Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT07626411RecruitingPhase 3
Blood Thinner Study for Irregular Heartbeat
This study tests a new blood thinner to prevent strokes and blood clots in people with atrial fibrillation (a common heart rhythm problem). You may qualify if you have atrial fibrillation and at least one risk factor for stroke, or if you've never taken a blood thinner before.
Dothan, AlabamaAges 18 years+ - NCT06834594RecruitingPhase 4
Bleeding patterns in teens with Turner syndrome on progesterone
This study looks at how different ways of taking progesterone (a hormone given along with estrogen) affect bleeding patterns in teens with Turner syndrome. The goal is to find the best hormone schedule to cause regular, predictable periods.
Kansas City, MissouriAges 12–20 - NCT07209293Recruiting
Gastric suctioning during heart surgery with TEE
This study looks at using a tube to remove stomach contents during heart surgery that uses transesophageal echocardiography (TEE), a special ultrasound probe placed in the esophagus to see the heart. It aims to see if this improves the quality of the images.
Winston-Salem, North CarolinaAges 18 years+ - NCT07685522Recruiting
Vibrato clot removal for pulmonary embolism safety study
This trial tests the Vibrato Aspiration System, a device that suctions blood clots from the lungs in people with a recent pulmonary embolism (PE). It aims to see if the procedure is safe and works well for removing clots.
Poznan, Greater Poland VoivodeshipAges 18–75 - NCT07574593Recruiting
Heart Failure Sensor Implant Study
This study tests a small sensor placed in a vein to help monitor and manage heart failure. The sensor tracks fluid buildup in your heart and may help doctors adjust your treatment to keep you feeling better and out of the hospital.
Chula Vista, CaliforniaAges 18 years+ - NCT07771023Enrolling by invitation
Exercise for people who had aortic repair
This trial looks at whether a supervised exercise program can improve fitness and quality of life in adults who were born with a narrowed aorta (coarctation) and had surgery to fix it as a baby or child. It aims to see if exercise is safe and helpful for heart health and daily energy, without placing extra strain on the repaired area.
LjubljanaAges 18 years+ - NCT06532890Recruiting
Using microRNAs to personalize heart transplant medicines in children
This study is looking at heart transplant children (up to age 18) to see if measuring tiny molecules called microRNAs in the blood can help doctors personalize anti-rejection medicines. It aims to improve how we prevent rejection while reducing side effects.
Aurora, ColoradoAges Up to 18 years - NCT06416657Recruiting
General vs local anesthesia for brain aneurysm treatment
This trial compares general anesthesia (being fully asleep) to local anesthesia (only the area is numbed) during a procedure to treat an unruptured brain aneurysm with a flow diverter. It aims to find which approach is safer and works better.
Beijing, Beijing MunicipalityAges 18–80 - NCT05698732Recruiting
Coroflex stent study for selected small heart artery blockages
This trial studies a new heart stent (called Coroflex ISAR NEO) for people who need a procedure to open a narrowed coronary artery. It may help improve long-term results for patients with certain small, short blockages who can safely take the required blood-thinning medicines.
Aix-en-ProvenceAges 18 years+ - NCT07227311RecruitingPhase 2
Belantamab mafodotin combinations for relapsed multiple myeloma
This trial tests a new drug called belantamab mafodotin (a targeted antibody therapy) combined with standard treatments for multiple myeloma that has come back or stopped responding. It looks at three different drug combinations to see which works best for people who have had 1 or 2 prior treatments.
Los Alamitos, CaliforniaAges 18 years+ - NCT07312565Recruiting
Checking for belly aneurysms after brain aneurysm
This study checks if people who had a brain aneurysm (subarachnoid hemorrhage) later develop an abdominal aortic aneurysm, which is a bulge in the main artery in the belly. They will use an ultrasound to look at the abdominal aorta about a year or more after the brain bleed.
