Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT07379463Recruiting
PET/CT imaging study for people with cancer
This study uses a special PET/CT scan to look at amino acid transporters in tumors. It may help doctors better understand and diagnose certain cancers.
Hefei, AnhuiAges 18–90 - NCT07372820Recruiting
Metabolic changes after heart transplant and outcomes
This trial looks at how metabolism changes after a heart transplant and whether those changes affect your long-term health and recovery. It is for people who are planning to have or have already had a heart transplant.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07371767RecruitingEarly Phase 1
Gene editing for high triglycerides in kids with FCS
This trial tests a new gene-editing treatment (CS-121) for children and teens with a rare inherited condition called Familial Chylomicronemia Syndrome (FCS). It aims to lower very high triglyceride levels and reduce the risk of pancreatitis.
Shanghai, Shanghai MunicipalityAges 4–18 - NCT07375680Recruiting
Blood sugar and stomach emptying study before surgery
This study uses a simple stomach ultrasound before surgery to see how fast your stomach empties. It compares that to your HbA1c (a measure of average blood sugar) to better understand how diabetes might affect digestion during anesthesia.
Kütahya, KütahyaAges 18–70 - NCT07379333RecruitingPhase 3
Testing a new drug for type 2 diabetes when metformin and dapagliflozin aren't enough
This study tests a new medicine (HM11260C) to see if it helps people with type 2 diabetes who are already taking metformin and dapagliflozin but still have high blood sugar. If you qualify, it could give you a new option to better control your diabetes.
Gyeonggi-doAges 19 years+ - NCT07378033Enrolling by invitation
Body fat reduction and weight management study
This study tests a new approach to help with weight loss and body fat reduction. It may be a good fit if you are an adult with a BMI in the overweight to moderately obese range and you are not currently using weight-loss medications.
Bangalore, KarnatakaAges 19–65 - NCT07371793RecruitingPhase 1/Phase 2
Study of BBI-001 for healthy people and those with iron overload
This trial tests an experimental drug called BBI-001. It first looks at safety in healthy volunteers, then tests whether it can help people with hereditary hemochromatosis, a condition where the body stores too much iron.
Sydney, New South WalesAges 18–70 - NCT07377721RecruitingPhase 1
Study of HRS-2129 for diabetic nerve pain
This trial tests a new medicine called HRS-2129 for people with long-term nerve pain caused by diabetes. It aims to see if the drug can safely reduce pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07371104RecruitingPhase 1
Study of DWZ2501 in advanced BRCA ovarian cancer on olaparib
This trial compares how the body processes a new formulation of olaparib (DWZ2501) versus the standard version. It is for women with advanced, BRCA-mutated high-grade ovarian cancer who are already on or about to start a stable dose of olaparib 300 mg twice daily.
Seoul, Jongno-guAges 19 years+ - NCT07378956Recruiting
AI eye screening for diabetes patients
This study uses an artificial intelligence (AI) tool to analyze eye images in people with type 2 diabetes. The goal is to see if the AI can help detect early signs of diabetic eye disease, so you can get the right care sooner.
Incheon, Gyeonggi-doAges 19 years+ - NCT07371663RecruitingPhase 1/Phase 2
TCC1727 combination therapy for advanced solid tumors
This trial tests a new drug, TCC1727, combined with other treatments for people with advanced solid tumors that have stopped responding to standard therapy. It aims to see if these combinations can help shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06842459Recruiting
Helping older adults with diabetes stay mobile
This study tests a program to help older adults with diabetes who have trouble moving around. The goal is to see if a special care plan can help them stay independent and avoid getting worse.
Cagliari, CagliariAges 75–110 - NCT06842108Recruiting
Blood flow and heart-lung fitness in type 2 diabetes
This study looks at how blood flow changes (hemodynamics) affect your heart and lung fitness (cardiopulmonary fitness) in people with type 2 diabetes. It may help doctors understand how diabetes affects the heart and lungs.
Karachi, SindhAges 30–50 - NCT02674100Recruiting
Registry for pancreatic cancer patients getting a specific ablation
This is a research registry that collects information from adults with pancreatic cancer who are treated with an ablation procedure called irreversible electroporation (IRE). It may help doctors better understand which patients benefit from this approach and how the treatment is used in real life.
Birmingham, AlabamaAges 18 years+ - NCT03720197Recruiting
Registry for people living with type 1 diabetes
This is a registry that collects information from people living with type 1 diabetes. It may help researchers better understand the condition and improve future care.
Edmonton, AlbertaAges Any age - NCT04920812Recruiting
Testing multi-sample methods to diagnose mitochondrial muscle disease
This study looks for the cause of suspected mitochondrial diseases by combining multiple lab tests on muscle and skin samples, plus genetic testing results. If your current gene tests didn’t find an answer, this could help researchers learn what might be causing your condition.
Nice, CHU de NICEAges Any age - NCT05126147RecruitingPhase 4
Hydroxychloroquine for mild Graves’ eye swelling
This trial studies whether hydroxychloroquine can improve mild Graves’ orbitopathy (swelling and discomfort around the eyes). It’s meant for people with mild symptoms and who haven’t recently used certain eye or immune treatments.
HsinchuAges 18–75 - NCT06158503Recruiting
Blood Sugar Control and Bone Health in Type 1 Diabetes
This study tests whether using an automated insulin delivery system (a smart pump that adjusts insulin based on sensor readings) can help improve blood sugar control and bone health in adults with Type 1 diabetes who have high and unstable blood sugars.
Montreal, QuebecAges 18–100 - NCT05623007Recruiting
Diet and gut bacteria study for vaccinated teens with COVID
This trial tests whether changing diet can shift gut bacteria in overweight or obese teens after COVID-19 vaccination. The goal is to see if dietary changes can affect health markers related to the gut and immune system.
Jakarta Pusat, DKI JakartaAges 12–17 - NCT05942287Recruiting
Weight and weight loss study in heart failure with weak pumping
This study looks at how obesity and weight loss affect people living with heart failure where the heart pumping strength is reduced. It uses heart imaging (MRI) to measure the heart and may help clarify what weight changes do for symptoms and heart function.
Jersey, JerseyAges 18–85 - NCT06112340RecruitingPhase 2/Phase 3
Extension study of linsitinib for thyroid eye disease
This trial tests two doses of an oral medication (linsitinib) for people with active, moderate-to-severe thyroid eye disease who were in a previous study and didn't improve enough or had their bulging come back. It aims to see if continuing treatment can help with eye bulging and other symptoms.
Miami, FloridaAges 18 years+ - NCT06158529Recruiting
High-frequency spinal cord stimulation for diabetic nerve pain
This trial tests if a special type of spinal cord stimulation (high-frequency SCS) can better relieve painful nerve damage caused by diabetes. If you have long-term burning, stabbing, or electric-shock-like pain in both legs, this treatment may help reduce that pain.
BeijingAges 18–80 - NCT06452914Recruiting
Testing therapeutic socks for diabetic nerve pain
This study tests special socks with tiny electronic parts to see if they can reduce nerve pain, numbness, and tingling in people with diabetic neuropathy. If you have mild to moderate symptoms and are not taking new medications for it, you may be able to join.
Roswell, GeorgiaAges 18–79 - NCT06683391Recruiting
Improving Low Blood Sugar Guidelines for Type 1 Diabetes
This study is looking for adults with type 1 diabetes to help improve guidelines for preventing and treating low blood sugar (hypoglycemia). The goal is to make recommendations that are more practical and safer for people like you.
Montreal, QuebecAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.