Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT03149705Recruiting
Study group of adults with ischemic stroke
This study looks at adults who have had an ischemic stroke confirmed on MRI and a blockage in a major brain artery. Researchers want to understand stroke care in people who can receive standard clot-busting treatment (thrombolysis) and/or clot removal (thrombectomy).
BronAges 18 years+ - NCT01805739Recruiting
Imaging tests for people before aortic valve replacement
This trial studies heart imaging tests (from multiple types of scans) for people who have a narrowed aortic valve and are being checked for a valve replacement through the catheter (often called TAVI). It may help doctors better plan the procedure and understand heart function before treatment.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT03521050Recruiting
Registry study of ICD leads implanted since 2006
This study keeps a long-term record of people who get an ICD (a device that helps treat dangerous heart rhythms) and its lead. It may help doctors learn how ICD leads perform over time.
LucerneAges Any age - NCT03972644Recruiting
Early valve replacement for people with severe but silent aortic narrowing
This trial tests whether replacing a badly narrowed aortic valve earlier—even when you feel fine—can prevent future heart problems. It compares early valve replacement (through a catheter or surgery) versus standard watchful waiting.
Odense, FynAges 18–85 - NCT03646955Recruiting
Partial breast radiation versus no radiation after lumpectomy
This trial compares giving radiation only to part of the breast versus not giving radiation at all after breast-conserving surgery. It’s meant for women with early, hormone-driven breast cancer to see if skipping radiation can be safe and reduce treatment burden.
SantiagoAges 60 years+ - NCT04538937Recruiting
Study of high eosinophils causing lung/airway damage
This registry study looks at adults with high eosinophils (a type of immune cell) that are believed to be causing damage in the airways or lungs. It aims to better identify these eosinophils and understand what is going on so future treatments can improve.
InnsbruckAges 18 years+ - NCT04599621Recruiting
Testing treatment for heart pain with anxiety or depression
This trial looks at people who have coronary artery disease and unstable or certain stable chest-pain symptoms, especially when anxiety or depressive symptoms are also present. The goal is to see how the study approach helps heart symptoms when mental health symptoms occur at the same time.
SamarkandAges Any age - NCT04454177Recruiting
Smartwatch help to discharge earlier after valve replacement
This study tests whether using a smartwatch can safely help people leave the hospital earlier after a transcatheter aortic valve replacement (TAVR). It checks comfort, safety, and follow-up at home.
Hangzhou, ZhejiangAges 18 years+ - NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT04603872RecruitingEarly Phase 1
CAR-T plus dasatinib for hard-to-treat B-cell cancers
This early study tests a cancer-fighting treatment that uses CAR-T cells together with dasatinib for people whose B-cell cancers have come back or did not respond. It aims to improve control of the cancer in cases that are often resistant to standard treatment.
Hangzhou, ZhejiangAges 18–70 - NCT04620642Recruiting
Registry for adults treated with clot-busting or clot removal
This trial is a registry that collects information from adults who were hospitalized for an ischemic stroke and received either clot-busting medicine or a procedure to remove the clot. It may help doctors better understand stroke treatments and outcomes.
LyonAges 18 years+ - NCT04634487Recruiting
Registry for takotsubo heart condition in Poland
This is a registry study that collects information from people diagnosed with takotsubo syndrome. It helps researchers better understand the condition and may improve care in the future.
WarsawAges Any age - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT04749927Recruiting
Image-based eye photos to study heart blood-vessel risks
This study uses deep learning (computer pattern recognition) to analyze retinal photos (pictures of the eye’s blood vessels). It aims to link what’s seen in the eye to heart and blood-vessel disease patterns, especially in people with higher cardiovascular risk.
SeoulAges 20–79 - NCT04653428Recruiting
German registry for repairing a severely leaky tricuspid valve
This study records patients who get a catheter-based repair for a severely leaky tricuspid heart valve. It helps doctors and researchers learn how these treatments work in real-world care.
MunichAges 18 years+ - NCT04675918Recruiting
Registry for children’s in-hospital cardiac arrest
This study collects information about children (from 1 month to 18 years) who have a cardiac arrest while in the hospital. The goal is to better understand what happens during these emergencies and improve care in the future.
MadridAges 1 month–18 years - NCT01384721Recruiting
CT scan study for heart artery disease risk
This study uses a CT heart scan (with a calcium score) to better understand risk in people with suspected coronary artery disease. You may be asked to have scan-based measurements and then be followed for at least a year.
Milan, MIAges 18 years+ - NCT03604133Recruiting
Registry for people getting a defibrillator implanted in a clinic
This trial is a registry that collects information about outcomes after getting an implantable cardioverter-defibrillator (a device that can help correct dangerous heart rhythms). You may be invited if your doctor recommends the implant to be done at an ambulatory surgical center (a same-day surgery clinic).
Lehi, UtahAges Any age - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80 - NCT03938155Recruiting
Risk check program for older women in Manitoba
This trial looks at how well a health risk assessment can identify heart and blood-vessel problems in women 55 and older. It may help doctors target prevention earlier, which could lower the chance of serious events.
Winnipeg, ManitobaAges 55 years+ - NCT04735003Recruiting
Transcatheter heart procedure for tricuspid valve leaking
This trial is studying a heart procedure that is done through catheters (not open-heart surgery) to treat a leaky tricuspid valve. It may help patients who have valve leakage and are candidates for this specific catheter-based approach, and who can return for follow-up visits.
Brescia, LombardyAges 18–100 - NCT01604395Recruiting
Long-term growth hormone check for children with short stature
This study follows children who are short for their age and checks how safe and effective growth hormone is over the long term. It may help families understand expected benefits and side effects for their specific growth-related condition.
SeoulAges 2 years+ - NCT04746534Recruiting
Study for blood-flow problems in the intestines
This study follows adults with intestinal blood-flow problems (from artery or vein issues) to better understand these conditions. It may help doctors plan future diagnosis and treatments for people with sudden or long-lasting intestinal ischemia.
ClichyAges 18 years+ - NCT02537769Recruiting
Surgery to fix a leaky tricuspid valve in LVAD patients
This study looks at whether fixing a mildly leaky tricuspid valve during LVAD surgery improves outcomes for people with advanced heart failure. It’s mainly aimed at patients who are already scheduled to receive an implantable LVAD.
Seattle, WashingtonAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.