Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06756282Recruiting
Pacemaker use one year after TAVR
This study looks at people who need a permanent pacemaker after having a TAVR procedure (a type of heart valve replacement). It aims to see how many people still need the pacemaker one year later.
MontpellierAges Any age - NCT06757049Recruiting
Using the Edwards MITRIS RESILIA valve in Asian patients
This study looks at how well a new mitral valve (the Edwards MITRIS RESILIA) works in people of Asian descent. It aims to see if this valve is safe and effective for patients who need mitral valve replacement.
Seoul, SONGPA-GUAges 19 years+ - NCT06758375RecruitingPhase 2
Low dose teclistamab for newly diagnosed multiple myeloma
This trial tests a lower dose of the drug teclistamab in people newly diagnosed with multiple myeloma. It aims to see if a lower dose is still effective and has fewer side effects.
Monterrey, Nuevo LeónAges 18 years+ - NCT06757764RecruitingPhase 4
Stroke from artery narrowing: testing combination of anti-platelet drugs
This trial tests whether a combination of two or three anti-platelet medicines (like aspirin, clopidogrel, or cilostazol) is safe and works better than one alone for people who had a stroke from a narrowed artery. The goal is to prevent another stroke.
Seoul, Songpa-guAges 20 years+ - NCT06758128Recruiting
Genes and immunity in worsening heart failure
This study looks at how your genes and immune system affect heart failure. Researchers want to understand why some people have flare-ups (exacerbations) and how the body responds.
San Giovanni Rotondo, FoggiaAges 18 years+ - NCT06758271Recruiting
Long-term study of avacopan for vasculitis
This study looks at the long-term safety and effectiveness of avacopan in people with certain types of vasculitis (GPA or MPA). It may help doctors understand how well the medicine works over time.
Multiple LocationsAges Any age - NCT06758505Recruiting
Stroke recovery study: social activities after stroke
This study tests a rehabilitation program to help people who have had a stroke get back to the social activities they enjoyed before. If you have trouble joining in activities with family or friends, this program may help you reconnect.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06758609Recruiting
Brain cooling plus clot removal for large artery stroke
This trial tests a new treatment that combines cooling the brain with a catheter and removing the clot to restore blood flow — for people who have had a major stroke in the front part of the brain within the last 24 hours.
Guangzhou, GuangdongAges 18–85 - NCT06758648Recruiting
Eye blood vessels in Fabry disease
This study looks at the tiny blood vessels in the eyes of people with Fabry disease using a special camera. It may help doctors understand how the disease affects the eyes over time.
München, BavariaAges 18 years+ - NCT06758713RecruitingPhase 1
Gene-therapy treatment for blood cancers: safety and early effects
This trial tests a new kind of gene therapy (fourth-generation CAR-T) for several types of blood cancers including lymphoma, leukemia, and myeloma. It aims to see if the treatment is safe and starts to work against the cancer.
Guangzhou, GuangdongAges 18–75 - NCT06758921Recruiting
Testing a catheter for leg artery blockages
This study tests a special catheter to open blocked arteries in the thigh, knee, or lower leg. It may help improve blood flow and reduce symptoms like leg pain or wounds.
GrazAges 18 years+ - NCT06759103Recruiting
Study of patients with aortic coarctation
This study collects information from people diagnosed with aortic coarctation before or shortly after birth, to better understand the condition and improve care. It may be a fit if you or your child were diagnosed before or within one month of birth.
BolognaAges Any age - NCT06759181RecruitingPhase 1/Phase 2
CAR-T targeting BCMA and FcRL5 for relapsed/refractory myeloma
This trial tests a new type of immunotherapy called CAR-T cells that target two proteins (BCMA and FcRL5) on myeloma cells. It is for people whose myeloma has returned or not responded to other treatments.
XuzhouAges 18–70 - NCT06759389Recruiting
Ventor study for cardiac arrest outside the hospital
This trial is testing a new device or procedure for adults who have a cardiac arrest outside the hospital. It aims to see if it can help improve outcomes for patients like you.
Stony Brook, New YorkAges 18–75 - NCT06759428Recruiting
Chronic subdural hematoma patient registry study
This study collects information from patients diagnosed with chronic subdural hematoma (a type of bleeding on the brain) to better understand the condition and its treatment. By participating, you help doctors learn more about what helps patients recover.
AmsterdamAges 18 years+ - NCT06759753RecruitingPhase 2
Aleeto for acute ischemic stroke: a randomized trial
This trial tests a drug called Aleeto in people who have had an acute ischemic stroke (a stroke caused by a blocked blood vessel) within the last 72 hours. It aims to see if Aleeto can improve recovery and reduce disability.
BeijingAges 30–80 - NCT06761144Recruiting
Detecting blood clots in lungs of cancer patients in the ER
This trial studies how to quickly and safely rule out blood clots in the lungs of cancer patients who come to the emergency room. It aims to help doctors make faster decisions and avoid unnecessary treatments for people with cancer.
BolognaAges 18 years+ - NCT06761365Recruiting
Testing a new device for unruptured brain aneurysms
This trial tests a new device to block blood flow into unruptured brain aneurysms (balloon-like bulges). It is for adults whose aneurysm has not bled and fits specific size requirements. The goal is to see if the device is safe and works well.
SofiaAges 18–80 - NCT06761404Recruiting
Non-invasive nerve stimulation for stroke recovery
This trial tests if a non-invasive nerve stimulation device can help improve arm and hand function in people who had a stroke more than six months ago. The stimulation is gentle and applied to the ear, aiming to aid recovery.
Houston, TexasAges 18 years+ - NCT06762561Recruiting
Mesh reinforcement after open aneurysm repair
This study is looking back at patients who had open surgery for an abdominal aortic aneurysm with a special mesh placed to prevent future hernias. Researchers want to see how well the mesh worked over time.
Villars-sur-GlâneAges 18 years+ - NCT06762717Recruiting
FARAPULSE pulsed field ablation for heart rhythm problems
This trial tests a new type of energy (pulsed field) to treat abnormal heart rhythms. It may be less damaging to nearby tissues than traditional ablation.
Beijing, China/BeijingAges 18 years+ - NCT06762795Recruiting
Gene study for newborns with HIE on cooling therapy
This study uses whole genome sequencing to look at the genes of newborns with HIE (brain injury from lack of oxygen) who are receiving cooling treatment. The goal is to learn more about how genes may affect recovery and outcomes.
Houston, TexasAges birth–1 year - NCT06763055RecruitingPhase 3
Study of two drugs for spontaneous brain bleed recovery
This trial compares two medicines (deferoxamine and colchicine) to see if they can prevent further brain damage after a spontaneous brain bleed (intracerebral hemorrhage). The goal is to improve recovery by reducing inflammation and iron-related damage.
Sydney, New South WalesAges 18–80 - NCT06763458Recruiting
Balloon angioplasty for minor unstable stroke with brain artery narrowing
This trial tests if balloon angioplasty (opening a narrowed artery with a tiny balloon) can help people who have had a minor stroke and are still having symptoms despite taking blood thinners.
ShenyangAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.