Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06645990Recruiting
Comparing Heart Pumps for Shock With ECMO
This study compares two support devices (Impella vs. IABP) for people with cardiogenic shock who are already on ECMO. It looks at how well the left side of the heart recovers when one of these devices is added.
MontpellierAges 18 years+ - NCT06646250Recruiting
New ultrasound for steady brain monitoring in newborns
This trial uses a new ultrasound device (NeoDoppler) to watch blood flow in a baby's brain continuously. It aims to see if this gentle, bedside tool can help doctors monitor babies—especially those born early or with certain health concerns—without moving them.
TrondheimAges birth–1 year - NCT06646484Recruiting
Using a device to check hydration after brain bleeding
This study tests a new way to monitor your body's water and sodium levels using a simple, painless device (impedancemetry) after a subarachnoid hemorrhage. It may help doctors better manage your hydration and prevent complications during your ICU stay.
Lyon, FranceAges 18 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06647251Recruiting
Comparing different radiofrequency modes for atrial fibrillation ablation
This trial tests three different ways of delivering radiofrequency energy using a specific catheter (QDOT) during a first-time procedure to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to find which method works best for patients with recent or short-lasting AF episodes.
Paris, ParisAges 18 years+ - NCT06647485Recruiting
Pulsed Field Ablation for Paroxysmal Atrial Fibrillation
This trial studies a new procedure called pulsed field ablation to treat brief episodes of atrial fibrillation (AFib). The goal is to see if it can help reset the heart's natural electrical system and reduce symptoms.
Aalst, BelgiumAges 18–70 - NCT06647511Recruiting
Digital health study for pregnant refugees in NYC
This study tests a smartphone-based tool to help pregnant refugees and asylum seekers stay healthy during pregnancy. It aims to reduce complications and improve care for mothers and babies.
New York, New YorkAges 18 years+ - NCT06647641Recruiting
Genetics study for PSP, CBS, MSA, and related conditions
This study looks at genetic factors in people with PSP, CBS, MSA, or similar brain conditions, and also in their family members. It involves genetic testing to learn more about these diseases and may help find new treatments.
Boston, MassachusettsAges 35 years+ - NCT06647745RecruitingPhase 3
Study for type 2 diabetes and high blood pressure
This study tests a new combination of three medications (THP-00101, THP-00102, and THP-00103) for people with type 2 diabetes and essential high blood pressure. It aims to see if this combination is safe and effective compared to standard treatments.
SeoulAges 19 years+ - NCT06647927Recruiting
Genetic study for better Brugada diagnosis
This study looks at the genes of people with Brugada Syndrome to find new markers that can help doctors diagnose it more accurately. If you have Brugada Syndrome, joining could help improve understanding and care for this condition.
San Donato Milanese, MilanAges 18 years+ - NCT06648278Recruiting
Support and technology study for breast cancer patients
This trial tests a program called PONTS 2.0 that uses phone texts and online tools to support breast cancer patients through their treatment. It aims to make it easier for patients to get the help they need.
San Francisco, CaliforniaAges 18 years+ - NCT06648733Recruiting
Better medication safety when leaving the hospital for palliative care
This trial studies how to improve medication management when patients with advanced illnesses move from hospital care to home care in Muenster. It aims to make the switch smoother and safer for people who need palliative (comfort-focused) treatment.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06648954Recruiting
Brain stimulation to improve hand movement in chronic stroke
This study tests whether a brain stimulation technique called high-definition transcranial direct current stimulation (HD-tDCS) can help improve hand and arm movement in people who had a stroke more than a year ago. The stimulation targets the parts of the brain that control movement, and the goal is to see if it can boost recovery when combined with standard therapy.
Hong KongAges Any age - NCT06649097Recruiting
Brain clot removal using continuous fluid irrigation
This trial tests a system that continuously bathes the brain with fluid to wash away blood after a brain bleed, which may help recovery.
New York, New YorkAges 18 years+ - NCT06649240Recruiting
Best LDL cholesterol goal after small vessel stroke
This trial is testing the best target for 'bad' cholesterol (LDL) after a type of stroke caused by a small blocked vessel. You would be in one of two groups to see which LDL level helps prevent another stroke the most.
AnsanAges 19 years+ - NCT06649305Recruiting
Study of vulnerable plaque in heart arteries of people with diabetes
This study uses a special camera (OCT and NIRS) inside heart arteries to look for dangerous plaque in people with diabetes. It may help doctors decide the best treatment to prevent heart attacks.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06649968Recruiting
Testing a smart glove for hand recovery after stroke
This trial tests a high-tech glove that helps track and improve hand and arm movement after a stroke. It may be an option for people who had a stroke 1 to 6 months ago and have mild to moderate arm weakness.
AcerenzaAges 18 years+ - NCT06650436Recruiting
Stroke, Delirium, and Long-Term Thinking Changes
This study looks at the link between stroke, delirium (sudden confusion), and long-term thinking problems. It tests whether EEG and MRI scans can help predict who may have trouble thinking clearly after a first stroke.
BrusselsAges 18 years+ - NCT06650826Recruiting
Antibodies and blood clots in young adults
This study looks for certain antibodies in the blood of people aged 18 to 60 who have had a blood clot without a clear cause, or soon after an infection or vaccine, or who have had clots return despite treatment. It aims to understand why these clots happen.
BerlinAges 18–60 - NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT06651255Recruiting
Algorithm-guided care for bleeding in Von Willebrand disease
This trial tests whether a special algorithm can reduce repeat bleeding from the gut or nose in people with inherited Von Willebrand disease. If you have had serious nosebleeds or digestive bleeding, this study may help find a better way to manage your condition.
Lille, NordAges 18 years+ - NCT06652750Recruiting
5G cloud-based check-up for heart device patients
This study tests whether a 5G-based remote check-up (over the cloud) is safe and effective for people with certain implanted heart devices, like pacemakers. You'll skip your first clinic visit and instead use a video call or remote check to see how your device is doing.
Guangzhou, GuangdongAges 18 years+ - NCT06653348RecruitingPhase 2/Phase 3
Ticagrelor-based therapy for recent mild stroke or high-risk TIA
This trial tests whether switching to a simpler antiplatelet medication (ticagrelor) after a mild stroke or high-risk TIA can prevent another stroke while reducing the risk of bleeding. It is for people who have not received clot-busting treatment or had a large stroke.
Sari, MazandaranAges 40 years+ - NCT06653387Recruiting
Testing a new carotid stent with blood-flow reversal for high-risk patients
This trial tests a new carotid stent system used with a special blood-flow reversal device to treat blocked carotid arteries. It is for people with high-risk conditions who might not be good candidates for traditional open surgery, and aims to see if the stent is safe and effective in preventing strokes.
Sacramento, CaliforniaAges 18–79
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.