Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT04196257RecruitingPhase 1
Early-dose trial of BP1001-A for advanced or recurrent solid tumors
This Phase 1 trial studies BP1001-A in people with advanced or recurring solid cancers to find a safe dose and learn how the treatment works. You may be asked for tumor biopsies before and possibly after treatment to see how the cancer responds.
Silver Spring, MarylandAges 18 years+ - NCT06475261Recruiting
Measuring tissue oxygen during surgery for ovarian cancer
This study measures oxygen levels in tissues during surgery for ovarian cancer that includes heated chemotherapy inside the abdomen. The goal is to understand how oxygen changes during the procedure, which could help improve care.
RomeAges 18–75 - NCT06728462Recruiting
Calcium supplement study for postmenopausal women with osteoporosis
This study tests a new form of calcium (amorphous calcium carbonate) to see if it can improve bone density in postmenopausal women with osteoporosis. It may offer an alternative for women who cannot or choose not to take other osteoporosis medications.
Kaohsiung CityAges 60–90 - NCT06590623Recruiting
How a ketone supplement affects your immune cells
This study tests what happens to your immune cells when you take a single dose of a common ingredient (ketone supplement) after not eating overnight. Researchers want to see if it changes how your immune system works at a molecular level.
Kelowna, British ColumbiaAges 19 years+ - NCT06852976RecruitingPhase 2
Gel treatment for diabetic foot ulcers study
This trial tests a new gel (MDI-1228-mesylate) applied to diabetic foot ulcers to see if it helps them heal faster than standard care alone. It is for people who have had a foot ulcer for at least 12 weeks and are already receiving standard treatment.
Durham, North CarolinaAges 18–75 - NCT06863532Recruiting
Comparing two add-on treatments for type 2 diabetes
This trial compares adding a new pill (cofrogliptin) to increasing your current metformin dose, for people whose blood sugar is still too high despite taking an SGLT2 inhibitor and a low dose of metformin. The goal is to see which option works better and is safer.
Hangzhou, ZhejiangAges 18–74 - NCT07326553RecruitingPhase 4
Placental membrane for diabetic foot ulcers
This trial tests whether a special placental membrane dressing helps diabetic foot ulcers heal faster. You may qualify if you have a diabetes-related foot ulcer that hasn't been healing well with standard care.
Phoenix, ArizonaAges 45–85 - NCT07325578Recruiting
Testing a new device for CT-guided spine and pelvis procedures
This study is testing a new device called EPIONE that helps doctors perform CT-guided needle procedures in the spine or pelvis. It aims to see if the device improves accuracy and safety for patients under general anesthesia.
San Diego, CaliforniaAges 22 years+ - NCT07334080RecruitingPhase 1
Study of how food affects ECC4703 in healthy adults
This trial tests how taking the study drug ECC4703 with or without food affects its levels in the body, and how well the body absorbs it. It helps find the best way to take the drug.
Adelaide, South AustraliaAges 18–65 - NCT07334119RecruitingPhase 1
Testing MT-304 for advanced HER2-positive tumors
This trial tests a new drug, MT-304, for people with advanced cancers that have high levels of a protein called HER2. It aims to see if the drug is safe and helps shrink tumors.
Darlinghurst, New South WalesAges 18 years+ - NCT07327281RecruitingPhase 1
Testing TQF3250 in healthy adults
This trial tests a new oral medication (TQF3250) in healthy adults to see how safe it is and how the body processes it. If you are a generally healthy Chinese volunteer, you may be able to help researchers learn about this potential treatment.
Nanjing, JiangsuAges 18–55 - NCT07331974Recruiting
A trial of Akkermansia for weight loss in overweight adults
This trial tests a supplement containing Akkermansia bacteria to see if it helps adults who are overweight or obese lose weight. It may be an option if you have not taken weight loss medications recently and are already trying to manage your weight with diet and exercise.
Guangzhou, GuangdongAges 18–60 - NCT06864130RecruitingPhase 4
Stopping Alendronate in osteoporosis after no fractures
This study wants to see if it is safe for postmenopausal women with osteoporosis to stop taking Alendronate after a long period of treatment without any new fractures. If you have been on Alendronate for a while and have stayed fracture-free, you may be able to take a break from the medicine.
AalborgAges Any age - NCT07332988Enrolling by invitation
Light therapy for dry eyes in Graves' disease
This trial tests if low-level light therapy can improve dry eye symptoms in people with Graves' disease whose dry eyes haven't gotten better with standard treatments like artificial tears.
Iași, IaşiAges 18 years+ - NCT07326891Recruiting
Mediterranean diet with cycling and rowing for blood sugar in prediabetic women
This trial tests whether following a Mediterranean diet and doing cycling and rowing exercise can help lower blood sugar in women with prediabetes. It may help you find a safe way to prevent or delay diabetes.
Beykoz, IstanbulAges 22–55 - NCT07333677RecruitingEarly Phase 1
Testing CAR-T therapy for severe graves' disease
This early-phase trial tests a new type of treatment called CAR-T cells (special immune cells made in a lab) to target and calm down the overactive immune system in people with severe Graves' disease that hasn't improved with standard medicines. It may offer a new option for those who have been on treatment for years or have had multiple relapses.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07327606Recruiting
Heart, kidney, and metabolism health study
This study follows people with different stages of heart-kidney-metabolic syndrome to understand what factors affect their health over time. It aims to find better ways to predict and manage the condition.
Beijing, Beijing MunicipalityAges 18–85 - NCT07325500RecruitingPhase 2
Low dose GLP-1 for heart health in HIV
This study tests a very low dose of a medication called a GLP-1 receptor agonist to see if it can improve heart and metabolic health in people with HIV who have excess weight.
Houston, TexasAges 18 years+ - NCT07329985Recruiting
Fear of low blood sugar in diabetes
This study looks at how afraid people with diabetes are of low blood sugar (hypoglycemia). It may help doctors understand your worries and improve care.
BilecikAges 18–65 - NCT07332273RecruitingPhase 3
Levothyroxine for weight loss in obesity
This trial tests whether adding levothyroxine (a thyroid hormone) to a low-calorie diet helps people with obesity lose more weight. It is for adults aged 25-60 with a BMI of 30-39.9 who have either mild underactive thyroid or normal thyroid but higher thyroid hormone levels in the normal range.
CadizAges 25–60 - NCT07333989Recruiting
Biofeedback training for balance in older adults with osteoporosis
This study tests whether biofeedback (using sensors to help you control your body movements) can improve balance in older adults with osteoporosis. If you have low bone density and are between 65-75 years old, this trial may help you strengthen your balance and reduce fall risk.
Abū ḨummuşAges 65–75 - NCT07332416Enrolling by invitation
Glucose monitor for postpartum diabetes screening
This study tests if a continuous glucose monitor can help screen for diabetes after pregnancy in people who had gestational diabetes. It aims to make screening easier and more comfortable than the traditional glucose drink test.
Winston-Salem, North CarolinaAges 18 years+ - NCT07328568Recruiting
Quick sprints for better heart health
This study tests whether short bursts of intense exercise can improve your heart and lung fitness. You might join if you're generally healthy and not already very active.
San Marcos, CaliforniaAges 18–55 - NCT07326111RecruitingPhase 4
Tirzepatide for PCOS and weight in women
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
BochumAges 18–45
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.