experimental drug called CRD-4730 for people with CPVT, a rare inherited heart rhythm disorder that can cause dangerous fast heartbeats during exercise or stress. The trial will see if the drug can help control these abnormal heart rhythms better than current treatments.
San Francisco, CaliforniaAges 18–99 - NCT06486233Recruiting
Early invasive treatment for elderly heart attack patients
This trial tests whether early invasive treatment (like stenting) is safe and effective for patients 60 or older who have a certain type of heart attack called high-risk non-ST-segment elevation acute coronary syndrome. The goal is to see if this approach improves outcomes for older adults.
Ho Chi Minh CityAges 60 years+ - NCT06486636Recruiting
Pericardiotomy in heart surgery
This trial tests whether opening the sac around the heart (pericardiotomy) during certain heart surgeries can help prevent future heart rhythm problems. It may be an option for people having surgery on the main artery from the heart, heart valves, or heart arteries.
New York, New YorkAges 18 years+ - NCT06486909Recruiting
Shunt need after brain aneurysm bleed: role of early high blood sugar
This study looks at whether high blood sugar levels early after a brain aneurysm bleed affect the need for a shunt (a tube to drain fluid from the brain). It aims to help doctors understand who might need this treatment.
AarauAges 18 years+ - NCT06486818Recruiting
Ablation for premature heartbeats with unknown cause
This trial studies how well a procedure called ablation works for people with a specific type of extra heartbeat that comes from one spot in the heart and has no clear underlying cause. It looks at what predicts success in the short term.
AsyutAges Any age - NCT06486792RecruitingPhase 4
Stroke prevention in patients with hidden atrial fibrillation
This trial tests if starting blood thinners can prevent another stroke in people who had a stroke but were found to have a hidden heart rhythm problem called atrial fibrillation. It is for older adults who have had a recent stroke without a known cause.
Paris, ParisAges 65 years+ - NCT06487130Recruiting
Australia menopause registry study
This study is building a registry to better understand and support Australians going through perimenopause or menopause. By joining, you help researchers learn about the experiences and needs of people in this stage of life.
AdelaideAges 18 years+ - NCT06487585RecruitingPhase 4
Angiotensin II as first pressor after heart surgery
This trial tests if starting Angiotensin II early, instead of other blood pressure medications, can help heart surgery patients maintain safe blood pressure. It may be an option if you have low blood pressure after surgery despite receiving fluids.
Towson, MarylandAges 18 years+ - NCT06487637Recruiting
CardioCare Quest: A game to help you manage high blood pressure
This study tests a new game designed to help people with high blood pressure stick to their treatment. It's made especially for Urban Indigenous adults in the Flagstaff area.
Flagstaff, ArizonaAges 18 years+ - NCT06487780Recruiting
Preventing foot ulcers with a lifestyle program
This trial tests whether a lifestyle program can help people with diabetes avoid new foot ulcers. If you've healed from a foot ulcer in the last year, you may be able to join.
Downey, CaliforniaAges 21 years+ - NCT06488105RecruitingPhase 2
ER Heart Risk Check for Cholesterol Study
This trial tests a new way to check heart risk and start treatment for cholesterol in people coming to the emergency room with chest pain or possible heart attack. It aims to see if early risk assessment and treatment can prevent future heart problems.
Winston-Salem, North CarolinaAges 40–75 - NCT06488898RecruitingPhase 2
Cell therapy to stabilize large abdominal aortic aneurysm
This trial tests whether a special cell treatment can help stabilize a large abdominal aortic aneurysm (AAA) instead of just watching it grow. You may qualify if your aneurysm is at least 5 cm wide and you are scheduled for standard endovascular repair.
MadridAges 18 years+ - NCT06489119Recruiting
Studying plaque types in coronary artery disease with advanced imaging
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
Harbin, HeilongjiangAges 18–85 - NCT06489080Recruiting
Heart attack follow-up study on survival and health
This study looks at how people with heart attacks do over time, including their survival and any heart-related events. It helps doctors understand more about the condition and how to improve care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06489145Recruiting
High-tech rehab program for stroke recovery
This trial tests a high-tech rehabilitation program using an exoskeleton to help people recover arm movement after a stroke. It aims to improve multiple areas of function, like strength and daily activities.
MilanAges 18 years+ - NCT06489470Recruiting
Surgery for severe stroke in the middle cerebral artery
This trial tests a surgery called strobectomy for people with a major stroke in the middle cerebral artery. It might help if you are within 48 hours of symptoms and have no other serious brain conditions.
Rostock, Mecklenburg-VorpommernAges 18 years+ - NCT06490276Recruiting
Biofeedback gait training for stroke survivors
This study tests whether a special gait training program with biofeedback (real-time information about your walking) can improve walking quality in people who have had a stroke. It may help you walk better and more naturally.
TaipeiAges 20–80 - NCT06490250Recruiting
Breathing vs. movement exercises for hypertrophic cardiomyopathy
This study compares two types of gentle exercises—breathing muscle training and a traditional Chinese movement practice called Baduanjin—to see which helps people with hypertrophic cardiomyopathy feel better and improve their daily life. If you have a thickened heart muscle but are stable and have mild symptoms, you may be able to join.
IstanbulAges 18 years+ - NCT06490432Recruiting
Heart Rhythm Study in Fatty Liver Patients
This study is looking at whether people with a common fatty liver condition (MASLD) have abnormal heart rhythms. If you have MASLD and are 18 or older, you may join to help doctors see if your liver affects your heart's electrical activity.
Sohag, SoAges 18 years+ - NCT06491186Recruiting
Pulse check using ultrasound during cardiac arrest
This trial tests whether using an ultrasound on the groin area can quickly check for a pulse in people who have had a cardiac arrest outside the hospital. It may help emergency responders make faster decisions during resuscitation.
ViennaAges 18 years+ - NCT06491667Recruiting
Simple blood tests to predict heart attack recovery
This study is checking if two simple, inexpensive blood tests (NLR and CRP) can help predict how well someone with a certain type of heart attack (STEMI) will do. It aims to find a cheaper way to guide treatment and monitor recovery.
SohagAges 18 years+ - NCT06492265RecruitingPhase 2
Emergency stroke unit study for acute brain attacks
This trial tests a special stroke unit for people having a severe ischemic stroke (a blood clot in the brain). It aims to see if treatment within 4.5 to 6 hours after symptoms start can improve recovery. You may join if you need a procedure to remove the clot.
BeijingAges 18 years+ - NCT06492473Recruiting
Study of VSD in children at Sohag University Hospital
This study looks at children with a common heart defect called a ventricular septal defect (a hole between the lower heart chambers). The goal is to learn more about how this condition affects children and help guide better care.
SohagAges 1 day–16 years - NCT06493227Recruiting
Extended use of bleeding control drugs after heart surgery
This trial is for hospitals, not patients. Hospitals that do many open heart surgeries and whose doctors agree to use certain bleeding control drugs (fibrinolysis inhibitors) as per the study protocol can participate.
Saint PetersburgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.