Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT06045351RecruitingPhase 1
Vitamin D shots for women with PCOS and low vitamin D
This trial tests whether vitamin D injections can help females with polycystic ovary syndrome (PCOS) who also have low vitamin D levels. Participants will receive the injection and be monitored for changes in their condition.
Karachi, SindhAges 18–45 - NCT06398340Recruiting
Can a wearable device track what you eat?
This study uses a wearable device (like a smartwatch) to see if it can track what you eat. You would wear the device for a few days and report your meals. It is for generally healthy adults.
LondonAges 18–65 - NCT06645379Recruiting
Platelet-rich plasma for fertility treatments
This trial tests whether injecting platelet-rich plasma (a concentrate from your own blood) into the uterus or ovaries can help women with certain fertility issues, such as damaged uterine lining, scarring, or low egg reserve. It aims to improve pregnancy chances in these challenging cases.
Yiwu, ZhejiangAges 18–50 - NCT06833489Recruiting
Using genetic testing to find answers for rare muscle diseases
This study looks at leftover muscle tissue from people who have had genetic testing for rare muscle diseases but didn't get a clear diagnosis. The goal is to use newer genetic analysis to find the cause of their disease.
MarseilleAges Any age - NCT06833554Recruiting
Breast milk cells and infant health in mothers with metabolic conditions
This trial studies how special cells in breast milk from mothers with metabolic diseases (like obesity or diabetes) affect infant development and lung infection response after a nutritional intervention. It aims to understand if improving mother's diet can strengthen baby's immune system.
Málaga, MalagaAges 18–50 - NCT03989778RecruitingPhase 2
Vitamin D for PCOS with low vitamin D
This Phase 2 study tests whether vitamin D can improve hormone balance and infertility-related problems in people with PCOS who have low vitamin D. You may be able to join if you’re between 18 and 36, have primary infertility, and meet specific PCOS and vitamin D blood test levels.
Karachi, SindhAges 18–36 - NCT04390308Recruiting
Testing gentle stimulation of ovaries before fertility treatment
This trial studies whether a “mechanical stimulation” procedure can help small egg-making structures in the ovary start to work again in people with primary ovarian insufficiency. If the procedure shows signs of response, you may then move on to further fertility treatment, including IVF.
Abu Dhabi, Abu Dhabi EmirateAges 18–40 - NCT05956574Recruiting
Lifestyle coaching program for weight and health changes
This study tests whether a lifestyle and activity program can help people with higher body weight make healthier changes. You may be asked to track your habits on a smartphone and participate in walking and exercise activities.
Augusta, GeorgiaAges 18–40 - NCT06294990RecruitingPhase 4
Testosterone treatment for boys with Klinefelter syndrome in puberty
This trial tests if starting testosterone treatment during puberty (ages 10-14) helps boys with Klinefelter syndrome. It aims to understand how the hormone affects development and well-being.
CopenhagenAges 10–14 - NCT06427343RecruitingPhase 4
IV iron: low dose vs high dose for heart failure with low iron
This study compares two different doses of IV iron (low vs high) to see which works better for people with heart failure and low iron levels. It may help you feel less tired and breathe easier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06789705Recruiting
MDMA for people with vasopressin deficiency
This study tests whether a low dose of MDMA, compared to a placebo, changes oxytocin levels in people with a condition called arginine vasopressin deficiency (also known as central diabetes insipidus). The goal is to understand the role of oxytocin in this condition and explore potential treatment insights.
BaselAges 18 years+ - NCT03947697Recruiting
Electrical stimulation to help improve blood sugar control
This study tests whether electrical stimulation can improve blood sugar control in people who are overweight and not very active. It’s designed for people with low exercise habits and will compare how your blood sugar responds to the intervention.
El Paso, TexasAges 18 years+ - NCT06833749RecruitingPhase 2
Testing KBP-336 for knee osteoarthritis with obesity
This study tests an experimental medicine called KBP-336 for people with both obesity and knee osteoarthritis who still have significant knee pain despite standard treatments. It aims to see if KBP-336 can reduce pain and improve function.
BrnoAges 45 years+ - NCT07385547RecruitingPhase 1
Kidney function and drug levels study
This study looks at how different levels of kidney function affect the amount of a medication in the body. It may help doctors decide on the right dose for people with kidney problems.
Miami, FloridaAges 18–80 - NCT07386340Recruiting
Testing a new continuous glucose monitor with flash readings
This study tests a new sensor system that tracks glucose levels continuously and can give a quick reading when you wave a device over it. It aims to see if it's safe and accurate for people with diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07388602RecruitingPhase 3
New drug combo for newly diagnosed AL amyloidosis
This trial tests a new drug (SCTC21C) combined with three standard chemotherapy medicines for people who have just been diagnosed with AL amyloidosis. The goal is to see if adding the new drug helps reduce the abnormal protein deposits better than the standard treatment alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07387094RecruitingPhase 3
A study of XW003 for obesity with sleep apnea (no CPAP)
This trial tests an investigational weekly injection called XW003 for weight loss in people who have obesity and moderate-to-severe sleep apnea but do not use a CPAP machine. It aims to see if the drug can help with weight loss and improve sleep apnea without the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–75 - NCT07384104Enrolling by invitationPhase 1
Comparing a new bone drug (SAL023) to Evenity in healthy volunteers
This trial tests a new medicine called SAL023 to see how it compares to an approved drug (Evenity) in healthy people. It looks at how the body processes the drug, safety, and immune response. You must be healthy, within a certain age and weight range, and not have any bone or heart problems.
Hefei, AnhuiAges 18–45 - NCT06835426Recruiting
Imaging removed tissue during cancer surgery
This study tests a high-resolution PET-CT scanner that takes pictures of tissue removed during surgery to help doctors see if all the cancer has been removed. You might qualify if you are having surgery for a range of cancers including breast, prostate, thyroid, skin, gastrointestinal, or brain tumors.
Ghent, Oost VlaanderenAges 18 years+ - NCT06830187Recruiting
Bone density, vitamin D, and hearing loss in otosclerosis
This study looks at how bone density and vitamin D levels relate to hearing loss in people with otosclerosis, a condition where extra bone growth in the ear causes hearing problems. It may help doctors understand why some people lose more hearing than others.
AnkaraAges 18 years+ - NCT07387393Enrolling by invitation
PILI Pasifika Lifestyle Program for Native Hawaiian and Pacific Islander adults
This study tests a 3-month lifestyle program called PILI Pasifika, which includes healthy eating, physical activity, and support for social needs like housing or food. It aims to help Native Hawaiian and Pacific Islander adults with conditions like diabetes or high blood pressure improve their health in real-world settings.
Fayetteville, ArkansasAges 18 years+ - NCT07388420Recruiting
Adding evolocumab to standard lipid-lowering therapy for hypertriglyceridemia-induced acute pancreatitis
This trial tests if adding a medication called evolocumab to usual cholesterol-lowering treatment helps people who have had a specific type of pancreatitis caused by very high triglycerides (a type of fat in the blood). It aims to reduce triglyceride levels and prevent another episode.
Shenyang, LiaoningAges 18–75 - NCT07387185Recruiting
AI system for detecting chronic gut diseases
This trial tests an AI system to help detect and describe chronic diseases of the small intestine. If you are an adult having a small bowel endoscopy or capsule endoscopy, you may be able to join.
Pavia, PVAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.