Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06653556RecruitingEarly Phase 1
LCAR-AIO for relapsed or hard-to-treat lupus
This study tests a new treatment called LCAR-AIO for people with systemic lupus erythematosus (SLE) that has come back or not responded well to standard therapies. The goal is to see if it can help control the disease.
Wuhan, HubeiAges 18–65 - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06653946RecruitingPhase 4
Predicting bleeding after stroke treatment in patients with atrial fibrillation
This trial looks at why some patients with a first-time stroke caused by atrial fibrillation experience bleeding in the brain after receiving clot-busting medication. It aims to find factors that predict this bleeding, which could help doctors choose safer treatments in the future.
Kafr ash ShaykhAges 18–75 - NCT06654375Recruiting
Late stroke treatment with clot removal or medication
This trial compares a procedure to remove a large blood clot from the brain (thrombectomy) with standard medical care for people who had a stroke 24 to 72 hours ago but still have some blood flow around the clot. It aims to see if the procedure can help improve recovery even when started later than usual.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06654401Recruiting
Using electrical shock to restore normal heart rhythm after surgery
This study looks at whether giving an electrical shock (cardioversion) right after heart surgery can help people with long-lasting atrial fibrillation keep a normal heartbeat. It may help guide future treatment decisions for patients who have not gotten better with medication.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06655402Recruiting
Home rehab program for stroke survivors and their caregivers
This trial tests a video-based rehab program for stroke survivors and their caregivers done at home. It may help improve arm function and support the caregiver's role.
Atlanta, GeorgiaAges 18 years+ - NCT06655376RecruitingPhase 4
Aspirin study for advanced heart failure with a heart pump
This trial tests if taking aspirin along with a standard blood thinner helps people with a HeartMate3 heart pump have fewer bleeding or clotting problems. It is for people who have had their pump for at least 3 months.
Chicago, IllinoisAges 18 years+ - NCT06655480RecruitingPhase 2
Triple drug therapy for advanced heart failure with preserved ejection fraction
This trial tests a combination of three heart failure drugs (ARNI, SGLT2i, MRA) to see if they improve symptoms and outcomes in people with a type of heart failure where the heart pumps normally but doesn't relax properly (HFpEF).
MoscowAges 40–80 - NCT06655636Recruiting
Testing a new robotic brace to help stroke survivors open their hand
This trial tests a wearable robotic device (ExoNET) that helps stroke survivors with hand weakness. It aims to see if the device is safe and helpful for people who had a stroke at least 8 months ago and still have trouble using their arm and hand.
Chicago, IllinoisAges 40–70 - NCT06655675Recruiting
Blood flow changes after epidural pain relief in labor
This study looks at how a type of labor pain relief (combined spinal-epidural) affects blood flow in the mother and baby's main arteries. It may help doctors understand if this common pain relief method is safe for all labors.
Toronto, OntarioAges 18–50 - NCT06655922Recruiting
FAPI scan to assess chronic total heart artery blockages
This study is testing whether a special type of PET scan (called FAPI) can better see and understand fully blocked heart arteries (chronic total occlusions). If you're scheduled to have angioplasty to open such a blockage, this imaging might help guide the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06656754RecruitingEarly Phase 1
IsoReach: A study on reaching after stroke
This trial tests a new way to measure how people reach for objects, looking at differences between healthy adults and those who have had a stroke. The goal is to understand how stroke affects movement so better therapies can be developed.
Chicago, IllinoisAges 18 years+ - NCT06656988RecruitingPhase 3
Saving kidney function during leg artery treatment with carbon dioxide
This trial tests if using carbon dioxide gas instead of standard dye during a leg artery procedure can protect the kidneys. It is for people with blocked leg arteries who also have reduced kidney function.
InnsbruckAges 18 years+ - NCT06657235Recruiting
Stroke recovery program to improve health after a stroke
This study tests a transitional care program for people who have had an ischemic stroke. It aims to help you manage risk factors and improve your health after leaving the hospital, using telemedicine visits.
Winchester, VirginiaAges 30 years+ - NCT06657326Recruiting
New stent for high bleeding risk patients
This trial tests a new type of stent (BioFreedom Ultra) compared to a standard one (BioFreedom) in people who have a high risk of bleeding. Both stents release medicine to keep arteries open, and the study checks if the newer stent works better with a shorter course of blood thinners.
Johor Bahru, JohorAges 18 years+ - NCT06657404Recruiting
Modified 'Pills-in-the-Pocket' strategy for AF after ablation
This study tests a modified 'pills-in-the-pocket' approach—taking antiarrhythmic drugs only when symptoms occur—for people with non-valvular atrial fibrillation (AF) who still have arrhythmias lasting over 24 hours after their first catheter ablation. It aims to see if this strategy can safely control symptoms without needing daily medication.
Guangzhou, GuangdongAges 18 years+ - NCT06657794Recruiting
Custom graft repair for aortic aneurysms near the kidneys
This trial tests a doctor-modified stent-graft to fix an aneurysm in the part of the aorta just below the kidney arteries. It may be an option if standard devices cannot be used or are not available in time.
Cleveland, OhioAges 18 years+ - NCT06657911Recruiting
Studying a new sizing method for bicuspid aortic valves
This trial looks back at people with a specific type of bicuspid aortic valve (a valve with two flaps instead of three) who had a transcatheter aortic valve replacement. Researchers want to see how well a special sizing method called LIRA worked for choosing the right valve size.
Brescia, ItalyAges 18 years+ - NCT06657924RecruitingPhase 2
TXA to Prevent Bleeding in Colorectal Surgery
This trial tests a medicine called tranexamic acid (TXA) given right before major colorectal surgery to see if it helps reduce bleeding. If it works, it could make surgery safer for people like you.
Cleveland, OhioAges 18–100 - NCT06658197RecruitingPhase 3
Comparing a new clot-busting drug for severe stroke
This study tests a medication called tenecteplase, given before a procedure to remove a large blood clot in the brain. It may help people who have had a severe stroke within the last 4.5 hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06658496Recruiting
Studying kidney health in very premature newborns
This trial looks at how well kidneys work in very premature babies (born before 32 weeks). It uses special sensors to monitor kidney health in the first few days of life.
Madison, WisconsinAges 1 minute–1 week - NCT06659276Recruiting
Comparing two imaging methods for multiple myeloma
This trial compares two whole-body imaging scans (full-body MRI using DWI and a PET/CT scan) to see which does a better job detecting and staging active multiple myeloma. If you have been newly diagnosed or are being evaluated for suspected symptomatic myeloma, joining could help doctors learn which test is best for planning your care.
BolognaAges 18 years+ - NCT06659367Recruiting
FFR/QFR registry for heart artery assessment
This study collects information from people who have had a standard heart test called FFR to measure blood flow in their arteries. It aims to better understand how this test helps guide treatment.
BelgradeAges 18 years+ - NCT06660186Recruiting
Sternal plating for high-risk heart surgery patients
This study looks at whether using special metal plates to close the breastbone after heart surgery can help people at higher risk for slow healing. It may be an option if you have multiple risk factors like diabetes, heavy smoking related lung disease, or obesity.
Cleveland, OhioAges 18–89
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.