LeidenAges 18 years+ - NCT06898086Enrolling by invitation
TAVI with or without heart artery check for severe aortic stenosis
This trial compares two approaches for replacing a tight aortic heart valve (TAVI) through a leg artery: doing it with or without a routine check of your heart's arteries (coronary angiogram). If you have severe aortic stenosis and are scheduled for TAVI, this study helps find out whether skipping the artery check is safe and effective.
GrazAges 18 years+ - NCT07312383Recruiting
Skin blood flow study in leg artery disease
This trial uses a special device to measure tiny blood vessels in the skin of patients with severe leg artery disease. It aims to understand how blood flow changes before and after a common treatment to open blocked leg arteries (angioplasty).
OsloAges 18 years+ - NCT06601465RecruitingPhase 2
Vericiguat for cognitive health in heart failure
This study tests whether the heart failure medication vericiguat can also improve thinking and memory in people with heart failure who have mild cognitive problems. It involves taking vericiguat pills and having brain scans to track changes.
Calgary, AlbertaAges 18 years+ - NCT06871878Recruiting
Physiotherapy with telerehab after stroke
This trial tests a physiotherapy program that includes some sessions done at home using video calls. It aims to see if this extra therapy time can help improve arm and leg movement after a stroke.
BothwellAges 16 years+ - NCT07784751Enrolling by invitationPhase 1/Phase 2
Ultrasound therapy for stroke recovery
This study tests a new treatment that uses ultrasound pulses to help people recover after a stroke. It may improve movement or language abilities.
Taipei, TaiwanAges Any age - NCT07407738Recruiting
A trial of a shockwave device for calcified heart arteries
This trial tests a new device that uses sound waves to break up calcium deposits in heart arteries before placing a stent. It is for people with severely hardened arteries that are hard to treat with standard methods.
LyonAges 18 years+ - NCT07782216Recruiting
Studying brain proteins after acute brain injury
This study looks at how certain brain proteins (called biomarkers) behave in the blood after an acute brain injury. The goal is to see if these proteins can help doctors quickly assess the severity of the injury. Participation involves giving blood samples at specific times after your injury.
Pécs, BranyaAges 18 years+ - NCT06210698Recruiting
Angioedema biomarker research study
This study collects blood samples (and optional skin samples) from people with angioedema to learn more about the condition and find better ways to diagnose and treat it. If you join, you may help scientists understand angioedema better.
Wheaton, MarylandAges 12–75 - NCT00753974Recruiting
Heart and blood vessel tissue donation for research
This study collects heart and blood vessel tissue samples from people having heart surgery or from organ donors. The tissue is stored for future research to help understand and treat heart and blood vessel conditions.
Lexington, KentuckyAges Any age - NCT07781579Recruiting
MRI study to predict bleeding risk in moyamoya disease
This study uses advanced MRI scans to better predict the risk of bleeding in people with moyamoya disease, a rare condition where brain arteries narrow. It aims to improve prevention of bleeding strokes.
Beijing, Beijing MunicipalityAges Any age - NCT06568627RecruitingPhase 3
Testing a gel for cleaning leg ulcers
This study tests a new gel that helps remove dead tissue from venous leg ulcers. Venous leg ulcers are open sores on the leg that happen when veins don't work well. The gel is applied to the ulcer to clean it and help it heal. You may be able to join if you are an adult with a venous leg ulcer that is not too large and has been there for a few weeks.
Phoenix, ArizonaAges 18 years+ - NCT06509789Recruiting
Brain stimulation intensity for arm recovery after stroke
This trial tests whether a specific type of brain stimulation, called theta burst stimulation, can help improve arm movement in people who have had a stroke. It looks at how different intensities of the stimulation affect recovery.
Hong Kong, Hong KongAges 18–80 - NCT07782944Recruiting
CD38 PET scan for multiple myeloma
This study uses a special PET scan that looks for a protein called CD38 on myeloma cells to see if it can better find and track multiple myeloma compared to the standard PET scan. It might help doctors plan your treatment more precisely.
Guilin, GuangxiAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.