Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06764225Recruiting
Low-Sodium Salt for Heart Failure Patients
This study tests whether using a low-sodium salt substitute can help people with heart failure live longer, avoid hospital visits, and feel better. It's for adults with a weakened heart pump who have a caregiver and eat home-cooked meals.
Beijing, Beijing MunicipalityAges 18–75 - NCT06764290Recruiting
Brain changes when walking after stroke
This study looks at how the brain changes after a stroke when people walk on different surfaces. It may help understand why walking can be harder and how therapy could improve it.
Nanjing, JiangsuAges 18–70 - NCT06764797RecruitingPhase 3
Virtual reality and brain stimulation for arm recovery after stroke
This trial tests whether combining virtual reality mirror therapy with a gentle brain stimulation technique can improve arm and hand movement in people who have had a stroke. It may be an option if you have moderate to severe arm weakness and it has been more than three months since your stroke.
Riyadh, Riyadh RegionAges 18 years+ - NCT06765265RecruitingPhase 4
Comparing two statins' effect on vitamin D after heart attack
This study compares two common statins (atorvastatin and rosuvastatin) to see how they affect vitamin D levels in people who have recently had a heart attack or unstable angina. It may help doctors choose the best statin for your heart and vitamin D health.
Lahore, Punjab ProvinceAges 18–65 - NCT06765226Recruiting
Study of used Impella heart pumps
This study looks at used Impella heart pumps to see what deposits build up on them during treatment. If you've had an Impella pump for a certain length of time, this study helps doctors learn more about the device.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06765642Recruiting
Brain stimulation for hand strength after stroke
This study tests whether a safe, non-invasive brain stimulation technique (called rTMS) can improve hand strength and movement in people who have had a stroke at least 3 months ago. The treatment is delivered through a coil placed on the scalp and does not require surgery.
Durham, North CarolinaAges 21 years+ - NCT06766006Recruiting
Heart-lung machine left ventricle unloading study
This study looks at how to best relieve pressure on the heart while a heart-lung machine is helping to pump blood. It includes anyone who needs this support.
MaastrichtAges 1 day–80 years - NCT06766422Recruiting
AI tool to better detect and predict brain aneurysm risk
This study uses artificial intelligence to help doctors better see and understand brain aneurysms from MRI or CT scans. It aims to improve how accurately aneurysms are found and whether they are stable or at risk of rupturing.
ShanghaiAges 18 years+ - NCT06767254Recruiting
Using AI to predict early return of multiple myeloma
This study uses artificial intelligence to analyze how multiple myeloma may lead to early relapse. It may help doctors better predict and manage the disease.
Meldola, Forlì-CesenaAges 18 years+ - NCT06767345RecruitingPhase 4
Comparing two cholesterol medicines for plaque stabilization
This study compares two ways to lower cholesterol and stabilize artery plaque in people with coronary artery disease who are having a stent procedure. It tests whether a moderate statin plus ezetimibe works as well as a high-intensity statin alone for stabilizing plaque.
Seoul, SeoulAges 18 years+ - NCT06767501Recruiting
Amnion graft for diabetic foot ulcers vs. standard care
This trial tests whether a special amnion membrane graft can help heal diabetic foot ulcers better than standard care alone. If you have a diabetic foot ulcer that hasn't healed after standard treatment, this study may offer a new option.
Roanoke, VirginiaAges 18 years+ - NCT06767631Recruiting
Muscle and nerve changes after botox for stroke foot tightness
This study looks at how botulinum toxin (botox) injections affect the muscles, tendons, and nerves in the lower leg of people who have had a stroke and have a tight, twisted foot (equinovarus). It aims to understand these changes to improve future treatments.
LeuvenAges 40–60 - NCT06767605Recruiting
Spanish registry for autoimmune liver diseases
This study collects information from people with autoimmune or cholestatic liver diseases to better understand them and improve care. It does not test a new treatment, but your participation can help future research.
BarcelonaAges 18 years+ - NCT06767657Recruiting
Immediate vs delayed surgery for recent mini-stroke or mild stroke
This trial compares two approaches for treating a blocked carotid artery after a mini-stroke or mild stroke: surgery done right away (within hours) versus waiting a short while. The goal is to see which timing helps prevent another stroke better.
FlorenceAges 45–90 - NCT06768008Recruiting
Integrated care model for newborns with critical heart disease
This trial tests a coordinated treatment plan for newborns with critical congenital heart disease, starting before birth and continuing after delivery. It aims to improve outcomes for babies who need two-ventricle repair surgery.
BeijingAges 1 day–4 weeks - NCT06768138RecruitingPhase 3
Giving clot-busting medicine directly into the brain after successful blood flow restoration
This trial tests whether a clot-busting drug given directly into the brain artery can improve recovery after a major stroke caused by a blockage in the front part of the brain. The study is for people whose blood flow has already been successfully restored with standard treatments.
NancyAges 18 years+ - NCT06768398Recruiting
AI study for heart and blood vessel health
This study uses artificial intelligence (AI) to analyze medical images of blood vessels. It aims to help patients with heart or blood vessel conditions, including smokers and those with high blood pressure, by improving how doctors spot problems early.
ShatinAges 19 years+ - NCT06768437Recruiting
Heart fat and preserved ejection fraction heart failure trial
This study looks at whether fat around the heart affects a type of heart failure where the heart pumps well but is stiff (HFpEF). You may be able to join if you have this condition, are 18 or older, and can understand English.
Leicester, LeicestershireAges 18 years+ - NCT06768528Recruiting
Galectin-3 and atrial fibrillation after heart bypass
This trial checks if a protein called galectin-3 can help predict who will develop an irregular heartbeat (atrial fibrillation) after coronary artery bypass surgery. It aims to find ways to better monitor and treat heart patients after surgery.
São Paulo, São PauloAges 18 years+ - NCT06769256RecruitingPhase 4
TNK vs tirofiban for heart attack with large clot
This trial tests a clot-busting drug (TNK) versus a blood thinner (tirofiban) in people having a major heart attack with a large clot. If you qualify, you would get the medicine directly into your heart artery through a thin tube to see which works better.
Zhengzhou, HenanAges 18–75 - NCT06769269Recruiting
Hypertension registry study in Morocco
This study is creating a registry of people with high blood pressure in Morocco. It aims to understand different types of hypertension, related health problems, and how to personalize treatment.
Meknes, MoroccoAges 18 years+ - NCT06769529Recruiting
Study of adults with congenital heart disease
This study follows adults born with a heart condition to see how they do over time, whether they had surgery or not. It aims to learn more about their health journey.
BolognaAges 18 years+ - NCT06769672Recruiting
Walking and thinking training with brain stimulation for stroke recovery
This study tests whether combining dual-task training (walking while doing a thinking task) with a gentle brain stimulation technique called tDCS can improve how stroke survivors move and think. It may help you walk safely while also paying attention to other tasks.
Hong KongAges 50 years+ - NCT06769880Recruiting
Heart health screening and referral for early stage heart failure
This study tests whether bedside ultrasound and community health workers can help find early, symptom-free heart failure in the emergency department. If you have risk factors like high blood pressure, diabetes, or obesity, you may be able to get early screening and support.
Chicago, IllinoisAges 45 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.