Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT03837574Recruiting
Registry for people with Tetralogy of Fallot and a defibrillator
This is a national registry that collects information about people with Tetralogy of Fallot who have an implantable defibrillator. It helps researchers better understand outcomes and care needs in this specific group.
ParisAges 18 years+ - NCT03450577Recruiting
Bifurcation heart artery registry study for adults
This registry study looks at adults with a specific kind of blockage pattern where a heart artery splits. By collecting information about these cases, the study aims to better understand treatment and outcomes for this condition.
Novosibirsk, Novosibirsk OblastAges 18–100 - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT02138695Recruiting
Study of outcomes after atrial fibrillation catheter ablation
This study follows people after a procedure called catheter ablation to treat atrial fibrillation (an irregular heart rhythm). It aims to learn which factors help predict outcomes, so future care can be better tailored.
SeoulAges 19 years+ - NCT03488732Recruiting
Heart valve disease registry for people needing valve treatment
This study is a registry that collects information about people with severe heart valve problems who are planning to have a valve procedure. It may help doctors better understand your condition and treatment over time.
MünchenAges 18 years+ - NCT03880708Recruiting
Registry for inherited dangerous heart rhythm conditions
This study is a heart rhythm registry for people with inherited conditions that can cause abnormal heart beats. By collecting health and testing information, researchers hope to better understand these conditions and improve care.
Beijing, Beijing MunicipalityAges 1 hour–90 years - NCT03196414RecruitingPhase 1/Phase 2
CAR T cell therapy for relapsed myeloma with multiple targets
This trial tests an immune therapy made from T cells to attack multiple markers on multiple myeloma cells (including CD138 and BCMA). It may help people whose myeloma has come back or resisted treatment, when there are no curative options left.
Suzhou, JiangsuAges 18–75 - NCT03934957Recruiting
Study of health in people living in Hamburg
This study follows adults living in Hamburg to better understand health and health-related factors over time. You may help researchers learn what influences health in this age group.
HamburgAges 45–74 - NCT03959748Recruiting
Pulmonary hypertension patients’ heart-lung pressure database study
This study builds a database of people with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension. It may help doctors better understand these conditions in the Polish population and improve future care decisions.
KrakowAges 3 months+ - NCT03966443Recruiting
Fluciclovine PET/CT scan for people with multiple myeloma
This trial studies how a special PET/CT scan (using fluciclovine) may help doctors evaluate multiple myeloma. You might be eligible if you’re a candidate for stem cell transplant (ASCT).
OsloAges 18 years+ - NCT03975998Recruiting
Early mitral valve repair versus watchful waiting
This trial compares doing mitral valve repair early with closely monitoring symptoms instead, for people who have severe leakage but feel well. It may help determine whether early surgery prevents future heart problems without causing unnecessary risk.
AmsterdamAges 18–75 - NCT04006535Recruiting
Genetic testing study for vasculitis in families and children
This study uses a detailed DNA test to look for possible genetic causes of vasculitis (inflammation of blood vessels) in children and adults. It may help researchers better understand why vasculitis happens, especially in families.
Paris, Île-de-France RegionAges Any age - NCT03893734RecruitingPhase 4
Methadone vs hydromorphone to check heart rhythm after surgery
This trial tests whether the pain medicines methadone and hydromorphone affect the heart’s electrical timing after general anesthesia and surgery. It may help doctors choose the safer option for patients who need strong pain control after an operation.
Evanston, IllinoisAges 18–80 - NCT04036357Recruiting
Study of liver fat disease with heart and metabolism problems
This study looks at people with fatty liver disease and common health issues like obesity, diabetes, high blood pressure, or abnormal cholesterol. It may help researchers understand how liver fat and heart/metabolism problems relate and how they affect health over time.
RomeAges 18–80 - NCT03470246Recruiting
Wearable activity coaching after heart surgery
This study tests a personalized activity program and coaching after heart surgery, using wearable sensors to track movement. It may help you recover more safely and move in a goal-directed way during rehabilitation.
KuopioAges 30–90 - NCT02932007RecruitingPhase 2
Chloroquine to treat ongoing atrial fibrillation symptoms
This trial tests whether chloroquine can reduce symptoms in people with persistent atrial fibrillation (AF), an irregular heartbeat that lasts longer than a week. It will also closely monitor heart rhythm and safety, since the medicine can affect the heart and other organs.
Tampa, FloridaAges 18 years+ - NCT04076449Recruiting
MRI measurements for epilepsy from a single brain blood vessel lump
This study uses special MRI scans to measure brain changes in people whose seizures are related to one cerebral cavernous malformation (a type of abnormal blood vessel in the brain). It aims to find a measurable “biomarker” from MRI that may help understand the epilepsy and the brain structure around it.
Beijing, Beijing MunicipalityAges 18–70 - NCT04084132Recruiting
Testing earlier vs later valve replacement after repaired Tetralogy
This study compares doing a valve replacement earlier versus later in people born with Tetralogy of Fallot who already had heart surgery as babies. It may help decide the safest timing to protect heart function, especially right-sided pumping and valve leakage.
AarhusAges 12 years+ - NCT04087200Recruiting
High-dose statin early after heart attack to protect kidneys
This trial looks at whether starting a high dose of a statin (cholesterol medicine) right away after an acute coronary syndrome (a serious heart condition) can reduce future heart and kidney problems. It may help patients by testing a strategy meant to prevent complications soon after the event.
PratoAges Any age - NCT04098536Recruiting
Diesel exposure study of long-lasting inflammation and blood vessels
This study exposes healthy adults to diesel fumes to see how it affects inflammation (the body’s response to irritation) and blood vessels over time. It may help researchers understand health risks from diesel air pollution, though it is not for people with existing chronic health conditions.
Athens, AtticaAges 18–60 - NCT04088682Recruiting
Check hospital care quality for adults with heart attacks
This trial looks at how well hospitals measure and deliver care for adults who arrive soon after a certain type of heart attack. It may help improve quality of treatment for people with acute ST-elevation myocardial infarction (a specific heart attack pattern).
Beijing, Beijing MunicipalityAges 18 years+ - NCT04212520Recruiting
Using non-fasting cholesterol tests to predict heart events
This study looks at whether cholesterol levels measured without fasting can help predict future heart and blood vessel events in people living in the community. If you join, your non-fasting blood test results may be tracked to see how well they forecast cardiovascular risk.
Guangzhou, GuangdongAges 18 years+ - NCT04226612Recruiting
Link between inpatient blood pressure and in-hospital complications
This study looks at whether higher or lower blood pressure during a hospital stay is associated with complications during the same stay. It may help doctors better identify risk and improve monitoring.
Guangzhou, GuangdongAges Any age - NCT04227002Recruiting
Study for people with aortic valve problems
This trial is for people with aortic valve disease (aortic valve narrowing, leakage, or a worn-out valve). It tests what the doctors learn from following these patients, and it may help improve future care.
HamburgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.