Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06493994Recruiting
Looking at Myval valve placed through the armpit
This study collects information on people who have already received a new aortic valve through a small cut in their armpit using the Myval valve. Doctors want to see how well this approach works over time.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06494163Recruiting
Exercise Training for Women With Heart Disease
This study compares two types of exercise training (high-intensity interval training vs. moderate-intensity continuous training) to see which is better for women with heart disease. You would be assigned randomly to one of the two exercise programs, and the study would last about 6 months.
Ottawa, OntarioAges 18 years+ - NCT06494436Recruiting
Real-world study of MicroVention devices for aneurysms or stroke
This study collects information from routine medical care to learn how well MicroVention devices work in real-world settings for people being treated for brain aneurysms or stroke from a blocked artery. Your doctor has already decided to use one of these devices as part of your standard treatment.
Vigo, PontevedraAges Any age - NCT06494501RecruitingPhase 3
Preventing heart attacks in middle-aged adults with early plaque
This study tests whether starting cholesterol-lowering treatment early can prevent heart attacks in people aged 30-50 who already have early signs of artery plaque but no history of heart disease.
New York, New YorkAges 30–50 - NCT06495073Recruiting
Finding meaningful change after stroke or TIA in older adults
This study looks at how well two health questionnaires work for people 70 and older who have had a stroke or TIA. The goal is to find the smallest change that matters to patients, so doctors can better track recovery.
Amsterdam, North HollandAges 70–120 - NCT06495450Recruiting
Virtual reality and treadmill training for chronic stroke recovery
This study tests if walking on a treadmill while using a special virtual reality headset can help people improve their walking after a stroke. It is for people who had a stroke at least 6 months ago, can walk with some help, and live near Halifax.
Halifax, Nova ScotiaAges 18 years+ - NCT06495710Recruiting
Arterial Stiffness and Blood Pressure Treatment in Veterans
This study tests whether more intensive blood pressure lowering can improve artery health in older Veterans. You would be randomly assigned to standard or tighter blood pressure control and get free study-related care and monitoring.
Birmingham, AlabamaAges 60 years+ - NCT06495892RecruitingPhase 4
PVP-guided fluid removal for heart failure patients
This study tests a new way to guide fluid removal (decongestive therapy) in people hospitalized for heart failure. It aims to help doctors safely reduce fluid buildup, no matter what type of heart failure you have.
AnkaraAges 18–99 - NCT06495970Recruiting
Pulmonary artery denervation for heart failure with lung hypertension
This trial tests a procedure called pulmonary artery denervation (PADN) for people with heart failure and a certain type of high blood pressure in the lungs (pulmonary hypertension Group 2). The goal is to see if using a special device called the Gradient Denervation System can help control the high pressures and improve your symptoms.
BadalonaAges 22–85 - NCT06496321Recruiting
Comparing two leg vein removal methods for bypass surgery
This trial compares two ways of taking a vein from your leg during heart bypass surgery to see which causes fewer problems. The goal is to find the best method for your recovery.
MontevideoAges 18–70 - NCT06496529Recruiting
Robot arm brace for stroke recovery
This study tests a robotic arm brace (exoskeleton) to help people who recently had a stroke and have trouble moving their arm. The goal is to see if the device can improve arm movement and daily function.
SantiagoAges 18–81 - NCT06497296Recruiting
Best timing for endoscopy after lidocaine spray
This trial looks at when to start an upper endoscopy (EGD) after using a lidocaine throat spray. It aims to find the optimal waiting time to make patients more comfortable during the procedure.
Tainan, Other (Non U.s.)Ages 20–90 - NCT06497738Recruiting
Comparing two drug combos for elderly myeloma
This trial compares two different drug combinations (DRd and VRd-lite) for older adults (65+) who are newly diagnosed with multiple myeloma. The goal is to see which combination works better and is easier to tolerate.
Changzhou, JiangsuAges 65 years+ - NCT06497790Recruiting
Validating a swallowing screening for stroke patients
This study is testing a German version of a swallowing screening tool (BJH-SDS-G) for stroke patients. It aims to identify swallowing problems early.
Giesen, HesseAges 18–100 - NCT06497881Recruiting
How well your arm moves after a stroke
This study looks at how well your arm and hand move after a stroke. If you join, researchers will check your movement quality to learn more about recovery. You must be 18 or older, have been independent before your stroke, and be a patient at Adi-Negev Nahalat-Eran.
OfakimAges 18–85 - NCT06498011Recruiting
Training to improve arm and hand function after stroke
This study tests a new type of training that combines thinking, feeling, and moving to help improve arm and hand function after a stroke.
Toronto, OntarioAges 18 years+ - NCT06498089RecruitingPhase 4
Comparing tailored vs. standard treatment for active Takayasu's arteritis.
This trial compares a personalized treatment plan based on your specific disease markers to standard care, aiming to find which is more effective and safer for active Takayasu's arteritis. It may help researchers learn how to better control inflammation and prevent flares.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06498323RecruitingPhase 4
Comparing TNK vs TPA for stroke in a mobile unit
This trial compares two clot-busting medicines, TNK and TPA, given through an IV in a special ambulance (Mobile Stroke Unit) to treat acute ischemic stroke. The goal is to see which drug works better when started quickly after symptoms begin.
BangkokAges 18 years+ - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75 - NCT06499961Recruiting
Digital health program for belly fat, blood pressure, and stress
This trial tests a digital program to help people with belly fat, high blood pressure, blood sugar, cholesterol, and stress-related symptoms like chronic pain or bad mood. It aims to improve your health through education and support you can do on a tablet or computer.
Hong KongAges 50 years+ - NCT06500611Recruiting
Sensory balance exercises for stroke recovery
This trial tests if combining sensory integration and vestibular exercises helps improve balance in people who have had a stroke and also have dizziness or balance problems. It may help you walk better and feel steadier.
Lahore, Punjab ProvinceAges 40–65 - NCT06500728Recruiting
Vision involvement in giant cell arteritis
This study looks at how vision is affected in people with giant cell arteritis (GCA) -- a condition where blood vessels become inflamed. It compares those with GCA-related vision loss to people who have similar vision problems but not from GCA, to better understand and treat these eye issues.
Milan, LombardyAges 18 years+ - NCT06500988Recruiting
Smartphone app for atrial fibrillation and weight management
This study uses a smartphone app and activity tracker to help people with atrial fibrillation (an irregular heartbeat) and a higher body weight manage their condition through tailored exercise guidance.
Baltimore, MarylandAges 18 years+ - NCT06500884RecruitingPhase 2
Preventing mouth problems from GPRC5D therapy in myeloma
This study tests a preventive treatment for mouth or taste problems that can be caused by a newer type of multiple myeloma therapy. It aims to help people who have already tried several standard treatments and whose disease is still active.
San Francisco, CaliforniaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.