Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT07367776Recruiting
Online education program for osteoporosis (RCT-PATOS)
This trial tests a digital education program for people with osteoporosis or osteopenia. It aims to help you learn more about your bone health and how to manage it, all from home using the 1177.se platform.
GävleAges 50 years+ - NCT07364630Recruiting
Placental membrane trial for diabetic and venous leg ulcers
This study tests whether a special wound dressing made from human placental membrane can help heal diabetic foot ulcers or venous leg ulcers that did not close with standard care. It is for people who were in the BIOCAMP trial and whose ulcer remained open after 12 weeks of standard treatment.
Philidelphia, PennsylvaniaAges 18 years+ - NCT07370194Recruiting
Study on high potassium levels in Brazil
This study is looking at how common high potassium levels (hyperkalaemia) are and what factors increase the risk for people with certain health conditions. It may help doctors better understand and manage this condition.
CuritibaAges 18 years+ - NCT07367971RecruitingPhase 1
ABP-671 interaction study for gout patients
This study tests how a new drug, ABP-671, interacts with allopurinol (a common gout medicine) in people with gout. It is looking for participants with normal or moderately reduced kidney function.
Cary, North CarolinaAges 18–75 - NCT07369076RecruitingPhase 1/Phase 2
Testing NB-4746 for people with ALS
This study tests an investigational drug called NB-4746 for people with ALS. The goal is to see if it can slow the progression of the disease. It is for people diagnosed within the last couple of years who are still able to eat and breathe on their own.
Concord, New South WalesAges 18–80 - NCT07368608RecruitingPhase 1/Phase 2
Testing a new drug for high blood pressure and cholesterol
This study tests a new medicine called BEBT-701 for people with mild to moderate high blood pressure and high cholesterol. The goal is to see if it can lower both blood pressure and LDL ('bad') cholesterol safely.
Changsha, HunanAges 18–60 - NCT07369011RecruitingPhase 3
Study of eloralintide for sleep apnea with obesity
This study tests an investigational medication called eloralintide to see if it can improve sleep apnea in people who are overweight or have obesity. You will receive either the study drug or a placebo (inactive shot), and your sleep and weight will be monitored over time.
Cullman, AlabamaAges 18 years+ - NCT07362355RecruitingPhase 2
New gout pill combined with febuxostat for high uric acid
This trial tests an experimental tablet (SHR4640) added to the standard gout medicine febuxostat (40 mg daily) for people whose uric acid remains too high despite febuxostat alone. The goal is to see if the combination lowers uric acid more effectively and safely.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07363148Recruiting
Study of MB-1 for weight and metabolic health in overweight adults
This study tests a new supplement called MB-1 to see if it can improve metabolic health in adults who are overweight or obese. If you are between 18 and 50, have a certain waist size, and have been at a stable weight for the last 3 months, you may qualify.
London, OntarioAges 18–50 - NCT06069258Recruiting
Movement Behaviors Among Bahraini Adults with Type 2 Diabetes
This study looks at how daily movement (like sitting, standing, and walking) affects blood sugar control in people with type 2 diabetes. It may help you understand your own activity patterns and how they relate to your diabetes management.
Building 10, Road 43, ManamaAges 20–75 - NCT06844370Recruiting
Home vs hospital NIV care for MND
This study compares two ways of starting non-invasive ventilation (NIV) — a breathing machine — for people with motor neurone disease (MND). It aims to see if starting NIV at home is as safe and effective as starting it in the hospital.
CambridgeAges 18 years+ - NCT05501483Recruiting
Study how fat differences may relate to type 2 diabetes
This study looks at differences in body fat to understand why some people develop type 2 diabetes. You may be asked for blood tests and health information to see if your diabetes risk and body fat patterns are linked.
StockholmAges 30–70 - NCT05682482RecruitingPhase 3
Combination T4/T3 vs T4 alone for autoimmune hypothyroid fatigue
This trial compares adding T3 (plus T4) versus taking only T4 to see if it improves severe ongoing tiredness in people with autoimmune hypothyroidism. You would stay on your thyroid medicine plan during the study and be monitored with blood tests and health checks.
Almere StadAges 18 years+ - NCT06773663RecruitingPhase 1/Phase 2
New imaging test for adrenal gland hormone disorder
This trial tests a special PET scan that may help doctors find the exact cause of high blood pressure related to an adrenal gland problem. It could help decide if surgery or medicine is the best treatment for you.
BeijingAges 18–80 - NCT06846411RecruitingPhase 4
Empagliflozin in newly untreated type 2 diabetes
This trial tests a medication called empagliflozin (a type 2 diabetes pill) to see how well it works in people with type 2 diabetes who have not taken any diabetes drugs for at least 8 weeks. If you qualify, you may receive the study drug and help researchers learn more about managing blood sugar.
SeongnamAges 20 years+ - NCT06271382Recruiting
Acupressure and foot exercises for type 2 diabetes
This study tests whether acupressure (a gentle pressure technique) and simple foot exercises can improve blood flow in the feet of people with type 2 diabetes. It may help prevent circulation problems.
BoluAges 18 years+ - NCT06367283RecruitingPhase 3
Metformin for treating hand osteoarthritis pain
This study tests whether metformin, a common diabetes medication, can reduce pain in hand osteoarthritis. You may be eligible if your hand pain is moderate to severe and you haven't taken metformin before.
Copenhagen, FrederiksbergAges 18 years+ - NCT07357701Recruiting
Genetic study for unexplained infertility in men and women
This study aims to find genetic causes of certain types of infertility in men and women. If you have been diagnosed with very low sperm count, no sperm, or early ovarian failure, researchers will look at your DNA to discover new genes that might be responsible.
Bethesda, MarylandAges 18–100 - NCT07358078Recruiting
Long-term study of ATTR-CM patients on vutrisiran or other approved therapies
This study observes people with ATTR-CM (a heart condition caused by a protein called transthyretin) who are starting treatment with vutrisiran or another approved therapy. It aims to understand how the disease progresses and how treatments work in real life.
Tucson, ArizonaAges 18 years+ - NCT07355738RecruitingPhase 1
Bioequivalence study of GZR18 injection
This study tests whether a change in the manufacturing process for GZR18 (an experimental injectable drug) affects how it works in the body. It may help determine if the new version is as safe and effective as the original.
Suzhou, SuzhouAges 18–50 - NCT07360418Recruiting
Follow-up study for healed diabetic foot ulcers
This trial checks if diabetic foot ulcers that healed during an earlier study stay closed over time. You can join only if your ulcer fully healed in that previous trial.
Clinton Township, MichiganAges 18 years+ - NCT07357428Recruiting
Brain-computer implant study for severe paralysis or speech loss
This study tests a brain-computer implant that might help people with severe paralysis or speech loss control a computer with their thoughts. It is for people who have trouble moving and speaking due to a progressive disease or injury.
Sacramento, CaliforniaAges 22–75 - NCT07360080Recruiting
Long-Term Effects of Teplizumab in Real-World Care
This study follows people who have already received teplizumab (a treatment to delay type 1 diabetes) to see how they do over time. It aims to understand the long-term effects in routine care.
Atlanta, GeorgiaAges Any age - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Mobile, AlabamaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.