Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06989437RecruitingPhase 2/Phase 3
Study of Ponsegromab for Pancreatic Cancer with Weight Loss
This study tests an experimental drug called ponsegromab for people with advanced pancreatic cancer who experience severe weight loss and fatigue. It aims to see if the drug can help improve weight and energy levels while you continue standard chemotherapy.
Birmingham, AlabamaAges 18 years+ - NCT06984627RecruitingPhase 2
Study of Rilzabrutinib for Adults with Graves' Disease
This study tests an experimental pill called rilzabrutinib for people with Graves' disease, a condition where the immune system attacks the thyroid. It aims to see if the drug can help control the overactive thyroid and any related eye problems.
Buenos AiresAges 18–75 - NCT06983847Recruiting
Long-term study of Vitamin-C Injektopas in vitamin C deficiency
This study observes patients with vitamin C deficiency who receive Vitamin-C Injektopas 7.5 g over time to understand how it is used and its effects. It may help if you have low vitamin C levels.
Vienna, Etc., AustriaAges 18–120 - NCT06992596Recruiting
Brain implant study for controlling devices with thoughts
This trial tests a brain implant that lets you control external devices using your thoughts. It's for people with limited arm function due to spinal cord injury, stroke, ALS, or similar conditions.
Abu DhabiAges 18 years+ - NCT06993155RecruitingPhase 2
Leflutrozole for low testosterone and low sperm count
This trial tests a new drug called Leflutrozole to see if it can improve testicular function in men with low testosterone and low sperm count. The goal is to help increase natural hormone levels and sperm production.
North Hollywood, CaliforniaAges 18–49 - NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT06989164Recruiting
How Your Body Responds to Different Foods After Eating
This study looks at how different foods affect your body after eating, especially your blood sugar and other metabolic responses. It may help find personalized ways to eat better for your health.
Stanford, CaliforniaAges 18–80 - NCT06991296Recruiting
Omega-3 supplement study for adults with obesity
This study looks at how omega-3 supplements affect certain fats in the blood of adults with obesity. Researchers want to see if taking these supplements changes these fats in a helpful way.
Kannapolis, North CarolinaAges 45–60 - NCT06993051Enrolling by invitation
Social skills study for Portuguese preschool children
This study offers educational activities to help children from certain schools. It examines how these programs can improve health and learning outcomes.
BragaAges 3–6 - NCT06989593Recruiting
Storytelling study for parents of children with urogenital conditions
This study tests whether guided journaling (writing or dictating stories) can help parents cope and connect. It involves a 5-week journaling activity and one follow-up interview.
Boston, MassachusettsAges 18 years+ - NCT06985706RecruitingPhase 3
Comparing two treatments for diabetic eye swelling after initial injections
This trial tests whether switching from anti-VEGF injections to a special laser is better than continuing injections alone for people with diabetic macular edema whose central retinal thickness has dropped below 400 microns after the first year of treatment.
BedfordAges 18 years+ - NCT06984991Recruiting
Why some thyroid biopsy samples are hard to evaluate quickly
This trial looks at what makes it harder to quickly tell if a thyroid nodule sample is good enough for diagnosis during your biopsy. It may help doctors improve the procedure for people with suspicious nodules.
Asyut, Asyut GovernorateAges 18 years+ - NCT06993142Recruiting
Slowing Parkinson's Early With Exercise
This trial tests whether a specific exercise program can slow the early stages of Parkinson's disease in people who have a genetic risk (LRRK2 or GBA variants). You will use a smartphone app to guide your exercise from home.
Rochester, New YorkAges 50 years+ - NCT06989281Enrolling by invitation
Lifestyle medicine study for UAB patients
This study tests a lifestyle program offered in primary care to help patients manage conditions like diabetes, high blood pressure, high cholesterol, or psoriatic arthritis. It aims to see if this approach can improve health and well-being.
Birmingham, AlabamaAges 18–89 - NCT06988306Recruiting
Lifestyle program to prevent diabetes after pregnancy
This study tests a lifestyle program (like diet and activity guidance) to help prevent diabetes after pregnancy in people who had gestational diabetes. You'll be part of a home visiting program and learn ways to stay healthy.
San Luis Obispo, CaliforniaAges 18 years+ - NCT06984185Recruiting
Early detection of type 1 diabetes in children
This trial is looking for children with newly diagnosed type 1 diabetes to study how to detect the condition earlier. It focuses on kids who have already reached the stage where symptoms appear, to improve understanding of the disease.
Bron, RhôneAges 1–18 - NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT06989814Recruiting
Liquid biopsy test for Lynch syndrome cancer patients
This trial tests a simple blood test to measure tumor DNA in people with Lynch syndrome who have been newly diagnosed with cancer but haven't started treatment yet. It aims to see if this test can help monitor the cancer.
Leiden, South HollandAges 18 years+ - NCT06987903Recruiting
Exercise and breathing program before weight-loss surgery
This trial tests if a program of physical exercise and breathing exercises before bariatric surgery helps patients recover better. It is for people having surgery at the Álvaro Cunqueiro Hospital in Vigo.
Vigo, PontevedraAges 18–69 - NCT05866107Recruiting
App and smart scale program for weight loss in bipolar or schizophrenia
This study tests whether using a health app and smart body-fat scales helps people who are overweight or obese lose weight. It is designed for adults with bipolar disorder or schizophrenia who are stable and can safely follow the weight-loss and activity plan.
Beijing, Beijing MunicipalityAges 18–60 - NCT05740956RecruitingPhase 1
Drug study for cancers with HRR gene or HRD changes
This Phase 1 study tests HS-10502 in people with advanced solid tumors that have certain DNA repair problems (HRR or HRD). It may help by finding a safe dose and seeing whether the drug can shrink tumors in cancers that have specific genetic features.
Beijing, Beijing MunicipalityAges 18–75 - NCT05241249RecruitingPhase 2
Bethanechol plus chemotherapy for pancreatic cancer
This trial tests whether adding bethanechol to standard chemotherapy (gemcitabine and nab-paclitaxel) can work better for people with pancreatic ductal adenocarcinoma. You may be considered if your cancer is not spread and you can safely take the medicines and follow study visits.
New York, New YorkAges 18 years+ - NCT06653725RecruitingPhase 2
Ketone supplement study for hospitalized heart failure patients
This trial tests if a ketone supplement can help people hospitalized for acute heart failure. The supplement is given orally and aims to support the heart and energy levels during recovery.
AalborgAges 18 years+ - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.