Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,051 recruiting studies in this area right now.
By phase
- Not applicable8,025
- Phase 2487
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts181
- Arizona175
- New York166
- Florida146
- Maryland120
- Minnesota120
- Texas120
- Illinois119
Recruiting studies10,048 total
- NCT07328230Recruiting
New procedure vs standard pill for adrenal-related high blood pressure
This study tests if a new procedure (blocking tiny adrenal arteries) works as well as a standard pill (spironolactone) for lowering high blood pressure caused by too much aldosterone from both adrenal glands. It is designed for people whose high blood pressure is due to idiopathic hyperaldosteronism.
Beijing, Beijing MunicipalityAges 15–60 - NCT07329075Recruiting
Soft robot for hand rehab after stroke
This study tests a soft, wearable robot to help people who had a stroke regain hand and finger movement. It is designed for those whose stroke happened at least 6 months ago, who still have some muscle activity in their hand, and who can sit for short periods.
Hong KongAges 18 years+ - NCT07329647Recruiting
Brain nutrition study for cognitive decline
This trial tests whether a nitrate-rich food supplement can improve blood flow in the brain and help thinking and memory. It is for people with small vessel disease in the brain or diabetes who are at risk for cognitive decline.
CoimbraAges 18 years+ - NCT07329699Recruiting
AI-Guided Heart Artery Pressure Test vs Standard Test
This study compares a new artificial intelligence (AI) method to measure blood flow in your heart arteries (called Medipixel FFR) with the standard invasive method. If you are scheduled for a heart angiogram or stenting and have a moderate blockage (40-90% narrowing) that doctors are unsure about, this AI tool may help decide the best treatment for you.
Seoul, Select StateAges 19 years+ - NCT07330622Recruiting
Register of heart artery reopening procedures
This registry tracks people who get a procedure to open a completely blocked heart artery (called a chronic total occlusion). It helps doctors learn more about these procedures and how to improve them.
BialystokAges 18 years+ - NCT07330635Recruiting
Chronic wounds and blood circulation checkup
This study checks how well blood flows in the legs of people with and without chronic wounds or circulation problems. It may help doctors better understand and treat poor circulation.
TaipeiAges 20–95 - NCT07330752Recruiting
First test of A3-Shield device for belly artery bulge
This trial tests a new device called the A3-Shield that is placed inside the belly's main artery to support a bulging area (aneurysm) and keep it from growing or bursting. It may be an option for patients whose aneurysm is large enough but not yet causing symptoms.
TashkentAges 18 years+ - NCT07330804Recruiting
Gene study: CORIN and high blood pressure in Afro-Caribbeans
This study looks at whether a specific gene (CORIN) is linked to high blood pressure in people of Afro-Caribbean descent in Guadeloupe. It compares people with high blood pressure to healthy volunteers to see if the gene is more common in those with hypertension.
Petit-BourgAges 18 years+ - NCT07331896Recruiting
Attention Training for Stroke Survivors with Spatial Neglect
This study tests a strategy-training program to help people who have had a stroke and struggle with spatial neglect (trouble paying attention to one side). The program is designed to improve attention and daily function. Participation involves coming to the University of Pittsburgh for training sessions.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07332234Recruiting
Optic nerve ultrasound for brain inflammation and pressure
This study uses a quick ultrasound of the optic nerve to help doctors detect swelling or pressure in the brain. It may help people with suspected meningitis, encephalitis, stroke, or brain tumors decide on the best treatment earlier.
Bucharest, BucharestAges 18–60 - NCT07333079Recruiting
Rehabilitation with biofeedback for stroke recovery
This study tests if adding biofeedback to standard rehabilitation improves hand and arm function after a stroke. Biofeedback uses sensors to show you how your muscles are working, helping you regain movement.
