Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06639360Recruiting
Magnetic stimulation after clot removal for stroke recovery
This trial tests whether adding magnetic brain stimulation (TMS) after clot-removal surgery can help people recover better from a stroke. It is for people who had a moderate-to-severe stroke in the front part of the brain and had the clot removed.
Xi'an, ShaanxiAges 18–80 - NCT06639737Recruiting
Optimizing blood volume before surgery using heart ultrasound
This trial tests whether using a heart ultrasound before surgery can help doctors better manage your blood volume. If you are having surgery under general anesthesia and have a higher risk of heart problems, this study may help improve your safety.
Caen, NormandyAges 18–99 - NCT06640101Recruiting
Breathing muscle training for stroke recovery
This trial tests whether a simple breathing exercise device can help people recovering from stroke. You may benefit if you had a stroke up to 12 months ago and can walk a short distance on your own.
Shenzhen, None SelectedAges 40–80 - NCT06640751Recruiting
Helping people with hypertension improve health habits
This study tests whether a program to support healthy behaviors can help people with high blood pressure better control their condition. It is for people whose blood pressure is not well managed or who find it hard to stick with treatment.
Nanjing, JiangsuAges 18–80 - NCT06641362Recruiting
Ultra-high frequency ECG for heart timing problems
This study tests a new, more detailed type of ECG (called UHF-ECG) to see if it can better detect uneven electrical timing in the heart. If you are getting your first pacemaker for a slow heart rate or heart failure, this study may help doctors personalize your treatment.
Avondale, ArizonaAges 18 years+ - NCT06641336Recruiting
Perceptions of a mixed reality system for stroke recovery
This study tests a new mixed reality (like virtual reality) system called RehAtt to see if it can help people recover arm and hand movement after a first stroke. It is for people who have weakness on one side and can understand instructions.
LjubljanaAges 18 years+ - NCT06641505Recruiting
Deep breathing test to guide fluid before surgery in older adults
This trial uses a simple breathing test to see how the internal jugular vein (a large vein in the neck) changes with deep breaths. The goal is to guide how much fluid to give before surgery, which may help older patients stay stable during the operation.
Jiaxing, ZhejiangAges 60–80 - NCT06642168Recruiting
Genetic Testing for Sudden Cardiac Arrest in Young Athletes
This study looks at young people who had a sudden cardiac arrest during sports. Doctors will check for genetic causes to help prevent future events in athletes and their families.
Paris, FranceAges 12–35 - NCT06642272RecruitingPhase 4
Comparing two diabetes drugs in real-world use
This trial compares two common diabetes medications, empagliflozin and dapagliflozin, to see which works better in everyday practice. It aims to find the best treatment option for patients with type 2 diabetes.
CopenhagenAges 18 years+ - NCT06642623RecruitingPhase 4
Study on heart and kidney health in type 2 diabetes
This trial tests enavogliflozin (a newer SGLT2 inhibitor) compared to older drugs (dapagliflozin or empagliflozin) to see how well it protects the heart and kidneys in people with type 2 diabetes.
SeoulAges 19 years+ - NCT06642870Recruiting
Self-management programme for rare rheumatic conditions
This trial is developing a self-management programme for people with rare rheumatic conditions like lupus, vasculitis, myositis, or Sjogren syndrome. It aims to help participants better manage their condition and improve their quality of life.
BristolAges 18 years+ - NCT06643013Recruiting
Targeting brain blood vessels to help small vessel disease
This study tests a drug that targets a protein called TSPO to see if it can improve the function of the cells lining the small blood vessels in the brain of people with cerebral small vessel disease. It may help with mild memory or thinking problems.
LondonAges 60–90 - NCT06643130RecruitingPhase 3
Testing a combo treatment for high blood pressure and cholesterol
This study tests whether adding two medications together helps people who have both high blood pressure and high cholesterol. It aims to see if the combination works better and is safe.
SeoulAges 19 years+ - NCT06643273Recruiting
Glove to measure touch feeling after stroke
This study tests a special glove that helps measure how well you can feel touch after a stroke. It's for people who had a single stroke within the last 6 months and have some thinking and memory ability.
Florence, ItalyAges 18–85 - NCT06643598Recruiting
Virtual and lived-experience support for newborns with brain challenges
This study tests whether a program that combines virtual support and a peer who has been through it can help parents of newborns with certain brain conditions. It is designed for families living in rural areas and aims to improve children's recovery.
Madison, WisconsinAges Up to 5 years - NCT06643819RecruitingPhase 3
Testing a new blood pressure drug
This trial tests a new combination blood pressure medicine called CKD-202A. It is for adults with high blood pressure who have not had other treatments or conditions that could affect the results.
WŏnjuAges 19 years+ - NCT06644118RecruitingPhase 1
Study of OL-101 for people with relapsed or refractory multiple myeloma
This trial tests a new treatment called OL-101 for people whose multiple myeloma has come back or stopped responding to at least three prior treatments, including a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 antibody. It aims to see if OL-101 can help control the disease.
Beijing, Beijing MunicipalityAges 18–75 - NCT06644443RecruitingPhase 1/Phase 2
BCMA-GPRC5D CAR-T cells for relapsed multiple myeloma
This trial tests a new kind of immunotherapy that uses your own immune cells, called CAR-T cells, to target two specific markers (BCMA and GPRC5D) found on myeloma cells. It's for people whose multiple myeloma has come back or stopped responding to earlier treatments.
Shenzhen, GuangdongAges 18–75 - NCT06644625Recruiting
CHAAMP study: MGUS screening for Black adults and relatives
This study screens for MGUS, a precursor to certain blood cancers, in people who are Black or African American, or who have a close relative with a plasma cell disorder. If MGUS is found, you may be invited to continue in the study to monitor your health.
Charlotte, North CarolinaAges 30 years+ - NCT06644742Recruiting
PKP2 heart condition natural history study
This study is for people with a specific genetic heart condition (PKP2-related arrhythmogenic cardiomyopathy) who already have an ICD. It does not test a new treatment but instead follows participants over time to learn more about the condition.
Boston, MassachusettsAges 12 years+ - NCT06644963Recruiting
Impella heart pump study: safety and complications
This study reviews how well people tolerated the Impella heart pump during cardiogenic shock and what complications occurred. It looks at past cases from 2010 to 2022 to help doctors understand the safety of this device.
MontpellierAges 18 years+ - NCT06645405Recruiting
AI scan reading for stroke caused by large vessel blockage
This trial tests whether an AI program can better read CT scans to find large blood vessel blockages that cause stroke. If you had a stroke from a blocked large vessel and already had CT scans, the AI may help doctors decide on treatment faster.
Shanghai, Shanghai MunicipalityAges 18–95 - NCT06645678RecruitingPhase 1/Phase 2
Mezigdomide and Elranatamab for relapsed or hard-to-treat multiple myeloma
This trial tests two drugs, mezigdomide (a pill) and elranatamab (an injection), in people whose multiple myeloma has come back or not responded to at least two prior treatments. It aims to see if this combination is safe and effective.
SingaporeAges 19 years+ - NCT06645691RecruitingPhase 2
Heart and metabolic imaging study using a special MRI scan
This study tests a new MRI method that uses a safe, natural substance (pyruvate) to take detailed pictures of the heart and metabolism. It may help doctors better understand heart disease, diabetes, and related conditions.
SingaporeAges 21–99
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.