Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT06843551RecruitingPhase 2
Testing a new immunotherapy combo for advanced pancreatic cancer
This trial is testing two immunotherapy drugs (balstilimab and botensilimab) to see if they can shrink tumors in people with advanced pancreatic cancer that has worsened after at least one prior treatment. If you have microsatellite stable (MSS) disease, you may be eligible.
Miami, FloridaAges 18 years+ - NCT06839677Recruiting
Quality of life after endoscopic vertical gastroplasty
This study looks at how people feel about their quality of life after a type of weight loss surgery called endoscopic vertical gastroplasty (GVE). If you had this surgery at least 6 months ago and can use a computer or tablet, you may be able to share your experience through a survey.
Roma, RMAges 18 years+ - NCT06839456RecruitingPhase 1/Phase 2
Stem cell addback to prevent infections after transplant
This trial tests whether adding back certain immune cells after a stem cell transplant can help prevent serious viral or fungal infections. It's for children and young adults up to age 25 who need a transplant for a blood cancer or other curable disease.
Philadelphia, PennsylvaniaAges 1 month–25 years - NCT06836284Recruiting
Extra support for teens in obesity treatment
This study is for teens aged 12–17 who are already being offered weight-loss medications. It adds extra support to see if that helps them do better with treatment.
LinköpingAges 12–17 - NCT06842732Recruiting
Text messages to prevent wasting in HIV-affected children in Kenya
This trial tests if two-way text messages (SMS) can help caregivers recognize early signs of malnutrition (wasting) in children who have HIV or were exposed to HIV but are uninfected. The goal is to prevent wasting and keep children healthy.
Homa BayAges 6 months–2 years - NCT06843811Enrolling by invitationPhase 2
Sirolimus for Leigh Syndrome
This trial tests if sirolimus can help people with Leigh syndrome. It aims to see if the drug can improve neurological symptoms and is looking for participants aged 6 months to 55 years.
Philadelphia, PennsylvaniaAges 6 months–55 years - NCT06841341Enrolling by invitation
Predicting breathing problems in ALS
This study uses ultrasound and electrical tests of breathing muscles and nerves to see if they can predict breathing failure in people with ALS. This could help doctors know when a patient might need breathing support.
Krakow, Lesser Poland VoivodeshipAges 18–80 - NCT06837181Recruiting
Understanding diabetes complications in cystic fibrosis
This study looks at how long-term diabetes affects people with cystic fibrosis. It helps researchers understand complications and improve care.
Birmingham, AlabamaAges 12 years+ - NCT06837805Enrolling by invitation
Produce prescription program for people with diabetes or prediabetes
This study provides free fruits and vegetables to adults with prediabetes or diabetes who are on Medicaid or eligible for SNAP. It aims to see if easier access to healthy food can improve your health.
Ames, IowaAges 18 years+ - NCT06843629Recruiting
PET scan test for MSLN in cancer patients
This study uses a special PET scan to look for a protein called MSLN in certain cancers like pancreatic, ovarian, and lung cancer. It aims to see if this imaging method can help doctors understand your tumor better.
Wuhan, HubeiAges 18–65 - NCT06836479Recruiting
Testing cultural meals for Asian Americans with type 2 diabetes
This study tests whether specially prepared meals that match your cultural background can help manage blood sugar levels. You'll wear a small sensor to track your glucose for 30 days and eat tailored meals for one week.
Stanford, CaliforniaAges 18 years+ - NCT06843330Recruiting
Lactate meter accuracy for children with GSD type Ia
This trial tests whether a simple finger-stick lactate meter gives accurate results for children and adults with a specific type of glycogen storage disease (GSD Ia). It aims to find a faster, easier way to monitor health during emergency visits or hospital stays.
Hartford, ConnecticutAges birth–60 years - NCT06844422RecruitingPhase 1/Phase 2
Guided radiation plus chemo and immune drug for pancreatic cancer
This study tests whether a new combination of super-precise radiation (guided SBRT), standard chemotherapy, and a newer immune medicine called Ivonescimab can slow or shrink pancreatic tumors that cannot be removed by surgery. The goal is to find a more effective treatment option.
Jinan, ShandongAges 18–75 - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT05439135Recruiting
Fecal microbiome transplant to treat malnutrition after GI surgery
This trial tests whether “washed microbiota transplant” (a treatment using processed gut bacteria) can improve malnutrition in adults who developed it after certain upper gut surgeries. It may help by restoring helpful gut bacteria, but you must meet several medical and safety checks.
Nanjing, JiangsuAges 18 years+ - NCT06447220Recruiting
Washed Microbiota Transplant for Malnutrition
This trial studies if a special, cleaned-up version of fecal transplant (called washed microbiota transplantation) helps treat malnutrition in adults. It is for people who have already had this transplant and have either lost a significant amount of weight or have a low body mass index (BMI).
Nanjing, JiangsuAges 18 years+ - NCT06662994RecruitingPhase 4
High dose aflibercept for diabetic macular edema after vitrectomy
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
Fullerton, CaliforniaAges 21 years+ - NCT06821802Recruiting
Protein supplement for low sodium from SIAD
This trial tests if a protein supplement can help patients with low sodium caused by a condition called SIAD. If you have SIAD and low sodium, you may be able to join.
BaselAges 18 years+ - NCT06829381Recruiting
Personalized one-anastomosis gastric bypass trial
This trial studies a personalized version of a common weight-loss surgery called One Anastomosis Gastric Bypass (OAGB). It aims to see if tailoring the surgery to each person improves results and safety.
Tel AvivAges 18 years+ - NCT06829563RecruitingPhase 1
Testing safety of new diabetes drug RZ-629
This early-phase study tests a new medicine called RZ-629. It looks at how safe it is, how the body processes it, and how it works in both healthy people and people with type 2 diabetes. If you have diabetes, you can join if your blood sugar is well controlled on your current pills.
AdelaideAges 18–65 - NCT06835569RecruitingPhase 1
ALTA3263 for advanced KRAS-mutated solid tumors
This trial tests an experimental pill called ALTA3263 for adults with advanced solid tumors that have a specific KRAS mutation. It's for people who have already tried other treatments or can't take them.
Orlando, FloridaAges 18 years+ - NCT06832410RecruitingPhase 3
Testing VX-880 for type 1 diabetes with a kidney transplant
This trial tests a new treatment called VX-880 for people who have had type 1 diabetes for at least 5 years and have already received a kidney transplant. The goal is to see if VX-880 can improve blood sugar control while you continue your current transplant medications.
Philadelphia, PennsylvaniaAges 18–65 - NCT06830343RecruitingPhase 1
Safety study of SYH9017 for overweight and obesity
This study tests a new medication called SYH9017 for people who are overweight or have obesity. It aims to see how safe the drug is, how well it is tolerated, and how the body processes it. Participants will receive either the drug or a placebo and be monitored closely.
Beijing, Beijing MunicipalityAges 18–60 - NCT06826339RecruitingPhase 4
Advanced wound treatments for diabetic foot and leg ulcers
This study compares several advanced wound treatments (called CAMPs) plus standard care to standard care alone for hard-to-heal diabetic foot ulcers and venous leg ulcers. It aims to see if the extra treatments help wounds close faster and prevent complications.
Monroeville, PennsylvaniaAges 21 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.