RzeszówAges 45–80 - NCT07333222Recruiting
Testing a suit to help movement after stroke or MS
This study tests whether wearing a special suit (Mollii) that sends gentle electrical pulses to the body can help improve movement, balance, and daily life for people who have had a stroke or have multiple sclerosis. The suit is meant to calm overactive muscles and help you move better.
Kaposvár, Somogy CountyAges 18–99 - NCT07333261RecruitingPhase 1
Study of BMS-986453 for newly diagnosed multiple myeloma
This trial tests a new drug, BMS-986453, for people newly diagnosed with multiple myeloma. It aims to see if the drug is safe and works well for those who cannot or choose not to have a stem cell transplant.
Birmingham, AlabamaAges 19 years+ - NCT07333430RecruitingPhase 1
CAR-T cell therapy for relapsed or refractory multiple myeloma
This trial tests a new CAR-T cell therapy (a type of immune cell treatment) for people with multiple myeloma that has come back or not responded to several prior treatments. It aims to see if this therapy can help control the disease.
JerusalemAges 18 years+ - NCT07333729Recruiting
Spinal anesthesia's effect on baby's nervous system during C-section
This study looks at how spinal anesthesia during a planned C-section may affect the baby's autonomic nervous system, which controls things like heart rate and breathing. It aims to help doctors better understand how to keep both mother and baby safe.
LilleAges 18–45 - NCT07334028Recruiting
Timing of infrared imaging for varicose veins
This study uses a special camera to take pictures of your leg veins at different times to find the best moment for imaging. It may help improve how varicose veins are diagnosed.
Guildford, SurreyAges 18 years+ - NCT07334457Recruiting
Platelet Changes While on ECMO Support
This study looks at how blood cells called platelets change in people who are on a heart-lung machine (ECMO) in the ICU. It aims to better understand how the body responds to this support.
StrasbourgAges 18 years+ - NCT07334691Recruiting
Trial of a new tricuspid valve replacement device
This trial tests a new catheter-based device to replace your tricuspid valve without open-heart surgery. It's for people with severe tricuspid regurgitation who are at high risk for surgery.
BonnAges 18–85 - NCT07334834Recruiting
Better cholesterol management for people with artery disease
This study tests a team-based approach to help people with artery disease (like heart attacks or leg blockages) get their cholesterol to a healthier level. If your LDL is above 70, you may benefit from extra support to manage your medications.
Aurora, ColoradoAges 18 years+ - NCT07334977RecruitingPhase 2
Brain and spinal cord stimulation after stroke or injury
This trial tests whether stimulating the brain and spinal cord together can help people recovering from stroke or spinal cord injury. It also includes a healthy control group for comparison.
BordeauxAges 18 years+ - NCT07335900Recruiting
Studying heart healing after TAVI with FAPI-PET scan
This study uses a special type of PET scan (FAPI-PET) to see how the heart heals after a less invasive valve replacement procedure called TAVI. It aims to help doctors better understand the changes in heart tissue after treatment for aortic stenosis.
ShanghaiAges 18 years+ - NCT07336225Recruiting
CMR Study for Heart Device Patients
This study looks at people who already had a heart MRI before getting a pacemaker, defibrillator, or other heart device. It aims to learn how MRI results might predict long-term outcomes for these patients.
BeijingAges 18 years+ - NCT07336394Recruiting
Study on rare heart muscle diseases using advanced MRI
This study uses a special heart MRI to better diagnose and understand rare heart muscle diseases. It may help doctors predict risks and make more accurate treatment decisions.
BeijingAges Any age - NCT07336823RecruitingEarly Phase 1
JY232 CAR-T cell therapy for relapsed multiple myeloma
This trial tests an investigational CAR-T cell therapy called JY232 for people with multiple myeloma that has returned or not responded to at least two prior treatments. The therapy targets a protein called BCMA on myeloma cells to help your immune system fight the cancer.
Foshan, GuangdongAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,051 recruiting cardiology studies from the U.S. registry right now, out of 15,491 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.